KEGG Orthology (KO)

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 Metabolism
 
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   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
     00230 Purine metabolism [PATH:ko00230]
       K13988  NUDT9; ADP-ribose pyrophosphatase [EC:3.6.1.13]
       K01515  nudF; ADP-ribose pyrophosphatase [EC:3.6.1.13]
       K01517  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
       K13987  NUDT5; ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase [EC:3.6.1.13 3.6.1.58 3.6.1.-]
       K08312  nudE; ADP-ribose diphosphatase [EC:3.6.1.-]
       K18447  NUDX14; ADP-sugar diphosphatase [EC:3.6.1.21]
       K01839  deoB; phosphopentomutase [EC:5.4.2.7]
       K01835  pgm; phosphoglucomutase [EC:5.4.2.2]
       K15778  pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
       K15779  PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
       K00948  PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
       K00764  purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
       K11787  GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
       K11788  ADE5; phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
       K01945  purD; phosphoribosylamine--glycine ligase [EC:6.3.4.13]
       K13713  purCD; fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
       K00601  E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
       K11175  purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
       K08289  purT; phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2]
       K01952  purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
       K01933  purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
       K01587  PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
       K11808  ADE2; phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21]
       K01589  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
       K01588  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
       K01923  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
       K01756  purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]
       K00602  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
       K01492  E2.1.2.3; phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.3]
       K06863  purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
       K11176  purO; IMP cyclohydrolase [EC:3.5.4.10]
       K00759  APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]
       K01081  E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
       K11751  ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
       K03787  surE; 5'-nucleotidase [EC:3.1.3.5]
       K08722  yfbR; 5'-nucleotidase [EC:3.1.3.5]
       K08723  yjjG; 5'-nucleotidase [EC:3.1.3.5]
       K00892  gsk; inosine kinase [EC:2.7.1.73]
       K03783  punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K03784  deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
       K03815  xapA; xanthosine phosphorylase [EC:2.4.2.-]
       K01239  iunH; purine nucleosidase [EC:3.2.2.1]
       K10213  rihB; ribosylpyrimidine nucleosidase [EC:3.2.2.8]
       K00760  hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
       K15780  tilS-hprT; bifunctional protein TilS/HprT [EC:6.3.4.19 2.4.2.8]
       K00088  guaB; IMP dehydrogenase [EC:1.1.1.205]
       K00940  E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
       K01510  ENTPD1_3_8; apyrase [EC:3.6.1.5]
       K14641  APY1_2; apyrase [EC:3.6.1.5]
       K14642  YND1; golgi apyrase [EC:3.6.1.5]
       K12304  CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
       K12305  ENTPD4, LALP70; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
       K01511  ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
       K16855  NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
       K01519  ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.19]
       K02428  rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
       K04765  mazG; ATP diphosphatase [EC:3.6.1.8]
       K00769  gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
       K03816  xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
       K00106  XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
       K00087  ygeS, xdhA; xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4]
       K13479  ygeT, xdhB; xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4]
       K13480  ygeU, xdhC; xanthine dehydrogenase iron-sulfur-binding subunit
       K13481  xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]
       K13482  xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]
       K11177  yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
       K11178  yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
       K13483  yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
       K01518  E3.6.1.17; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
       K18445  ndx1; diadenosine hexaphosphate hydrolase (ATP-forming) [EC:3.6.1.61]
       K01951  guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
       K00364  E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]
       K01487  E3.5.4.3, guaD; guanine deaminase [EC:3.5.4.3]
       K00942  E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]
       K00873  PK, pyk; pyruvate kinase [EC:2.7.1.40]
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K00524  nrdJ; ribonucleotide reductase, class II [EC:1.17.4.1]
       K00525  E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
       K00526  E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
       K10807  RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
       K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
       K00527  nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2]
       K00904  DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
       K15518  dgk; deoxyguanosine kinase [EC:2.7.1.113]
       K01129  dgt; dGTPase [EC:3.1.5.1]
       K03040  rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
       K03043  rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
       K03046  rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
       K13797  rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
       K03048  rpoE; DNA-directed RNA polymerase subunit delta
       K03060  rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
       K03042  rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
       K03041  rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
       K03044  rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
       K03045  rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
       K13798  K13798, rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
       K03053  rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
       K03055  rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
       K03058  rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
       K03047  rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
       K03049  rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
       K03050  rpoE2; DNA-directed RNA polymerase subunit E" [EC:2.7.7.6]
       K03056  rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
       K03059  rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
       K03051  rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
       K03052  rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
       K03054  rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
       K02999  RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
       K03002  RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
       K03000  RPA12, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
       K03001  RPA14; DNA-directed RNA polymerase I subunit RPA14
       K03003  RPA34; DNA-directed RNA polymerase I subunit RPA34
       K03004  RPA43; DNA-directed RNA polymerase I subunit RPA43
       K03005  RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K03018  RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
       K03021  RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
       K03023  RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
       K03026  RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
       K14721  RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
       K03027  RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
       K03019  RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
       K03020  RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
       K03022  RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
       K03024  RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
       K03025  RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
       K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
       K02319  DPA, polB1; DNA polymerase I [EC:2.7.7.7]
       K02322  DPB1; DNA polymerase II large subunit [EC:2.7.7.7]
       K02323  DPB2; DNA polymerase II small subunit [EC:2.7.7.7]
       K02337  DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
       K03763  DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
       K02338  DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
       K02343  DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
       K02340  DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
       K02341  DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
       K02342  DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
       K14159  rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
       K02345  DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
       K02339  DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
       K02344  DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
       K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
       K02321  POLA2; DNA polymerase alpha subunit B
       K02684  PRI1; DNA primase small subunit [EC:2.7.7.-]
       K02685  PRI2; DNA primase large subunit [EC:2.7.7.-]
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K01139  spoT, HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
       K01514  PPX1; exopolyphosphatase [EC:3.6.1.11]
       K01524  ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
       K00951  relA; GTP pyrophosphokinase [EC:2.7.6.5]
       K07816  E2.7.6.5X; putative GTP pyrophosphokinase [EC:2.7.6.5]
       K01768  E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
       K05851  E4.6.1.1A, cyaA; adenylate cyclase, class 1 [EC:4.6.1.1]
       K05873  E4.6.1.1B, cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K11265  ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
       K11029  cyaA; anthrax edema toxin adenylate cyclase [EC:4.6.1.1]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12320  GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
       K12321  GUCY2D_E_F; guanylate cyclase 2D/E/F [EC:4.6.1.2]
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K01769  E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
       K01120  cpdP; 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17]
       K13755  PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13762  PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
       K08718  PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
       K13756  PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
       K13757  PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
       K13758  PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
       K13759  PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
       K13760  PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
       K13763  PDE6N; cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35]
       K13761  PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
       K18438  PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
       K13298  PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
       K01939  purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]
       K01490  AMPD; AMP deaminase [EC:3.5.4.6]
       K00856  E2.7.1.20, ADK; adenosine kinase [EC:2.7.1.20]
       K00893  DCK; deoxycitidine kinase [EC:2.7.1.74]
       K15519  dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]
       K01488  add, ADA; adenosine deaminase [EC:3.5.4.4]
       K01241  amn; AMP nucleosidase [EC:3.2.2.4]
       K01486  ade; adenine deaminase [EC:3.5.4.2]
       K01119  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
       K08693  E3.1.3.6; 3'-nucleotidase [EC:3.1.3.6]
       K00939  E2.7.4.3, adk; adenylate kinase [EC:2.7.4.3]
       K01509  ENTPD2; adenosinetriphosphatase [EC:3.6.1.3]
       K06928  NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
       K10353  E2.7.1.76, dak; deoxyadenosine kinase [EC:2.7.1.76]
       K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
       K13293  PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
       K18436  PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
