KEGG Orthology (KO)

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 Metabolism
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04341 Hedgehog signaling pathway - fly [PATH:ko04341]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
     04371 Apelin signaling pathway [PATH:ko04371]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04355  BDNF; brain-derived neurotrophic factor
       K04356  NTF3; neurotrophin 3
       K12457  NTF4; neurotrophin 4
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR, CD271; nerve growth factor receptor (TNFR superfamily member 16)
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16172  IRS1; insulin receptor substrate 1
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K06856  IGH; immunoglobulin heavy chain
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06465  CD19; B-lymphocyte antigen CD19
       K12230  PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
       K05438  GH; growth hormone
       K05439  PRL; prolactin
       K05418  OSM; oncostatin M
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05405  IL6; interleukin 6
       K05430  IL4; interleukin 4
       K05431  IL7; interleukin 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05437  EPO; erythropoietin
       K05423  CSF3, GCSF; granulocyte colony-stimulating factor
       K05080  GHR; growth hormone receptor
       K05081  PRLR; prolactin receptor
       K05057  OSMR; oncostatin M receptor
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K05055  IL6R, CD126; interleukin 6 receptor
       K05071  IL4R, CD124; interleukin 4 receptor
       K05072  IL7R, CD127; interleukin 7 receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05079  EPOR; erythropoietin receptor
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K06236  COL1A; collagen, type I, alpha
       K19719  COL2A; collagen, type II, alpha
       K06237  COL4A; collagen, type IV, alpha
       K06238  COL6A; collagen, type VI, alpha
       K08131  COL9A; collagen, type IX, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06248  CHAD; chondroadherin
       K06249  RELN; reelin [EC:3.4.21.-]
       K16857  THBS1; thrombospondin 1
       K04659  THBS2S; thrombospondin 2/3/4/5
       K05717  FN1; fibronectin 1
       K06250  SPP1, BNSP, OPN; secreted phosphoprotein 1
       K06251  VTN; vitronectin
       K06252  TN; tenascin
       K03900  VWF; von Willebrand factor
       K06253  IBSP; integrin binding sialoprotein
       K06480  ITGA1, CD49a; integrin alpha 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06483  ITGA4, CD49d; integrin alpha 4
       K06484  ITGA5, CD49e; integrin alpha 5
       K06485  ITGA6, CD49f; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV, CD51; integrin alpha V
       K05719  ITGB1, CD29; integrin beta 1
       K06493  ITGB3, CD61; integrin beta 3
       K06525  ITGB4, CD104; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K21290  PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K06071  PKN; protein kinase N [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
       K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
       K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K16339  THEM4, CTMP; thioesterase superfamily member 4
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09554  CDC37; cell division cycle protein 37
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16340  PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
       K10167  TCL1A; T-cell leukemia/lymphoma 1A
       K16836  TCL1B; T-cell leukemia/lymphoma 1B
       K16837  MTCP1; mature T-cell proliferation-1 type B1
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K06626  CCNE; G1/S-specific cyclin-E1
       K09408  FOXO3; forkhead box protein O3
       K16332  RBL2; retinoblastoma-like protein 2
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K02158  BAD; Bcl-2-antagonist of cell death
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator Bcl-2
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04735  RELA; transcription factor p65
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K09420  MYB, C-MYB; transcriptional activator Myb
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
     04152 AMPK signaling pathway [PATH:ko04152]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K08272  CAB39, MO25; calcium binding protein 39
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K05424  LEP; leptin
       K05062  LEPR, CD295; leptin receptor
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K19028  PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
       K19029  PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
