 Metabolism
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Genetic Information Processing
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Environmental Information Processing
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Cellular Processes
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 Organismal Systems
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Immune system
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04640 Hematopoietic cell lineage [PATH:ko04640]
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04610 Complement and coagulation cascades [PATH:ko04610]
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04620 Toll-like receptor signaling pathway [PATH:ko04620]
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04621 NOD-like receptor signaling pathway [PATH:ko04621]
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04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
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04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
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04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
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 K06751 MHC1; major histocompatibility complex, class I
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL; killer cell immunoglobulin-like receptor 2DL
K06541 KLRC; killer cell lectin-like receptor subfamily C
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D, member 1
K05697 PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1; intercellular adhesion molecule 1
K06523 ICAM2; intercellular adhesion molecule 2
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K03156 TNFA; tumor necrosis factor superfamily, member 2
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K06742 NCR2; natural cytotoxicity triggering receptor 2
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
K06741 NCR1; natural cytotoxicity triggering receptor 1
K06743 NCR3; natural cytotoxicity triggering receptor 3
K07983 FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC; src homology 2 domain-containing transforming protein C
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K07987 RAET1; retinoic acid early transcript 1
K06728 KLRK1; killer cell lectin-like receptor subfamily K, member 1
K07988 HCST, DAP10; hematopoietic cell signal transducer
K06479 CD48, BCM1; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K04446 NFATC, NFAT; nuclear factor of activated T-cells, cytoplasmic
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K07989 EAT2; EWS/FLI1 activated transcript 2
K07990 SH2D1A, SAP; SH2 domain protein 1A
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
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04612 Antigen processing and presentation [PATH:ko04612]
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04660 T cell receptor signaling pathway [PATH:ko04660]
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04662 B cell receptor signaling pathway [PATH:ko04662]
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04664 Fc epsilon RI signaling pathway [PATH:ko04664]
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04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
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04670 Leukocyte transendothelial migration [PATH:ko04670]
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04672 Intestinal immune network for IgA production [PATH:ko04672]
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04062 Chemokine signaling pathway [PATH:ko04062]
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Endocrine system
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Circulatory system
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Digestive system
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Excretory system
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Nervous system
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Sensory system
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Development
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Environmental adaptation
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Human Diseases
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Cancers
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Immune diseases
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05310 Asthma [PATH:ko05310]
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05322 Systemic lupus erythematosus [PATH:ko05322]
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05323 Rheumatoid arthritis [PATH:ko05323]
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05320 Autoimmune thyroid disease [PATH:ko05320]
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K05414 IFNA; interferon alpha
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K10809 TG; thyroglobulin
K06752 MHC2; major histocompatibility complex, class II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K06751 MHC1; major histocompatibility complex, class I
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
K04249 TSHR; thyroid stimulating hormone receptor
K08522 CGA; glycoprotein hormones, alpha polypeptide
K05251 TSHB; thyroid stimulating hormone, beta
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05330 Allograft rejection [PATH:ko05330]
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K06751 MHC1; major histocompatibility complex, class I
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K06752 MHC2; major histocompatibility complex, class II
K05429 IL2; interleukin 2
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K04687 IFNG; interferon gamma
K03156 TNFA; tumor necrosis factor superfamily, member 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
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05332 Graft-versus-host disease [PATH:ko05332]
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K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K03156 TNFA; tumor necrosis factor superfamily, member 2
K06752 MHC2; major histocompatibility complex, class II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K06751 MHC1; major histocompatibility complex, class I
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K04687 IFNG; interferon gamma
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D, member 1
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05340 Primary immunodeficiency [PATH:ko05340]
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Neurodegenerative diseases
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Substance dependence
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Cardiovascular diseases
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05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
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05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
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05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
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05416 Viral myocarditis [PATH:ko05416]
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K06788 CXADR, CAR; coxsackievirus and adenovirus receptor
K04006 DAF, CD55; decay accelerating factor
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06278 CAV1; caveolin 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K12563 SGCD; delta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K06265 DAG1; dystroglycan 1
K10366 DMD; dystrophin
K05692 ACTB_G1; actin beta/gamma 1
K03260 EIF4G; translation initiation factor 4G
K04503 CCND1; cyclin D1
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10352 MYH; myosin heavy chain
K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K06752 MHC2; major histocompatibility complex, class II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06751 MHC1; major histocompatibility complex, class I
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K07818 PRF1; perforin 1
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06490 ICAM1; intercellular adhesion molecule 1
K06856 IGH; immunoglobulin heavy chain
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Endocrine and metabolic diseases
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04940 Type I diabetes mellitus [PATH:ko04940]
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K04526 INS; insulin
K01580 E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
K07817 PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
K01294 CPE; carboxypeptidase E [EC:3.4.17.10]
K04077 groEL, HSPD1; chaperonin GroEL
K06752 MHC2; major histocompatibility complex, class II
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05429 IL2; interleukin 2
K04687 IFNG; interferon gamma
K06751 MHC1; major histocompatibility complex, class I
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04389 TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03156 TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
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04930 Type II diabetes mellitus [PATH:ko04930]
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04950 Maturity onset diabetes of the young [PATH:ko04950]
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Infectious diseases
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KEGG Orthology (KO)