       K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
       K13294  PDEB2, PDE2B; cAMP-specific phosphodiesterase [EC:3.1.4.53]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K18424  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
       K00988  APA1_2; ATP adenylyltransferase [EC:2.7.7.53]
       K01525  apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]
       K13811  PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
       K00955  cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
       K00860  cysC; adenylylsulfate kinase [EC:2.7.1.25]
       K01513  ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
       K00956  cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
       K00957  cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
       K00958  sat, met3; sulfate adenylyltransferase [EC:2.7.7.4]
       K00365  uaZ; urate oxidase [EC:1.7.3.3]
       K16838  pucL; urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:1.7.3.3 4.1.1.97]
       K16839  hpxO; FAD-dependent urate hydroxylase [EC:1.14.13.113]
       K07127  uraH, pucM, hiuH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]
       K13484  TTHL; 5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.97]
       K13485  PRHOXNB, URAD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
       K16840  hpxQ; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
       K16841  hpxA; allantoin racemase [EC:5.1.99.3]
       K01466  allB; allantoinase [EC:3.5.2.5]
       K16842  hpxB; allantoinase [EC:3.5.2.5]
       K01477  alc, ALLC; allantoicase [EC:3.5.3.4]
       K02083  allC; allantoate deiminase [EC:3.5.3.9]
       K14977  ylbA, UGHY; (S)-ureidoglycine aminohydrolase [EC:3.5.3.26]
       K18151  UAH; ureidoglycolate amidohydrolase [EC:3.5.1.116]
       K01483  allA; ureidoglycolate lyase [EC:4.3.2.3]
       K16856  ugl; ureidoglycolate lyase [EC:4.3.2.3]
       K01427  URE; urease [EC:3.5.1.5]
       K01428  ureC; urease subunit alpha [EC:3.5.1.5]
       K01429  ureB; urease subunit beta [EC:3.5.1.5]
       K01430  ureA; urease subunit gamma [EC:3.5.1.5]
       K14048  ureAB; urease subunit gamma/beta [EC:3.5.1.5]
       K00073  allD; ureidoglycolate dehydrogenase (NAD+) [EC:1.1.1.350]
       K00926  arcC; carbamate kinase [EC:2.7.2.2]
     00240 Pyrimidine metabolism [PATH:ko00240]
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K07831  MRAS; Ras-related protein M-Ras
       K08019  RAPGEF5; Rap guanine nucleotide exchange factor 5
       K17697  DOCK4; dedicator of cytokinesis protein 4
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K02183  CALM; calmodulin
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04172  FPR1; formyl peptide receptor 1
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04357  EGF; epidermal growth factor
       K04358  FGF; fibroblast growth factor
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K05453  CSF1, MCSF; macrophage colony-stimulating factor 1
       K05461  KITLG; KIT ligand
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K05460  HGF; hepatocyte growth factor
       K05465  ANGPT1; angiopoietin 1
       K05466  ANGPT2; angiopoietin 2
       K05467  ANGPT4; angiopoietin 4
       K05462  EFNA; ephrin-A
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K05098  KDR, VEGFR2; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K05121  TEK, TIE2; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K06277  RAPGEF1, GRF2; Rap guanine nucleotide exchange factor 1
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05631  AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
       K05629  AIP1; atrophin-1 interacting protein 1
       K06112  MAGI3; membrane-associated guanylate kinase-related
       K08018  RAPGEF2, PDZGEF1; Rap guanine nucleotide exchange factor 2
       K08020  RAPGEF6, PDZGEF2; Rap guanine nucleotide exchange factor 6
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K07362  LAT; linker for activation of T cells
       K17698  FYB, ADAP; FYN binding protein
       K07361  LCP2; lymphocyte cytosolic protein 2
       K17699  SKAP1, SKAP55; src kinase associated phosphoprotein 1
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K06070  PKD; protein kinase D [EC:2.7.11.13]
       K04145  DRD2; dopamine receptor D2
       K04277  CNR1; cannabinoid receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K17700  RAP1GAP, RAPGAP; RAP1 GTPase activating protein 1
       K17701  SIPA1L1, E6TP1; signal-induced proliferation-associated 1 like protein 1
       K08013  SIPA1; signal-induced proliferation-associated gene 1
       K17702  SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like protein 2
       K17703  SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like protein 3
       K04680  ID1; DNA-binding protein inhibitor ID1
       K16857  THBS1; thrombospondin 1
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K17704  APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
       K06271  TLN; talin
       K06476  ITGA2B; integrin alpha 2B
       K06493  ITGB3; integrin beta 3
       K05759  PFN; profilin
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05692  ACTB_G1; actin beta/gamma 1
       K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
       K04513  RHOA; Ras homolog gene family, member A
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06082  FARP2, FRG; FERM, RhoGEF and pleckstrin domain protein 2
       K04393  CDC42; cell division control protein 42
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K04237  PARD3; partitioning defective protein 3
       K06093  PARD6; partitioning defective protein 6
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K05702  AF6, MLLT4; afadin
       K05690  CTNND1; catenin (cadherin-associated protein), delta 1
       K17705  KRIT1; Krev interaction trapped protein 1
       K17706  RGS14; regulator of G-protein signaling 14
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K05718  ITGAL; integrin alpha L
       K06461  ITGAM; integrin alpha M
       K06464  ITGB2; integrin beta 2
       K05719  ITGB1; integrin beta 1
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04024 cAMP signaling pathway [PATH:ko04024]
       K05250  FSH; follicle stimulating hormone
       K04141  ADRB1; adrenergic receptor beta-1
       K04144  DRD1; dopamine receptor D1
       K05840  DRD5; dopamine receptor D5
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04259  PTGER2; prostaglandin E receptor 2
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K04590  VIPR2; vasoactive intestinal peptide receptor 2
       K04249  TSHR; thyroid stimulating hormone receptor
       K04200  MC2R; melanocortin 2 receptor
       K04581  GLP1R; glucagon-like peptide 1 receptor
       K04580  GIPR; gastric inhibitory polypeptide receptor
       K08424  GPR119; G protein-coupled receptor 119
       K04247  FSHR; follicle stimulating hormone receptor
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K05232  NPY; neuropeptide Y
       K05254  GHRL; ghrelin
       K04142  ADRB2; adrenergic receptor beta-2
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04145  DRD2; dopamine receptor D2
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04265  ADORA1; adenosine A1 receptor
       K04197  EDNRA; endothelin receptor type A
       K04204  NPY1R; neuropeptide Y receptor type 1
       K04217  SSTR1; somatostatin receptor 1
       K04218  SSTR2; somatostatin receptor 2
       K04221  SSTR5; somatostatin receptor 5
       K08401  GPR81; G protein-coupled receptor 81
       K08402  GPR109; G protein-coupled receptor 109
       K04328  FFAR2, GPR43; free fatty acid receptor 2
       K10042  SUCNR1, GPR91; succinate receptor 1
       K04260  PTGER3; prostaglandin E receptor 3
       K04229  OXTR; oxytocin receptor
       K04284  GHSR; growth hormone secretagogue receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K11265  ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
       K04955  HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2
       K04957  HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4
       K04948  CNGA1; cyclic nucleotide gated channel alpha 1
       K04949  CNGA2; cyclic nucleotide gated channel alpha 2
       K04950  CNGA3; cyclic nucleotide gated channel alpha 3
       K04951  CNGA4; cyclic nucleotide gated channel alpha 4
       K04952  CNGB1; cyclic nucleotide gated channel beta 1
       K04953  CNGB3; cyclic nucleotide gated channel beta 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K05673  ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
       K04513  RHOA; Ras homolog gene family, member A
       K05702  AF6, MLLT4; afadin
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K15494  PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04355  BDNF; brain-derived neurotrophic factor
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K06230  GLI3; zinc finger protein GLI3
       K16797  GLI1; zinc finger protein GLI1
       K06225  PTCH1; patched 1
       K06231  HHIP; hedgehog interacting protein
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K18435  SOX9; transcription factor SOX9 (SOX group E)
       K04665  AMH; anti-mullerian hormone
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K02158  BAD; BCL2-antagonist of cell death
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12755  MYL9; myosin regulatory light chain 9
       K12044  TNNI3; troponin I, cardiac muscle
       K05852  PLN; phospholamban
       K04962  RYR2; ryanodine receptor 2
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K13360  FXYD1, PLM; FXYD domain-containing ion transport regulator 1
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13293  PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
       K04166  AGTR1; angiotensin II receptor type 1
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04138  ADRA2A; adrenergic receptor alpha-2A
       K04139  ADRA2B; adrenergic receptor alpha-2B
       K04140  ADRA2C; adrenergic receptor alpha-2C
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K04969  TRPC6; transient receptor potential cation channel subfamily C member 6
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K09260  MEF2A; MADS-box transcription enhancer factor 2A
       K09261  MEF2B; MADS-box transcription enhancer factor 2B
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K09262  MEF2D; MADS-box transcription enhancer factor 2D
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K04378  SRF; serum response factor
       K09183  GATA4; GATA-binding protein 4
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K05849  SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K18154  RGS2; regulator of G-protein signaling 2
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K05852  PLN; phospholamban
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12755  MYL9; myosin regulatory light chain 9
       K04948  CNGA1; cyclic nucleotide gated channel alpha 1
       K04952  CNGB1; cyclic nucleotide gated channel beta 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13762  PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K03916  BDKRB2; bradykinin receptor B2
       K04213  OPRD1; delta-type opioid receptor
       K04265  ADORA1; adenosine A1 receptor
       K04268  ADORA3; adenosine A3 receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K05001  KCNJ8; potassium inwardly-rectifying channel subfamily J member 8
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K02158  BAD; BCL2-antagonist of cell death
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K08556  NR3C3, PGR; progesterone receptor
       K08557  NR3C4, AR; androgen receptor
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K11481  AURKA; aurora kinase A [EC:2.7.11.1]
       K02602  ORB; oo18 RNA-binding protein
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K06630  YWHAE; 14-3-3 protein epsilon
       K16198  YWHAG_H; 14-3-3 protein gamma/eta
       K08694  SPDY, RINGO; speedy
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K08836  SLK; STE20-like kinase [EC:2.7.11.1]
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K13056  C3H-4; CCCH zinc finger protein C3H-4
       K03868  RBX1, ROC1; RING-box protein 1
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K10292  FBXO5, EMI1; F-box protein 5
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K10318  FBXO43, EMI2; F-box protein 43
       K06635  PTTG; securin
       K02365  ESP1; separase [EC:3.4.22.49]
       K13054  REC8L; meiotic recombination protein REC8, animal type
       K13055  STAG3; cohesin complex subunit SA-3
       K06636  SMC1; structural maintenance of chromosome 1
       K06669  SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K06626  CCNE; cyclin E
       K11580  SGOL1; shugoshin-like 1
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
     04210 Apoptosis [PATH:ko04210]
     04115 p53 signaling pathway [PATH:ko04115]
 