       K01103  PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3  [EC:2.7.1.105 3.1.3.46]
       K19030  PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K00850  pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
       K07292  NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K13088  ELAVL1, HUR; ELAV-like protein 1
       K04503  CCND1; G1/S-specific cyclin-D1
       K06627  CCNA; cyclin-A
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K00021  HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K11262  ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14]
       K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
       K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14]
       K01578  MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
       K08765  CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
       K19523  CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
       K19524  CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K18341  TBC1D1; TBC1 domain family member 1
       K07877  RAB2A; Ras-related protein Rab-2A
       K07901  RAB8A, MEL; Ras-related protein Rab-8A
       K07903  RAB10; Ras-related protein Rab-10
       K07905  RAB11B; Ras-related protein Rab-11B
       K07881  RAB14; Ras-related protein Rab-14
       K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K06259  CD36; CD36 antigen
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07207  TSC2; tuberous sclerosis 2
       K07206  TSC1; tuberous sclerosis 1
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
     04150 mTOR signaling pathway [PATH:ko04150]
       K13780  SLC7A5, LAT1; solute carrier family 7 (L-type amino acid transporter), member 5
       K06519  SLC3A2, MDU1, CD98; solute carrier family 3, member 2
       K14995  SLC38A9; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9
       K02145  ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:3.6.3.14]
       K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
       K02148  ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
       K02149  ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
       K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
       K02151  ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
       K02152  ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K20397  LAMTOR1; ragulator complex protein LAMTOR1
       K20398  LAMTOR2; ragulator complex protein LAMTOR2
       K04370  LAMTOR3, MP1, MAP2K1IP1; ragulator complex protein LAMTOR3
       K20399  LAMTOR4; ragulator complex protein LAMTOR4
       K16344  LAMTOR5, HBXIP; ragulator complex protein LAMTOR5
       K09594  FLCN, BHD; folliculin
       K20400  FNIP1; folliculin-interacting protein 1
       K20401  FNIP2; folliculin-interacting protein 2
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K20402  DEPTOR; DEP domain-containing mTOR-interacting protein
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K11137  TELO2, TEL2; telomere length regulation protein
       K20403  TTI1; TELO2-interacting protein 1
       K10421  CLIP1, RSN; CAP-Gly domain-containing linker protein 1
       K20064  GRB10; growth factor receptor-bound protein 10
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K15705  RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K20404  DEPDC5; DEP domain-containing protein 5
       K20405  NPRL2; nitrogen permease regulator 2-like protein
       K20406  NPRL3; nitrogen permease regulator 3-like protein
       K20407  MIOS, MIO; WD repeat-containing protein mio
       K14299  SEH1; nucleoporin SEH1
       K20408  WDR24; WD repeat-containing protein 24
       K20409  WDR59; WD repeat-containing protein 59
       K14004  SEC13; protein transport protein SEC13
       K20394  SESN2; sestrin 2
       K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha
       K17532  STRADB; STE20-related kinase adapter protein beta
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K08272  CAB39, MO25; calcium binding protein 39
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K20396  TBC1D7; TBC1 domain family member 7
       K07208  RHEB; Ras homolog enriched in brain
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K04690  FZDN, fz3; frizzled
       K03068  LRP5_6; low density lipoprotein receptor-related protein 5/6
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
       K16172  IRS1; insulin receptor substrate 1
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K20410  MAPKAP1, SIN1; target of rapamycin complex 2 subunit MAPKAP1
       K08267  RICTOR; rapamycin-insensitive companion of mTOR
       K20411  PRR5; proline-rich protein 5
       K04513  RHOA; Ras homolog gene family, member A
