 Metabolism
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 Carbohydrate metabolism
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Energy metabolism
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Lipid metabolism
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Nucleotide metabolism
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00230 Purine metabolism [PATH:ko00230]
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 K13988 NUDT9; ADP-ribose pyrophosphatase [EC:3.6.1.13]
K01515 nudF; ADP-ribose pyrophosphatase [EC:3.6.1.13]
K01517 ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
K13987 NUDT5; ADP-sugar pyrophosphatase [EC:3.6.1.13 3.6.1.-]
K08312 nudE; ADP-ribose diphosphatase [EC:3.6.1.-]
K01839 deoB; phosphopentomutase [EC:5.4.2.7]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00948 PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00764 purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K11788 ADE5; phosphoribosylamine--glycine ligase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 6.3.3.1]
K01945 purD; phosphoribosylamine--glycine ligase [EC:6.3.4.13]
K13713 purCD; fusion protein PurCD [EC:6.3.2.6 6.3.4.13]
K00601 E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:2.1.2.2]
K01952 purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K11808 ADE2; phosphoribosylaminoimidazole carboxylase [EC:4.1.1.21]
K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
K01756 purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K01492 E2.1.2.3; phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.3]
K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.-]
K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
K00759 E2.4.2.7, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K11751 ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45]
K03787 surE; 5'-nucleotidase [EC:3.1.3.5]
K08722 yfbR; 5'-nucleotidase [EC:3.1.3.5]
K08723 yjjG; 5'-nucleotidase [EC:3.1.3.5]
K00892 gsk; inosine kinase [EC:2.7.1.73]
K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]
K03815 xapA; xanthosine phosphorylase [EC:2.4.2.-]
K01239 iunH; purine nucleosidase [EC:3.2.2.1]
K10213 rihB; ribosylpyrimidine nucleosidase [EC:3.2.2.8]
K00760 hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K15780 tilS-hprT; bifunctional protein TilS/HprT [EC:6.3.4.19 2.4.2.8]
K00088 E1.1.1.205, guaB; IMP dehydrogenase [EC:1.1.1.205]
K00940 E2.7.4.6, ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K14641 APY1_2; apyrase [EC:3.6.1.5]
K14642 YND1; golgi apyrase [EC:3.6.1.5]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K12305 ENTPD4, LALP70; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K01519 ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.19]
K02428 rdgB; dITP/XTP pyrophosphatase [EC:3.6.1.19]
K04765 mazG; ATP diphosphatase [EC:3.6.1.8]
K00769 gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
K03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K00087 ygeS, xdhA; xanthine dehydrogenase molybdenum-binding subunit [EC:1.17.1.4]
K13479 ygeT, xdhB; xanthine dehydrogenase FAD-binding subunit [EC:1.17.1.4]
K13480 ygeU, xdhC; xanthine dehydrogenase iron-sulfur-binding subunit
K13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]
K13482 xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]
K11177 yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
K11178 yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
K13483 yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
K01518 E3.6.1.17; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K01951 E6.3.5.2, guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00364 E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]
K01487 E3.5.4.3, guaD; guanine deaminase [EC:3.5.4.3]
K00942 E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]
K00873 PK, pyk; pyruvate kinase [EC:2.7.1.40]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00524 nrdJ; ribonucleotide reductase, class II [EC:1.17.4.1]
K00525 E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
K00526 E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K00527 nrdD; ribonucleoside-triphosphate reductase [EC:1.17.4.2]
K00904 DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
K15518 dgk; deoxyguanosine kinase [EC:2.7.1.113]
K01129 dgt; dGTPase [EC:3.1.5.1]
K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
K13797 rpoBC; DNA-directed RNA polymerase subunit beta-beta' [EC:2.7.7.6]
K03048 rpoE; DNA-directed RNA polymerase subunit delta
K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
K13798 K13798, rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
K03050 rpoE2; DNA-directed RNA polymerase subunit E" [EC:2.7.7.6]
K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
K03054 rpoI; DNA-directed RNA polymerase subunit I [EC:2.7.7.6]
K02999 RPA1, POLR1A; DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6]
K03002 RPA2, POLR1B; DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6]
K03000 RPA12, ZNRD1; DNA-directed RNA polymerase I subunit RPA12
K03001 RPA14; DNA-directed RNA polymerase I subunit RPA14
K03003 RPA34; DNA-directed RNA polymerase I subunit RPA34
K03004 RPA43; DNA-directed RNA polymerase I subunit RPA43
K03005 RPA49, POLR1E; DNA-directed RNA polymerase I subunit RPA49
K03006 RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
K03013 RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
K03016 RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
K03007 RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
K03009 RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K03018 RPC1, POLR3A; DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6]
K03021 RPC2, POLR3B; DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6]
K03023 RPC82, POLR3C; DNA-directed RNA polymerase III subunit RPC3
K03026 RPC53, POLR3D; DNA-directed RNA polymerase III subunit RPC4
K14721 RPC37, POLR3E; DNA-directed RNA polymerase III subunit RPC5
K03027 RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1
K03019 RPC11, POLR3K; DNA-directed RNA polymerase III subunit RPC10
K03020 RPC19, POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2
K03022 RPC25, POLR3H; DNA-directed RNA polymerase III subunit RPC8
K03024 RPC31, POLR3G; DNA-directed RNA polymerase III subunit RPC7
K03025 RPC34, POLR3F; DNA-directed RNA polymerase III subunit RPC6
K02335 DPO1, polA; DNA polymerase I [EC:2.7.7.7]
K02319 DPA, polB1; DNA polymerase I [EC:2.7.7.7]
K02322 DPB1; DNA polymerase II large subunit [EC:2.7.7.7]
K02323 DPB2; DNA polymerase II small subunit [EC:2.7.7.7]
K02337 DPO3A1, dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
K03763 DPO3A2, polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
K02338 DPO3B, dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
K02343 DPO3G, dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