   Cell communication
     04510 Focal adhesion [PATH:ko04510]
     04520 Adherens junction [PATH:ko04520]
     04530 Tight junction [PATH:ko04530]
     04540 Gap junction [PATH:ko04540]
       K07372  GJA1, CX43; gap junction protein, alpha 1
       K07373  GJD2; gap junction delta-2 protein
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K05450  PDGFC_D; platelet derived growth factor C/D
       K04357  EGF; epidermal growth factor
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K07374  TUBA; tubulin alpha
       K07375  TUBB; tubulin beta
       K08959  CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K05701  TJP1, ZO1; tight junction protein 1
       K04141  ADRB1; adrenergic receptor beta-1
       K04144  DRD1; dopamine receptor D1
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K04145  DRD2; dopamine receptor D2
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
 
 Organismal Systems
 
   Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
       K04264  TBXA2R; thromboxane A2 receptor
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12757  MYL12; myosin regulatory light chain 12
       K05215  P2RX1; P2X purinoceptor 1
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K16059  STIM1; stromal interaction molecule 1
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K04270  P2RY1; purinergic receptor P2Y, G protein-coupled, 1
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K06069  APKC; atypical protein kinase C [EC:2.7.11.13]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K17704  APBB1IP, RIAM; amyloid beta A4 precursor protein-binding family B member 1-interacting protein
       K06271  TLN; talin
       K06476  ITGA2B; integrin alpha 2B
       K06493  ITGB3; integrin beta 3
       K17084  FERMT3, KIND3; kindlin 3
       K03903  FGA; fibrinogen alpha chain
       K03904  FGB; fibrinogen beta chain
       K03905  FGG; fibrinogen gamma chain
       K04298  P2RY12; purinergic receptor P2Y, G protein-coupled, 12
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04263  PTGIR; prostacyclin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06274  VASP; vasodilator-stimulated phosphoprotein
       K05692  ACTB_G1; actin beta/gamma 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05732  GRLF1; glucocorticoid receptor DNA-binding factor 1
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K06236  COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
       K06264  GP6; platelet glycoprotein VI
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06481  ITGA2; integrin alpha 2
       K05719  ITGB1; integrin beta 1
       K07361  LCP2; lymphocyte cytosolic protein 2
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
       K03900  VWF; von Willebrand factor
       K06260  GP5; platelet glycoprotein V
       K06261  GP1BA; platelet glycoprotein Ib alpha chain
       K06262  GP1BB; platelet glycoprotein Ib beta chain
       K06263  GP9; platelet glycoprotein IX
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00509  PTGS1, COX1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
       K01832  TBXAS1, CYP5A; thromboxane-A synthase [EC:5.3.99.5]
       K08508  SNAP23; synaptosomal-associated protein 23
       K08512  VAMP8; vesicle-associated membrane protein 8
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04662 B cell receptor signaling pathway [PATH:ko04662]
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K10029  PPBP, CXCL7; platelet basic protein
       K10030  IL8, CXCL8; interleukin 8
       K05416  CXCL9; C-X-C motif chemokine 9
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K12672  CXCL11, I-TAC; C-X-C motif chemokine 11
       K10031  CXCL12; C-X-C motif chemokine 12
       K10032  CXCL13; C-X-C motif chemokine 13
       K10035  CXCL16; C-X-C motif chemokine 16
       K10034  CXCL15; C-X-C motif chemokine 15
       K05407  PF4, CXCL4; platelet factor 4
       K10033  CXCL14, SCYB14; C-X-C motif chemokine 14
       K05507  XCL, SCM1; C motif chemokine 1/2
       K05508  CX3CL1, NTT; C-X3-C motif chemokine 1
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K05408  CCL3; C-C motif chemokine 3
       K12964  CCL4; C-C motif chemokine 4
       K12499  CCL5; C-C motif chemokine 5
       K05510  CCL6_9; C-C motif chemokine 6/9
       K05509  CCL7; C-C motif chemokine 7
       K16596  CCL8; C-C motif chemokine 8
       K16597  CCL11; C-C motif chemokine 11
       K16595  CCL13; C-C motif chemokine 13
       K05511  CCL15_23; C-C motif chemokine 15/23
       K05512  CCL19, ELC; C-C motif chemokine 19
       K14625  CCL20; C-C motif chemokine 20
       K16062  CCL21, SLC; C-C motif chemokine 21
       K13072  CCL25; C-C motif chemokine 25
       K16598  CCL27; C-C motif chemokine 27
       K05513  CCL28; C-C motif chemokine 28
       K05514  CCLX; C-C motif chemokine, other
       K05050  IL8RB, CXCR2; interleukin 8 receptor beta
       K04175  IL8RA, CXCR1; interleukin 8 receptor alpha
       K04188  CXCR3, GPR9; C-X-C chemokine receptor type 3
       K04189  CXCR4; C-X-C chemokine receptor type 4
       K04190  CXCR5, BLR1; C-X-C chemokine receptor type 5
       K04191  CXCR6; C-X-C chemokine receptor type 6
       K04193  XCR1; XC chemokine receptor 1
       K04192  CX3CR1; CX3C chemokine receptor 1
       K04183  CCR8; C-C chemokine receptor type 8
       K04181  CCR6; C-C chemokine receptor type 6
       K04184  CCR9; C-C chemokine receptor type 9
       K04179  CCR4; C-C chemokine receptor type 4
       K04182  CCR7; C-C chemokine receptor type 7
       K04177  CCR2; C-C chemokine receptor type 2
       K04180  CCR5; C-C chemokine receptor type 5
       K04176  CCR1; C-C chemokine receptor type 1
       K04178  CCR3; C-C chemokine receptor type 3
       K04185  CCR10; C-C chemokine receptor type 10
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04692  STAT3; signal transducer and activator of transcription 3
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]
       K08891  FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K09408  FOXO3; forkhead box protein O3
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K07363  ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04393  CDC42; cell division control protein 42
       K05747  WAS; Wiskott-Aldrich syndrome protein
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K12365  PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
       K12366  ELMO1, CED12; engulfment and cell motility protein 1
       K12367  DOCK2; dedicator of cytokinesis protein 2
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K05760  PXN; paxillin
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K04438  CRK, CRKII; proto-oncogene C-crk
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04237  PARD3; partitioning defective protein 3
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
       K00909  GRK1_7; rhodopsin kinase [EC:2.7.11.14]
       K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
       K08291  GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
       K04439  ARRB; beta-arrestin
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
       K12407  GCK; glucokinase [EC:2.7.1.2]
       K04979  TRPM4; transient receptor potential cation channel subfamily M member 4
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05032  ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8
       K05004  KCNJ11; potassium inwardly-rectifying channel subfamily J member 11
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K04942  KCNN1; potassium intermediate/small conductance calcium-activated channel subfamily N member 1
       K04943  KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
       K04944  KCNN3; potassium intermediate/small conductance calcium-activated channel subfamily N member 3
       K04945  KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
       K05325  KCNNN; potassium intermediate/small conductance calcium-activated channel subfamily N, invertebrate
       K05259  GCG; glucagon
       K04581  GLP1R; glucagon-like peptide 1 receptor
       K05258  GIP; gastric inhibitory polypeptide
       K08424  GPR119; G protein-coupled receptor 119
       K05262  ADCYAP; adenylate cyclase activating polypeptide
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K07594  IPF1, PDX1; insulin promoter factor 1
       K04526  INS; insulin
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K15297  RIMS2, RIM2; regulating synaptic membrane exocytosis protein 2
       K16882  PCLO; protein piccolo
       K07882  RAB3A; Ras-related protein Rab-3A
       K04194  CCKAR; cholecystokinin A receptor
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04325  FFAR1, GPR40; free fatty acid receptor 1
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04962  RYR2; ryanodine receptor 2
       K13504  VAMP2; vesicle-associated membrane protein 2
       K04560  STX1A; syntaxin 1A
       K18211  SNAP25; synaptosomal-associated protein 25
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
     03320 PPAR signaling pathway [PATH:ko03320]
     04912 GnRH signaling pathway [PATH:ko04912]
       K05252  GNRH; gonadotropin-releasing hormone
       K04280  GNRHR; gonadotropin-releasing hormone receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04393  CDC42; cell division control protein 42
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K08521  LHB; luteinizing hormone beta polypeptide
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K05250  FSH; follicle stimulating hormone
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K07763  MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04375  ELK1; ETS domain-containing protein Elk-1
     04913 Ovarian Steroidogenesis [PATH:ko04913]
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K08521  LHB; luteinizing hormone beta polypeptide
       K04248  LHCGR; luteinizing hormone/choriogonadotropin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K12473  LDLR; low-density lipoprotein receptor
       K13885  SCARB1; scavenger receptor class B, member 1
       K16931  STAR; steroidogenic acute regulatory protein, mitochondrial
       K00498  CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
       K00512  CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.99.9 4.1.2.30]
       K00044  HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