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
     04144 Endocytosis [PATH:ko04144]
     04147 Exosome [BR:ko04147]
     04145 Phagosome [PATH:ko04145]
     04142 Lysosome [PATH:ko04142]
     04146 Peroxisome [PATH:ko04146]
     04140 Autophagy - animal [PATH:ko04140]
       K04526  INS; insulin
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K07831  MRAS; Ras-related protein M-Ras
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K07207  TSC2; tuberous sclerosis 2
       K07206  TSC1; tuberous sclerosis 1
       K15464  BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       K07208  RHEB; Ras homolog enriched in brain
       K07204  RAPTOR; regulatory associated protein of mTOR
       K20402  DEPTOR; DEP domain-containing mTOR-interacting protein
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K17606  IGBP1, TAP42; immunoglobulin-binding protein 1
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K08331  ATG13; autophagy-related protein 13
       K19730  ATG101; autophagy-related protein 101
       K17589  RB1CC1; RB1-inducible coiled-coil protein 1
       K17906  ATG2; autophagy-related protein 2
       K17908  WIPI, ATG18; autophagy-related protein 18
       K17907  ATG9; autophagy-related protein 9
       K21245  SUPT20H; transcription factor SPT20 homolog
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K02161  BCL2; apoptosis regulator Bcl-2
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02158  BAD; Bcl-2-antagonist of cell death
       K08334  BECN, VPS30, ATG6; beclin
       K21246  NRBF2; nuclear receptor-binding factor 2
       K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K17889  ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
       K17985  AMBRA1; activating molecule in BECN1-regulated autophagy protein 1
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K21247  TP53INP2; tumor protein p53-inducible nuclear protein 2
       K21248  VMP1; vacuole membrane protein 1
       K08491  STX17; syntaxin 17
       K21249  UVRAG; UV radiation resistance-associated gene protein
       K11248  SH3GLB1; endophilin-B1
       K19330  RUBCN; run domain Beclin-1 interacting and cysteine-rich containing protein
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K10802  HMGB1; high mobility group protein B1
       K21250  PRAP1; proline-rich acidic protein 1
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K18082  MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
       K18086  MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
       K17603  ZFYVE1; zinc finger FYVE domain-containing protein 1
       K08336  ATG12; ubiquitin-like protein ATG12
       K08339  ATG5; autophagy-related protein 5
       K17890  ATG16L1; autophagy-related protein 16-1
       K20868  ATG16L2; autophagy-related protein 16-2
       K08337  ATG7; ubiquitin-like modifier-activating enzyme ATG7
       K17888  ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
       K08343  ATG3; ubiquitin-like-conjugating enzyme ATG3
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K07920  RAB33B; Ras-related protein Rab-33B
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K08342  ATG4; cysteine protease ATG4 [EC:3.4.22.-]
       K06528  LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
       K07897  RAB7A; Ras-related protein Rab-7A
       K07898  RAB7B; Ras-related protein Rab-7B
       K08512  VAMP8; vesicle-associated membrane protein 8
       K08509  SNAP29; synaptosomal-associated protein 29
       K01379  CTSD; cathepsin D [EC:3.4.23.5]
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K01363  CTSB; cathepsin B [EC:3.4.22.1]
     04138 Autophagy - yeast [PATH:ko04138]
       K07827  KRAS, KRAS2; GTPase Kras
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K16314  ELM1; serine/threonine-protein kinase ELM1 [EC:2.7.11.1]
       K21157  SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]
       K21158  TOS3; serine/threonine-protein kinase TOS3 [EC:2.7.11.1]
       K12761  SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K08331  ATG13; autophagy-related protein 13
       K08329  ATG17; autophagy-related protein 17
       K21144  ATG31; autophagy-related protein 31
       K21143  ATG29; autophagy-related protein 29
       K17907  ATG9; autophagy-related protein 9
       K17906  ATG2; autophagy-related protein 2
       K17908  WIPI, ATG18; autophagy-related protein 18
       K17909  ATG23; autophagy-related protein 23
       K21141  ATG27; autophagy-related protein 27
       K08330  ATG11; autophagy-related protein 11
       K17260  ACTR2, ARP2; actin-related protein 2
       K18584  ACTR3, ARP3; actin-related protein 3
