KEGG Orthology (KO)

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   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:ko04911]
     04910 Insulin signaling pathway [PATH:ko04910]
     04920 Adipocytokine signaling pathway [PATH:ko04920]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K03173  TRAF2; TNF receptor-associated factor 2
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K05872  NFKBIE; NF-kappa-B inhibitor epsilon
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K17445  IRS3; insulin receptor substrate 3
       K17446  IRS4; insulin receptor substrate 4
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K06259  CD36; CD36 antigen
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K05228  POMC; proopiomelanocortin
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K05231  AGRP; agouti related protein
       K05232  NPY; neuropeptide Y
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K01084  G6PC; glucose-6-phosphatase [EC:3.1.3.9]
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07298  STK11, LKB1; serine/threonine-protein kinase 11
       K07359  CAMKK; calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K07191  SLC2A4, GLUT4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
     03320 PPAR signaling pathway [PATH:ko03320]
       K06259  CD36; CD36 antigen
       K08745  SLC27A1_4, FATP1, FATP4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
       K08746  SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
       K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
       K08749  SLC27A6, FATP6; solute carrier family 27 (fatty acid transporter), member 6
       K08750  FABP1, L-FABP; fatty acid-binding protein 1, liver
       K08751  FABP2; fatty acid-binding protein 2, intestinal
       K08752  FABP3; fatty acid-binding protein 3, muscle and heart
       K08753  FABP4, aP2; fatty acid-binding protein 4, adipocyte
       K08754  FABP5; fatty acid-binding protein 5, epidermal
       K08755  FABP6; fatty acid-binding protein 6, ileal (gastrotropin)
       K08756  FABP7; fatty acid-binding protein 7, brain
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08757  APOA1; apolipoprotein A-I
       K08758  APOA2; apolipoprotein A-II
       K08759  APOC3; apolipoprotein C-III
       K09025  APOA5; apolipoprotein A-V
       K08761  PLTP; phospholipid transfer protein
       K10226  FADS2; fatty acid desaturase 2 (delta-6 desaturase) [EC:1.14.19.-]
       K00507  SCD, desC; stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1]
       K00489  CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.13.17]
       K07431  CYP8B1; sterol 12-alpha-hydroxylase [EC:1.14.13.95 1.14.13.96]
       K08536  NR1H3, LXRA; liver X receptor alpha
       K00488  CYP27A; cholestanetriol 26-monooxygenase [EC:1.14.13.15]
       K08762  DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
       K01059  LPL; lipoprotein lipase [EC:3.1.1.34]
       K01897  ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]
       K15013  ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
       K08763  OLR1; oxidised low-density lipoprotein receptor 1
       K07514  EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
       K07425  CYP4A; alkane 1-monooxygenase [EC:1.14.15.3]
       K07513  ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
       K08764  SCP2, SCPX; sterol carrier protein 2 [EC:2.3.1.176]
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K10214  ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
       K08765  CPT1; carnitine O-palmitoyltransferase 1 [EC:2.3.1.21]
       K08766  CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
       K00255  ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
       K00249  ACADM, acd; acyl-CoA dehydrogenase [EC:1.3.8.7]
       K08767  ANGPTL4, PGAR; angiopoietin-like 4
       K06086  SORBS1, SH3D5, PONSIN, CAP; sorbin and SH3 domain containing 1
       K08768  PLIN; perilipin
       K07296  ACDC; adiponectin
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K08769  UCP1, SLC25A7; solute carrier family 25 (mitochondrial uncoupling protein), member 7
       K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K08770  UBC; ubiquitin C
       K01596  E4.1.1.32, pckA, PEPCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
       K00864  glpK, GK; glycerol kinase [EC:2.7.1.30]
       K08771  AQP7; aquaporin-7
     04912 GnRH signaling pathway [PATH:ko04912]
     04913 Ovarian Steroidogenesis [PATH:ko04913]
     04915 Estrogen signaling pathway [PATH:ko04915]
     04914 Progesterone-mediated oocyte maturation [PATH:ko04914]
     04917 Prolactin signaling pathway [PATH:ko04917]
     04921 Oxytocin signaling pathway [PATH:ko04921]
     04918 Thyroid hormone synthesis [PATH:ko04918]
     04919 Thyroid hormone signaling pathway [PATH:ko04919]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K06487  ITGAV; integrin alpha V
       K06493  ITGB3; integrin beta 3
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K11220  STAT1; signal transducer and activator of transcription 1
       K04451  TP53, P53; tumor protein p53
       K08550  NR3A1, ESR1; estrogen receptor alpha
       K08362  NR1A2, THRB; thyroid hormone receptor beta
       K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
       K11644  SIN3A; paired amphipathic helix protein Sin3a
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K11404  HDAC3; histone deacetylase 3 [EC:3.5.1.98]
       K05547  NR1A1, THRA; thyroid hormone receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K06062  PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
       K09101  NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
       K11255  NCOA2, TIF2, KAT13C; nuclear receptor coactivator 2