       K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
       K04119  AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.64 1.1.1.188 1.1.1.213]
       K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
       K00070  HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
       K05250  FSH; follicle stimulating hormone
       K04247  FSHR; follicle stimulating hormone receptor
       K07434  CYP19A; aromatase [EC:1.14.14.14]
       K07410  CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
       K07408  CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
       K05498  GDF9_9B; growth differentiation factor 9/9B
       K16620  BMP6; bone morphogenetic protein 6
     04915 Estrogen signaling pathway [PATH:ko04915]
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K08551  NR3A2, ESR2; estrogen receptor beta
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K09571  FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K04684  SP1; transcription factor Sp1
       K04246  GPR30; G protein-coupled receptor 30
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06279  SHC1; SHC- transforming protein 1
       K17447  SHC2; SHC- transforming protein 2
       K17448  SHC3; SHC- transforming protein 3
       K17449  SHC4; SHC- transforming protein 4
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04215  OPRM1; mu-type opioid receptor
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K04603  GRM1; metabotropic glutamate receptor 1
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
       K08556  NR3C3, PGR; progesterone receptor
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02602  ORB; oo18 RNA-binding protein
       K08694  SPDY, RINGO; speedy
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K06627  CCNA; cyclin A
       K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04373  RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
       K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
       K05868  CCNB; cyclin B
       K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]
       K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
       K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
       K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
       K04526  INS; insulin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K07827  KRAS, KRAS2; GTPase KRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
       K06638  MAD1L; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K13728  MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       K03364  CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12456  APC13; anaphase-promoting complex subunit 13
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
       K05243  OXT; oxytocin-neurophysin 1
       K04229  OXTR; oxytocin receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
       K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K04503  CCND1; cyclin D1
       K04375  ELK1; ETS domain-containing protein Elk-1
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K04977  TRPM2; transient receptor potential cation channel subfamily M member 2
       K04996  KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
       K05005  KCNJ12; potassium inwardly-rectifying channel subfamily J member 12
       K04998  KCNJ4; potassium inwardly-rectifying channel subfamily J member 4
       K05007  KCNJ14; potassium inwardly-rectifying channel subfamily J member 14
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
       K03234  EEF2; elongation factor 2
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K18154  RGS2; regulator of G-protein signaling 2
       K17901  RCAN1, MCIP1; calcipressin-1
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K08794  CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K13242  NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
     04918 Thyroid hormone synthesis [PATH:ko04918]
       K05251  TSHB; thyroid stimulating hormone, beta
       K08522  CGA; glycoprotein hormones, alpha polypeptide
       K04249  TSHR; thyroid stimulating hormone receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K15225  TTF1; transcription termination factor 1
       K15173  TTF2; transcription termination factor 2 [EC:3.6.4.-]
       K09293  PAX8; paired box protein 8
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K10809  TG; thyroglobulin
       K09490  HSPA5, BIP; heat shock 70kDa protein 5
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K08054  CANX; calnexin
       K09582  PDIA4, ERP72; protein disulfide-isomerase A4 [EC:5.3.4.1]
       K10063  ASGR1; asialoglycoprotein receptor 1
       K10064  ASGR2; asialoglycoprotein receptor 2
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K14385  SLC5A5, NIS; solute carrier family 5 (sodium/iodide cotransporter), member 5
       K14702  SLC26A4, PDS; solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4
       K00431  TPO; thyroid peroxidase [EC:1.11.1.8]
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K17231  IYD, DEHAL1; iodotyrosine deiodinase [EC:1.22.1.1]
       K17232  DUOXA2; dual oxidase maturation factor 2
       K00432  E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
       K00383  GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]
       K06233  LRP2; low density lipoprotein-related protein 2
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
     04916 Melanogenesis [PATH:ko04916]
       K05228  POMC; proopiomelanocortin
       K08725  ASIP; agouti signaling protein
       K04199  MC1R; melanocortin 1 receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K09455  MITF; microphthalmia-associated transcription factor
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K00505  TYR; tyrosinase [EC:1.14.18.1]
       K00506  TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
       K01827  DCT; dopachrome tautomerase [EC:5.3.3.12]
       K16366  EDN1; endothelin-1
       K04198  EDNRB; endothelin receptor type B
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
     04260 Cardiac muscle contraction [PATH:ko04260]
     04261 Adrenergic signaling in cardiomyocytes [PATH:ko04261]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K04926  KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
       K04894  KCNE1; potassium voltage-gated channel Isk-related subfamily E member 1
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K04838  SCN5A; voltage-gated sodium channel type V alpha
       K04839  SCN7A, SCN6A; voltage-gated sodium channel type VII alpha
       K04845  SCN1B; voltage-gated sodium channel type I beta
       K04848  SCN4B; voltage-gated sodium channel type IV beta
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04962  RYR2; ryanodine receptor 2
       K04382  PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
       K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
       K04354  PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
       K11583  PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
       K11584  PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K05865  TNNC1; troponin C, slow skeletal and cardiac muscles
       K12044  TNNI3; troponin I, cardiac muscle
       K12045  TNNT2; troponin T, cardiac muscle
       K10373  TPM1; tropomyosin 1
       K10374  TPM2; tropomyosin 2
       K09290  TPM3; tropomyosin 3
       K10375  TPM4; tropomyosin 4
       K12314  ACTC1; actin, alpha cardiac muscle
       K17751  MYH6_7; myosin heavy chain 6/7
       K10351  MYL2; myosin regulatory light chain 2
       K12749  MYL3; myosin light chain 3
       K12750  MYL4; myosin light chain 4
       K05852  PLN; phospholamban
       K04166  AGTR1; angiotensin II receptor type 1
       K04167  AGTR2; angiotensin II receptor type 2
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K08050  PPP1R1A; protein phosphatase 1 regulatory subunit 1A
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K09052  CREM; cAMP response element modulator
       K02161  BCL2; apoptosis regulator BCL-2
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
     04270 Vascular smooth muscle contraction [PATH:ko04270]
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K09821  AGT; angiotensinogen
       K04166  AGTR1; angiotensin II receptor type 1
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K04197  EDNRA; endothelin receptor type A
       K05242  AVP; arginine vasopressin
       K04226  AVPR1A; arginine vasopressin receptor 1A
       K04227  AVPR1B; arginine vasopressin receptor 1B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K17687  CYP4A11; alkane 1-monooxygenase [EC:1.14.15.3]
       K17688  CYP4A22; alkane 1-monooxygenase [EC:1.14.15.3]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05274  KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
       K04937  KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
       K04938  KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
       K04939  KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
       K04941  KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K02183  CALM; calmodulin
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K12751  MYL6; myosin light chain 6
       K12755  MYL9; myosin regulatory light chain 9
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K12327  CALD1; caldesmon
       K12313  ACTA2; actin, aortic smooth muscle
       K12315  ACTG2; actin, gamma-enteric smooth muscle
       K12328  PPP1R14A, CPI17; protein phosphatase 1 regulatory subunit 14A
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04267  ADORA2B; adenosine receptor A2b
       K04263  PTGIR; prostacyclin receptor
       K12332  CALCA; calcitonin
       K12333  ADM; adrenomedullin
       K04577  CALCRL; calcitonin receptor-like
       K08447  RAMP1; receptor activity modifying protein 1
       K08448  RAMP2; receptor activity modifying protein 2
       K08449  RAMP3; receptor activity modifying protein 3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12334  NPPA; natriuretic peptide A
       K12335  NPPB; natriuretic peptide B
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K12336  NPPC; natriuretic peptide C
       K12324  ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
       K12337  MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
 