       K19800  SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K00654  SPT; serine palmitoyltransferase [EC:2.3.1.50]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K17606  IGBP1, TAP42; immunoglobulin-binding protein 1
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K17607  TIPRL, TIP41; type 2A phosphatase activator TIP41
       K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K09464  GCN4; general control protein GCN4
       K06655  PHO85; negative regulator of the PHO system [EC:2.7.11.22]
       K21197  PCL5, pas1; G1/S-specific cyclin
       K09243  UME6; transcriptional regulatory protein UME6
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K08334  BECN, VPS30, ATG6; beclin
       K08335  ATG14; autophagy-related protein 14
       K21145  ATG38; autophagy-related protein 38
       K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K00915  IPMK, IPK2; inositol-polyphosphate multikinase [EC:2.7.1.140 2.7.1.151]
       K07756  IP6K, IHPK; inositol-hexakisphosphate 5-kinase [EC:2.7.4.21]
       K18083  MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
       K08336  ATG12; ubiquitin-like protein ATG12
       K08337  ATG7; ubiquitin-like modifier-activating enzyme ATG7
       K08338  ATG10; ubiquitin-like-conjugating enzyme ATG10
       K17888  ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
       K08339  ATG5; autophagy-related protein 5
       K08340  ATG16; autophagy-related protein 16
       K17890  ATG16L1; autophagy-related protein 16-1
       K08343  ATG3; ubiquitin-like-conjugating enzyme ATG3
       K08342  ATG4; cysteine protease ATG4 [EC:3.4.22.-]
       K21155  VAM3; syntaxin VAM3
       K08502  VAM7; regulator of vacuolar morphogenesis
       K08493  VTI1; vesicle transport through interaction with t-SNAREs 1
       K08516  YKT6; synaptobrevin homolog YKT6
       K06027  NSF, SEC18; vesicle-fusing ATPase [EC:3.6.4.6]
       K15296  NAPA, SNAPA, SEC17; alpha-soluble NSF attachment protein
       K07897  RAB7A; Ras-related protein Rab-7A
       K20195  MON1; vacuolar fusion protein MON1
       K21156  CCZ1; vacuolar fusion protein CCZ1
       K20179  VPS11, PEP5; vacuolar protein sorting-associated protein 11
       K20180  VPS16; vacuolar protein sorting-associated protein 16
       K20181  VPS18, PEP3; vacuolar protein sorting-associated protein 18
       K20182  VPS33; vacuolar protein sorting-associated protein 33
       K20177  VPS3, TGFBRAP1; vacuolar protein sorting-associated protein 3
       K20178  VPS8; vacuolar protein sorting-associated protein 8
       K20183  VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
       K20184  VPS41; vacuolar protein sorting-associated protein 41
       K12479  VPS45; vacuolar protein sorting-associated protein 45
       K01381  PEP4; saccharopepsin [EC:3.4.23.25]
       K01336  E3.4.21.48; cerevisin [EC:3.4.21.48]
       K17900  ATG15, AUT5; lipase ATG15 [EC:3.1.1.3]
       K06902  UMF1; MFS transporter, UMF1 family
       K14209  SLC36A, PAT; solute carrier family 36 (proton-coupled amino acid transporter)
     04136 Autophagy - other eukaryotes [PATH:ko04136]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K08266  MLST8, GBL; target of rapamycin complex subunit LST8
       K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
       K08331  ATG13; autophagy-related protein 13
       K19730  ATG101; autophagy-related protein 101
       K08330  ATG11; autophagy-related protein 11
       K17606  IGBP1, TAP42; immunoglobulin-binding protein 1
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K17907  ATG9; autophagy-related protein 9
       K17906  ATG2; autophagy-related protein 2
       K17908  WIPI, ATG18; autophagy-related protein 18
       K08334  BECN, VPS30, ATG6; beclin
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
       K08336  ATG12; ubiquitin-like protein ATG12
       K08339  ATG5; autophagy-related protein 5
       K17890  ATG16L1; autophagy-related protein 16-1
       K08337  ATG7; ubiquitin-like modifier-activating enzyme ATG7
       K17888  ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
       K08343  ATG3; ubiquitin-like-conjugating enzyme ATG3
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K08342  ATG4; cysteine protease ATG4 [EC:3.4.22.-]
     04137 Mitophagy - animal [PATH:ko04137]
     04139 Mitophagy - yeast [PATH:ko04139]
     02048 Prokaryotic Defense System [BR:ko02048]
 
   Cell growth and death
 
   Cellular community - eukaryotes
 
   Cellular community - prokaryotes
 
   Cell motility
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K00693  GYS; glycogen synthase [EC:2.4.1.11]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K07189  PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