K02340 DPO3D1, holA; DNA polymerase III subunit delta [EC:2.7.7.7]
K02341 DPO3D2, holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
K02342 DPO3E, dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
K14159 rnhA-dnaQ; ribonuclease HI / DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]
K02345 DPO3T, holE; DNA polymerase III subunit theta [EC:2.7.7.7]
K02339 DPO3C, holC; DNA polymerase III subunit chi [EC:2.7.7.7]
K02344 DPO3P, holD; DNA polymerase III subunit psi [EC:2.7.7.7]
K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
K02321 POLA2; DNA polymerase alpha subunit B
K02684 PRI1; DNA primase small subunit [EC:2.7.7.-]
K02685 PRI2; DNA primase large subunit [EC:2.7.7.-]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K01139 spoT, HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
K01514 PPX1; exopolyphosphatase [EC:3.6.1.11]
K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5]
K07816 E2.7.6.5X; putative GTP pyrophosphokinase [EC:2.7.6.5]
K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
K05851 E4.6.1.1A, cyaA; adenylate cyclase, class 1 [EC:4.6.1.1]
K05873 E4.6.1.1B, cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K11029 cyaA; anthrax edema toxin adenylate cyclase [EC:4.6.1.1]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E_F; guanylate cyclase 2D/E/F [EC:4.6.1.2]
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K01769 E4.6.1.2; guanylate cyclase, other [EC:4.6.1.2]
K01120 PDE; 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13296 PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K08718 PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
K13756 PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
K13757 PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13759 PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13760 PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13763 PDE6N; cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35]
K13761 PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01939 E6.3.4.4, purA; adenylosuccinate synthase [EC:6.3.4.4]
K01490 E3.5.4.6, AMPD; AMP deaminase [EC:3.5.4.6]
K00856 E2.7.1.20, ADK; adenosine kinase [EC:2.7.1.20]
K00893 DCK; deoxycitidine kinase [EC:2.7.1.74]
K15519 dck; deoxyadenosine/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]
K01488 E3.5.4.4, ADA, add; adenosine deaminase [EC:3.5.4.4]
K01241 amn; AMP nucleosidase [EC:3.2.2.4]
K01486 ade; adenine deaminase [EC:3.5.4.2]
K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
K08693 E3.1.3.6; 3'-nucleotidase [EC:3.1.3.6]
K00939 E2.7.4.3, adk; adenylate kinase [EC:2.7.4.3]
K01509 E3.6.1.3; adenosinetriphosphatase [EC:3.6.1.3]
K01553 E3.6.4.1; myosin ATPase [EC:3.6.4.1]
K06928 K06928; nucleoside-triphosphatase THEP1 [EC:3.6.1.15]
K10353 E2.7.1.76, dak; deoxyadenosine kinase [EC:2.7.1.76]
K00985 E2.7.7.48; RNA-directed RNA polymerase [EC:2.7.7.48]
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
K13293 PDE4; cAMP-specific phosphodiesterase [EC:3.1.4.53]
K13294 PDEB2, PDE2B; cAMP-specific phosphodiesterase [EC:3.1.4.53]
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K00988 APA1_2; ATP adenylyltransferase [EC:2.7.7.53]
K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
K00958 E2.7.7.4C, met3; sulfate adenylyltransferase [EC:2.7.7.4]
K00365 E1.7.3.3; urate oxidase [EC:1.7.3.3]
K16838 pucL; urate oxidase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:1.7.3.3 4.1.1.-]
K16839 hpxO; FAD-dependent urate hydroxylase [EC:1.14.13.113]
K07127 uraH, pucM, hiuH; 5-hydroxyisourate hydrolase [EC:3.5.2.17]
K13484 TTHL; 5-hydroxyisourate hydrolase / 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:3.5.2.17 4.1.1.-]
K13485 PRHOXNB, URAD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.-]
K16840 hpxQ; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.-]
K16841 hpxA; allantoin racemase [EC:5.1.99.3]
K01466 allB; allantoinase [EC:3.5.2.5]
K16842 hpxB; allantoinase [EC:3.5.2.5]
K01477 alc, ALLC; allantoicase [EC:3.5.3.4]
K01483 allA; ureidoglycolate hydrolase [EC:3.5.3.19]
K02083 allC; allantoate deiminase [EC:3.5.3.9]
K14977 ylbA; ureidoglycine aminohydrolase [EC:3.5.3.-]
K16856 ugl; ureidoglycolate lyase [EC:4.3.2.3]
K01427 URE; urease [EC:3.5.1.5]
K01428 ureC; urease subunit alpha [EC:3.5.1.5]
K01429 ureB; urease subunit beta [EC:3.5.1.5]
K01430 ureA; urease subunit gamma [EC:3.5.1.5]
K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5]
K00073 allD; ureidoglycolate dehydrogenase [EC:1.1.1.154]
K00926 arcC; carbamate kinase [EC:2.7.2.2]
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00240 Pyrimidine metabolism [PATH:ko00240]
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Amino acid metabolism
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Metabolism of other amino acids
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Glycan biosynthesis and metabolism
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Metabolism of cofactors and vitamins
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Metabolism of terpenoids and polyketides
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Biosynthesis of other secondary metabolites
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Xenobiotics biodegradation and metabolism
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Enzyme families
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Genetic Information Processing
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Environmental Information Processing
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Cellular Processes
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Transport and catabolism
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Cell motility
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Cell growth and death
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04110 Cell cycle [PATH:ko04110]
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04111 Cell cycle - yeast [PATH:ko04111]
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04112 Cell cycle - Caulobacter [PATH:ko04112]
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04113 Meiosis - yeast [PATH:ko04113]
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04114 Oocyte meiosis [PATH:ko04114]
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K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K08556 NR3C3, PGR; progesterone receptor
K08557 NR3C4, AR; androgen receptor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11481 AURKA; aurora kinase A [EC:2.7.11.1]
K02602 ORB; oo18 RNA-binding protein
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04373 RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K08694 SPDY, RINGO; speedy
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06269 PPP1C; protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
K08836 SLK; STE20-like kinase [EC:2.7.11.1]
