KEGG Orthology (KO)

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 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
     00190 Oxidative phosphorylation [PATH:ko00190]
     00195 Photosynthesis [PATH:ko00195]
     00196 Photosynthesis - antenna proteins [PATH:ko00196]
     00194 Photosynthesis proteins [BR:ko00194]
     00710 Carbon fixation in photosynthetic organisms [PATH:ko00710]
     00720 Carbon fixation pathways in prokaryotes [PATH:ko00720]
     00680 Methane metabolism [PATH:ko00680]
     00910 Nitrogen metabolism [PATH:ko00910]
     00920 Sulfur metabolism [PATH:ko00920]
       K02048  cysP, sbp; sulfate transport system substrate-binding protein
       K02046  cysU; sulfate transport system permease protein
       K02047  cysW; sulfate transport system permease protein
       K02045  cysA; sulfate transport system ATP-binding protein [EC:3.6.3.25]
       K15551  tauA; taurine transport system substrate-binding protein
       K15552  tauC; taurine transport system permease protein
       K10831  tauB; taurine transport system ATP-binding protein [EC:3.6.3.36]
       K03119  tauD; taurine dioxygenase [EC:1.14.11.17]
       K15553  ssuA; sulfonate transport system substrate-binding protein
       K15554  ssuC; sulfonate transport system permease protein
       K15555  ssuB; sulfonate transport system ATP-binding protein [EC:3.6.3.-]
       K04091  ssuD; alkanesulfonate monooxygenase [EC:1.14.14.5]
       K00299  ssuE; FMN reductase [EC:1.5.1.38]
       K13811  PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
       K00955  cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
       K00956  cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]
       K00957  cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
       K00958  sat, met3; sulfate adenylyltransferase [EC:2.7.7.4]
       K00860  cysC; adenylylsulfate kinase [EC:2.7.1.25]
       K01082  E3.1.3.7, cysQ, MET22, BPNT1; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
       K15759  IMPAD1, IMPA3; inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7]
       K15422  SAL; 3'(2'), 5'-bisphosphate nucleotidase / inositol polyphosphate 1-phosphatase [EC:3.1.3.7 3.1.3.57]
       K00394  aprA; adenylylsulfate reductase, subunit A [EC:1.8.99.2]
       K00395  aprB; adenylylsulfate reductase, subunit B [EC:1.8.99.2]
       K05907  APR; adenylyl-sulfate reductase (glutathione) [EC:1.8.4.9]
       K00390  cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8]
       K00387  SUOX; sulfite oxidase [EC:1.8.3.1]
       K05301  E1.8.2.1; sulfite dehydrogenase [EC:1.8.2.1]
       K17222  soxA1; sulfur-oxidizing protein SoxA
       K17223  soxX; sulfur-oxidizing protein SoxX
       K17226  soxY; sulfur-oxidizing protein SoxY
       K17227  soxZ; sulfur-oxidizing protein SoxZ
       K17224  soxB1; sulfur-oxidizing protein SoxB
       K17225  soxC; sulfane dehydrogenase subunit SoxC
       K08738  CYC; cytochrome c
       K11180  dsrA; sulfite reductase alpha subunit [EC:1.8.99.3 1.8.99.1]
       K11181  dsrB; sulfite reductase beta subunit [EC:1.8.99.3 1.8.99.1]
       K00380  cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]
       K00381  cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]
       K16950  asrA; anaerobic sulfite reductase subunit A
       K16951  asrB; anaerobic sulfite reductase subunit B
       K00385  asrC; anaerobic sulfite reductase subunit C
       K00392  sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]
       K17725  ETHE1; sulfur dioxygenase [EC:1.13.11.18]
       K17229  fccB; sulfide dehydrogenase [flavocytochrome c] flavoprotein chain [EC:1.8.2.3]
       K17230  fccA; cytochrome subunit of sulfide dehydrogenase
       K16952  sor; sulfur oxygenase/reductase [EC:1.13.11.55]
       K17219  sreA; sulfur reductase molybdopterin subunit
       K17220  sreB; sulfur reductase FeS subunit
       K17221  sreC; sulfur reductase membrane anchor
       K16936  doxA; thiosulfate dehydrogenase [quinone] small subunit [EC:1.8.5.2]
       K16937  doxD; thiosulfate dehydrogenase [quinone] large subunit [EC:1.8.5.2]
       K08357  ttrA; tetrathionate reductase subunit A
       K08358  ttrB; tetrathionate reductase subunit B
       K08359  ttrC; tetrathionate reductase subunit C
       K08352  phsA, psrA; thiosulfate reductase / polysulfide reductase chain A
       K08353  phsB; thiosulfate reductase electron transport protein
       K08354  phsC; thiosulfate reductase cytochrome b subunit
       K01011  TST, MPST, sseA; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
       K02439  glpE; thiosulfate sulfurtransferase [EC:2.8.1.1]
       K00640  cysE; serine O-acetyltransferase [EC:2.3.1.30]
       K10150  cysO; cysteine synthase / O-phosphoserine sulfhydrylase / cystathionine beta-synthase [EC:2.5.1.47 2.5.1.65 4.2.1.22]
       K01738  cysK; cysteine synthase A [EC:2.5.1.47]
       K12339  cysM; cysteine synthase B [EC:2.5.1.47]
       K13034  ATCYSC1; L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9]
       K17069  MET17; O-acetylhomoserine/O-acetylserine sulfhydrylase [EC:2.5.1.49 2.5.1.47]
       K00651  metA; homoserine O-succinyltransferase [EC:2.3.1.46]
       K01739  metB; cystathionine gamma-synthase [EC:2.5.1.48]
       K10764  metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]
       K17217  mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
       K17228  sfnG; FMNH2-dependent dimethyl sulfone monooxygenase
       K16968  msmA; methanesulfonate monooxygenase large subunit [EC:1.14.13.111]
       K16969  msmB; methanesulfonate monooxygenase small subunit [EC:1.14.13.111]
       K15762  tmoC, tbuB, touC; toluene monooxygenase system ferredoxin subunit
       K15765  tmoF, tbuC, touF; toluene monooxygenase electron transfer component [EC:1.18.1.3]
       K07306  dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
       K07307  dmsB; anaerobic dimethyl sulfoxide reductase subunit B (DMSO reductase iron- sulfur subunit)
       K07308  dmsC; anaerobic dimethyl sulfoxide reductase subunit C (DMSO reductase anchor subunit)
       K16964  ddhA; dimethylsulfide dehydrogenase subunit alpha [EC:1.8.2.4]
       K16965  ddhB; dimethylsulfide dehydrogenase subunit beta
       K16966  ddhC; dimethylsulfide dehydrogenase subunit gamma
       K16953  dddL; dimethylpropiothetin dethiomethylase [EC:4.4.1.3]
       K17486  dmdA; dimethylsulfoniopropionate demethylase [EC:2.1.1.269]
       K16967  dmoA; dimethyl-sulfide monooxygenase [EC:1.14.13.131]
       K16954  mtsA1, mtsA; methylthiol:coenzyme M methyltransferase [EC:2.1.1.251]
       K16955  mtsB1, mtsB; methylated-thiol--corrinoid protein
       K17218  sqr; sulfide:quinone oxidoreductase [EC:1.8.5.-]
       K17995  hydG; sulfhydrogenase subunit gamma (sulfur reductase) [EC:1.12.98.4]
       K17996  hydB; sulfhydrogenase subunit beta (sulfur reductase) [EC:1.12.98.4]
       K17993  hydA; sulfhydrogenase subunit alpha [EC:1.12.1.3 1.12.1.5]
       K17994  hydD; sulfhydrogenase subunit delta [EC:1.12.1.3 1.12.1.5]
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system [PATH:ko02020]
       K07636  phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
       K07657  phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
       K07658  phoB1, phoP; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
       K01077  E3.1.3.1, phoA, phoB; alkaline phosphatase [EC:3.1.3.1]
       K01113  phoD; alkaline phosphatase D [EC:3.1.3.1]
       K07768  senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]
       K07776  regX3; two-component system, OmpR family, response regulator RegX3
       K02040  pstS; phosphate transport system substrate-binding protein
       K07637  phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
       K07660  phoP; two-component system, OmpR family, response regulator PhoP
       K07804  pagC; putatice virulence related protein PagC
       K07790  pagO; putative membrane protein PagO
       K07805  pagD; putative membrane protein PagD
       K07801  pagK; hypothetical protein PagK
       K08477  pgtE; outer membrane protease E [EC:3.4.21.-]
       K09474  phoN; acid phosphatase (class A) [EC:3.1.3.2]
       K07638  envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
       K07659  ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
       K09475  ompC; outer membrane pore protein C
       K09476  ompF; outer membrane pore protein F
       K07639  rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
       K07661  rstA; two-component system, OmpR family, response regulator RstA
       K07640  cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
       K07662  cpxR; two-component system, OmpR family, response regulator CpxR
       K04771  degP, htrA; serine protease Do [EC:3.4.21.107]
       K07650  cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]
       K07770  cssR; two-component system, OmpR family, response regulator CssR
       K07641  creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
       K07663  creB; two-component system, OmpR family, catabolic regulation response regulator CreB
       K07642  baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
       K07664  baeR, smeR; two-component system, OmpR family, response regulator BaeR
       K07799  mdtA; putative multidrug efflux transporter MdtA
       K07788  mdtB; RND superfamily, multidrug transport protein MdtB
       K07789  mdtC; RND superfamily, multidrug transport protein MdtC
       K18326  mdtD; MFS transporter, DHA2 family, putative multidrug resistance protein MdtD
       K18321  smeA; membrane fusion protein
       K18322  smeB; multidrug efflux pump
       K18323  smeC; outer membrane protein
       K18324  acrD; multidrug efflux pump
       K07643  basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
       K07771  basR; two-component system, OmpR family, response regulator BasR
       K07806  arnB, pmrH; UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC:2.6.1.87]
       K07644  cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
       K07665  cusR, copR, silR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
       K07796  cusC, silC; Cu(I)/Ag(I) efflux system outer membrane protein CusC/SilC
       K07810  cusF; Cu(I)/Ag(I) efflux system periplasmic protein CusF
       K07798  cusB, silB; Cu(I)/Ag(I) efflux system membrane protein CusB/SilB
       K07787  cusA, silA; Cu(I)/Ag(I) efflux system membrane protein CusA/SilA
       K07645  qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
       K07666  qseB; two-component system, OmpR family, response regulator QseB
       K02403  flhD; flagellar transcriptional activator FlhD
       K02402  flhC; flagellar transcriptional activator FlhC
       K02406  fliC; flagellin
       K02405  fliA; RNA polymerase sigma factor for flagellar operon FliA
       K02556  motA; chemotaxis protein MotA
       K07646  kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
       K07667  kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
       K01546  kdpA; K+-transporting ATPase ATPase A chain [EC:3.6.3.12]