       K17453  PPP1R3F, R3F; protein phosphatase 1 regulatory subunit 3F
       K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
       K07190  PHKA_B; phosphorylase kinase alpha/beta subunit
       K02183  CALM; calmodulin
       K00688  PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]
       K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
       K07192  FLOT; flotillin
       K07193  APS, SH2B2; SH2B adapter protein 2
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K07194  RHOQ, TC10; Ras homolog gene family, member Q
       K07195  EXOC7, EXO70; exocyst complex component 7
       K07196  TRIP10, CIP4; thyroid hormone receptor interactor 10
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K11262  ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14]
       K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14]
       K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00844  HK; hexokinase [EC:2.7.1.1]
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07201  FOXO1; forkhead box protein O1
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K03841  FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
       K01596  E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K02158  BAD; Bcl-2-antagonist of cell death
       K06279  SHC1; SHC-transforming protein 1
       K17447  SHC2; SHC-transforming protein 2
       K17448  SHC3; SHC-transforming protein 3
       K17449  SHC4; SHC-transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K04695  SOCS2, CIS2; suppressor of cytokine signaling 2
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04697  SOCS4; suppressor of cytokine signaling 4
       K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
       K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
     04922 Glucagon signaling pathway [PATH:ko04922]
     04923 Regulation of lipolysis in adipocyte [PATH:ko04923]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04926 Relaxin signaling pathway [PATH:ko04926]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
     04924 Renin secretion [PATH:ko04924]
     04614 Renin-angiotensin system [PATH:ko04614]
     04925 Aldosterone synthesis and secretion [PATH:ko04925]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Aging
     04211 Longevity regulating pathway - mammal [PATH:ko04211]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K11420  EHMT; euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K08339  ATG5; autophagy-related protein 5
       K14756  KL; klotho [EC:3.2.1.31]
       K07206  TSC1; tuberous sclerosis 1
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
       K08331  ATG13; autophagy-related protein 13
       K17589  RB1CC1; RB1-inducible coiled-coil protein 1
       K19730  ATG101; autophagy-related protein 101
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K07205  EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       K03259  EIF4E; translation initiation factor 4E
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
       K07359  CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K02159  BAX; apoptosis regulator BAX
       K04451  TP53, P53; tumor protein p53
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
       K10141  SESN1_3; sestrin 1/3
       K20394  SESN2; sestrin 2
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
     04212 Longevity regulating pathway - worm [PATH:ko04212]
     04213 Longevity regulating pathway - multiple species [PATH:ko04213]
       K04526  INS; insulin
       K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase Kras
       K07828  NRAS; GTPase NRas
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K08339  ATG5; autophagy-related protein 5
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K19805  ILP7; insulin-like peptide 7
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K18644  EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
       K03283  HSPA1s; heat shock 70kDa protein 1/2/6/8
       K09542  CRYAB; crystallin, alpha B
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K19764  INS7; insulin-like neuropeptide
       K08035  FOXA2, HNF3B; forkhead box protein A2, hepatocyte nuclear factor 3-beta
       K19766  HSP16.1; heat shock protein Hsp-16.1/Hsp-16.11
       K19767  HSP16.49; heat shock protein Hsp-16.48/Hsp-16.49
       K19768  HSP12.6; heat shock protein 12.6
       K19769  SIP1; stress-induced protein 1
       K12762  GPR1; G protein-coupled receptor GPR1
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K09468  MSN2_4; zinc finger protein MSN2/4
       K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:2.7.11.1]
       K19798  GIS1; transcriptional activator/repressor GIS1