   Digestive system
     04970 Salivary secretion [PATH:ko04970]
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04143  ADRB3; adrenergic receptor beta-3
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K13504  VAMP2; vesicle-associated membrane protein 2
       K04135  ADRA1A; adrenergic receptor alpha-1A
       K04136  ADRA1B; adrenergic receptor alpha-1B
       K04137  ADRA1D; adrenergic receptor alpha-1D
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04963  RYR3; ryanodine receptor 3
       K02183  CALM; calmodulin
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K18152  BST1; ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
       K13879  BEST2, VMD2L1; bestrophin-2
       K09867  AQP5; aquaporin-5
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
       K04945  KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K13855  SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K04975  TRPV6; transient receptor potential cation channel subfamily V member 6
       K13908  MUC5B, MG1; mucin-5B
       K13909  MUC7, MG2; mucin-7
       K13910  PRH1_2; salivary acidic proline-rich phosphoprotein 1/2
       K13911  PRB1_2; basic salivary proline-rich protein 1/2
       K13912  DMBT1; deleted in malignant brain tumors 1 protein
       K13897  CST1; cystatin-SN
       K13898  CST2; cystatin-SA
       K13899  CST3; cystatin-C
       K13900  CST4; cystatin-S
       K13901  CST5; cystatin-D
       K13913  HTN; histatin
       K13914  STATH; statherin
       K13915  LYZ; lysozyme C [EC:3.2.1.17]
       K12550  LPO; lactoperoxidase [EC:1.11.1.7]
       K13916  CAMP, LL37; cathelicidin antimicrobial peptide
     04971 Gastric acid secretion [PATH:ko04971]
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K13768  GAST; gastrin
       K04195  CCKBR; cholecystokinin B receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08007  VIL2; villin 2 (ezrin)
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]
       K04150  HRH2; histamine receptor H2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K05237  SST; somatostatin
       K04218  SSTR2; somatostatin receptor 2
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K01542  ATP4A; H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10]
       K01543  ATP4B; H+/K+-exchanging ATPase beta polypeptide [EC:3.6.3.10]
       K04896  KCNE2; potassium voltage-gated channel Isk-related subfamily E member 2
       K04926  KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
       K04995  KCNJ1; potassium inwardly-rectifying channel subfamily J member 1
       K04996  KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
       K05003  KCNJ10; potassium inwardly-rectifying channel subfamily J member 10
       K05008  KCNJ15; potassium inwardly-rectifying channel subfamily J member 15
       K05009  KCNJ16; potassium inwardly-rectifying channel subfamily J member 16
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K04913  KCNK2; potassium channel subfamily K member 2
       K04920  KCNK10; potassium channel subfamily K member 10
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K13961  SLC9A4, NHE4; solute carrier family 9 (sodium/hydrogen exchanger), member 4
       K18245  CA2; carbonic anhydrase 2 [EC:4.2.1.1]
       K13962  SLC26A7, SUT2; solute carrier family 26 (anion exchange transporter), member 7
       K13855  SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
     04972 Pancreatic secretion [PATH:ko04972]
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K05226  CCK; cholecystokinin
       K04194  CCKAR; cholecystokinin A receptor
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K07884  RAB3D; Ras-related protein Rab-3D
       K07901  RAB8A, MEL; Ras-related protein Rab-8A
       K07904  RAB11A; Ras-related protein Rab-11A
       K07886  RAB27B; Ras-related protein Rab-27B
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K04513  RHOA; Ras homolog gene family, member A
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K01312  PRSS; trypsin [EC:3.4.21.4]
       K09632  CTRL; chymotrypsin-like protease [EC:3.4.21.-]
       K01346  CELA2; pancreatic elastase II [EC:3.4.21.71]
       K01345  CELA3; pancreatic endopeptidase E [EC:3.4.21.70]
       K08779  CPA1; carboxypeptidase A1 [EC:3.4.17.1]
       K01298  CPA2; carboxypeptidase A2 [EC:3.4.17.15]
       K08780  CPA3; carboxypeptidase A3 [EC:3.4.17.1]
       K01291  CPB1; carboxypeptidase B [EC:3.4.17.2]
       K01300  CPB2; carboxypeptidase B2 [EC:3.4.17.20]
       K14073  PNLIP, PL; pancreatic triacylglycerol lipase [EC:3.1.1.3]
       K14074  PNLIPRP1, PLRP1; pancreatic lipase-related protein 1 [EC:3.1.1.3]
       K14075  PNLIPRP2, PLRP2; pancreatic lipase-related protein 2 [EC:3.1.1.3]
       K12298  CEL; bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
       K01047  PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04962  RYR2; ryanodine receptor 2
       K01242  CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
       K18152  BST1; ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20]
       K14077  TPCN2; two pore calcium channel protein 2
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K05027  CLCA1; calcium-activated chloride channel regulator 1
       K05028  CLCA2; calcium-activated chloride channel regulator 2
       K05030  CLCA4; calcium-activated chloride channel regulator 4
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K04926  KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
       K04936  KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
       K05850  ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K13855  SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
       K05263  SCT; secretin
       K04588  SCTR; secretin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K14078  SLC26A3, DRA; solute carrier family 26 (chloride anion exchanger), member 3
       K13575  SLC4A4, NBC1; solute carrier family 4 (sodium bicarbonate cotransporter), member 4
       K18245  CA2; carbonic anhydrase 2 [EC:4.2.1.1]
     04976 Bile secretion [PATH:ko04976]
       K01253  EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
       K03460  SLCO1A; solute carrier organic anion transporter family, member 1A
       K05043  SLCO1B; solute carrier organic anion transporter family, member 1B
       K14341  SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1
       K08204  SLC22A7, OAT2; MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 7
       K08205  SLC22A8, OAT3; MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 8
       K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
       K00021  HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
       K13885  SCARB1; scavenger receptor class B, member 1
       K12473  LDLR; low-density lipoprotein receptor
       K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
       K00489  CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.13.17]
       K08537  NR1H4, FXR; farnesoid X receptor
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08563  NR0B2, SHP; nuclear receptor subfamily 0 group B member 2
       K11822  SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
       K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
       K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
       K09877  AQP9; aquaporin-9
       K09869  AQP8; aquaporin-8
       K05683  ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)
       K05684  ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
       K05664  ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
       K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
       K05681  ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2
       K18245  CA2; carbonic anhydrase 2 [EC:4.2.1.1]
       K13855  SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
       K05658  ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44]
       K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K13857  SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
       K05667  ABCC3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3
       K05673  ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
       K14360  OSTALPHA, OSTA, SLC51A1; organic solute transporter subunit alpha
       K14361  OSTBETA, OSTB, SLC51A2; organic solute transporter subunit beta
       K04943  KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K04588  SCTR; secretin receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05031  CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
       K13575  SLC4A4, NBC1; solute carrier family 4 (sodium bicarbonate cotransporter), member 4
       K09866  AQP4; aquaporin-4
       K09864  AQP1; aquaporin-1
       K14342  SLC10A2, ASBT; solute carrier family 10 (sodium/bile acid cotransporter), member 2
       K14158  SLC5A1, SGLT1; solute carrier family 5 (sodium/glucose cotransporter), member 1
       K12040  SLC9A3, NHE3; solute carrier family 9 (sodium/hydrogen exchanger), member 3
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
     04973 Carbohydrate digestion and absorption [PATH:ko04973]
     04974 Protein digestion and absorption [PATH:ko04974]
     04975 Fat digestion and absorption [PATH:ko04975]
     04977 Vitamin digestion and absorption [PATH:ko04977]
     04978 Mineral absorption [PATH:ko04978]
 
