KEGG Orthology (KO)

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 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ko00061]
     00062 Fatty acid elongation [PATH:ko00062]
     00071 Fatty acid degradation [PATH:ko00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ko00072]
     00073 Cutin, suberine and wax biosynthesis [PATH:ko00073]
     00100 Steroid biosynthesis [PATH:ko00100]
     00120 Primary bile acid biosynthesis [PATH:ko00120]
     00121 Secondary bile acid biosynthesis [PATH:ko00121]
     00140 Steroid hormone biosynthesis [PATH:ko00140]
       K00498  CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
       K00512  CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.99.9 4.1.2.30]
       K01131  STS; steryl-sulfatase [EC:3.1.6.2]
       K01015  SULT2B1; alcohol sulfotransferase [EC:2.8.2.2]
       K00513  CYP21A; steroid 21-monooxygenase [EC:1.14.99.10]
       K00070  HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
       K01822  E5.3.3.1; steroid delta-isomerase [EC:5.3.3.1]
       K12343  SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
       K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
       K12345  SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]
       K00089  E1.1.1.213; 3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.64 1.1.1.188 1.1.1.213]
       K00497  CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
       K07433  CYP11B2; steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
       K00251  AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
       K00037  E1.1.1.50; 3-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.50]
       K15680  HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
       K00071  HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
       K00038  E1.1.1.53; 3alpha(or 20beta)-hydroxysteroid dehydrogenase [EC:1.1.1.53]
       K05295  E1.1.1.149; 20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
       K07430  CYP7B; oxysterol 7-alpha-hydroxylase [EC:1.14.13.100]
       K01016  SULT1E1, STE; estrone sulfotransferase [EC:2.8.2.4]
       K01130  E3.1.6.1, aslA; arylsulfatase [EC:3.1.6.1]
       K00044  HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
       K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
       K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
       K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
       K13370  HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
       K10251  HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
       K07408  CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
       K07409  CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
       K07412  CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K07414  CYP2D; cytochrome P450, family 2, subfamily D [EC:1.14.14.1]
       K17690  CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5 [EC:1.14.14.1]
       K17691  CYP3A7; cytochrome P450, family 3, subfamily A, polypeptide 7 [EC:1.14.14.1]
       K07424  CYP3A; cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K17689  CYP3A4; cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
       K07410  CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
       K07434  CYP19A; aromatase [EC:1.14.14.14]
       K00489  CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.13.17]
       K00699  UGT; glucuronosyltransferase [EC:2.4.1.17]
       K00545  COMT; catechol O-methyltransferase [EC:2.1.1.6]
       K05296  E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
       K10207  HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
     00561 Glycerolipid metabolism [PATH:ko00561]
     00564 Glycerophospholipid metabolism [PATH:ko00564]
     00565 Ether lipid metabolism [PATH:ko00565]
     00600 Sphingolipid metabolism [PATH:ko00600]
     00590 Arachidonic acid metabolism [PATH:ko00590]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1 [EC:3.1.1.32 3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K15729  PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
       K05309  PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
       K15730  PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
       K00079  CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
       K00081  CBR2; carbonyl reductase 2 [EC:1.1.1.184]
       K00084  CBR3; carbonyl reductase 3 [EC:1.1.1.184]
       K15717  K15717; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
       K01832  TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
       K01830  E5.3.99.2, PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.64 1.1.1.188 1.1.1.213]
       K01831  PTGIS, CYP8A; prostacyclin synthase [EC:5.3.99.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K01254  LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
       K17726  CYP4F2_3; leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]
       K00807  LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
       K18592  GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
       K00432  E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K07422  CYP2U1; cytochrome P450, family 2, subfamily U, polypeptide 1
       K17687  CYP4A11; alkane 1-monooxygenase [EC:1.14.15.3]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K17721  CYP2C19; cytochrome P450, family 2, subfamily C, polypeptide 19 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K17728  CYP4F8; cytochrome P450, family 4, subfamily F, polypeptide 8 [EC:1.14.14.1]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K08021  ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
       K08022  ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
       K17709  CYP2B6; cytochrome P450, family 2, subfamily B, polypeptide 6 [EC:1.14.13.-]
       K07412  CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K08726  EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