       K11256  NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K15146  MED4; mediator of RNA polymerase II transcription subunit 4
       K15162  MED12; mediator of RNA polymerase II transcription subunit 12
       K15164  MED13; mediator of RNA polymerase II transcription subunit 13
       K15156  MED14, RGR1; mediator of RNA polymerase II transcription subunit 14
       K15159  MED16; mediator of RNA polymerase II transcription subunit 16
       K15133  MED17; mediator of RNA polymerase II transcription subunit 17
       K15167  MED24; mediator of RNA polymerase II transcription subunit 24
       K15170  MED27; mediator of RNA polymerase II transcription subunit 27
       K15143  MED30; mediator of RNA polymerase II transcription subunit 30
       K15144  MED1; mediator of RNA polymerase II transcription subunit 1
       K04503  CCND1; cyclin D1
       K09183  GATA4; GATA-binding protein 4
       K17901  RCAN1, MCIP1; calcipressin-1
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K04377  MYC; Myc proto-oncogene protein
       K05852  PLN; phospholamban
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K02105  CTNNB1; catenin beta 1
       K02599  NOTCH; Notch
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05857  PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K01114  plcC; phospholipase C [EC:3.1.4.3]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
       K01540  ATP1B; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K08231  SLC16A2; MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 2
       K08187  SLC16A10; MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K07207  TSC2; tuberous sclerosis 2
       K07208  RHEB; Ras homolog enriched in brain
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K17902  TBC1D4, AS160; TBC1 domain family member 4
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K17903  RCAN2, ZAKI4; calcipressin-2
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K08747  SLCO1C; solute carrier organic anion transporter family, member 1C
       K01562  DIO1; type I thyroxine 5'-deiodinase [EC:1.97.1.10]
       K17904  DIO2; type II thyroxine 5'-deiodinase [EC:1.97.1.10]
       K07754  DIO3; thyroxine 5-deiodinase [EC:1.97.1.11]
       K05692  ACTB_G1; actin beta/gamma 1
     04916 Melanogenesis [PATH:ko04916]
     04614 Renin-angiotensin system [PATH:ko04614]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Environmental adaptation
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K02353  DVL; segment polarity protein dishevelled
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator BCL-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04358  FGF; fibroblast growth factor
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04513  RHOA; Ras homolog gene family, member A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05405  IL6; interleukin 6
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04496  CTBP; C-terminal binding protein
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K02159  BAX; apoptosis regulator BAX
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03868  RBX1, ROC1; RING-box protein 1
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06227  COS2; costal 2
       K06228  FU; fused [EC:2.7.11.1]
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K04662  BMP2_4; bone morphogenetic protein 2/4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  NR3C4, AR; androgen receptor
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K10789  MPO; myeloperoxidase [EC:1.11.2.2]
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04736  IL3; interleukin 3
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K11644  SIN3A; paired amphipathic helix protein Sin3a
       K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K09438  SPI1; transcription factor PU.1
       K04391  CD14; CD14 antigen
       K06461  ITGAM; integrin alpha M
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K10056  JUP; junction plakoglobin
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K10051  CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
       K02162  BCL2A1; hematopoietic BCL2-related protein A1
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K04377  MYC; Myc proto-oncogene protein
       K09063  TCF3, E2A; transcription factor E2-alpha
       K09355  PBX1; pre-B-cell leukemia transcription factor 1
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K03211  ETV6_7, yan; ETS translocation variant 6/7
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K01327  ELANE; leukocyte elastase [EC:3.4.21.37]
       K01353  GZMB; granzyme B [EC:3.4.21.79]
       K09186  MLL1; histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]
       K15184  AFF1; AF4/FMR2 family member 1
       K02211  CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
       K15188  CCNT; cyclin T
       K15187  MLLT1_3, ENL, AF9; YEATS domain-containing protein 1/3
       K11427  DOT1L, DOT1; histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43]
       K15612  LMO2; rhombotin-2
       K15610  PBX3; pre-B-cell leukemia transcription factor 3
       K09278  RUNX2, AML3; runt-related transcription factor 2
       K04676  SMAD1; mothers against decapentaplegic homolog 1
       K15605  KLF3; krueppel-like factor 3
       K04454  MEF2C; MADS-box transcription enhancer factor 2C
       K11449  JMJD1C; jumonji domain-containing protein 1C [EC:1.14.11.-]
       K09283  HMGA2; high mobility group AT-hook protein 2
       K11447  UTX, UTY; histone demethylase [EC:1.14.11.-]
       K11313  SUPT3H, SPT3; transcription initiation protein SPT3
       K06532  PROM1; prominin 1
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K08854  BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K08821  CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]
       K15613  MEIS1; homeobox protein Meis1