       K01547  kdpB; K+-transporting ATPase ATPase B chain [EC:3.6.3.12]
       K01548  kdpC; K+-transporting ATPase ATPase C chain [EC:3.6.3.12]
       K01545  kdpF; K+-transporting ATPase ATPase F chain
       K07647  torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
       K07772  torR; two-component system, OmpR family, torCAD operon response regulator TorR
       K03532  torC; trimethylamine-N-oxide reductase (cytochrome c), cytochrome c-type subunit TorC
       K07811  torA; trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3]
       K03533  torD; TorA specific chaperone
       K07648  arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
       K07773  arcA; two-component system, OmpR family, aerobic respiration control protein ArcA
       K07649  tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
       K07774  tctD; two-component system, OmpR family, response regulator TctD
       K07793  tctA; putative tricarboxylic transport membrane protein
       K07794  tctB; putative tricarboxylic transport membrane protein
       K07795  tctC; putative tricarboxylic transport membrane protein
       K07651  resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
       K07775  resD; two-component system, OmpR family, response regulator ResD
       K02259  COX15; cytochrome c oxidase assembly protein subunit 15
       K07652  vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
       K07668  vicR; two-component system, OmpR family, response regulator VicR
       K00689  E2.4.1.5; dextransucrase [EC:2.4.1.5]
       K00692  sacB; levansucrase [EC:2.4.1.10]
       K07653  mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]
       K07669  mprA; two-component system, OmpR family, response regulator MprA
       K08372  pepD; putative serine protease PepD [EC:3.4.21.-]
       K07654  mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]
       K07670  mtrA; two-component system, OmpR family, response regulator MtrA
       K02313  dnaA; chromosomal replication initiator protein
       K07655  prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]
       K07671  prrA; two-component system, OmpR family, response regulator PrrA
       K07656  trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]
       K07672  trcR; two-component system, OmpR family, response regulator TrcR
       K11328  nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and/or redox sensor kinase NrsS [EC:2.7.13.3]
       K11330  nrsR, rppA; two-component system, OmpR family, Ni(II)-responsive and/or redox-responsive regulator NrsR
       K11327  nrsB; cation efflux system protein involved in nickel and cobalt tolerance
       K11326  nrsA, czcA; cation efflux system protein involved in nickel and cobalt tolerance
       K11331  nrsC; cation efflux system protein involved in nickel and cobalt tolerance [EC:3.2.1.17]
       K07785  nrsD, nreB; MFS transporter, NRE family, putaive nickel resistance protein
       K11520  manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]
       K11521  K11521, manR; two-component system, OmpR family, manganese sensing response regulator
       K11601  mntC; manganese transport system substrate-binding protein
       K11603  mntA; manganese transport system ATP-binding protein
       K11602  mntB; manganese transport system permease protein
       K07769  nblS; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]
       K11332  nblR; two-component system, OmpR family, response regulator NblR
       K08479  sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]
       K10697  rpaA; two-component system, OmpR family, response regulator RpaA
       K11329  rpaB; two-component system, OmpR family, response regulator RpaB
       K10681  saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
       K10682  saeR; two-component system, OmpR family, response regulator SaeR
       K11629  bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]
       K11630  bceR; two-component system, OmpR family, bacitracin resistance response regulator BceR
       K11631  bceA; bacitracin transport system ATP-binding protein
       K11632  bceB; bacitracin transport system permease protein
       K11633  yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]
       K11634  yxdJ; two-component system, OmpR family, response regulator YxdJ
       K11635  yxdL; putative ABC transport system ATP-binding protein
       K11636  yxdM; putative ABC transport system permease protein
       K14980  chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
       K14981  chvI; two-component system, OmpR family, response regulator ChvI
       K14982  ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]
       K14983  ciaR; two-component system, OmpR family, response regulator CiaR
       K15860  ciaX; regulatory peptide CiaX
       K18072  parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]
       K18073  parR; two-component system, OmpR family, response regulator ParR
       K18093  oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
       K18094  mexX, amrA; membrane fusion protein
       K18095  mexY, amrB; multidrug efflux pump
       K18345  vanSB; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18350  vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
       K18344  vanRB; two-component system, OmpR family, response regulator VanR
       K18349  vanRE, vanRG; two-component system, OmpR family, response regulator VanR
       K18352  vanRAc; two-component system, OmpR family, response regulator VanR
       K15739  E6.1.2.1, vanB, vanA, vanG; D-alanine---(R)-lactate ligase [EC:6.1.2.1]
       K18347  vanH; D-specific alpha-keto acid dehydrogenase [EC:1.1.1.-]
       K08641  vanX; D-alanyl-D-alanine dipeptidase [EC:3.4.13.22]
       K18353  vanJ; vancomycin resistance protein VanJ
       K18354  vanK; vancomycin resistance protein VanK
       K18348  vanT; serine/alanine racemase [EC:5.1.1.18 5.1.1.1]
       K07260  vanY; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]
       K18346  vanW; vancomycin resistance protein VanW
       K02491  kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
       K07697  kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]
       K06347  kapB; kinase-associated protein B
       K07698  kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
       K13532  kinD; two-component system, sporulation sensor kinase D [EC:2.7.13.3]
       K13533  kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
       K02490  spo0F; two-component system, response regulator, stage 0 sporulation protein F
       K06375  spo0B; stage 0 sporulation protein B (sporulation initiation phosphotransferase) [EC:2.7.-.-]
       K07699  spo0A; two-component system, response regulator, stage 0 sporulation protein A
       K07700  dpiB, citA; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
       K07702  dpiA, citB; two-component system, CitB family, response regulator CitB
       K01910  citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]
       K01646  citD; citrate lyase subunit gamma (acyl carrier protein)
       K01644  citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
       K01643  citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10]
       K05964  citX; holo-ACP synthase [EC:2.7.7.61]
       K05966  citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
       K13927  citXG; holo-ACP synthase / triphosphoribosyl-dephospho-CoA synthase [EC:2.7.7.61 2.4.2.52]
       K09477  citT; citrate:succinate antiporter
       K07780  appY; AraC family transcriptional regulator, transcriptional regulator required for anaerobic and stationary phase induction of genes
       K11637  citS; two-component system, CitB family, sensor histidine kinase CitS [EC:2.7.13.3]
       K11638  K11638, citT; two-component system, CitB family, response regulator CitT
       K11639  citM; Mg2+/citrate complex secondary transporter
       K07701  dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
       K07703  dcuR; two-component system, CitB family, response regulator DcuR
       K07792  dcuB; anaerobic C4-dicarboxylate transporter DcuB
       K11691  K11691, dctS; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]
       K11692  K11692, dctR; two-component system, CitB family, response regulator DctR
       K11614  yufL, malK; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]
       K11615  malR; two-component system, CitB family, response regulator MalR
       K00027  E1.1.1.38, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
       K11616  maeN; malate:Na+ symporter
       K07704  lytS; two-component system, LytT family, sensor histidine kinase LytS [EC:2.7.13.3]
       K07705  lytT, lytR; two-component system, LytT family, response regulator LytT
       K05338  lrgA; holin-like protein
       K05339  lrgB; holin-like protein LrgB
       K08082  algZ; two-component system, LytT family, sensor histidine kinase AlgZ [EC:2.7.13.3]
       K08083  algR; two-component system, LytT family, response regulator AlgR
       K00066  algD; GDP-mannose 6-dehydrogenase [EC:1.1.1.132]
       K11640  natK; two-component system, LytT family, sensor histidine kinase NatK [EC:2.7.13.3]
       K11641  natR; two-component system, LytT family, response regulator NatR
       K09697  natA; sodium transport system ATP-binding protein
       K09696  natB; sodium transport system permease protein
       K07813  agrB; accessory gene regulator B
       K07800  agrD; AgrD protein
       K07706  agrC; two-component system, AgrA family, sensor histidine kinase AgrC [EC:2.7.13.-]
       K07707  agrA; two-component system, AgrA family, response regulator AgrA
       K12292  ABCC-BAC.COMA, comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]
       K12293  comB; competence factor transport accessory protein ComB
       K12415  K12415, comC; competence-stimulating peptide
       K12294  comD; two-component system, AgrA family, sensor histidine kinase ComD [EC:2.7.13.-]
       K12295  comE; two-component system, AgrA family, response regulator ComE
       K12296  comX1_2; competence protein ComX
       K07673  narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
       K07684  narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
       K07674  narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
       K07685  narP; two-component system, NarL family, nitrate/nitrite response regulator NarP
       K00370  narG; nitrate reductase alpha subunit [EC:1.7.99.4]
       K00371  narH; nitrate reductase beta subunit [EC:1.7.99.4]
       K00373  narJ; nitrate reductase delta subunit
       K00374  narI; nitrate reductase gamma subunit [EC:1.7.99.4]
       K08348  fdnG; formate dehydrogenase-N, alpha subunit [EC:1.1.5.6]
       K08349  fdnH; formate dehydrogenase-N, beta subunit
       K08350  fdnI; formate dehydrogenase-N, gamma subunit
       K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.5.4]
       K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.5.4]
       K00246  frdC; fumarate reductase subunit C