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K05867 CDC25C; cell division cycle 25C [EC:3.1.3.48]
K13056 C3H-4; CCCH zinc finger protein C3H-4
K03868 RBX1, ROC1; RING-box protein 1
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K10292 FBXO5, EMI1; F-box protein 5
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03356 APC9; anaphase-promoting complex subunit 9
K03357 APC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K10318 FBXO43, EMI2; F-box protein 43
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K13054 REC8L; meiotic recombination protein REC8, animal type
K13055 STAG3; cohesin complex subunit SA-3
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3, CSPG6; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K06626 CCNE; cyclin E
K11580 SGOL1; shugoshin-like 1
K11584 PPP2R5; protein phosphatase 2 (formerly 2A), regulatory subunit B'
K03456 PPP2R1; protein phosphatase 2 (formerly 2A), regulatory subunit A
K04382 PPP2C; protein phosphatase 2 (formerly 2A), catalytic subunit [EC:3.1.3.16]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
|
04210 Apoptosis [PATH:ko04210]
|
04115 p53 signaling pathway [PATH:ko04115]
|
|
Cell communication
|
04510 Focal adhesion [PATH:ko04510]
|
04520 Adherens junction [PATH:ko04520]
|
04530 Tight junction [PATH:ko04530]
|
04540 Gap junction [PATH:ko04540]
|
K07372 GJA1, CX43; gap junction protein, alpha 1
K07373 GJD2; gap junction delta-2 protein
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04359 PDGFA_B; platelet derived growth factor A/B
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04463 MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7, ERK5; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05701 TJP1, ZO1; tight junction protein 1
K04141 ADRB1; adrenergic receptor beta-1
K04144 DRD1; dopamine receptor D1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04145 DRD2; dopamine receptor D2
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04157 HTR2; 5-hydroxytryptamine receptor 2
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
|
|
Organismal Systems
|
|
Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10035 CXCL16; C-X-C motif chemokine 16
K10034 CXCL15; C-X-C motif chemokine 15
K05407 PF4, CXCL4; platelet factor 4
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K05507 XCL, SCM1; C motif chemokine 1/2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6_9; C-C motif chemokine 6/9
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K05511 CCL15_23; C-C motif chemokine 15/23
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K13072 CCL25; C-C motif chemokine 25
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05514 CCLX; C-C motif chemokine, other
K05050 IL8RB, CXCR2; interleukin 8 receptor beta
K04175 IL8RA, CXCR1; interleukin 8 receptor alpha
K04188 CXCR3, GPR9; C-X-C chemokine receptor type 3
K04189 CXCR4; C-X-C chemokine receptor type 4
K04190 CXCR5, BLR1; C-X-C chemokine receptor type 5
K04191 CXCR6; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K04183 CCR8; C-C chemokine receptor type 8
K04181 CCR6; C-C chemokine receptor type 6
K04184 CCR9; C-C chemokine receptor type 9
K04179 CCR4; C-C chemokine receptor type 4
K04182 CCR7; C-C chemokine receptor type 7
K04177 CCR2; C-C chemokine receptor type 2
K04180 CCR5; C-C chemokine receptor type 5
K04176 CCR1; C-C chemokine receptor type 1
K04178 CCR3; C-C chemokine receptor type 3
K04185 CCR10; C-C chemokine receptor type 10
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11224 STAT5B; signal transducer and activator of transcription 5B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K08891 FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K06279 SHC; src homology 2 domain-containing transforming protein C
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K09408 FOXO3; forkhead box protein O3
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK; Rho-associated protein kinase [EC:2.7.11.1]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K12367 DOCK2; dedicator of cytokinesis 2
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05760 PXN; paxillin
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K04438 CRK, CRKII; proto-oncogene C-crk
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K12361 RASGRP2; RAS guanyl-releasing protein 2
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04237 PARD3; partitioning defective protein 3
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K08011 NCF1, P47PHOX; neutrophil cytosolic factor 1
K00909 GRK1_7; rhodopsin kinase [EC:2.7.11.14]
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
|
|
Endocrine system
|
04911 Insulin secretion [PATH:ko04911]
|
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07593 SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K04979 TRPM4; transient receptor potential cation channel subfamily M member 4
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05032 ABCC8, SUR1; ATP-binding cassette subfamily C (CFTR/MRP) member 8
K05004 KCNJ11; potassium inwardly-rectifying channel subfamily J member 11
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K04942 KCNN1; potassium intermediate/small conductance calcium-activated channel subfamily N member 1
K04943 KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
K04944 KCNN3; potassium intermediate/small conductance calcium-activated channel subfamily N member 3
K04945 KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
K05325 KCNNN; potassium intermediate/small conductance calcium-activated channel subfamily N, invertebrate
K05259 GCG; glucagon
K04581 GLP1R; glucagon-like peptide 1 receptor
K05258 GIP; gastric inhibitory polypeptide
K08424 GPR119; G protein-coupled receptor 119
K05262 ADCYAP; adenylate cyclase activating polypeptide
K04587 ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K07594 IPF1, PDX1; insulin promoter factor 1
K04526 INS; insulin
K04351 RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor (GEF) 4
K15297 RIMS2, RIM2; regulating synaptic membrane exocytosis protein 2
K16882 PCLO; protein piccolo
K07882 RAB3A; Ras-related protein Rab-3A
K04194 CCKAR; cholecystokinin A receptor
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04325 FFAR1, GPR40; free fatty acid receptor 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04962 RYR2; ryanodine receptor 2
K13504 VAMP2; vesicle-associated membrane protein 2
K04560 STX1A; syntaxin 1A
K08508 SNAP23; synaptosomal-associated protein, 23kDa
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
|
04910 Insulin signaling pathway [PATH:ko04910]
|
04920 Adipocytokine signaling pathway [PATH:ko04920]
|
03320 PPAR signaling pathway [PATH:ko03320]
|
04912 GnRH signaling pathway [PATH:ko04912]
|
K05252 GNRH; gonadotropin-releasing hormone
