 Metabolism
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Genetic Information Processing
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Environmental Information Processing
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 Cellular Processes
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Transport and catabolism
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Cell motility
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Cell growth and death
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Cell communication
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04510 Focal adhesion [PATH:ko04510]
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04520 Adherens junction [PATH:ko04520]
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04530 Tight junction [PATH:ko04530]
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04540 Gap junction [PATH:ko04540]
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 K07372 GJA1, CX43; gap junction protein, alpha 1
K07373 GJD2; gap junction delta-2 protein
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7, ERK5; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05701 TJP1, ZO1; tight junction protein 1
K04141 ADRB1; adrenergic receptor beta-1
K04144 DRD1; dopamine receptor D1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04145 DRD2; dopamine receptor D2
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
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Organismal Systems
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Immune system
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Endocrine system
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Circulatory system
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Digestive system
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04970 Salivary secretion [PATH:ko04970]
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K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13504 VAMP2; vesicle-associated membrane protein 2
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04963 RYR3; ryanodine receptor 3
K02183 CALM; calmodulin
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K01242 CD38_157; NAD+ nucleosidase [EC:3.2.2.5]
K13879 BEST2, VMD2L1; bestrophin-2
K09867 AQP5; aquaporin-5
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K10951 SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
K04945 KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K13855 SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K04975 TRPV6; transient receptor potential cation channel subfamily V member 6
K13908 MUC5B, MG1; mucin-5B
K13909 MUC7, MG2; mucin-7
K13910 PRH1_2; salivary acidic proline-rich phosphoprotein 1/2
K13911 PRB1_2; basic salivary proline-rich protein 1/2
K13912 DMBT1; deleted in malignant brain tumors 1 protein
K13897 CST1; cystatin-SN
K13898 CST2; cystatin-SA
K13899 CST3; cystatin-C
K13900 CST4; cystatin-S
K13901 CST5; cystatin-D
K13913 HTN; histatin
K13914 STATH; statherin
K13915 LYZ; lysozyme C [EC:3.2.1.17]
K12550 LPO; lactoperoxidase [EC:1.11.1.7]
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
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04971 Gastric acid secretion [PATH:ko04971]
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04972 Pancreatic secretion [PATH:ko04972]
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04976 Bile secretion [PATH:ko04976]
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04973 Carbohydrate digestion and absorption [PATH:ko04973]
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04974 Protein digestion and absorption [PATH:ko04974]
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04975 Fat digestion and absorption [PATH:ko04975]
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04977 Vitamin digestion and absorption [PATH:ko04977]
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04978 Mineral absorption [PATH:ko04978]
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Excretory system
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Nervous system
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04724 Glutamatergic synapse [PATH:ko04724]
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04727 GABAergic synapse [PATH:ko04727]
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04725 Cholinergic synapse [PATH:ko04725]
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04728 Dopaminergic synapse [PATH:ko04728]
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04726 Serotonergic synapse [PATH:ko04726]
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04720 Long-term potentiation [PATH:ko04720]
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04730 Long-term depression [PATH:ko04730]
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K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K08067 GSBS; G substrate
K03456 PPP2R1; protein phosphatase 2 (formerly 2A), regulatory subunit A
K04382 PPP2C; protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K05207 GRID2; glutamate receptor delta-2 subunit
K04603 GRM1; metabotropic glutamate receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04535 GNAZ; guanine nucleotide-binding protein G(z) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K05256 CRH; corticotropin-releasing hormone
K04578 CRHR1; corticotropin releasing hormone receptor 1
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
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04723 Retrograde endocannabinoid signaling [PATH:ko04723]
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04721 Synaptic vesicle cycle [PATH:ko04721]
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04722 Neurotrophin signaling pathway [PATH:ko04722]
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Sensory system
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04744 Phototransduction [PATH:ko04744]
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04745 Phototransduction - fly [PATH:ko04745]
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04740 Olfactory transduction [PATH:ko04740]
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K04257 OLFR; olfactory receptor
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08327 PDC; phosducin
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02183 CALM; calmodulin
K08328 GUCA1; guanylate cyclase activator 1
K04950 CNGA3; cyclic nucleotide gated channel alpha 3
K04951 CNGA4; cyclic nucleotide gated channel alpha 4
K04952 CNGB1; cyclic nucleotide gated channel beta 1
K05027 CLCA1; calcium-activated chloride channel regulator 1
K05028 CLCA2; calcium-activated chloride channel regulator 2
K05030 CLCA4; calcium-activated chloride channel regulator 4
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04742 Taste transduction [PATH:ko04742]
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Development
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Environmental adaptation
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04710 Circadian rhythm [PATH:ko04710]
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04713 Circadian entrainment [PATH:ko04713]
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K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04445 MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K16513 NOS1AP, CAPON; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04587 ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04286 MTNR1B; melatonin receptor type 1B
K04285 MTNR1A; melatonin receptor type 1A
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K02633 PER; period circadian protein
K04379 FOS; proto-oncogene protein c-fos
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04711 Circadian rhythm - fly [PATH:ko04711]
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04712 Circadian rhythm - plant [PATH:ko04712]
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04626 Plant-pathogen interaction [PATH:ko04626]
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Human Diseases
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KEGG Orthology (KO)