       K00247  frdD; fumarate reductase subunit D
       K07783  uhpC; MFS transporter, OPA family, sugar phosphate sensor protein UhpC
       K07675  uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
       K07686  uhpA; two-component system, NarL family, uhpT operon response regulator UhpA
       K07784  uhpT; MFS transporter, OPA family, hexose phosphate transport protein UhpT
       K06080  rcsF; RcsF protein
       K07677  rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
       K07676  rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
       K07781  rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor
       K07687  rcsB; two-component system, NarL family, captular synthesis response regulator RcsB
       K07678  barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
       K07689  uvrY; two-component system, NarL family, invasion response regulator UvrY
       K07782  sdiA; LuxR family transcriptional regulator
       K03563  csrA; carbon storage regulator
       K02253  comX; competence protein ComX
       K07680  comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
       K07691  comA; two-component system, NarL family, competent response regulator ComA
       K02252  comS; competence protein ComS
       K07679  evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
       K07690  evgA, bvgA; two-component system, NarL family, response regulator EvgA
       K07797  emrK; multidrug resistance protein K
       K07786  emrY; MFS transporter, multidrug resistance protein Y
       K07688  fimZ; two-component system, NarL family, response regulator, fimbrial Z protein, FimZ
       K01467  ampC; beta-lactamase class C [EC:3.5.2.6]
       K07777  degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
       K07692  degU; two-component system, NarL family, response regulator DegU
       K07778  desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
       K07693  desR; two-component system, NarL family, response regulator DesR
       K10255  FAD6, desA; omega-6 fatty acid desaturase (delta-12 desaturase) [EC:1.14.19.-]
       K07681  vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]
       K07694  vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR
       K11617  liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]
       K11618  liaR; two-component system, NarL family, response regulator LiaR
       K11619  liaI; lia operon protein LiaI
       K11620  liaH; lia operon protein LiaH
       K11621  liaG; lia operon protein LiaG
       K11622  liaF; lia operon protein LiaF
       K07682  devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]
       K07695  devR; two-component system, NarL family, response regulator DevR
       K07683  nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
       K07696  nreC; two-component system, NarL family, response regulator NreC
       K10851  nreA; nitrogen regulatory protein A
       K10850  narT; MFS transporter, NNP family, putative nitrate transporter
       K11623  ydfH; two-component system, NarL family, sensor histidine kinase YdfH [EC:2.7.13.3]
       K11624  ydfI; two-component system, NarL family, response regulator YdfI
       K11625  K11625; membrane protein YdfJ
       K00990  glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]
       K04751  glnB; nitrogen regulatory protein P-II 1
       K07708  glnL, ntrB; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
       K07712  glnG, ntrC; two-component system, NtrC family, nitrogen regulation response regulator GlnG
       K01915  glnA, GLUL; glutamine synthetase [EC:6.3.1.2]
       K13598  ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
       K13599  ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
       K02584  nifA; Nif-specific regulatory protein
       K07709  zraS, hydH; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
       K07713  zraR, hydG; two-component system, NtrC family, response regulator HydG
       K07803  zraP; zinc resistance-associated protein
       K07710  atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
       K07714  atoC; two-component system, NtrC family, response regulator AtoC
       K01034  atoD; acetate CoA/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]
       K01035  atoA; acetate CoA/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]
       K02106  atoE; short-chain fatty acids transporter
       K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
       K08478  pgtC; phosphoglycerate transport regulatory protein PgtC
       K08475  pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]
       K08476  pgtA; two-component system, NtrC family, phosphoglycerate transport system response regulator PgtA
       K11382  pgtP; MFS transporter, OPA family, phosphoglycerate transporter protein
       K10125  dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
       K10126  dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
       K11103  dctA; aerobic C4-dicarboxylate transport protein
       K02668  pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
       K02667  pilR; two-component system, NtrC family, response regulator PilR
       K03092  SIG54, rpoN; RNA polymerase sigma-54 factor
       K02650  pilA; type IV pilus assembly protein PilA
       K11383  kinB1, kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
       K11384  algB; two-component system, NtrC family, response regulator AlgB
       K07711  glrK, qseE; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
       K07715  glrR, qseF; two-component system, NtrC family, response regulator GlrR
       K15841  glmY; small regulatory RNA GlmY
       K14988  salK; two-component system, NarL family, secretion system sensor histidine kinase SalK
       K14989  salR; two-component system, NarL family, secretion system response regulator SalR
       K00575  cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
       K13924  cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
       K03406  mcp; methyl-accepting chemotaxis protein
       K05874  tsr; methyl-accepting chemotaxis protein I, serine sensor receptor
       K05875  tar; methyl-accepting chemotaxis protein II, aspartate sensor receptor
       K05876  trg; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor
       K05877  tap; methyl-accepting chemotaxis protein IV, peptide sensor receptor
       K03776  aer; aerotaxis receptor
       K03408  cheW; purine-binding chemotaxis protein CheW
       K03407  cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
       K03413  cheY; two-component system, chemotaxis family, response regulator CheY
       K03412  cheB; two-component system, chemotaxis family, response regulator CheB [EC:3.1.1.61]
       K03415  cheV; two-component system, chemotaxis family, response regulator CheV
       K02661  pilK; type IV pilus assembly protein PilK
       K02660  pilJ; twitching motility protein PilJ
       K02659  pilI; twitching motility protein PilI
       K06596  chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
       K02487  pilL; type IV pili sensor histidine kinase and response regulator
       K02657  pilG; twitching motility two-component system response regulator PilG
       K02658  pilH; twitching motility two-component system response regulator PilH
       K11525  pixJ; methyl-accepting chemotaxis protein PixJ
       K11524  pixI; positive phototaxis protein PixI
       K11526  pixL; two-component system, chemotaxis family, sensor histidine kinase and response regulator PixL
       K11522  pixG; two-component system, chemotaxis family, response regulator PixG
       K11523  pixH; two-component system, chemotaxis family, response regulator PixH
       K06597  chpB; chemosensory pili system protein ChpB (putative protein-glutamate methylesterase)
       K06598  chpC; chemosensory pili system protein ChpC
       K13486  wspC; chemotaxis protein methyltransferase WspC
       K13487  wspA; methyl-accepting chemotaxis protein WspA
       K13488  wspB; chemotaxis-related protein WspB
       K13489  wspD; chemotaxis-related protein WspD
       K13490  wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE
       K13491  wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61]
       K11444  wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65]
       K11354  cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
       K11355  rcp1; two-component system, chemotaxis family, response regulator Rcp1
       K07716  pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
       K02489  pleC1; two-component system, cell cycle sensor kinase and response regulator [EC:2.7.13.3]
       K02488  pleD; two-component system, cell cycle response regulator
       K11357  divJ; two-component system, cell cycle sensor histidine kinase DivJ [EC:2.7.13.3]
       K11443  divK; two-component system, cell cycle response regulator DivK
       K13587  cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
       K13588  chpT; histidine phosphotransferase ChpT
       K13584  ctrA; two-component system, cell cycle response regulator CtrA
       K13589  cpdR; two-component system, cell cycle response regulator CpdR
       K10910  luxP; autoinducer 2-binding periplasmic protein LuxP
       K10909  luxQ; two-component system, autoinducer 2 sensor kinase/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]
       K10916  cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]
       K15850  luxN; two-component system, autoinducer 1 sensor kinase/phosphatase LuxN [EC:2.7.13.3 3.1.3.-]
       K10911  luxU; two-component system, phosphorelay protein LuxU
       K10912  luxO; two-component system, repressor protein LuxO
       K15851  qrr; quorum regulatory RNA Qrr
       K15852  luxR; LuxR family transcriptional regulator, transcriptional activator of the bioluminescence operon
       K03400  luxC; long-chain-fatty-acyl-CoA reductase [EC:1.2.1.50]
       K15853  luxD; acyl transferase [EC:2.3.1.-]
       K00494  luxA; alkanal monooxygenase alpha chain [EC:1.14.14.3]
       K15854  luxB; alkanal monooxygenase beta chain [EC:1.14.14.3]
       K06046  luxE; long-chain-fatty-acid---luciferin-component ligase [EC:6.2.1.19]
       K11711  dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
       K11712  dctR; two-component system, LuxR family, response regulator DctR
       K11688  dctP; C4-dicarboxylate-binding protein DctP
       K11689  dctQ; C4-dicarboxylate transporter, DctQ subunit
       K11690  dctM; C4-dicarboxylate transporter, DctM subunit
       K13040  ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
       K13041  ttrR; two-component system, LuxR family, response regulator TtrR
       K08357  ttrA; tetrathionate reductase subunit A
       K08358  ttrB; tetrathionate reductase subunit B
       K08359  ttrC; tetrathionate reductase subunit C
       K14986  fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
       K14987  fixJ; two-component system, LuxR family, response regulator FixJ
       K15861  fixK; CRP/FNR family transcriptional regulator, nitrogen fixation regulation protein