       K19800  SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
       K03695  clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
       K01440  PNC1; nicotinamidase [EC:3.5.1.19]
       K11121  SIR2; NAD-dependent histone deacetylase SIR2 [EC:3.5.1.-]
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
       K17002  MIR17; microRNA 17
       K17003  MIR18A; microRNA 18a
       K17005  MIR19; microRNA 19
       K17006  MIR20A; microRNA 20a
       K17008  MIR92A; microRNA 92a
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K17010  MIR221; microRNA 221
       K17011  MIR222; microRNA 222
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K16863  MIR21; microRNA 21
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16980  MIRLET7; microRNA let-7
       K17397  MIRLET7C; microRNA let-7c
       K07827  KRAS, KRAS2; GTPase Kras
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K09283  HMGA2; high mobility group AT-hook protein 2
       K17396  MIR107; microRNA 107
       K16986  MIR15A; microRNA 15a
       K16987  MIR15B; microRNA 15b
       K16988  MIR16; microRNA 16
       K04503  CCND1; G1/S-specific cyclin-D1
       K10151  CCND2; G1/S-specific cyclin-D2
       K06626  CCNE; G1/S-specific cyclin-E1
       K16978  MIR126; microRNA 126
       K04438  CRK, CRKII; proto-oncogene C-crk
       K16972  MIR1; microRNA 1
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K16995  MIR29A; microRNA 29a
       K16996  MIR29B; microRNA 29b
       K16997  MIR29C; microRNA 29c
       K17398  DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
       K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
       K16970  MIR133A; microRNA 133a
       K16971  MIR133B; microRNA 133b
       K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
       K02163  BCLW; apoptosis regulator BCL-W
       K16974  MIR145; microRNA 145
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05448  VEGFA; vascular endothelial growth factor A
       K17017  MIR200C; microRNA 200c
       K17018  MIR141; microRNA 141
       K13376  TGFB2; transforming growth factor beta-2
       K17116  MIR183; microRNA 183
       K08007  VIL2; villin 2 (ezrin)
       K16993  MIR125A; microRNA 125a
       K16994  MIR125B; microRNA 125b
       K16865  PDCD4; programmed cell death protein 4
       K17023  MIR143; microRNA 143
       K17131  MIR192; microRNA 192
       K17371  MIR194; microRNA 194
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K17167  MIR215; microRNA 215
       K17366  MIR28; microRNA 28
       K17110  MIR30A_D_E; microRNA 30a/d/e
       K17111  MIR30B; microRNA 30b
       K17040  MIR30C; microRNA 30c
       K10373  TPM1; tropomyosin 1
       K17383  SPRY2; protein sprouty homolog 2
       K02161  BCL2; apoptosis regulator Bcl-2
       K10139  SERPINB5; serpin B5
       K17009  MIR155; microRNA 155
       K16975  MIR203; microRNA 203
       K17150  MIR205; microRNA 205
       K09299  ZEB1_2; zinc finger homeobox protein 1/2
       K17112  MIR27A; microRNA 27a
       K17113  MIR27B; microRNA 27b
       K08670  ST14, PRSS14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
       K07410  CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
       K17183  MIR31; microRNA 31
       K17367  MIR99A; microRNA 99a
       K17041  MIR100; microRNA 100
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K07436  CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K10149  TP63; tumor protein p63
       K16976  MIR375; microRNA 375
       K17379  MIR602; microRNA 602
       K09850  RASSF1; Ras association domain-containing protein 1
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K08270  DDIT4, REDD1; DNA-damage-inducible transcript 4
       K17460  BMF; Bcl-2-modifying factor
       K17042  MIR224; microRNA 224
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K17036  MIR363; microRNA 363
       K17378  MIR494; microRNA 494
       K17380  MIR615; microRNA 615
       K17381  MIR625; microRNA 625
       K17038  MIR25; microRNA 25
       K16982  MIR34A; microRNA 34a
       K17114  MIR96; microRNA 96
       K16864  MIR10A; microRNA 10a
       K17165  MIR23A; microRNA 23a
       K17394  MIR23B; microRNA 23b
       K17395  MIR23C; microRNA 23c
       K17020  MIR122; microRNA 122
       K13863  SLC7A1, ATRC1; solute carrier family 7 (cationic amino acid transporter), member 1
       K10145  CCNG1; cyclin G1
       K00510  HMOX1; heme oxygenase 1 [EC:1.14.14.18]
       K17024  MIR150; microRNA 150
       K17001  MIR223; microRNA 223
       K04381  STMN1; stathmin
       K17132  MIR342; microRNA 342
       K17376  MIR423; microRNA 423
       K04692  STAT3; signal transducer and activator of transcription 3