K04280 GNRHR; gonadotropin-releasing hormone receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04420 MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04428 MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04464 MAPK7, ERK5; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04393 CDC42; cell division control protein 42
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K08521 LHB; luteinizing hormone beta polypeptide
K08522 CGA; glycoprotein hormones, alpha polypeptide
K05250 FSH; follicle stimulating hormone
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
|
04913 Ovarian Steroidogenesis [PATH:ko04913]
|
K08522 CGA; glycoprotein hormones, alpha polypeptide
K08521 LHB; luteinizing hormone beta polypeptide
K04248 LHCGR; luteinizing hormone/choriogonadotropin receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K07418 CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K00498 CYP11A; cytochrome P450, family 11, subfamily A (cholesterol monooxygenase (side-chain-cleaving)) [EC:1.14.15.6]
K00512 CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase) [EC:1.14.99.9]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.64 1.1.1.188 1.1.1.213]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K00070 HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
K05250 FSH; follicle stimulating hormone
K04247 FSHR; follicle stimulating hormone receptor
K07434 CYP19A; cytochrome P450, family 19, subfamily A [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
K07408 CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
K05498 GDF9_9B; growth differentiation factor 9/9B
K16620 BMP6; bone morphogenetic protein 6
|
04915 Estrogen signaling pathway [PATH:ko04915]
|
K08550 NR3A1, ESR1; estrogen receptor alpha
K08551 NR3A2, ESR2; estrogen receptor beta
K04079 htpG, HSP90A; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
K03283 HSPA1_8; heat shock 70kDa protein 1/8
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04246 GPR30; G protein-coupled receptor 30
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K06279 SHC; src homology 2 domain-containing transforming protein C
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04215 OPRM1; mu-type opioid receptor
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04603 GRM1; metabotropic glutamate receptor 1
|
04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
|
K08556 NR3C3, PGR; progesterone receptor
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K02602 ORB; oo18 RNA-binding protein
K08694 SPDY, RINGO; speedy
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02087 CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K06627 CCNA; cyclin A
K04367 MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
K04079 htpG, HSP90A; molecular chaperone HtpG
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04373 RPS6KA, RSK2; p90 ribosomal S6 kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K05868 CCNB; cyclin B
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06645 CDC25A; cell division cycle 25A [EC:3.1.3.48]
K05866 CDC25B; cell division cycle 25B [EC:3.1.3.48]
K05867 CDC25C; cell division cycle 25C [EC:3.1.3.48]
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13296 PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K07827 KRAS, KRAS2; GTPase KRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K06638 MAD1L; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03356 APC9; anaphase-promoting complex subunit 9
K03357 APC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
|
04916 Melanogenesis [PATH:ko04916]
|
K05228 POMC; proopiomelanocortin
K08725 ASIP; agouti signaling protein
K04199 MC1R; melanocortin 1 receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K09455 MITF; microphthalmia-associated transcription factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05461 KITLG; KIT ligand
K05091 KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K00505 TYR; tyrosinase [EC:1.14.18.1]
K00506 TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
K01827 DCT; dopachrome tautomerase [EC:5.3.3.12]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
|
04614 Renin-angiotensin system [PATH:ko04614]
|
|
Circulatory system
|
04260 Cardiac muscle contraction [PATH:ko04260]
|
04270 Vascular smooth muscle contraction [PATH:ko04270]
|
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K09821 AGT; angiotensinogen
K04166 AGTR1; angiotensin II receptor type 1
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K04197 EDNRA; endothelin receptor type A
K05242 AVP; arginine vasopressin
K04226 AVPR1A; arginine vasopressin receptor 1A
K04227 AVPR1B; arginine vasopressin receptor 1B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6, IPLA2; calcium-independent phospholipase A2 [EC:3.1.1.4]
K07425 CYP4A; cytochrome P450, family 4, subfamily A [EC:1.14.15.3]
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05274 KCNMA3; potassium large conductance calcium-activated channel subfamily M alpha member 3
K04937 KCNMB1; potassium large conductance calcium-activated channel subfamily M beta member 1
K04938 KCNMB2; potassium large conductance calcium-activated channel subfamily M beta member 2
K04939 KCNMB3; potassium large conductance calcium-activated channel subfamily M beta member 3
K04941 KCNMB4; potassium large conductance calcium-activated channel subfamily M beta member 4
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K02183 CALM; calmodulin
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K12751 MYL6; myosin light chain 6
K12755 MYL9; myosin regulatory light chain 9
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K06068 NPKC; novel protein kinase C [EC:2.7.11.13]
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K12327 CALD1; caldesmon
K12313 ACTA2; actin, aortic smooth muscle
K12315 ACTG2; actin, gamma-enteric smooth muscle
K12328 PPP1R14A; protein phosphatase 1 regulatory subunit 14A
K06269 PPP1C; protein phosphatase 1, catalytic subunit [EC:3.1.3.16]
K06270 PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
K12329 PPP1R12B; protein phosphatase 1 regulatory subunit 12B
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK; Rho-associated protein kinase [EC:2.7.11.1]
K04266 ADORA2A; adenosine receptor A2a
K04267 ADORA2B; adenosine receptor A2b
K04263 PTGIR; prostacyclin receptor
K12332 CALCA; calcitonin
K12333 ADM; adrenomedullin
K04577 CALCRL; calcitonin receptor-like
K08447 RAMP1; receptor activity modifying protein 1
K08448 RAMP2; receptor activity modifying protein 2
K08449 RAMP3; receptor activity modifying protein 3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12323 ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12336 NPPC; natriuretic peptide C
K12324 ANPRB, NPR2; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K12337 MRVI1, IRAG; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
|
|
Digestive system
|
04970 Salivary secretion [PATH:ko04970]
|