       K14978  ssrA; two-component system, LuxR family, secretion system sensor histidine kinase SsrA
       K14979  ssrB; two-component system, LuxR family, secretion system response regulator SsrB
       K10941  flrA; sigma-54 specific transcriptional regulator, flagellar regulatory protein A
       K10942  flrB, fleS; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
       K10943  flrC, fleR; two-component system, response regulator FlrC
       K17060  aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
       K17061  aauR; two-component system, response regulator AauR
       K10004  gltL, aatP; glutamate/aspartate transport system ATP-binding protein [EC:3.6.3.-]
       K10002  gltK, aatM; glutamate/aspartate transport system permease protein
       K10003  gltJ, aatQ; glutamate/aspartate transport system permease protein
       K10001  gltI, aatJ; glutamate/aspartate transport system substrate-binding protein
       K05597  aspQ, ansB, ansA; glutamin-(asparagin-)ase [EC:3.5.1.38]
       K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
       K11232  YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
       K11233  SSK1; osomolarity two-component system, response regulator SSK1
       K11230  SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
       K15859  SKN7; osomolarity two-component system, response regulator SKN7
       K10715  rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
       K13815  rpfG; two-component system, response regulator RpfG
       K10914  crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
       K13816  rpfF; DSF synthase
       K07717  ycbA, glnK; two-component system, sensor histidine kinase YcbA [EC:2.7.13.3]
       K07719  ycbB, glnL; two-component system, response regulator YcbB
       K11626  glnT; putative sodium/glutamine symporter
       K07718  yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
       K07720  yesN; two-component system, response regulator YesN
       K11356  cikA; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
       K15011  regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
       K15012  regA, regR, actR; two-component system, response regulator RegA
       K08930  pucA; light-harvesting protein B-800-850 alpha chain
       K08939  pucB; light-harvesting protein B-800-850 beta chain
       K13994  pufX; photosynthetic reaction center PufX protein
       K08929  pufM; photosynthetic reaction center M subunit
       K08928  pufL; photosynthetic reaction center L subunit
       K08926  pufA; light-harvesting complex 1 alpha chain
       K08927  pufB; light-harvesting complex 1 beta chain
       K13991  puhA; photosynthetic reaction center H subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00410  fbcH; ubiquinol-cytochrome c reductase cytochrome b/c1 subunit
       K08738  CYC; cytochrome c
       K00404  ccoN; cytochrome c oxidase cbb3-type subunit I [EC:1.9.3.1]
       K00405  ccoO; cytochrome c oxidase cbb3-type subunit II
       K15862  ccoNO; cytochrome c oxidase cbb3-type subunit I/II [EC:1.9.3.1]
       K00407  ccoQ; cytochrome c oxidase cbb3-type subunit IV
       K00406  ccoP; cytochrome c oxidase cbb3-type subunit III
       K00425  cydA; cytochrome d ubiquinol oxidase subunit I [EC:1.10.3.-]
       K00426  cydB; cytochrome d ubiquinol oxidase subunit II [EC:1.10.3.-]
     02022 Two-component system [BR:ko02022]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway -fly [PATH:ko04391]
     04370 VEGF signaling pathway [PATH:ko04370]
     04630 Jak-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04022 cGMP - PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   Signaling molecules and interaction
 
 Cellular Processes
 
   Transport and catabolism
 
   Cell motility
 
   Cell growth and death
     04110 Cell cycle [PATH:ko04110]
     04111 Cell cycle - yeast [PATH:ko04111]
     04112 Cell cycle - Caulobacter [PATH:ko04112]
     04113 Meiosis - yeast [PATH:ko04113]
     04114 Oocyte meiosis [PATH:ko04114]
     04210 Apoptosis [PATH:ko04210]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04721  TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K04386  IL1R1; interleukin 1 receptor type I
       K04723  IL1RAP; interleukin 1 receptor accessory protein
       K02373  FADD; FAS-associated death domain protein
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K04724  CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K04396  CASP6; caspase 6 [EC:3.4.22.59]
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04726  BID; BH3 interacting domain death agonist
       K02161  BCL2; apoptosis regulator BCL-2
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02310  DFFA, DFF45; DNA fragmentation factor, 45 kD, alpha subunit
       K02311  DFFB, DFF40; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
       K04727  PDCD8, AIF; programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-]
       K01173  ENDOG; endonuclease G, mitochondrial
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K03173  TRAF2; TNF receptor-associated factor 2
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
       K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K02582  NGFB; nerve growth factor, beta
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K04736  IL3; interleukin 3
       K04737  IL3RA; interleukin 3 receptor alpha
       K04738  CSF2RB, IL3RB; cytokine receptor common subunit beta
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04739  PRKAR; cAMP-dependent protein kinase regulator
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K02158  BAD; BCL2-antagonist of cell death
       K02159  BAX; apoptosis regulator BAX
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
     04115 p53 signaling pathway [PATH:ko04115]
       K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
       K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:2.7.11.1]
       K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
       K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:2.7.11.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K10127  MDM4, MDMX; protein Mdm4
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04503  CCND1; cyclin D1
       K10151  CCND2; cyclin D2
       K10152  CCND3; cyclin D3
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06644  SFN; stratifin
       K10128  RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
       K05868  CCNB; cyclin B
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K10129  GTSE1, B99; G-2 and S-phase expressed protein 1
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K10130  LRDD, PIDD; leucine-rich repeats and death domain-containing protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K02159  BAX; apoptosis regulator BAX
       K10131  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; BCL2-binding component 3
       K13773  TP53AIP1; p53-regulated apoptosis-inducing protein 1
       K10133  TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
       K10134  EI24; etoposide-induced 2.4 mRNA
       K10135  SCOTIN; scotin
       K10136  PERP; TP53 apoptosis effector
       K10137  ZMAT3; zinc finger, matrin type 3
       K04506  SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19]
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K10138  IGFBP3; insulin-like growth factor-binding protein 3
       K05459  IGF1; insulin-like growth factor 1
       K03982  SERPINE1, PAI1; plasminogen activator inhibitor-1
       K04596  BAI1; brain-specific angiogenesis inhibitor 1
       K06509  KAI1, CD82, TSPAN27; CD82 antigen
       K16857  THBS1; thrombospondin 1
       K10139  SERPINB5; serpin B5
       K10140  DDB2; DNA damage-binding protein 2
       K10808  RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
       K10141  SESN; sestrin
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K07207  TSC2; tuberous sclerosis 2
       K10142  STEAP3, TSAP6; metalloreductase STEAP3 [EC:1.16.1.-]
       K10143  RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19]
       K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:6.3.2.19]
       K10145  CCNG1; cyclin G1
       K10146  CCNG2; cyclin G2
       K10147  PPM1D, WIP1; protein phosphatase 1D [EC:3.1.3.16]
       K10148  TP73; tumor protein p73
 
   Cell communication
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDHE, CDH1; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10; frizzled 9/10
       K02353  DVL; segment polarity protein dishevelled
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator BCL-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K07203  FRAP; FKBP12-rapamycin complex-associated protein
       K02158  BAD; BCL2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; proto-oncogene C-crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:6.3.2.19]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04358  FGF; fibroblast growth factor
       K04362  FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-binding protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04513  RHOA; Ras homolog gene family, member A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K10054  PML, TRIM19; probable transcription factor PML
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; runt-related transcription factor 1; translocated to, 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K05405  IL6; interleukin 6
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  EVI1; ecotropic virus integration site 1 protein
       K04496  CTBP; C-terminal binding protein
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K02159  BAX; apoptosis regulator BAX
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  TCEB1; transcription elongation factor B, polypeptide 1
       K03873  TCEB2; transcription elongation factor B, polypeptide 2
       K03868  RBX1, ROC1; RING-box protein 1
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06227  COS2; costal 2
       K06228  FU; fused [EC:2.7.11.1]
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K04662  BMP2_4; bone morphogenetic protein 2/4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  NR3C4, AR; androgen receptor
       K04079  htpG, HSP90A; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancers [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
     05204 Chemical carcinogenesis [PATH:ko05204]
     05203 Viral carcinogenesis [PATH:ko05203]
     05210 Colorectal cancer [PATH:ko05210]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02105  CTNNB1; catenin beta 1
       K02085  APC; adenomatosis polyposis coli protein
       K02620  TCF7; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; cyclin D1
       K07827  KRAS, KRAS2; GTPase KRas
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02158  BAD; BCL2-antagonist of cell death
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04513  RHOA; Ras homolog gene family, member A
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08733  APPL, DIP13A; DCC-interacting protein 13 alpha