   Excretory system
     04962 Vasopressin-regulated water reabsorption [PATH:ko04962]
       K05242  AVP; arginine vasopressin
       K04228  AVPR2; arginine vasopressin receptor 2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12462  ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09865  AQP2; aquaporin-2
       K07904  RAB11A; Ras-related protein Rab-11A
       K07905  RAB11B; Ras-related protein Rab-11B
       K10413  DYNC1H; dynein heavy chain 1, cytosolic
       K10414  DYNC2H, DNCH2; dynein heavy chain 2, cytosolic
       K10415  DYNC1I, DNCI; dynein intermediate chain, cytosolic
       K10416  DYNC1LI, DNCLI; dynein light intermediate chain 1, cytosolic
       K10417  DYNC2LI; dynein light intermediate chain 2, cytosolic
       K10418  DYNLL; dynein light chain LC8-type
       K04648  DCTN1; dynactin 1
       K10424  DCTN2; dynactin 2
       K10426  DCTN4; dynactin 4
       K10427  DCTN5; dynactin 5
       K10428  DCTN6; dynactin 6
       K13504  VAMP2; vesicle-associated membrane protein 2
       K06027  NSF; vesicle-fusing ATPase [EC:3.6.4.6]
       K13502  STX4; syntaxin 4
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K09866  AQP4; aquaporin-4
       K09876  AQP3; aquaporin-3
     04960 Aldosterone-regulated sodium reabsorption [PATH:ko04960]
     04961 Endocrine and other factor-regulated calcium reabsorption [PATH:ko04961]
       K04585  PTHR1; parathyroid hormone receptor 1
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K08539  NR1I1, VDR; vitamin D3 receptor
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K04974  TRPV5; transient receptor potential cation channel subfamily V member 5
       K14756  KL; klotho [EC:3.2.1.31]
       K01528  DNM; dynamin GTPase [EC:3.6.5.5]
       K11824  AP2A; AP-2 complex subunit alpha
       K11825  AP2B1; AP-2 complex subunit beta-1
       K11826  AP2M1; AP-2 complex subunit mu-1
       K11827  AP2S1; AP-2 complex subunit sigma-1
       K04644  CLTA, LCA; clathrin light chain A
       K04645  CLTB, LCB; clathrin light chain B
       K04646  CLTC; clathrin heavy chain
       K07904  RAB11A; Ras-related protein Rab-11A
       K14757  CALB1, CALB; calbindin D28
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K01325  KLK1_2; tissue kallikrein [EC:3.4.21.35]
       K03916  BDKRB2; bradykinin receptor B2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
     04964 Proximal tubule bicarbonate reclamation [PATH:ko04964]
     04966 Collecting duct acid secretion [PATH:ko04966]
 
   Nervous system
     04724 Glutamatergic synapse [PATH:ko04724]
       K14990  SLC38A1, SNAT1, GLNT; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1
       K14207  SLC38A2, SNAT2; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K12302  SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
       K05201  GRIK1; glutamate receptor, ionotropic kainate 1
       K05202  GRIK2; glutamate receptor, ionotropic kainate 2
       K05203  GRIK3; glutamate receptor, ionotropic kainate 3
       K05204  GRIK4; glutamate receptor, ionotropic kainate 4
       K05205  GRIK5; glutamate receptor, ionotropic kainate 5
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K11828  DLG4, PSD95; discs large protein 4
       K15008  DLGAP1, GKAP; discs, large-associated protein 1
       K15009  SHANK; SH3 and multiple ankyrin repeat domains protein
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K15010  HOMER; homer
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04605  GRM2_3; metabotropic glutamate receptor 2/3
       K04607  GRM4; metabotropic glutamate receptor 4
       K04608  GRM6_7_8; metabotropic glutamate receptor 6/7/8
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K05613  SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
       K05618  SLC1A7, EAAT5; solute carrier family 1 (glutamate transporter), member 7
       K05612  SLC1A1, EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1
       K05617  SLC1A6, EAAT4; solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K05614  SLC1A3, EAAT1; solute carrier family 1 (glial high affinity glutamate transporter), member 3
       K01915  glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
       K13576  SLC38A3, SNAT3; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3
     04727 GABAergic synapse [PATH:ko04727]
       K14990  SLC38A1, SNAT1, GLNT; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1
       K14207  SLC38A2, SNAT2; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2
       K01425  glsA, GLS; glutaminase [EC:3.5.1.2]
       K01580  E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
       K15015  SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
       K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
       K05175  GABRA; gamma-aminobutyric acid receptor subunit alpha
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K05186  GABRG; gmma-aminobutyric acid receptor subunit gamma
       K05184  GABRD; gamma-aminobutyric acid receptor subunit delta
       K05185  GABRE; gamma-aminobutyric acid receptor subunit epsilon
       K05192  GABRQ; gamma-aminobutyric acid receptor subunit theta
       K05189  GABRP; gamma-aminobutyric acid receptor subunit pi
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04647  HAP1; huntingtin-associated protein 1
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K06027  NSF; vesicle-fusing ATPase [EC:3.6.4.6]
       K15374  TRAK2, GRIF1; trafficking kinesin-binding protein 2
       K15375  PLCL1, PRIP; inactive phospholipase C-like protein 1
       K15376  GPHN; gephyrin [EC:2.10.1.1 2.7.7.75]
       K05190  GABRR; gamma-aminobutyric acid receptor subunit rho
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05034  SLC6A1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
       K01915  glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
       K13576  SLC38A3, SNAT3; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3
       K14992  SLC38A5, SNAT5; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5
     04725 Cholinergic synapse [PATH:ko04725]
       K00623  CHAT; choline O-acetyltransferase [EC:2.3.1.6]
       K01049  ACHE; acetylcholinesterase [EC:3.1.1.7]
       K14636  SLC18A3, VACHT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular acetylcholine transporter), member 3
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04131  CHRM3; muscarinic acetylcholine receptor M3
       K04133  CHRM5; muscarinic acetylcholine receptor M5
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04926  KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
       K04927  KCNQ2; potassium voltage-gated channel KQT-like subfamily member 2
       K04928  KCNQ3; potassium voltage-gated channel KQT-like subfamily member 3
       K04929  KCNQ4; potassium voltage-gated channel KQT-like subfamily member 4
       K04930  KCNQ5; potassium voltage-gated channel KQT-like subfamily member 5
       K04996  KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
       K05005  KCNJ12; potassium inwardly-rectifying channel subfamily J member 12
       K04998  KCNJ4; potassium inwardly-rectifying channel subfamily J member 4
       K05007  KCNJ14; potassium inwardly-rectifying channel subfamily J member 14
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04132  CHRM4; muscarinic acetylcholine receptor M4
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04809  CHRNA7; nicotinic acetylcholine receptor alpha-7
       K04806  CHRNA4; nicotinic acetylcholine receptor alpha-4
       K04813  CHRNB2; nicotinic acetylcholine receptor beta-2
       K04805  CHRNA3; nicotinic acetylcholine receptor alpha-3
       K04815  CHRNB4; nicotinic acetylcholine receptor beta-4
       K04808  CHRNA6; nicotinic acetylcholine receptor alpha-6
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02161  BCL2; apoptosis regulator BCL-2
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K14387  SLC5A7, CHT1; solute carrier family 5 (high affinity choline transporter), member 7
     04728 Dopaminergic synapse [PATH:ko04728]
     04726 Serotonergic synapse [PATH:ko04726]
     04720 Long-term potentiation [PATH:ko04720]
     04730 Long-term depression [PATH:ko04730]
     04723 Retrograde endocannabinoid signaling [PATH:ko04723]
       K12302  SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04603  GRM1; metabotropic glutamate receptor 1
       K04604  GRM5; metabotropic glutamate receptor 5
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K13985  NAPEPLD; N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K13806  DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13700  ABHD6; abhydrolase domain-containing protein 6 [EC:3.1.1.23]
       K15528  FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
       K04277  CNR1; cannabinoid receptor 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K01054  MGLL; acylglycerol lipase [EC:3.1.1.23]
       K15015  SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
       K15291  RIMS1, RIM1; regulating synaptic membrane exocytosis protein 1
       K05175  GABRA; gamma-aminobutyric acid receptor subunit alpha
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K05186  GABRG; gmma-aminobutyric acid receptor subunit gamma
       K05184  GABRD; gamma-aminobutyric acid receptor subunit delta
       K05185  GABRE; gamma-aminobutyric acid receptor subunit epsilon
       K05192  GABRQ; gamma-aminobutyric acid receptor subunit theta
       K05189  GABRP; gamma-aminobutyric acid receptor subunit pi
       K05190  GABRR; gamma-aminobutyric acid receptor subunit rho
     04721 Synaptic vesicle cycle [PATH:ko04721]
     04722 Neurotrophin signaling pathway [PATH:ko04722]
 