     00591 Linoleic acid metabolism [PATH:ko00591]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K14621  PLB1, PLB; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
       K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
       K16817  PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
       K01058  pldA; phospholipase A1 [EC:3.1.1.32 3.1.1.4]
       K15718  LOX1_5; linoleate 9S-lipoxygenase [EC:1.13.11.58]
       K00454  LOX2S; lipoxygenase [EC:1.13.11.12]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K00100  E1.1.1.-;  [EC:1.1.1.-]
       K17862  PPOC; linoleate 10R-lipoxygenase [EC:1.13.11.62]
       K17863  PPOA; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase [EC:1.13.11.60 5.4.4.5]
       K17864  LDS; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase [EC:1.13.11.60 5.4.4.6]
       K07409  CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K17721  CYP2C19; cytochrome P450, family 2, subfamily C, polypeptide 19 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K17689  CYP3A4; cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
       K07424  CYP3A; cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
       K00508  E1.14.19.3; linoleoyl-CoA desaturase [EC:1.14.19.3]
       K08262  E1.14.99.33; delta12-fatty acid dehydrogenase [EC:1.14.99.33]
     00592 alpha-Linolenic acid metabolism [PATH:ko00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ko01040]
     01004 Lipid biosynthesis proteins [BR:ko01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
     00730 Thiamine metabolism [PATH:ko00730]
     00740 Riboflavin metabolism [PATH:ko00740]
     00750 Vitamin B6 metabolism [PATH:ko00750]
     00760 Nicotinate and nicotinamide metabolism [PATH:ko00760]
     00770 Pantothenate and CoA biosynthesis [PATH:ko00770]
     00780 Biotin metabolism [PATH:ko00780]
     00785 Lipoic acid metabolism [PATH:ko00785]
     00790 Folate biosynthesis [PATH:ko00790]
     00670 One carbon pool by folate [PATH:ko00670]
     00830 Retinol metabolism [PATH:ko00830]
       K00515  BCMO1, BCDO1; beta-carotene 15,15'-monooxygenase [EC:1.14.99.36]
       K13951  ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
       K13980  ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
       K00121  frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
       K13952  ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
       K13953  adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
       K00001  E1.1.1.1, adh; alcohol dehydrogenase [EC:1.1.1.1]
       K11146  DHRS3; short-chain dehydrogenase/reductase 3 [EC:1.1.1.300]
       K11147  DHRS4; dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]
       K11148  DHRS4L2; dehydrogenase/reductase SDR family member 4-like protein 2 [EC:1.1.-.-]
       K11149  DHRS9; dehydrogenase/reductase SDR family member 9 [EC:1.1.-.-]
       K11150  RDH8; retinol dehydrogenase 8 [EC:1.1.1.-]
       K11151  RDH10; retinol dehydrogenase 10 [EC:1.1.1.-]
       K11152  RDH11; retinol dehydrogenase 11 [EC:1.1.1.300]
       K11153  RDH12; retinol dehydrogenase 12 [EC:1.1.1.300]
       K11154  RDH16; retinol dehydrogenase 16 [EC:1.1.1.-]
       K15734  SDR16C5; all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105]
       K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
       K00678  LRAT; phosphatidylcholine-retinol O-acyltransferase [EC:2.3.1.135]
       K11155  DGAT1; diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76]
       K11156  DGAT2L4, MFAT, AWAT2; diacylglycerol O-acyltransferase 2-like protein 4 [EC:2.3.1.75 2.3.1.76]
       K11157  PNPLA4; patatin-like phospholipase domain-containing protein 4 [EC:3.1.1.-]
       K11158  RPE65; retinoid isomerohydrolase [EC:3.1.1.64]
       K00061  RDH5; 11-cis-retinol dehydrogenase [EC:1.1.1.315]
       K00157  AOX; aldehyde oxidase [EC:1.2.3.1]
       K07249  E1.2.1.36; retinal dehydrogenase [EC:1.2.1.36]
       K07437  CYP26A; cytochrome P450, family 26, subfamily A
       K12664  CYP26B; cytochrome P450, family 26, subfamily B
       K12665  CYP26C; cytochrome P450, family 26, subfamily C
       K07408  CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
       K07409  CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
       K17683  CYP2A6; cytochrome P450, family 2, subfamily A, polypeptide 6 [EC:1.14.13.-]
       K07411  CYP2A; cytochrome P450, family 2, subfamily A [EC:1.14.14.1]
       K17709  CYP2B6; cytochrome P450, family 2, subfamily B, polypeptide 6 [EC:1.14.13.-]
       K07412  CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K17720  CYP2C18; cytochrome P450, family 2, subfamily C, polypeptide 18 [EC:1.14.14.1]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K07420  CYP2S1; cytochrome P450, family 2, subfamily S, polypeptide 1 [EC:1.14.14.1]
       K17689  CYP3A4; cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
       K17690  CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5 [EC:1.14.14.1]
       K17691  CYP3A7; cytochrome P450, family 3, subfamily A, polypeptide 7 [EC:1.14.14.1]
       K07424  CYP3A; cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
       K17687  CYP4A11; alkane 1-monooxygenase [EC:1.14.15.3]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K00699  UGT; glucuronosyltransferase [EC:2.4.1.17]
       K09516  RETSAT; all-trans-retinol 13,14-reductase [EC:1.3.99.23]
     00860 Porphyrin and chlorophyll metabolism [PATH:ko00860]
     00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:ko00130]
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
     04724 Glutamatergic synapse [PATH:ko04724]
     04727 GABAergic synapse [PATH:ko04727]
     04725 Cholinergic synapse [PATH:ko04725]
     04728 Dopaminergic synapse [PATH:ko04728]
     04726 Serotonergic synapse [PATH:ko04726]
       K00502  TPH1_2; tryptophan 5-monooxygenase [EC:1.14.16.4]
       K01593  DDC; aromatic-L-amino-acid decarboxylase [EC:4.1.1.28]