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2_3; mothers against decapentaplegic homolog 2/3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K02159  BAX; apoptosis regulator BAX
       K02161  BCL2; apoptosis regulator BCL-2
       K08738  CYC; cytochrome c
       K04451  TP53, P53; tumor protein p53
     05212 Pancreatic cancer [PATH:ko05212]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05222 Small cell lung cancer [PATH:ko05222]
       K01522  FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K08525  NR2B2, RXRB; retinoid X receptor beta
       K08526  NR2B3, RXRG; retinoid X receptor gamma
       K04451  TP53, P53; tumor protein p53
       K02161  BCL2; apoptosis regulator BCL-2
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04377  MYC; Myc proto-oncogene protein
       K04453  MAX; Max protein
       K16063  PIAS2; E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-]
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K04503  CCND1; cyclin D1
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; cyclin E
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06237  COL4A; collagen, type IV, alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2; integrin alpha 2
       K06476  ITGA2B; integrin alpha 2B
       K06482  ITGA3; integrin alpha 3
       K06485  ITGA6; integrin alpha 6
       K06487  ITGAV; integrin alpha V
       K05719  ITGB1; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   Immune diseases
 
   Neurodegenerative diseases
     05010 Alzheimer's disease [PATH:ko05010]
       K06704  ADAM10; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
       K06059  ADAM17, TACE; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
       K04520  APP; amyloid beta A4 protein
       K04532  APPBP1; amyloid beta precursor protein binding protein 1
       K04529  APBB1, FE65; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
       K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
       K04521  BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
       K07747  BACE2; beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45]
       K06170  PEN2; presenilin enhancer 2
       K04505  PSEN1, PS1; presenilin 1 [EC:3.4.23.-]
       K04522  PSEN2, PS2; presenilin 2 [EC:3.4.23.-]
       K06171  NCSTN; nicastrin
       K06172  APH1; anterior pharynx defective 1
       K01408  IDE, ide; insulysin [EC:3.4.24.56]
       K01389  MME; neprilysin [EC:3.4.24.11]
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
       K02132  ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
       K02133  ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
       K02136  ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
       K02134  ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
       K02135  ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
       K02126  ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
       K02127  ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
       K02128  ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
       K02138  ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
       K02137  ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
       K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
       K02125  ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
       K08683  HSD17B10; 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]
       K01059  LPL; lipoprotein lipase [EC:3.1.1.34]
       K04524  APOE; apolipoprotein E
       K04550  LRP1, CD91; low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor)
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K02183  CALM; calmodulin
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K02158  BAD; BCL2-antagonist of cell death
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K04850  CACNA1C; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S; voltage-dependent calcium channel L type alpha-1S
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04963  RYR3; ryanodine receptor 3
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K05853  ATP2A; Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8]
       K09054  ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K11716  CDK5R1; cyclin-dependent kinase 5 activator 1
       K02090  CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
       K04380  MAPT, TAU; microtubule-associated protein tau
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K04528  SNCA; synuclein, alpha (non A4 component of amyloid precursor)
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04519  IL1B; interleukin 1 beta
     05012 Parkinson's disease [PATH:ko05012]
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04633  GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
       K04145  DRD2; dopamine receptor D2
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04144  DRD1; dopamine receptor D1
       K03178  UBE1, UBA1; ubiquitin-activating enzyme E1 [EC:6.3.2.19]
       K10698  UBE1L, UBA7; ubiquitin-activating enzyme E1-like [EC:6.3.2.19]
       K04551  UBB; ubiquitin B
       K04552  UBE2L3, UBCH7; ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19]
       K04553  UBE2L6, UBCH8; ubiquitin-conjugating enzyme E2 L6 [EC:6.3.2.19]
       K04554  UBE2J2, NCUBE2, UBC6; ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19]
       K10578  UBE2J1, NCUBE1, UBC6; ubiquitin-conjugating enzyme E2 J1 [EC:6.3.2.19]
       K04555  UBE2G2, UBC7; ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19]
       K10575  UBE2G1, UBC7; ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19]
       K04556  PARK2; parkin [EC:6.3.2.19]
       K04528  SNCA; synuclein, alpha (non A4 component of amyloid precursor)
       K04243  GPR37; G protein-coupled receptor 37 (endothelin receptor type B-like)
       K04557  SEPT5, PNUTL1, CDCREL1; septin 5
       K04558  SNCAIP; synuclein, alpha interacting protein (synphilin)
       K05611  UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
       K00501  TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
       K05036  SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine) member 3
       K08155  SLC18A1_2, VMAT; MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2
       K03878  ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3]
       K03879  ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3]
       K03880  ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3]
       K03881  ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3]
       K03882  ND4L; NADH-ubiquinone oxidoreductase chain 4L [EC:1.6.5.3]
       K03883  ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3]
       K03884  ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3]
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
       K02132  ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
       K02133  ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
       K02136  ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
       K02134  ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
       K02135  ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
       K02126  ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
       K02127  ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
       K02128  ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
       K02138  ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
       K02137  ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
       K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
       K02125  ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
       K08844  LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
       K05688  PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
       K05687  PARK7; protein DJ-1
       K08669  HTRA2, PRSS25; HtrA serine peptidase 2 [EC:3.4.21.108]
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
     05014 Amyotrophic lateral sclerosis (ALS) [PATH:ko05014]
       K04451  TP53, P53; tumor protein p53
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K04726  BID; BH3 interacting domain death agonist
       K02161  BCL2; apoptosis regulator BCL-2
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K02159  BAX; apoptosis regulator BAX
       K02158  BAD; BCL2-antagonist of cell death
       K02084  APAF1; apoptotic protease-activating factor
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K11518  TOM40; mitochondrial import receptor subunit TOM40
       K11519  DERL1; Derlin-1
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K05141  TNFRSF1B, TNFR2; tumor necrosis factor receptor superfamily member 1B
       K02308  DAXX; death-associated protein 6
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K13240  NOS1; nitric-oxide synthase, brain [EC:1.14.13.39]
       K04569  CCS; copper chaperone for superoxide dismutase
       K03781  katE, CAT, catB, srpA; catalase [EC:1.11.1.6]
       K07607  PRPH; peripherin
       K04572  NEFL, NF-L; neurofilament light polypeptide
       K04573  NEF3, NF-M; neurofilament medium polypeptide (neurofilament 3)
       K04574  NEFH, NF-H; neurofilament heavy polypeptide
       K04575  ALS2; amyotrophic lateral sclerosis 2 protein
       K07887  RAB5A; Ras-related protein Rab-5A
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K05613  SLC1A2, EAAT2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
     05016 Huntington's disease [PATH:ko05016]
       K04644  CLTA, LCA; clathrin light chain A
       K04645  CLTB, LCB; clathrin light chain B
       K04646  CLTC; clathrin heavy chain
       K04559  HIP1; huntingtin interacting protein 1
       K11824  AP2A; AP-2 complex subunit alpha
       K11825  AP2B1; AP-2 complex subunit beta-1
       K11826  AP2M1; AP-2 complex subunit mu-1
       K11827  AP2S1; AP-2 complex subunit sigma-1
       K04533  HD; huntingtin
       K04638  ESRRBL1, HIPPI; estrogen-related receptor beta like 1
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04604  GRM5; metabotropic glutamate receptor 5
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K11828  DLG4, PSD95; discs large protein 4
       K05625  TGM2; transglutaminase 2 [EC:2.3.2.13]
       K09222  REST; RE1-silencing transcription factor
       K11644  SIN3A; paired amphipathic helix protein Sin3a
       K11829  RCOR1, COREST; REST corepressor 1
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K03010  RPB2, POLR2B; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
       K03011  RPB3, POLR2C; DNA-directed RNA polymerase II subunit RPB3
       K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
       K03013  RPB5, POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1
       K03014  RPB6, POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2
       K03015  RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
       K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
       K03017  RPB9, POLR2I; DNA-directed RNA polymerase II subunit RPB9
       K03007  RPB10, POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
       K03008  RPB11, POLR2J; DNA-directed RNA polymerase II subunit RPB11