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13504 VAMP2; vesicle-associated membrane protein 2
K04135 ADRA1A; adrenergic receptor alpha-1A
K04136 ADRA1B; adrenergic receptor alpha-1B
K04137 ADRA1D; adrenergic receptor alpha-1D
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04963 RYR3; ryanodine receptor 3
K02183 CALM; calmodulin
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K01242 CD38_157; NAD+ nucleosidase [EC:3.2.2.5]
K13879 BEST2, VMD2L1; bestrophin-2
K09867 AQP5; aquaporin-5
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K10951 SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
K04945 KCNN4; potassium intermediate/small conductance calcium-activated channel subfamily N member 4
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K13855 SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K04975 TRPV6; transient receptor potential cation channel subfamily V member 6
K13908 MUC5B, MG1; mucin-5B
K13909 MUC7, MG2; mucin-7
K13910 PRH1_2; salivary acidic proline-rich phosphoprotein 1/2
K13911 PRB1_2; basic salivary proline-rich protein 1/2
K13912 DMBT1; deleted in malignant brain tumors 1 protein
K13897 CST1; cystatin-SN
K13898 CST2; cystatin-SA
K13899 CST3; cystatin-C
K13900 CST4; cystatin-S
K13901 CST5; cystatin-D
K13913 HTN; histatin
K13914 STATH; statherin
K13915 LYZ; lysozyme C [EC:3.2.1.17]
K12550 LPO; lactoperoxidase [EC:1.11.1.7]
K13916 CAMP, LL37; cathelicidin antimicrobial peptide
|
04971 Gastric acid secretion [PATH:ko04971]
|
K04131 CHRM3; muscarinic acetylcholine receptor M3
K13768 GAST; gastrin
K04195 CCKBR; cholecystokinin B receptor
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K08007 VIL2; villin 2 (ezrin)
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
K04150 HRH2; histamine receptor H2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05237 SST; somatostatin
K04218 SSTR2; somatostatin receptor 2
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04345 PKA; protein kinase A [EC:2.7.11.11]
K01542 ATP4A; H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10]
K01543 ATP4B; H+/K+-exchanging ATPase beta polypeptide [EC:3.6.3.10]
K04896 KCNE2; potassium voltage-gated channel Isk-related subfamily E member 2
K04926 KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
K04995 KCNJ1; potassium inwardly-rectifying channel subfamily J member 1
K04996 KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
K05003 KCNJ10; potassium inwardly-rectifying channel subfamily J member 10
K05008 KCNJ15; potassium inwardly-rectifying channel subfamily J member 15
K05009 KCNJ16; potassium inwardly-rectifying channel subfamily J member 16
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
K04913 KCNK2; potassium channel subfamily K member 2
K04920 KCNK10; potassium channel subfamily K member 10
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K13961 SLC9A4, NHE4; solute carrier family 9 (sodium/hydrogen exchanger), member 4
K13962 SLC26A7, SUT2; solute carrier family 26 (anion exchange transporter), member 7
K13855 SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
|
04972 Pancreatic secretion [PATH:ko04972]
|
K04131 CHRM3; muscarinic acetylcholine receptor M3
K05226 CCK; cholecystokinin
K04194 CCKAR; cholecystokinin A receptor
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K07884 RAB3D; Ras-related protein Rab-3D
K07901 RAB8A, MEL; Ras-related protein Rab-8A
K07904 RAB11A; Ras-related protein Rab-11A
K07886 RAB27B; Ras-related protein Rab-27B
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04513 RHOA; Ras homolog gene family, member A
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K01312 PRSS; trypsin [EC:3.4.21.4]
K09632 CTRL; chymotrypsin-like protease [EC:3.4.21.-]
K01346 CELA2; pancreatic elastase II [EC:3.4.21.71]
K01345 CELA3; pancreatic endopeptidase E [EC:3.4.21.70]
K08779 CPA1; carboxypeptidase A1 [EC:3.4.17.1]
K01298 CPA2; carboxypeptidase A2 [EC:3.4.17.15]
K08780 CPA3; carboxypeptidase A3 [EC:3.4.17.1]
K01291 CPB1; carboxypeptidase B [EC:3.4.17.2]
K01300 CPB2; carboxypeptidase B2 [EC:3.4.17.20]
K14073 PNLIP, PL; pancreatic triacylglycerol lipase [EC:3.1.1.3]
K14074 PNLIPRP1, PLRP1; pancreatic lipase-related protein 1 [EC:3.1.1.3]
K14075 PNLIPRP2, PLRP2; pancreatic lipase-related protein 2 [EC:3.1.1.3]
K12298 CEL; bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
K01047 PLA2G, SPLA2; secretory phospholipase A2 [EC:3.1.1.4]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04962 RYR2; ryanodine receptor 2
K01242 CD38_157; NAD+ nucleosidase [EC:3.2.2.5]
K14077 TPCN2; two pore calcium channel protein 2
K05853 ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
K05027 CLCA1; calcium-activated chloride channel regulator 1
K05028 CLCA2; calcium-activated chloride channel regulator 2
K05030 CLCA4; calcium-activated chloride channel regulator 4
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K10951 SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K04926 KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
K04936 KCNMA1; potassium large conductance calcium-activated channel subfamily M alpha member 1
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K13855 SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
K05263 SCT; secretin
K04588 SCTR; secretin receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
K14078 SLC26A3, DRA; solute carrier family 26 (chloride anion exchanger), member 3
K13575 SLC4A4, NBC1; solute carrier family 4 (sodium bicarbonate cotransporter), member 4
|
04976 Bile secretion [PATH:ko04976]
|
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K03460 SLCO1A; solute carrier organic anion transporter family, member 1A
K05043 SLCO1B; solute carrier organic anion transporter family, member 1B
K14341 SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1
K08204 SLC22A7, OAT2; MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 7
K08205 SLC22A8, OAT3; MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 8
K08198 SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
K00021 E1.1.1.34; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K13885 SCARB1; scavenger receptor class B, member 1
K12473 LDLR; low-density lipoprotein receptor
K14349 NCEH1, AADACL1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K00489 CYP7A1; cytochrome P450, family 7, subfamily A (cholesterol 7alpha-monooxygenase) [EC:1.14.13.17]
K08537 NR1H4, FXR; farnesoid X receptor
K08524 NR2B1, RXRA; retinoid X receptor alpha
K08563 NR0B2, SHP; nuclear receptor subfamily 0 group B member 2
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K08748 SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K00659 BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K09877 AQP9; aquaporin-9
K09869 AQP8; aquaporin-8
K05683 ABCG5; ATP-binding cassette, subfamily G (WHITE), member 5 (sterolin 1)