   Sensory system
     04744 Phototransduction [PATH:ko04744]
     04745 Phototransduction - fly [PATH:ko04745]
     04740 Olfactory transduction [PATH:ko04740]
     04742 Taste transduction [PATH:ko04742]
       K04824  SCNN1A; amiloride-sensitive sodium channel subunit alpha
       K04825  SCNN1B; amiloride-sensitive sodium channel subunit beta
       K04827  SCNN1G; amiloride-sensitive sodium channel subunit gamma
       K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K04607  GRM4; metabotropic glutamate receptor 4
       K04624  TAS1R1; taste receptor type 1 member 1
       K04626  TAS1R3; taste receptor type 1 member 3
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K08474  TAS2R; taste receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04980  TRPM5; transient receptor potential cation channel subfamily M member 5
       K04625  TAS1R2; taste receptor type 1 member 2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04885  KCNB1; potassium voltage-gated channel Shab-related subfamily B member 1
     04750 Inflammatory mediator regulation of TRP channels [PATH:ko04750]
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04157  HTR2; 5-hydroxytryptamine receptor 2
       K04149  HRH1; histamine receptor H1
       K04269  P2RY2; purinergic receptor P2Y, G protein-coupled, 2
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K16342  PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
       K16343  PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
       K00458  ALOX12; arachidonate 12-lipoxygenase [EC:1.13.11.31]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K04984  TRPA1, ANKTM1; transient receptor potential cation channel subfamily A member 1
       K05222  TRPV1; transient receptor potential cation channel subfamily V member 1
       K04829  ASIC1, ACCN2, BNAC2; acid-sensing ion channel 1
       K04828  ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
       K04830  ASIC3, ACCN3; acid-sensing ion channel 3
       K04831  ASIC4, ACCN4, BNAC4; acid-sensing ion channel 4
       K04832  ASIC5, ACCN5; acid-sensing ion channel 5
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K05451  NGFA; nerve growth factor, alpha
       K02582  NGFB; nerve growth factor, beta
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04983  TRPM8; transient receptor potential cation channel subfamily M member 8
       K04259  PTGER2; prostaglandin E receptor 2
       K04261  PTGER4; prostaglandin E receptor 4
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04973  TRPV4; transient receptor potential cation channel subfamily V member 4
       K04234  F2RL1, PAR2; coagulation factor II (thrombin) receptor-like 1
       K07413  CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
       K07418  CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05459  IGF1; insulin-like growth factor 1
       K04971  TRPV2; transient receptor potential cation channel subfamily V member 2
       K04972  TRPV3; transient receptor potential cation channel subfamily V member 3
 
   Development
 
   Environmental adaptation
     04710 Circadian rhythm [PATH:ko04710]
     04713 Circadian entrainment [PATH:ko04713]
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04445  MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04961  RYR1; ryanodine receptor 1
       K04962  RYR2; ryanodine receptor 2
       K04963  RYR3; ryanodine receptor 3
       K16513  NOS1AP, CAPON; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
       K07843  RASD1; RAS, dexamethasone-induced Ras-related protein 1
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K04854  CACNA1G; voltage-dependent calcium channel T type alpha-1G
       K04855  CACNA1H; voltage-dependent calcium channel T type alpha-1H
       K04856  CACNA1I; voltage-dependent calcium channel T type alpha-1I
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K11265  ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K12318  GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
       K12319  GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
       K07376  PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04286  MTNR1B; melatonin receptor type 1B
       K04285  MTNR1A; melatonin receptor type 1A
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K02633  PER; period circadian protein
       K04379  FOS; proto-oncogene protein c-fos
     04711 Circadian rhythm - fly [PATH:ko04711]
     04712 Circadian rhythm - plant [PATH:ko04712]
     04626 Plant-pathogen interaction [PATH:ko04626]
 
 Human Diseases
 
   Cancers
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
     05030 Cocaine addiction [PATH:ko05030]
     05031 Amphetamine addiction [PATH:ko05031]
     05032 Morphine addiction [PATH:ko05032]
       K04215  OPRM1; mu-type opioid receptor
       K04144  DRD1; dopamine receptor D1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K15015  SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
       K04997  KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
       K05000  KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
       K05002  KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
       K04999  KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
       K04344  CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
       K04849  CACNA1B; voltage-dependent calcium channel N type alpha-1B
       K05175  GABRA; gamma-aminobutyric acid receptor subunit alpha
       K05181  GABRB; gamma-aminobutyric acid receptor subunit beta
       K05186  GABRG; gmma-aminobutyric acid receptor subunit gamma
       K05184  GABRD; gamma-aminobutyric acid receptor subunit delta
       K05185  GABRE; gamma-aminobutyric acid receptor subunit epsilon
       K05192  GABRQ; gamma-aminobutyric acid receptor subunit theta
       K05189  GABRP; gamma-aminobutyric acid receptor subunit pi
       K05190  GABRR; gamma-aminobutyric acid receptor subunit rho
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
       K08291  GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
       K04439  ARRB; beta-arrestin
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K13755  PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
       K18283  PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13296  PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
       K13293  PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
       K18436  PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
       K18437  PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
       K18438  PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
       K13298  PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
       K04265  ADORA1; adenosine A1 receptor
     05033 Nicotine addiction [PATH:ko05033]
     05034 Alcoholism [PATH:ko05034]
 