       K03009  RPB12, POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
       K04355  BDNF; brain-derived neurotrophic factor
       K04648  DCTN1; dynactin 1
       K10424  DCTN2; dynactin 2
       K10426  DCTN4; dynactin 4
       K04647  HAP1; huntingtin-associated protein 1
       K10408  DNAH; dynein heavy chain, axonemal
       K10410  DNALI; dynein light intermediate chain, axonemal
       K10409  DNAI1; dynein intermediate chain 1, axonemal
       K11143  DNAI2; dynein intermediate chain 2, axonemal
       K10411  DNAL1; dynein light chain 1, axonemal
       K10412  DNAL4; dynein light chain 4, axonemal
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K03129  TAF4; transcription initiation factor TFIID subunit 4
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K04684  SP1; transcription factor Sp1
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K07202  PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K11830  TFAM, MTTFA; transcription factor A, mitochondrial
       K11831  NRF1; nuclear respiratory factor 1
       K04565  SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
       K04564  SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
       K08769  UCP1, SLC25A7; solute carrier family 25 (mitochondrial uncoupling protein), member 7
       K04451  TP53, P53; tumor protein p53
       K02159  BAX; apoptosis regulator BAX
       K10132  BBC3, PUMA; BCL2-binding component 3
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
       K02132  ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha
       K02133  ATPeF1B, ATP5B, ATP2; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]
       K02136  ATPeF1G, ATP5C1, ATP3; F-type H+-transporting ATPase subunit gamma
       K02134  ATPeF1D, ATP5D, ATP16; F-type H+-transporting ATPase subunit delta
       K02135  ATPeF1E, ATP5E, ATP15; F-type H+-transporting ATPase subunit epsilon
       K02126  ATPeF0A, MTATP6, ATP6; F-type H+-transporting ATPase subunit a
       K02127  ATPeF0B, ATP5F1, ATP4; F-type H+-transporting ATPase subunit b
       K02128  ATPeF0C, ATP5G, ATP9; F-type H+-transporting ATPase subunit c
       K02138  ATPeF0D, ATP5H, ATP7; F-type H+-transporting ATPase subunit d
       K02137  ATPeF0O, ATP5O, ATP5; F-type H+-transporting ATPase subunit O
       K02131  ATPeF0F6, ATP5J; F-type H+-transporting ATPase subunit 6
       K02125  ATPeF08, MTATP8, ATP8; F-type H+-transporting ATPase subunit 8
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K05863  SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
     05020 Prion diseases [PATH:ko05020]
 
   Substance dependence
 
   Cardiovascular diseases
     05410 Hypertrophic cardiomyopathy (HCM) [PATH:ko05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ko05412]
     05414 Dilated cardiomyopathy (DCM) [PATH:ko05414]
     05416 Viral myocarditis [PATH:ko05416]
       K06788  CXADR, CAR; coxsackievirus and adenovirus receptor
       K04006  DAF, CD55; decay accelerating factor
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K06278  CAV1; caveolin 1
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K12563  SGCD; delta-sarcoglycan
       K12564  SGCG; gamma-sarcoglycan
       K12565  SGCA; alpha-sarcoglycan
       K12566  SGCB; beta-sarcoglycan
       K06265  DAG1; dystroglycan 1
       K10366  DMD; dystrophin
       K05692  ACTB_G1; actin beta/gamma 1
       K03260  EIF4G; translation initiation factor 4G
       K04503  CCND1; cyclin D1
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K17751  MYH6_7; myosin heavy chain 6/7
       K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K06752  MHC2; major histocompatibility complex, class II
       K10784  TRAV; T cell receptor alpha chain V region
       K10785  TRBV; T-cell receptor beta chain V region
       K06751  MHC1; major histocompatibility complex, class I
       K05412  CD80; CD80 antigen
       K05413  CD86; CD86 antigen
       K06470  CD28; CD28 antigen
       K07818  PRF1; perforin 1
       K05718  ITGAL; integrin alpha L
       K06464  ITGB2; integrin beta 2
       K06490  ICAM1; intercellular adhesion molecule 1
       K06856  IGH; immunoglobulin heavy chain
 
   Endocrine and metabolic diseases
     04940 Type I diabetes mellitus [PATH:ko04940]
     04930 Type II diabetes mellitus [PATH:ko04930]
     04950 Maturity onset diabetes of the young [PATH:ko04950]
     04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:ko04932]
       K05405  IL6; interleukin 6
       K05055  IL6R; interleukin 6 receptor
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04526  INS; insulin
       K04527  INSR; insulin receptor [EC:2.7.10.1]
       K16172  IRS1; insulin receptor substrate 1
       K07187  IRS2; insulin receptor substrate 2
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K08536  NR1H3, LXRA; liver X receptor alpha
       K08524  NR2B1, RXRA; retinoid X receptor alpha
       K07197  SREBP1, SREBF1; sterol regulatory element-binding transcription factor 1
       K09113  MLX; MAX-like protein X
       K12406  PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
       K05424  LEP; leptin
       K05062  LEPR; leptin receptor
       K07296  ACDC; adiponectin
       K07297  ADIPOR; adiponectin receptor
       K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
       K07199  PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
       K07200  PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K05632  AIP4, ITCH; atrophin-1 interacting protein 4 [EC:6.3.2.19]
       K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
       K03173  TRAF2; TNF receptor-associated factor 2
       K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
       K04448  JUN; transcription factor AP-1
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K09027  XBP1; X box-binding protein 1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K07415  CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K10030  IL8, CXCL8; interleukin 8
       K13375  TGFB1; transforming growth factor beta-1
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K04452  DDIT3, GADD153; DNA damage-inducible transcript 3
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K02159  BAX; apoptosis regulator BAX
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K08738  CYC; cytochrome c
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K03942  NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3]
       K03943  NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3]
       K03944  NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
       K03945  NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
       K03946  NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
       K03947  NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
       K03948  NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
       K03949  NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
       K03950  NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
       K03951  NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
       K03952  NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
       K03953  NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
       K03954  NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
       K03955  NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1
       K03956  NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
       K11352  NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
       K11353  NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
       K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
       K03958  NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
       K03959  NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
       K03960  NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
       K03961  NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
       K03962  NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
       K03963  NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
       K03964  NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
       K03965  NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
       K03966  NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
       K11351  NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
       K03934  NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3]
       K03935  NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3]
       K03936  NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3]
       K03937  NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
       K03938  NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
       K03939  NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
       K03940  NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3]
       K03941  NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3]
       K03967  NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
       K03968  NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
       K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
       K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
       K00236  SDHC, SDH3; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
       K00237  SDHD, SDH4; succinate dehydrogenase (ubiquinone) membrane anchor subunit
       K00411  UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]
       K00412  CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit
       K00413  CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit
       K00414  QCR1, UQCRC1; ubiquinol-cytochrome c reductase core subunit 1
       K00415  QCR2, UQCRC2; ubiquinol-cytochrome c reductase core subunit 2
       K00416  QCR6, UQCRH; ubiquinol-cytochrome c reductase subunit 6
       K00417  QCR7, UQCRB; ubiquinol-cytochrome c reductase subunit 7
       K00418  QCR8, UQCRQ; ubiquinol-cytochrome c reductase subunit 8
       K00419  QCR9, UCRC; ubiquinol-cytochrome c reductase subunit 9
       K00420  QCR10, UQCR; ubiquinol-cytochrome c reductase subunit 10
       K02262  COX3; cytochrome c oxidase subunit 3
       K02256  COX1; cytochrome c oxidase subunit 1 [EC:1.9.3.1]
       K02261  COX2; cytochrome c oxidase subunit 2
       K02263  COX4; cytochrome c oxidase subunit 4
       K02264  COX5A; cytochrome c oxidase subunit 5a
       K02265  COX5B; cytochrome c oxidase subunit 5b
       K02266  COX6A; cytochrome c oxidase subunit 6a
       K02267  COX6B; cytochrome c oxidase subunit 6b
       K02268  COX6C; cytochrome c oxidase subunit 6c
       K02270  COX7A; cytochrome c oxidase subunit 7a
       K02271  COX7B; cytochrome c oxidase subunit 7b
       K02272  COX7C; cytochrome c oxidase subunit 7c
       K02273  COX8; cytochrome c oxidase subunit 8
 
   Infectious diseases
     05110 Vibrio cholerae infection [PATH:ko05110]
     05111 Vibrio cholerae pathogenic cycle [PATH:ko05111]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
     05131 Shigellosis [PATH:ko05131]
     05133 Pertussis [PATH:ko05133]
     05134 Legionellosis [PATH:ko05134]