K05684 ABCG8; ATP-binding cassette, subfamily G (WHITE), member 8 (sterolin 2)
K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2
K13855 SLC4A2, AE2; solute carrier family 4 (anion exchanger), member 2
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1
K05659 ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
K05742 SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
K13857 SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5
K05667 ABCC3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3
K05673 ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
K14360 OSTALPHA, OSTA, SLC51A1; organic solute transporter subunit alpha
K14361 OSTBETA, OSTB, SLC51A2; organic solute transporter subunit beta
K04943 KCNN2; potassium intermediate/small conductance calcium-activated channel subfamily N member 2
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K04588 SCTR; secretin receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
K13575 SLC4A4, NBC1; solute carrier family 4 (sodium bicarbonate cotransporter), member 4
K09866 AQP4; aquaporin-4
K09864 AQP1; aquaporin-1
K14342 SLC10A2, ASBT; solute carrier family 10 (sodium/bile acid cotransporter), member 2
K14158 SLC5A1, SGLT1; solute carrier family 5 (sodium/glucose cotransporter), member 1
K12040 SLC9A3, NHE3; solute carrier family 9 (sodium/hydrogen exchanger), member 3
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
|
04973 Carbohydrate digestion and absorption [PATH:ko04973]
|
04974 Protein digestion and absorption [PATH:ko04974]
|
04975 Fat digestion and absorption [PATH:ko04975]
|
04977 Vitamin digestion and absorption [PATH:ko04977]
|
04978 Mineral absorption [PATH:ko04978]
|
|
Excretory system
|
04962 Vasopressin-regulated water reabsorption [PATH:ko04962]
|
K05242 AVP; arginine vasopressin
K04228 AVPR2; arginine vasopressin receptor 2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K12462 ARHGDI, RHOGDI; Rho GDP-dissociation inhibitor
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09865 AQP2; aquaporin-2
K07904 RAB11A; Ras-related protein Rab-11A
K07905 RAB11B; Ras-related protein Rab-11B
K10413 DYNC1H; dynein heavy chain 1, cytosolic
K10414 DYNC2H, DNCH2; dynein heavy chain 2, cytosolic
K10415 DYNC1I, DNCI; dynein intermediate chain, cytosolic
K10416 DYNC1LI, DNCLI; dynein light intermediate chain 1, cytosolic
K10417 DYNC2LI; dynein light intermediate chain 2, cytosolic
K10418 DYNLL; dynein light chain LC8-type
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K13504 VAMP2; vesicle-associated membrane protein 2
K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
K13502 STX4; syntaxin 4
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K09866 AQP4; aquaporin-4
K09876 AQP3; aquaporin-3
|
04960 Aldosterone-regulated sodium reabsorption [PATH:ko04960]
|
04961 Endocrine and other factor-regulated calcium reabsorption [PATH:ko04961]
|
K04585 PTHR1; parathyroid hormone receptor 1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08539 NR1I1, VDR; vitamin D3 receptor
K08550 NR3A1, ESR1; estrogen receptor alpha
K04974 TRPV5; transient receptor potential cation channel subfamily V member 5
K14756 KL; klotho [EC:3.2.1.31]
K01528 DNM; dynamin GTPase [EC:3.6.5.5]
K11824 AP2A; AP-2 complex subunit alpha
K11825 AP2B1; AP-2 complex subunit beta-1
K11826 AP2M1; AP-2 complex subunit mu-1
K11827 AP2S1; AP-2 complex subunit sigma-1
K04644 CLTA, LCA; clathrin light chain A
K04645 CLTB, LCB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K07904 RAB11A; Ras-related protein Rab-11A
K14757 CALB1, CALB; calbindin D28
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01538 FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
K01325 KLK1_2; tissue kallikrein [EC:3.4.21.35]
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
|
04964 Proximal tubule bicarbonate reclamation [PATH:ko04964]
|
04966 Collecting duct acid secretion [PATH:ko04966]
|
|
Nervous system
|
04724 Glutamatergic synapse [PATH:ko04724]
|
K14990 SLC38A1, SNAT1, GLNT; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1
K14207 SLC38A2, SNAT2; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K05201 GRIK1; glutamate receptor, ionotropic kainate 1
K05202 GRIK2; glutamate receptor, ionotropic kainate 2
K05203 GRIK3; glutamate receptor, ionotropic kainate 3
K05204 GRIK4; glutamate receptor, ionotropic kainate 4
K05205 GRIK5; glutamate receptor, ionotropic kainate 5
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K05213 GRIN3A; glutamate receptor ionotropic, NMDA 3A
K05214 GRIN3B; glutamate receptor ionotropic, NMDA 3B
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K11828 DLG4, PSD95; discs large protein 4
K15008 DLGAP1, GKAP; discs, large-associated protein 1
K15009 SHANK; SH3 and multiple ankyrin repeat domains protein
K04964 TRPC1; transient receptor potential cation channel subfamily C member 1
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K15010 HOMER; homer
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04605 GRM2_3; metabotropic glutamate receptor 2/3
K04607 GRM4; metabotropic glutamate receptor 4
K04608 GRM6_7_8; metabotropic glutamate receptor 6/7/8
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K05613 SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
K05618 SLC1A7, EAAT5; solute carrier family 1 (glutamate transporter), member 7
K05612 SLC1A1, EAAT3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1
K05617 SLC1A6, EAAT4; solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K05614 SLC1A3, EAAT1; solute carrier family 1 (glial high affinity glutamate transporter), member 3
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K13576 SLC38A3, SNAT3; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3
|
04727 GABAergic synapse [PATH:ko04727]
|
K14990 SLC38A1, SNAT1, GLNT; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1
K14207 SLC38A2, SNAT2; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2
K01425 glsA, GLS; glutaminase [EC:3.5.1.2]
K01580 E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
K15015 SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K13524 ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05186 GABRG; gmma-aminobutyric acid receptor subunit gamma
K05184 GABRD; gamma-aminobutyric acid receptor subunit delta
K05185 GABRE; gamma-aminobutyric acid receptor subunit epsilon
K05192 GABRQ; gamma-aminobutyric acid receptor subunit theta
K05189 GABRP; gamma-aminobutyric acid receptor subunit pi
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04647 HAP1; huntingtin-associated protein 1
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein (autophagy-related protein 8)
K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
K15374 TRAK2, GRIF1; trafficking kinesin-binding protein 2
K15375 PLCL1, PRIP; inactive phospholipase C-like protein 1
K15376 GPHN; gephyrin [EC:2.10.1.1 2.7.7.75]