       K15614  SIX1; homeobox protein SIX1
       K15615  SIX4; homeobox protein SIX4
       K15616  EYA1; eyes absent homolog 1 [EC:3.1.3.48]
       K06622  CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
       K00069  HPGD; 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141]
       K05199  GRIA3; glutamate receptor 3
       K00717  FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
       K15607  TLX3, HOX11L2; T-cell leukemia homeobox protein 3
       K09340  TLX1, HOX11; T-cell leukemia homeobox protein 1
       K04182  CCR7; C-C chemokine receptor type 7
       K15617  LDB1; LIM domain-binding protein 1
       K15604  LYL1; protein lyl-1
       K08024  HHEX, HEX, PRH; homeobox protein HEX
       K06056  PTCRA; pre T-cell antigen receptor alpha
       K09254  REL; c-Rel proto-oncogene protein
       K03172  TRAF1; TNF receptor-associated factor 1
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K05413  CD86; CD86 antigen
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K15618  BCL6; B-cell lymphoma 6 protein
       K06856  IGH; immunoglobulin heavy chain
       K09035  CMAF, MAF; transcription factor Maf
       K10151  CCND2; cyclin D2
       K06590  ITGB7; integrin beta 7
       K11424  WHSC1, MMSET, NSD2; histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43]
       K11253  H3; histone H3
       K09383  PAX5; paired box protein 5
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K13105  PRCC; proline-rich protein PRCC
       K09105  TFE3; transcription factor E3
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K09633  TMPRSS2; transmembrane protease, serine 2
       K09435  ERG; transcriptional regulator ERG
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K01343  PLAT; tissue plasminogen activator [EC:3.4.21.68]
       K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K15619  SPINT1; Kunitz-type protease inhibitor 1
       K04387  IL1R2; interleukin 1 receptor type II
       K09431  ETV1; ets translocation variant 1
       K15592  ETV4; ets translocation variant 4
       K15593  ETV5; ets translocation variant 5
       K15379  SLC45A3; solute carrier family 45, member 3
       K04376  ELK4, SAP1; ETS domain-containing protein Elk-4
       K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13]
       K09109  NMYC, MYCN; N-myc proto-oncogene protein
       K04453  MAX; Max protein
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K04451  TP53, P53; tumor protein p53
       K11459  PCGF4, BMI1; polycomb group RING finger protein 4
       K04684  SP1; transcription factor Sp1
       K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K02583  NGFR; nerve growth factor receptor (TNFR superfamily member 16)
       K14970  MEN1, MNN1; menin
       K13209  EWSR1; RNA-binding protein EWS
       K09436  FLI1; friend leukemia integration 1 transcription factor
       K05459  IGF1; insulin-like growth factor 1
       K17693  ID2; DNA-binding protein inhibitor ID2
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K10138  IGFBP3; insulin-like growth factor-binding protein 3
       K09437  FEV; ETS oncogene family protein FEV
       K09053  ATF1; activating transcription factor 1
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K15620  GOLPH3, GPP34; golgi phosphoprotein 3
       K09234  WT1; Wilms tumor protein 1
       K04359  PDGFA; platelet-derived growth factor subunit A
       K05069  IL2RB; interleukin 2 receptor beta
       K15621  BAIAP3; BAI1-associated protein 3
       K06571  TSPAN7, TM4SF2, MXS1; tetraspanin-7
       K15622  MLF1; myeloid leukemia factor 1
       K08559  NR4A3, NOR1; nuclear receptor subfamily 4 group A member 3
       K14651  TAF15; transcription initiation factor TFIID subunit 15
       K13098  TLS, FUS; RNA-binding protein FUS
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K10048  CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
       K05405  IL6; interleukin 6
       K14242  NFKBIZ; NF-kappa-B inhibitor zeta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K10030  IL8, CXCL8; interleukin 8
       K07201  FOXO1; forkhead box protein O1
       K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
       K15623  SS18, SSXT, SYT; protein SSXT
       K15624  SSX1; protein SSX1
       K15625  SSX2; protein SSX2
       K15626  NUPR1, COM1; nuclear protein, 1
       K15627  ASPSCR1, ASPL; tether containing UBX domain for GLUT4
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR; nucleoprotein TPR
       K09292  TFG; protein TFG
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K07827  KRAS, KRAS2; GTPase KRas
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K04451  TP53, P53; tumor protein p53
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K04451  TP53, P53; tumor protein p53
       K02161  BCL2; apoptosis regulator BCL-2
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04377  MYC; Myc proto-oncogene protein
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K04503  CCND1; cyclin D1
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
     05223 Non-small cell lung cancer [PATH:ko05223]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K04503  CCND1; cyclin D1
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K07827  KRAS, KRAS2; GTPase KRas
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02158  BAD; BCL2-antagonist of cell death
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K09408  FOXO3; forkhead box protein O3
       K04357  EGF; epidermal growth factor
       K08774  TGFA; transforming growth factor, alpha
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04451  TP53, P53; tumor protein p53
       K15420  EML4; echinoderm microtubule-associated protein-like 4
       K05119  ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 28, 2014