       K15473  sdeA, laiA; effector protein SdeA
       K11022  rtxA1, rtxA; structural toxin protein (hemagglutinin/hemolysin) RtxA
       K15474  enhC; enhanced entry protein EnhC
       K15475  lpnE; enhanced entry protein LpnE
       K03197  virB2, lvhB2; type IV secretion system protein VirB2
       K04077  groEL, HSPD1; chaperonin GroEL
       K03990  C3; complement component 3
       K04011  CR1, CD35; complement component (3b/4b) receptor 1
       K06461  ITGAM; integrin alpha M
       K06464  ITGB2; integrin beta 2
       K15476  vipA; VPS inhibitor protein A
       K15477  vipD; VPS inhibitor protein D
       K15478  vipE; VPS inhibitor protein E
       K15479  ralF; guanine nucleotide exchange protein RalF
       K07937  ARF1; ADP-ribosylation factor 1
       K15480  sidM, drrA; effector protein DrrA/SidM
       K07874  RAB1A; Ras-related protein Rab-1A
       K07875  RAB1B; Ras-related protein Rab-1B
       K15481  lidA; effector protein LidA
       K15482  sidC; effector protein SidC
       K15483  sdcA; effector protein SdcA
       K08517  SEC22; vesicle transport protein SEC22
       K07953  SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
       K13525  VCP, CDC48; transitional endoplasmic reticulum ATPase
       K02084  APAF1; apoptotic protease-activating factor
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
       K15484  sidF; inhibitor of growth protein SidF
       K15464  BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       K15485  BCL2L13, BCL-RAMBO; Bcl-2-like protein 13
       K15486  legK1; serine/threonine-protein kinase LegK1 [EC:2.7.1.-]
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K15487  sdbA; effector protein SdbA
       K15488  lubX; E3 ubiquitin-protein ligase LubX [EC:6.3.2.19]
       K15490  lgt1_2_3; glucosyltransferase Lgt1/2/3
       K14416  HBS1; elongation factor 1 alpha-like protein
       K15491  sidI; effector protein SidI
       K03231  EEF1A; elongation factor 1-alpha
       K09414  HSF1; heat shock transcription factor 1
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K03233  EEF1G; elongation factor 1-gamma
       K03596  lepA; GTP-binding protein LepA
       K15492  K15492, lepB; effector protein B
       K02406  fliC; flagellin
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K05482  IL18, IL1F4; interleukin 18
       K04519  IL1B; interleukin 1 beta
       K10168  TLR5; toll-like receptor 5
       K10159  TLR2; toll-like receptor 2
       K04391  CD14; CD14 antigen
       K10160  TLR4; toll-like receptor 4
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K10030  IL8, CXCL8; interleukin 8
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04726  BID; BH3 interacting domain death agonist
       K02159  BAX; apoptosis regulator BAX
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02084  APAF1; apoptotic protease-activating factor
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02158  BAD; BCL2-antagonist of cell death
       K02161  BCL2; apoptosis regulator BCL-2
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K08060  CIITA; class II, major histocompatibility complex, transactivator
       K08061  RFX5; regulatory factor X 5
       K08062  RFXANK; regulatory factor X-associated ankyrin-containing protein
       K08063  RFXAP; regulatory factor X-associated protein
       K08064  NFYA; nuclear transcription factor Y, alpha
       K08065  NFYB; nuclear transcription Y subunit beta
       K08066  NFYC; nuclear transcription factor Y, gamma
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K06752  MHC2; major histocompatibility complex, class II
       K06505  CD74, DHLAG; CD74 antigen
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K05443  IL10, CSIF; interleukin 10
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K01368  CTSS; cathepsin S [EC:3.4.22.27]
       K10059  CLEC4E; C-type lectin domain family 4 member E
       K07983  FCER1G; Fc receptor, IgE, high affinity I, gamma polypeptide
       K10074  CLEC7A; C-type lectin domain family 7 member A
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
       K12794  CARD9; caspase recruitment domain-containing protein 9
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K07368  BCL10; B-cell CLL/lymphoma 10
       K14952  namH; UDP-MurNAc hydroxylase
       K10165  NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K14953  lpqH; ipoprotein LpqH
       K14954  lprG; lipoprotein LprG
       K14955  lprA; lipoprotein LprA
       K02040  pstS; phosphate transport system substrate-binding protein
       K04043  dnaK; molecular chaperone DnaK
       K04077  groEL, HSPD1; chaperonin GroEL
       K14956  esxA, esat6; 6 kDa early secretory antigenic target
       K05399  LBP; lipopolysaccharide-binding protein
       K10159  TLR2; toll-like receptor 2
       K05398  TLR1; toll-like receptor 1
       K10169  TLR6; toll-like receptor 6
       K10160  TLR4; toll-like receptor 4
       K04391  CD14; CD14 antigen
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05482  IL18, IL1F4; interleukin 18
       K05426  IL23A; interleukin 23, alpha subunit p19
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K10048  CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
       K10049  CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
       K10161  TLR9; toll-like receptor 9
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K06563  CD209; CD209 antigen
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K04513  RHOA; Ras homolog gene family, member A
       K14957  LSP1; lymphocyte-specific protein 1
       K08862  PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
       K14958  KSR1; kinase suppressor of Ras 1
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K07438  CYP27B; 25-hydroxyvitamin D3 1alpha-hydroxylase [EC:1.14.13.13]
       K08539  NR1I1, VDR; vitamin D3 receptor
       K13916  CAMP, LL37; cathelicidin antimicrobial peptide
       K03990  C3; complement component 3
       K04011  CR1, CD35; complement component (3b/4b) receptor 1
       K06462  ITGAX; integrin alpha X
       K06464  ITGB2; integrin beta 2
       K06461  ITGAM; integrin alpha M
       K06560  MRC; mannose receptor, C type
       K04718  SPHK; sphingosine kinase [EC:2.7.1.91]
       K02183  CALM; calmodulin
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K12478  EEA1; early endosome antigen 1
       K07897  RAB7A; Ras-related protein Rab-7A
       K01379  CTSD; cathepsin D [EC:3.4.23.5]
       K02154  ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02155  ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
       K03661  ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
       K06528  LAMP1_2, CD107; lysosomal-associated membrane protein 1/2
       K01078  E3.1.3.2; acid phosphatase [EC:3.1.3.2]
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K13882  CORO1A; coronin-1A
       K14949  pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
       K06856  IGH; immunoglobulin heavy chain
       K06498  FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
       K06472  FCGR2A, CD32; low affinity immunoglobulin gamma Fc region receptor II-a
       K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
       K16824  FCGR2C, CD32; low affinity immunoglobulin gamma Fc region receptor II-c
       K06463  FCGR3, CD16; low affinity immunoglobulin gamma Fc region receptor III
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
     05166 HTLV-I infection [PATH:ko05166]
     05162 Measles [PATH:ko05162]
     05164 Influenza A [PATH:ko05164]
       K01312  PRSS; trypsin [EC:3.4.21.4]
       K09633  TMPRSS2; transmembrane protease, serine 2
       K09635  TMPRSS4; transmembrane protease, serine 4
       K14216  OAS; 2'-5'-oligoadenylate synthetase
       K01165  RNASEL; ribonuclease L
       K09507  DNAJB1; DnaJ homolog subfamily B member 1
       K09523  DNAJC3; DnaJ homolog subfamily C member 3
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K12653  NLRX1; NLR family member X1
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K10652  TRIM25, EFP; tripartite motif-containing protein 25 [EC:6.3.2.19]
       K05401  TLR3; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K10160  TLR4; toll-like receptor 4
       K05404  TLR7; toll-like receptor 7
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K09447  IRF7; interferon regulatory factor 7
       K04383  IL1A; interleukin 1 alpha
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K10030  IL8, CXCL8; interleukin 8
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12499  CCL5; C-C motif chemokine 5
       K12671  CXCL10, IP10; C-X-C motif chemokine 10
       K06490  ICAM1; intercellular adhesion molecule 1
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K14754  MX1; interferon-induced GTP-binding protein Mx1
       K12968  ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
       K10054  PML, TRIM19; probable transcription factor PML
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K08060  CIITA; class II, major histocompatibility complex, transactivator
       K06752  MHC2; major histocompatibility complex, class II
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K05482  IL18, IL1F4; interleukin 18
       K12967  IL33; interleukin 33
       K04721  TNFSF10, TRAIL; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10, TRAILR; tumor necrosis factor receptor superfamily member 10
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K15042  KPNA1; importin subunit alpha-1
       K15043  KPNA2; importin subunit alpha-2
       K12812  UAP56, BAT1, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
       K14290  XPO1, CRM1; exportin-1
       K15044  AGFG1; Arf-GAP domain and FG repeats-containing protein 1
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K15045  RSAD2; radical S-adenosyl methionine domain-containing protein 2
       K00787  FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
       K05692  ACTB_G1; actin beta/gamma 1
       K15046  NS1BP; influenza virus NS1A-binding protein
       K14404  CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
       K14396  PABPN1, PABP2; polyadenylate-binding protein 2
       K14284  NXF1_2, TAP; nuclear RNA export factor 1/2
       K14285  NXT1_2, P15; NTF2-related export protein 1/2
       K14298  RAE1; mRNA export factor
       K15047  HNRNPUL1, E1BAP5; heterogeneous nuclear ribonucleoprotein U-like protein 1
       K14297  NUP98, ADAR2; nuclear pore complex protein Nup98-Nup96
       K01349  FURIN, PCSK3; furin [EC:3.4.21.75]
       K09643  TMPRSS13, TMPRSS11; transmembrane protease, serine 13
       K01315  PLG; plasminogen [EC:3.4.21.7]
     05161 Hepatitis B [PATH:ko05161]
       K06255  HSPG2; heparan sulfate proteoglycan 2 (perlecan)
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04377  MYC; Myc proto-oncogene protein
       K12496  EGR2; early growth response protein 2
       K12497  EGR3; early growth response protein 3
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04400  CASP10; caspase 10 [EC:3.4.22.63]
       K10610  DDB1; DNA damage-binding protein 1