       K08155  SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K17718  CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K17720  CYP2C18; cytochrome P450, family 2, subfamily C, polypeptide 18 [EC:1.14.14.1]
       K17721  CYP2C19; cytochrome P450, family 2, subfamily C, polypeptide 19 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K17712  CYP2D6; cytochrome P450, family 2, subfamily D, polypeptide 6 [EC:1.14.14.1]
       K07414  CYP2D; cytochrome P450, family 2, subfamily D [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K07428  CYP4X; cytochrome P450, family 4, subfamily X [EC:1.14.14.1]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K08021  ALOX12B; arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-]
       K00460  ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
       K08022  ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04819  HTR3; 5-hydroxytryptamine receptor 3
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04163  HTR7; 5-hydroxytryptamine receptor 7
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04943  KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
       K04892  KCND2; potassium voltage-gated channel Shal-related subfamily D member 2
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04520  APP; amyloid beta A4 protein
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04161  HTR5; 5-hydroxytryptamine receptor 5
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K05037  SLC6A4; solute carrier family 6 (neurotransmitter transporter, serotonin) member 4
       K00274  MAO, aofH; monoamine oxidase [EC:1.4.3.4]
     04720 Long-term potentiation [PATH:ko04720]
     04730 Long-term depression [PATH:ko04730]
     04723 Retrograde endocannabinoid signaling [PATH:ko04723]
     04721 Synaptic vesicle cycle [PATH:ko04721]
     04722 Neurotrophin signaling pathway [PATH:ko04722]
 
   Sensory system
     04744 Phototransduction [PATH:ko04744]
     04745 Phototransduction - fly [PATH:ko04745]
     04740 Olfactory transduction [PATH:ko04740]
     04742 Taste transduction [PATH:ko04742]
     04750 Inflammatory mediator regulation of TRP channels [PATH:ko04750]
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04149  HRH1; histamine receptor H1
       K04269  P2RY2; purinergic receptor P2Y, G protein-coupled, 2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K04984  TRPA1, ANKTM1; transient receptor potential cation channel subfamily A member 1
       K05222  TRPV1; transient receptor potential cation channel subfamily V member 1
       K04829  ASIC1, ACCN2, BNAC2; acid-sensing ion channel 1
       K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
       K04830  ASIC3, ACCN3; acid-sensing ion channel 3
       K04831  ASIC4, ACCN4, BNAC4; acid-sensing ion channel 4
       K04832  ASIC5, ACCN5; acid-sensing ion channel 5
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04983  TRPM8; transient receptor potential cation channel subfamily M member 8
       K04259  PTGER2; prostaglandin E receptor 2
       K04261  PTGER4; prostaglandin E receptor 4
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04973  TRPV4; transient receptor potential cation channel subfamily V member 4
       K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05459  IGF1; insulin-like growth factor 1
       K04971  TRPV2; transient receptor potential cation channel subfamily V member 2
       K04972  TRPV3; transient receptor potential cation channel subfamily V member 3
 
   Development
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
       K07408  CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
       K17689  CYP3A4; cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-]
       K17690  CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5 [EC:1.14.14.1]
       K17691  CYP3A7; cytochrome P450, family 3, subfamily A, polypeptide 7 [EC:1.14.14.1]
       K17692  CYP3A43; cytochrome P450, family 3, subfamily A, polypeptide 43 [EC:1.14.14.1]
       K07424  CYP3A; cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K00622  nat; arylamine N-acetyltransferase [EC:2.3.1.5]
       K07409  CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2 [EC:1.14.14.1]
       K01014  SULT1A; aryl sulfotransferase [EC:2.8.2.1]
       K07410  CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
       K17718  CYP2C8; cytochrome P450, family 2, subfamily C, polypeptide 8 [EC:1.14.14.1]
       K17719  CYP2C9; cytochrome P450, family 2, subfamily C, polypeptide 9 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K17720  CYP2C18; cytochrome P450, family 2, subfamily C, polypeptide 18 [EC:1.14.14.1]
       K17721  CYP2C19; cytochrome P450, family 2, subfamily C, polypeptide 19 [EC:1.14.13.48 1.14.13.49 1.14.13.80 1.14.13.-]
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K01253  EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K00799  GST, gst; glutathione S-transferase [EC:2.5.1.18]
       K13299  GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
       K11822  SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
       K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
       K00079  CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
       K15680  HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
       K17683  CYP2A6; cytochrome P450, family 2, subfamily A, polypeptide 6 [EC:1.14.13.-]
       K17685  CYP2A13; cytochrome P450, family 2, subfamily A, polypeptide 13 [EC:1.14.14.1]
       K00699  UGT; glucuronosyltransferase [EC:2.4.1.17]
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K07412  CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
       K00129  E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
       K13951  ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
       K13980  ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
       K13952  ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
       K00121  frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
       K00816  CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: December 24, 2014