       K04377  MYC; Myc proto-oncogene protein
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K17119  MIR199B; microRNA 199b
       K17152  MIR324; microRNA 324
       K17137  MIR483; microRNA 483
       K16984  MIR26A; microRNA 26a
       K16985  MIR26B; microRNA 26b
       K17370  MIR152; microRNA 152
       K00558  DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
       K17144  MIR135; microRNA 135
       K02085  APC; adenomatosis polyposis coli protein
       K16172  IRS1; insulin receptor substrate 1
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K17015  MIR200A; microRNA 200a
       K17016  MIR200B; microRNA 200b
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K17461  RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs
       K17126  MIR124; microRNA 124
       K17369  MIR137; microRNA 137
       K17130  MIR128; microRNA 128
       K06620  E2F3; transcription factor E2F3
       K17365  MIR7; microRNA 7
       K07187  IRS2; insulin receptor substrate 2
       K17372  MIR326; microRNA 326
       K02599  NOTCH1; Notch 1
       K20994  NOTCH2; Notch 2
       K20995  NOTCH3; Notch 3
       K20996  NOTCH4; Notch 4
       K11459  PCGF4, BMI1; polycomb group RING finger protein 4
       K17012  MIR146A; microRNA 146a
       K07996  MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
       K17025  MIR181A; microRNA 181a
       K17026  MIR181B; microRNA 181b
       K17027  MIR181C; microRNA 181c
       K17028  MIR181D; microRNA 181d
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K17000  MIR373; microRNA 373
       K17175  MIR520; microRNA 520
       K06256  CD44; CD44 antigen
       K16989  MIR103; microRNA 103
       K11592  DICER1, DCR1; endoribonuclease Dicer [EC:3.1.26.-]
       K02329  FZD3; frizzled 3
       K06484  ITGA5, CD49e; integrin alpha 5
       K05762  RDX; radixin
       K04513  RHOA; Ras homolog gene family, member A
       K17148  MIR193B; microRNA 193b
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K17442  ZFPM2, FOG2; zinc finger protein ZFPM2
       K06493  ITGB3, CD61; integrin beta 3
       K10577  UBE2I, UBC9; ubiquitin-conjugating enzyme E2 I
       K17033  MIR335; microRNA 335
       K06252  TN; tenascin
       K16973  MIR206; microRNA 206
       K17172  MIR451; microRNA 451
       K05658  ABCB1, CD243; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]
       K17375  MIR345; microRNA 345
       K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
       K17151  MIR214; microRNA 214
       K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
       K17035  MIR106B; microRNA 106b
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K17178  MIR210; microRNA 210
       K16857  THBS1; thrombospondin 1
       K17391  IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
       K12035  TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
       K16977  MIR9; microRNA 9
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K17118  MIR199A; microRNA 199a
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K04364  GRB2; growth factor receptor-binding protein 2
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K10127  MDM4, MDMX; protein Mdm4
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K17129  MIR101; microRNA 101
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K17029  MIR195; microRNA 195
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K03099  SOS; son of sevenless
       K06279  SHC1; SHC-transforming protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17368  MIR129; microRNA 129
       K17449  SHC4; SHC-transforming protein 4
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K17039  MIR32; microRNA 32
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K12561  MARCKS; myristoylated alanine-rich C-kinase substrate
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K17377  MIR449A; microRNA 449a
       K11430  EZH2; histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43]
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K11411  SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-]
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K17373  MIR330; microRNA 330
       K17374  MIR331; microRNA 331
       K17390  CDCA5; sororin
       K17387  KIF23; kinesin family member 23
       K17389  MIR520C; microRNA 520c
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K15379  SLC45A3; solute carrier family 45, member 3
       K07606  VIM; vimentin
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05225 Hepatocellular carcinoma [PATH:ko05225]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05224 Breast cancer [PATH:ko05224]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: October 17, 2017