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 Pathway module

   Energy metabolism

     Carbon fixation

       M00165  Reductive pentose phosphate cycle (Calvin cycle) [PATH:map00710]

       M00166  Reductive pentose phosphate cycle, RuBP + CO2 => glyceraldehyde-3P [PATH:map00710]

       M00167  Reductive pentose phosphate cycle, glyceraldehyde-3P => RuBP [PATH:map00710]

       M00168  CAM (Crassulacean acid metabolism), dark [PATH:map00710]

         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
         K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
         K00024  mdh; malate dehydrogenase [EC:1.1.1.37]

       M00169  CAM (Crassulacean acid metabolism), light [PATH:map00710]

       M00170  C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type [PATH:map00710]

         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K14454  GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
         K01610  E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]

       M00171  C4-dicarboxylic acid cycle, NAD+ -malic enzyme type [PATH:map00710]

         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K14454  GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
         K14455  GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
         K00025  MDH1; malate dehydrogenase [EC:1.1.1.37]
         K00026  MDH2; malate dehydrogenase [EC:1.1.1.37]
         K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
         K00028  E1.1.1.39; malate dehydrogenase (decarboxylating) [EC:1.1.1.39]
         K00814  GPT, ALT; alanine transaminase [EC:2.6.1.2]
         K14272  GGAT; glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44 2.6.1.-]
         K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]

       M00172  C4-dicarboxylic acid cycle, NADP+ -malic enzyme type [PATH:map00710]

         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K00051  E1.1.1.82; malate dehydrogenase (NADP+) [EC:1.1.1.82]
         K00029  E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
         K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]

       M00173  Reductive citric acid cycle (Arnon-Buchanan cycle) [PATH:map00720]

         K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
         K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
         K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
         K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
         K03737  nifJ; putative pyruvate-flavodoxin oxidoreductase [EC:1.2.7.-]
         K01007  pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]
         K01006  ppdK; pyruvate,orthophosphate dikinase [EC:2.7.9.1]
         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K01959  E6.4.1.1A, pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]
         K01960  E6.4.1.1B, pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]
         K01958  PC, pyc; pyruvate carboxylase [EC:6.4.1.1]
         K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
         K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
         K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
         K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
         K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
         K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
         K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
         K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
         K00242  sdhD; succinate dehydrogenase membrane anchor subunit
         K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
         K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
         K00246  frdC; fumarate reductase subunit C
         K00247  frdD; fumarate reductase subunit D
         K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
         K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
         K00174  korA; 2-oxoglutarate ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3]
         K00175  korB; 2-oxoglutarate ferredoxin oxidoreductase subunit beta [EC:1.2.7.3]
         K00177  korG; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
         K00176  korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
         K00031  IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]
         K01681  ACO, acnA; aconitate hydratase 1 / homoaconitase [EC:4.2.1.3 4.2.1.-]
         K01682  acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
         K15230  aclA; ATP-citrate lyase alpha-subunit [EC:2.3.3.8]
         K15231  aclB; ATP-citrate lyase beta-subunit [EC:2.3.3.8]
         K15232  ccsA; citryl-CoA synthetase large subunit [EC:6.2.1.18]
         K15233  ccsB; citryl-CoA synthetase small subunit
         K15234  ccl; citryl-CoA lyase [EC:4.1.3.34]

       M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway) [PATH:map00720]

       M00376  3-Hydroxypropionate bicycle [PATH:map00720]

       M00375  Hydroxypropionate-hydroxybutylate cycle [PATH:map00720]

       M00374  Dicarboxylate-hydroxybutyrate cycle [PATH:map00720]

         K00169  porA; pyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.1]
         K00170  porB; pyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.1]
         K00171  porD; pyruvate ferredoxin oxidoreductase, delta subunit [EC:1.2.7.1]
         K00172  porG; pyruvate ferredoxin oxidoreductase, gamma subunit [EC:1.2.7.1]
         K03737  nifJ; putative pyruvate-flavodoxin oxidoreductase [EC:1.2.7.-]
         K01007  pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]
         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
         K01676  E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2]
         K01679  E4.2.1.2B, fumC; fumarate hydratase, class II [EC:4.2.1.2]
         K01677  E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]
         K01678  E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]
         K00239  sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.99.1]
         K00240  sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.99.1]
         K00241  sdhC; succinate dehydrogenase cytochrome b556 subunit
         K00242  sdhD; succinate dehydrogenase membrane anchor subunit
         K00244  frdA; fumarate reductase flavoprotein subunit [EC:1.3.99.1]
         K00245  frdB; fumarate reductase iron-sulfur subunit [EC:1.3.99.1]
         K00246  frdC; fumarate reductase subunit C
         K00247  frdD; fumarate reductase subunit D
         K01902  sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
         K01903  sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
         K15038  K15038; succinyl-coA reductase [EC:1.2.1.76]
         K14465  K14465; succinate semialdehyde reductase (NADPH) [EC:1.1.1.-]
         K14466  K14466; 4-hydroxybutyryl-CoA synthetase (4-hydroxybutyrate-CoA ligase, AMP-forming) [EC:6.2.1.-]
         K14467  K14467; 4-hydroxybutyryl–CoA synthetase (4-hydroxybutyrate–CoA ligase, AMP-forming) [EC:6.2.1.-]
         K14534  abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
         K15016  K15016; 3-hydroxybutyryl-CoA dehydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.55 1.1.1.35]
         K01715  crt; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
         K01782  fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
         K01825  fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
         K07516  fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
         K00626  E2.3.1.9, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]

       M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:map00720]

     Nitrogen metabolism

     Methane metabolism

       M00347  Methanogenesis, formate => methane [PATH:map00680]

       M00567  Methanogenesis, CO2 => methane [PATH:map00680]

       M00356  Methanogenesis, methanol => methane [PATH:map00680]

       M00357  Methanogenesis, acetate => methane [PATH:map00680]

       M00563  Methanogenesis, methylamine => methane [PATH:map00680]

       M00562  Methanogenesis, dimethylamine => methane [PATH:map00680]

       M00561  Methanogenesis, trimethylamine => methane [PATH:map00680]

       M00358  Coenzyme M biosynthesis [PATH:map00680]

       M00174  Methane oxidation, methylotroph, methane => CO2 [PATH:map00680]

       M00346  Formaldehyde assimilation, serine pathway [PATH:map00680]

         K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
         K00830  AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
         K00018  hprA; glycerate dehydrogenase [EC:1.1.1.29]
         K11529  gk; glycerate 2-kinase [EC:2.7.1.165]
         K01689  ENO, eno; enolase [EC:4.2.1.11]
         K01595  ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
         K00024  mdh; malate dehydrogenase [EC:1.1.1.37]
         K08692  mtkB; malate-CoA ligase subunit alpha [EC:6.2.1.9]
         K14067  mtkA; malate-CoA ligase subunit beta [EC:6.2.1.9]
         K08691  mcl; malyl-CoA lyase [EC:4.1.3.24]

       M00345  Formaldehyde assimilation, ribulose monophosphate  pathway [PATH:map00680]

       M00344  Formaldehyde assimilation, xylulose monophosphate pathway [PATH:map00680]

       M00378  F420 biosynthesis [PATH:map00680]

       M00422  Acetyl-CoA pathway, CO2 => acetyl-CoA [PATH:map00680]

     Sulfur metabolism

   Carbohydrate and lipid metabolism

   Nucleotide and amino acid metabolism

   Secondary metabolism

 Structural complex

 Functional set

 Signature module

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Last updated: May 17, 2013