   Cardiovascular diseases
     05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
     05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
       K06480  ITGA1; integrin alpha 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06483  ITGA4; integrin alpha 4
       K06484  ITGA5; integrin alpha 5
       K06485  ITGA6; integrin alpha 6
       K06583  ITGA7; integrin alpha 7
       K06584  ITGA8; integrin alpha 8
       K06585  ITGA9; integrin alpha 9
       K06586  ITGA10; integrin alpha 10
       K06587  ITGA11; integrin alpha 11
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K06493  ITGB3; integrin beta 3
       K06525  ITGB4; integrin beta 4
       K06588  ITGB5; integrin beta 5
       K06589  ITGB6; integrin beta 6
       K06590  ITGB7; integrin beta 7
       K06591  ITGB8; integrin beta 8
       K12563  SGCD; delta-sarcoglycan
       K12564  SGCG; gamma-sarcoglycan
       K12565  SGCA; alpha-sarcoglycan
       K12566  SGCB; beta-sarcoglycan
       K06265  DAG1; dystroglycan 1
       K07610  DES; desmin
       K10366  DMD; dystrophin
       K05692  ACTB_G1; actin beta/gamma 1
       K12567  TTN; titin [EC:2.7.11.1]
       K12045  TNNT2; troponin T, cardiac muscle
       K05865  TNNC1; troponin C, slow skeletal and cardiac muscles
       K12044  TNNI3; troponin I, cardiac muscle
       K12314  ACTC1; actin, alpha cardiac muscle
       K10373  TPM1; tropomyosin 1
       K10374  TPM2; tropomyosin 2
       K09290  TPM3; tropomyosin 3
       K10375  TPM4; tropomyosin 4
       K12568  MYBPC3; myosin-binding protein C, cardiac-type
       K12749  MYL3; myosin light chain 3
       K10351  MYL2; myosin regulatory light chain 2
       K12569  EMD; emerin
       K12641  LMNA; lamin A/C
       K06856  IGH; immunoglobulin heavy chain
       K04141  ADRB1; adrenergic receptor beta-1
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04862  CACNB1; voltage-dependent calcium channel beta-1
       K04863  CACNB2; voltage-dependent calcium channel beta-2
       K04864  CACNB3; voltage-dependent calcium channel beta-3
       K04865  CACNB4; voltage-dependent calcium channel beta-4
       K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
       K04859  CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
       K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
       K04861  CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
       K04866  CACNG1; voltage-dependent calcium channel gamma-1
       K04867  CACNG2; voltage-dependent calcium channel gamma-2
       K04868  CACNG3; voltage-dependent calcium channel gamma-3
       K04869  CACNG4; voltage-dependent calcium channel gamma-4
       K04870  CACNG5; voltage-dependent calcium channel gamma-5
       K04871  CACNG6; voltage-dependent calcium channel gamma-6
       K04872  CACNG7; voltage-dependent calcium channel gamma-7
       K04873  CACNG8; voltage-dependent calcium channel gamma-8
       K04962  RYR2; ryanodine receptor 2
       K05852  PLN; phospholamban
       K05459  IGF1; insulin-like growth factor 1
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K03156  TNFA; tumor necrosis factor superfamily, member 2
     05416 Viral myocarditis [PATH:ko05416]
 
   Endocrine and metabolic diseases
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06724  NRP1; neuropilin 1
       K06527  VCAM1; vascular cell adhesion molecule 1
       K06450  CD3D; T-cell surface glycoprotein CD3 delta chain
       K06451  CD3E; T-cell surface glycoprotein CD3 epsilon chain
       K06452  CD3G; T-cell surface glycoprotein CD3 gamma chain
       K06490  ICAM1; intercellular adhesion molecule 1
       K05718  ITGAL; integrin alpha L
       K06464  ITGB2; integrin beta 2
       K06271  TLN; talin
       K04377  MYC; Myc proto-oncogene protein
       K08874  TRRAP; transformation/transcription domain-associated protein
       K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
       K10151  CCND2; cyclin D2
       K15304  RANBP3; Ran-binding protein 3
       K07936  RAN; GTP-binding nuclear protein Ran
       K14290  XPO1, CRM1; exportin-1
       K06751  MHC1; major histocompatibility complex, class I
       K08057  CALR; calreticulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K08054  CANX; calnexin
       K05069  IL2RB; interleukin 2 receptor beta
       K05070  IL2RG; interleukin 2 receptor gamma
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05770  BZRP; benzodiazapine receptor
       K15305  VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
       K15306  RANBP1; Ran-binding protein 1
       K06679  MAD1; mitotic spindle assembly checkpoint protein MAD1
       K02537  MAD2; mitotic spindle assembly checkpoint protein MAD2
       K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
       K02180  BUB3; cell cycle arrest protein BUB3
       K03363  CDC20; cell division cycle 20, cofactor of APC complex
       K03348  APC1; anaphase-promoting complex subunit 1
       K03349  APC2; anaphase-promoting complex subunit 2
       K03350  APC3, CDC27; anaphase-promoting complex subunit 3
       K03351  APC4; anaphase-promoting complex subunit 4
       K03352  APC5; anaphase-promoting complex subunit 5
       K03353  APC6, CDC16; anaphase-promoting complex subunit 6
       K03354  APC7; anaphase-promoting complex subunit 7
       K03355  APC8, CDC23; anaphase-promoting complex subunit 8
       K03356  APC9; anaphase-promoting complex subunit 9
       K03357  APC10, DOC1; anaphase-promoting complex subunit 10
       K03358  APC11; anaphase-promoting complex subunit 11
       K03359  APC12, CDC26; anaphase-promoting complex subunit 12
       K12416  SWM1, APC13; anaphase-promoting complex subunit SWM1
       K06635  PTTG; securin
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04802  PCNA; proliferating cell nuclear antigen
       K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
       K02328  POLD2; DNA polymerase delta subunit 2
       K03504  POLD3; DNA polymerase delta subunit 3
       K03505  POLD4; DNA polymerase delta subunit 4
       K02324  POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
       K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
       K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
       K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
       K04503  CCND1; cyclin D1
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K04690  FZDN, fz3; frizzled
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02105  CTNNB1; catenin beta 1
       K02085  APC; adenomatosis polyposis coli protein
       K12076  DLG1; disks large protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04448  JUN; transcription factor AP-1
       K15307  GPS2; G protein pathway suppressor 2
       K04386  IL1R1; interleukin 1 receptor type I
       K04387  IL1R2; interleukin 1 receptor type II
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K03159  TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K05151  TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K09253  RELB; transcription factor RelB
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K05429  IL2; interleukin 2
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05433  IL15; interleukin 15
       K05074  IL15RA; interleukin 15 receptor alpha
       K05405  IL6; interleukin 6
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K15308  TTP; tristetraprolin
       K08065  NFYB; nuclear transcription Y subunit beta
       K06752  MHC2; major histocompatibility complex, class II
       K04378  SRF; serum response factor
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K04375  ELK1; ETS domain-containing protein Elk-1
       K09438  SPI1; transcription factor PU.1
       K02678  ETS, pnt; c-ets proto-oncogene protein
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04379  FOS; proto-oncogene protein c-fos
       K09203  EGR1; early growth response protein 1
       K12496  EGR2; early growth response protein 2
       K04502  FOSL1; fos-like antigen 1
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09052  CREM; cAMP response element modulator
       K09053  ATF1; activating transcription factor 1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K09032  ATF3, LRF1; activating transcription factor 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09027  XBP1; X box-binding protein 1
       K15309  CRTC1, TORC1; CREB-regulated transcription coactivator 1
       K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
       K16334  CRTC3, TORC3; CREB-regulated transcription coactivator 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09063  TCF3, E2A; transcription factor E2-alpha
       K02330  POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K09420  MYB; myb proto-oncogene protein
       K09421  MYBL; myb-related protein
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K15310  TP53INP1; tumor protein p53-inducible nuclear protein 1
       K09341  MSX; homeobox protein MSX
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
     05161 Hepatitis B [PATH:ko05161]
     05160 Hepatitis C [PATH:ko05160]
     05168 Herpes simplex infection [PATH:ko05168]
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 27, 2014