       K10140  DDB2; DNA damage-binding protein 2
       K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
       K16197  YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K02161  BCL2; apoptosis regulator BCL-2
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K02158  BAD; BCL2-antagonist of cell death
       K04451  TP53, P53; tumor protein p53
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K02084  APAF1; apoptotic protease-activating factor
       K16344  HBXIP; hepatitis B virus X-interacting protein
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K02159  BAX; apoptosis regulator BAX
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04364  GRB2; growth factor receptor-binding protein 2
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04448  JUN; transcription factor AP-1
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04450  ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
       K10030  IL8, CXCL8; interleukin 8
       K04802  PCNA; proliferating cell nuclear antigen
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04692  STAT3; signal transducer and activator of transcription 3
       K11222  STAT4; signal transducer and activator of transcription 4
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K11225  STAT6; signal transducer and activator of transcription 6
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02677  CPKC; classical protein kinase C [EC:2.7.11.13]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K04374  ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K09049  ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
       K04379  FOS; proto-oncogene protein c-fos
       K04375  ELK1; ETS domain-containing protein Elk-1
       K11594  DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
       K05414  IFNA; interferon alpha
       K05130  IFNAR1; interferon receptor 1
       K05401  TLR3; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K10160  TLR4; toll-like receptor 4
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05415  IFNB; interferon beta
       K10159  TLR2; toll-like receptor 2
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K05405  IL6; interleukin 6
       K04503  CCND1; cyclin D1
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K06618  RB1; retinoblastoma-associated protein
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06626  CCNE; cyclin E
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06627  CCNA; cyclin A
     05160 Hepatitis C [PATH:ko05160]
     05168 Herpes simplex infection [PATH:ko05168]
       K05468  LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
       K05477  TNFSF14, LIGHT; tumor necrosis factor ligand superfamily member 14
       K05152  TNFRSF14, HVEM; tumor necrosis factor receptor superfamily member 14
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2
       K03174  TRAF3; TNF receptor-associated factor 3
       K09849  TRAF5; TNF receptor-associated factor 5
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K06081  PVRL1; poliovirus receptor-related protein 1
       K06531  PVRL2; poliovirus receptor-related protein 2
       K15411  PILRA; paired immunoglobulin-like type 2 receptor alpha
       K07293  PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K10159  TLR2; toll-like receptor 2
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K03175  TRAF6; TNF receptor-associated factor 6
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K10161  TLR9; toll-like receptor 9
       K05401  TLR3; toll-like receptor 3
       K05842  TRIF; toll-like receptor adapter molecule 1
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12499  CCL5; C-C motif chemokine 5
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05433  IL15; interleukin 15
       K05414  IFNA; interferon alpha
       K14217  IFIT1; interferon-induced protein with tetratricopeptide repeats 1
       K11838  USP7, UBP15; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.1.2.15]
       K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
       K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
       K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
       K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
       K03237  EIF2S1; translation initiation factor 2 subunit 1
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K14216  OAS; 2'-5'-oligoadenylate synthetase
       K01165  RNASEL; ribonuclease L
       K03990  C3; complement component 3
       K03994  C5; complement component 5
       K15412  CFP; complement factor properdin
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K02207  UBE2R, UBC3, CDC34; ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19]
       K03347  CUL1, CDC53; cullin 1
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K15410  EEF1D; elongation factor 1-delta
       K14840  NOP53, GLTSCR2; nucleolar protein 53
       K11674  MCRS1, INO80Q; microspherule protein 1
       K03006  RPB1, POLR2A; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
       K15409  SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
       K12890  SFRS1_9; splicing factor, arginine/serine-rich 1/9
       K12891  SFRS2; splicing factor, arginine/serine-rich 2
       K12892  SFRS3; splicing factor, arginine/serine-rich 3
       K12893  SFRS4_5_6; splicing factor, arginine/serine-rich 4/5/6
       K12896  SFRS7; splicing factor, arginine/serine-rich 7
       K10054  PML, TRIM19; probable transcription factor PML
       K15413  SP100; nuclear autoantigen Sp-100
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04451  TP53, P53; tumor protein p53
       K02308  DAXX; death-associated protein 6
       K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
       K03115  CSNK2B; casein kinase II subunit beta
       K14966  HCFC; host cell factor
       K03120  TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
       K03133  TAF9B, TAF9; transcription initiation factor TFIID subunit 9B
       K03131  TAF6; transcription initiation factor TFIID subunit 6
       K03130  TAF5; transcription initiation factor TFIID subunit 5
       K03129  TAF4; transcription initiation factor TFIID subunit 4
       K14650  TAF3; transcription initiation factor TFIID subunit 3
       K03127  TAF13; transcription initiation factor TFIID subunit 13
       K03134  TAF10; transcription initiation factor TFIID subunit 10
       K15129  MED8; mediator of RNA polymerase II transcription subunit 8
       K03121  TFII-I, GTF2I; transcription initiation factor TFII-I
       K11299  HMGN1; high-mobility group nucleosome-binding domain-containing protein 1
       K12881  THOC4, ALY; THO complex subunit 4
       K14284  NXF1_2, TAP; nuclear RNA export factor 1/2
       K15414  C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
       K12886  HNRNPK; heterogeneous nuclear ribonucleoprotein K
       K06752  MHC2; major histocompatibility complex, class II
       K06505  CD74, DHLAG; CD74 antigen
       K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
       K05654  ABCB3, TAP2; ATP-binding cassette, subfamily B (MDR/TAP), member 3
       K06751  MHC1; major histocompatibility complex, class I
       K05415  IFNB; interferon beta
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K04696  SOCS3, CIS3; suppressor of cytokine signaling 3
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K04389  TNFSF6, FASL; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS; tumor necrosis factor receptor superfamily member 6
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08738  CYC; cytochrome c
       K02296  ARNTL, BMAL1, CYC; aryl hydrocarbon receptor nuclear translocator-like protein 1
       K02223  CLOCK, KAT13D; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
       K02633  PER; period circadian protein
     05169 Epstein-Barr virus infection [PATH:ko05169]
     05146 Amoebiasis [PATH:ko05146]
     05144 Malaria [PATH:ko05144]
     05145 Toxoplasmosis [PATH:ko05145]
       K04687  IFNG; interferon gamma
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K08060  CIITA; class II, major histocompatibility complex, transactivator
       K06752  MHC2; major histocompatibility complex, class II
       K14139  IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
       K14140  IGTP; interferon gamma induced GTPase
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K04694  SOCS1, JAB; suppressor of cytokine signaling 1
       K14141  PFNL; profilin-like protein
       K14142  TLR11; toll-like receptor 11
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K04371  MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04440  JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K03156  TNFA; tumor necrosis factor superfamily, member 2
       K02161  BCL2; apoptosis regulator BCL-2
       K04570  BCL2L1, bcl-xL; BCL2-like 1 (apoptosis regulator Bcl-X)
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K05400  LY96, MD-2; lymphocyte antigen 96
       K10160  TLR4; toll-like receptor 4
       K03283  HSPA1_8; heat shock 70kDa protein 1/8
       K10159  TLR2; toll-like receptor 2
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K06485  ITGA6; integrin alpha 6
       K05719  ITGB1; integrin beta 1
       K14143  SAG; major surface antigen
       K14144  MIC3; microneme protein
       K13412  CPK; calcium-dependent protein kinase [EC:2.7.11.1]
       K13845  AMA-1; apical merozoite antigen 1
       K14145  RON2; rhoptry neck protein 2
       K14146  RON4; rhoptry neck protein 4
       K12473  LDLR; low-density lipoprotein receptor
       K14147  GRA7; dense granule protein 7
       K14148  ROP2; rhoptry protein 2
       K14149  GRA3; dense granule protein 3
       K14150  GRA5; dense granule protein 5
       K03158  TNFRSF1A, TNFR1; tumor necrosis factor receptor superfamily member 1A
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K08738  CYC; cytochrome c
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04534  GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
       K00922  PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
       K02649  PIK3R; phosphoinositide-3-kinase, regulatory subunit
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K02158  BAD; BCL2-antagonist of cell death
       K03161  TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
       K03160  TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
       K09565  PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
       K04180  CCR5; C-C chemokine receptor type 5
       K00461  ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
       K14151  ROP16; rhoptry protein 16
       K05443  IL10, CSIF; interleukin 10
       K05134  IL10RA; interleukin 10 receptor alpha
       K05135  IL10RB; interleukin 10 receptor beta
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
     05140 Leishmaniasis [PATH:ko05140]
     05142 Chagas disease (American trypanosomiasis) [PATH:ko05142]
     05143 African trypanosomiasis [PATH:ko05143]
 
   Drug resistance

[ BRITE | KEGG2 | KEGG ]
Last updated: July 20, 2014