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05034 SLC6A1; solute carrier family 6 (neurotransmitter transporter, GABA) member 1
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K13576 SLC38A3, SNAT3; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3
K14992 SLC38A5, SNAT5; solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5
|
04725 Cholinergic synapse [PATH:ko04725]
|
K00623 CHAT; choline O-acetyltransferase [EC:2.3.1.6]
K01049 ACHE; acetylcholinesterase [EC:3.1.1.7]
K14636 SLC18A3, VACHT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular acetylcholine transporter), member 3
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04131 CHRM3; muscarinic acetylcholine receptor M3
K04133 CHRM5; muscarinic acetylcholine receptor M5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04926 KCNQ1; potassium voltage-gated channel KQT-like subfamily member 1
K04927 KCNQ2; potassium voltage-gated channel KQT-like subfamily member 2
K04928 KCNQ3; potassium voltage-gated channel KQT-like subfamily member 3
K04929 KCNQ4; potassium voltage-gated channel KQT-like subfamily member 4
K04930 KCNQ5; potassium voltage-gated channel KQT-like subfamily member 5
K04996 KCNJ2; potassium inwardly-rectifying channel subfamily J member 2
K05005 KCNJ12; potassium inwardly-rectifying channel subfamily J member 12
K04998 KCNJ4; potassium inwardly-rectifying channel subfamily J member 4
K05007 KCNJ14; potassium inwardly-rectifying channel subfamily J member 14
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04132 CHRM4; muscarinic acetylcholine receptor M4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K04806 CHRNA4; nicotinic acetylcholine receptor alpha-4
K04813 CHRNB2; nicotinic acetylcholine receptor beta-2
K04805 CHRNA3; nicotinic acetylcholine receptor alpha-3
K04815 CHRNB4; nicotinic acetylcholine receptor beta-4
K04808 CHRNA6; nicotinic acetylcholine receptor alpha-6
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator BCL-2
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K14387 SLC5A7, CHT1; solute carrier family 5 (high affinity choline transporter), member 7
|
04728 Dopaminergic synapse [PATH:ko04728]
|
04726 Serotonergic synapse [PATH:ko04726]
|
04720 Long-term potentiation [PATH:ko04720]
|
04730 Long-term depression [PATH:ko04730]
|
04723 Retrograde endocannabinoid signaling [PATH:ko04723]
|
K12302 SLC17A6_7_8; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K13985 NAPEPLD; N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D [EC:3.1.4.54]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13700 ABHD6; abhydrolase domain-containing protein 6 [EC:3.1.1.23]
K15528 FAAH; fatty acid amide hydrolase [EC:3.5.1.99]
K04277 CNR1; cannabinoid receptor 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
K15015 SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K15291 RIMS1, RIM1; regulating synaptic membrane exocytosis protein 1
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05186 GABRG; gmma-aminobutyric acid receptor subunit gamma
K05184 GABRD; gamma-aminobutyric acid receptor subunit delta
K05185 GABRE; gamma-aminobutyric acid receptor subunit epsilon
K05192 GABRQ; gamma-aminobutyric acid receptor subunit theta
K05189 GABRP; gamma-aminobutyric acid receptor subunit pi
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
|
04721 Synaptic vesicle cycle [PATH:ko04721]
|
04722 Neurotrophin signaling pathway [PATH:ko04722]
|
|
Sensory system
|
04744 Phototransduction [PATH:ko04744]
|
04745 Phototransduction - fly [PATH:ko04745]
|
04740 Olfactory transduction [PATH:ko04740]
|
04742 Taste transduction [PATH:ko04742]
|
K04824 SCNN1A; amiloride-sensitive sodium channel subunit alpha
K04825 SCNN1B; amiloride-sensitive sodium channel subunit beta
K04827 SCNN1G; amiloride-sensitive sodium channel subunit gamma
K04828 ASIC2, ACCN1, BNAC1; acid-sensing ion channel 2
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04607 GRM4; metabotropic glutamate receptor 4
K04624 TAS1R1; taste receptor type 1 member 1
K04626 TAS1R3; taste receptor type 1 member 3
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K08474 TAS2R; taste receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04980 TRPM5; transient receptor potential cation channel subfamily M member 5
K04625 TAS1R2; taste receptor type 1 member 2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04885 KCNB1; potassium voltage-gated channel Shab-related subfamily B member 1
|
|
Development
|
|
Environmental adaptation
|
04710 Circadian rhythm [PATH:ko04710]
|
04713 Circadian entrainment [PATH:ko04713]
|
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K05211 GRIN2C; glutamate receptor ionotropic, NMDA 2C
K05212 GRIN2D; glutamate receptor ionotropic, NMDA 2D
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K13240 NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
K04371 ERK1_2; extracellular signal-regulated kinase 1/2 [EC:2.7.11.24]
K04445 MSK1, RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04961 RYR1; ryanodine receptor 1
K04962 RYR2; ryanodine receptor 2
K04963 RYR3; ryanodine receptor 3
K16513 NOS1AP, CAPON; carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K05197 GRIA1; glutamate receptor 1
K05198 GRIA2; glutamate receptor 2
K05199 GRIA3; glutamate receptor 3
K05200 GRIA4; glutamate receptor 4
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04587 ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K07376 PRKG; protein kinase, cGMP-dependent [EC:2.7.11.12]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04286 MTNR1B; melatonin receptor type 1B
K04285 MTNR1A; melatonin receptor type 1A
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K02633 PER; period circadian protein
K04379 FOS; proto-oncogene protein c-fos
|
04711 Circadian rhythm - fly [PATH:ko04711]
|
04712 Circadian rhythm - plant [PATH:ko04712]
|
04626 Plant-pathogen interaction [PATH:ko04626]
|
|
Human Diseases
|
|
Cancers
|
|
Immune diseases
|
|
Neurodegenerative diseases
|
|
Substance dependence
|
05030 Cocaine addiction [PATH:ko05030]
|
05031 Amphetamine addiction [PATH:ko05031]
|
05032 Morphine addiction [PATH:ko05032]
|
K04215 OPRM1; mu-type opioid receptor
K04144 DRD1; dopamine receptor D1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K15015 SLC32A, VGAT; solute carrier family 32 (vesicular inhibitory amino acid transporter)
K04997 KCNJ3; potassium inwardly-rectifying channel subfamily J member 3
K05000 KCNJ6; potassium inwardly-rectifying channel subfamily J member 6
K05002 KCNJ9; potassium inwardly-rectifying channel subfamily J member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K05175 GABRA; gamma-aminobutyric acid receptor subunit alpha
K05181 GABRB; gamma-aminobutyric acid receptor subunit beta
K05186 GABRG; gmma-aminobutyric acid receptor subunit gamma
K05184 GABRD; gamma-aminobutyric acid receptor subunit delta
K05185 GABRE; gamma-aminobutyric acid receptor subunit epsilon
K05192 GABRQ; gamma-aminobutyric acid receptor subunit theta
K05189 GABRP; gamma-aminobutyric acid receptor subunit pi
K05190 GABRR; gamma-aminobutyric acid receptor subunit rho
K04615 GABBR; gamma-aminobutyric acid type B receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K00910 ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
K04439 ARRB; beta-arrestin
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13296 PDE3; cGMP-inhibited 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01120 PDE; 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17]
K04265 ADORA1; adenosine A1 receptor
|
05033 Nicotine addiction [PATH:ko05033]
|
05034 Alcoholism [PATH:ko05034]
|
|
Cardiovascular diseases
|
05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
|
05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
|
05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
|
K06480 ITGA1; integrin alpha 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K06485 ITGA6; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K06493 ITGB3; integrin beta 3
K06525 ITGB4; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K12563 SGCD; delta-sarcoglycan
K12564 SGCG; gamma-sarcoglycan
K12565 SGCA; alpha-sarcoglycan
K12566 SGCB; beta-sarcoglycan
K06265 DAG1; dystroglycan 1
K07610 DES; desmin
K10366 DMD; dystrophin
K05692 ACTB_G1; actin beta/gamma 1
K12567 TTN; titin [EC:2.7.11.1]
K12045 TNNT2; troponin T, cardiac muscle
K05865 TNNC1; troponin C, slow skeletal and cardiac muscles
K12044 TNNI3; troponin I, cardiac muscle
K12314 ACTC1; actin, alpha cardiac muscle
K10373 TPM1; tropomyosin 1
K10374 TPM2; tropomyosin 2
K09290 TPM3; tropomyosin 3
K10375 TPM4; tropomyosin 4
K12568 MYBPC3; myosin-binding protein C, cardiac-type
K12749 MYL3; myosin light chain 3
K10351 MYL2; myosin regulatory light chain 2
K12569 EMD; emerin
K12641 LMNA; lamin A/C
K06856 IGH; immunoglobulin heavy chain
K04141 ADRB1; adrenergic receptor beta-1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04862 CACNB1; voltage-dependent calcium channel beta-1
K04863 CACNB2; voltage-dependent calcium channel beta-2
K04864 CACNB3; voltage-dependent calcium channel beta-3
K04865 CACNB4; voltage-dependent calcium channel beta-4
K04858 CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
K04859 CACNA2D2; voltage-dependent calcium channel alpha-2/delta-2
K04860 CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
K04861 CACNA2D4; voltage-dependent calcium channel alpha-2/delta-4
K04866 CACNG1; voltage-dependent calcium channel gamma-1
K04867 CACNG2; voltage-dependent calcium channel gamma-2
K04868 CACNG3; voltage-dependent calcium channel gamma-3
K04869 CACNG4; voltage-dependent calcium channel gamma-4
K04870 CACNG5; voltage-dependent calcium channel gamma-5
K04871 CACNG6; voltage-dependent calcium channel gamma-6
K04872 CACNG7; voltage-dependent calcium channel gamma-7
K04873 CACNG8; voltage-dependent calcium channel gamma-8
K04962 RYR2; ryanodine receptor 2
K05852 PLN; phospholamban
K05459 IGF1; insulin-like growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03156 TNFA; tumor necrosis factor superfamily, member 2
|
05416 Viral myocarditis [PATH:ko05416]
|
|
Endocrine and metabolic diseases
|
|
Infectious diseases
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
05166 HTLV-I infection [PATH:ko05166]
|
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1; neuropilin 1
K06527 VCAM1; vascular cell adhesion molecule 1
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06490 ICAM1; intercellular adhesion molecule 1
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K06271 TLN; talin
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; cyclin D2
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K06751 MHC1; major histocompatibility complex, class I
K08057 CALR; calreticulin
K04348 PPP3C, CNA; protein phosphatase 3, catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; protein phosphatase 3, regulatory subunit
K04446 NFATC, NFAT; nuclear factor of activated T-cells, cytoplasmic
K08054 CANX; calnexin
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 BZRP; benzodiazapine receptor
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03356 APC9; anaphase-promoting complex subunit 9
K03357 APC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12416 SWM1, APC13; anaphase-promoting complex subunit SWM1
K06635 PTTG; securin
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K04802 PCNA; proliferating cell nuclear antigen
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE1; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04503 CCND1; cyclin D1
K10152 CCND3; cyclin D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K06620 E2F1_3; E2F transcription factor 1/3
K09389 E2F2; E2F transcription factor 2
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K04690 FZDN, fz3; frizzled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K12076 DLG1; disks large protein 1
K04359 PDGFA_B; platelet derived growth factor A/B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03156 TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K15307 GPS2; G protein pathway suppressor 2
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
K15308 TTP; tristetraprolin
K08065 NFYB; nuclear transcription Y subunit beta
K06752 MHC2; major histocompatibility complex, class II
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS, pnt; c-ets proto-oncogene protein
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K12496 EGR2; early growth response protein 2
K04502 FOSL1; fos-like antigen 1
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09052 CREM; cAMP response element modulator
K09053 ATF1; activating transcription factor 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K09032 ATF3, LRF1; activating transcription factor 3
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09027 XBP1; X box-binding protein 1
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09420 MYB; myb proto-oncogene protein
K09421 MYBL; myb-related protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04728 ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
K06641 CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02159 BAX; apoptosis regulator BAX
K15310 TP53INP1; tumor protein p53-inducible nuclear protein 1
K09341 MSX; homeobox protein MSX
|
05162 Measles [PATH:ko05162]
|
05164 Influenza A [PATH:ko05164]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
05168 Herpes simplex infection [PATH:ko05168]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05146 Amoebiasis [PATH:ko05146]
|
05144 Malaria [PATH:ko05144]
|
05145 Toxoplasmosis [PATH:ko05145]
|
05140 Leishmaniasis [PATH:ko05140]
|
05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
|
05143 African trypanosomiasis [PATH:ko05143]
|
KEGG Orthology (KO)