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 1. Oxidoreductases
 2. Transferases
   2.1  Transferring one-carbon groups
   2.2  Transferring aldehyde or ketonic groups
   2.3  Acyltransferases
   2.4  Glycosyltransferases
   2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.6  Transferring nitrogenous groups
   2.7  Transferring phosphorus-containing groups
     2.7.1  Phosphotransferases with an alcohol group as acceptor
     2.7.2  Phosphotransferases with a carboxy group as acceptor
     2.7.3  Phosphotransferases with a nitrogenous group as acceptor
     2.7.4  Phosphotransferases with a phosphate group as acceptor
     2.7.6  Diphosphotransferases
     2.7.7  Nucleotidyltransferases
     2.7.8  Transferases for other substituted phosphate groups
     2.7.9  Phosphotransferases with paired acceptors
     2.7.10  Protein-tyrosine kinases
     2.7.11  Protein-serine/threonine kinases  non-specific serine/threonine protein kinase
         K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:]
         K02214  CDC7; cell division control protein 7 [EC:]
         K02216  CHK1; serine/threonine-protein kinase Chk1 [EC:]
         K02218  CSNK1, CKI; casein kinase 1 [EC:]
         K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:]
         K03097  CSNK2A; casein kinase II subunit alpha [EC:]
         K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:]
         K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:]
         K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:]
         K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:]
         K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:]
         K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:]
         K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:]
         K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:]
         K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:]
         K04409  PAK1; p21-activated kinase 1 [EC:]
         K04410  PAK2; p21-activated kinase 2 [EC:]
         K04413  MINK; misshapen/NIK-related kinase [EC:]
         K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:]
         K04429  TAO; thousand and one amino acid protein kinase [EC:]
         K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:]
         K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:]
         K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:]
         K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:]
         K04456  AKT; RAC serine/threonine-protein kinase [EC:]
         K04514  ROCK1; Rho-associated protein kinase 1 [EC:]
         K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:]
         K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:]
         K04728  ATM, TEL1; ataxia telangiectasia mutated family protein [EC:]
         K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:]
         K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:]
         K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:]
         K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:]
         K04757  rsbW; serine/threonine-protein kinase RsbW [EC:]
         K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6 [EC:]
         K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:]
         K05688  PINK1; PTEN induced putative kinase 1 [EC:]
         K05733  PAK3, MRX30; p21-activated kinase 3 [EC:]
         K05734  PAK4; p21-activated kinase 4 [EC:]
         K05735  PAK6; p21-activated kinase 6 [EC:]
         K05736  PAK5, PAK7; p21-activated kinase 5 [EC:]
         K05743  LIMK1; LIM domain kinase 1 [EC:]
         K05744  LIMK2; LIM domain kinase 2 [EC:]
         K06103  CASK; calcium/calmodulin-dependent serine protein kinase [EC:]
         K06228  FU; fused [EC:]
         K06272  ILK; integrin-linked kinase [EC:]
         K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:]
         K06379  spoIIAB; stage II sporulation protein AB (anti-sigma F factor) [EC:]
         K06632  WEE1; wee1-like protein kinase [EC:]
         K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:]
         K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:]
         K06640  ATR; serine/threonine-protein kinase ATR [EC:]
         K06641  CHK2; serine/threonine-protein kinase Chk2 [EC:]
         K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:]
         K06683  CDC15; cell division control protein CDC15 [EC:]
         K07154  hipA; serine/threonine-protein kinase HipA [EC:]
         K07178  RIOK1; RIO kinase 1 [EC:]
         K07179  RIOK2; RIO kinase 2 [EC:]
         K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:]
         K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:]
         K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:]
         K08282  E2.7.11.1; non-specific serine/threonine protein kinase [EC:]
         K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:]
         K08788  DMPK; dystrophia myotonica-protein kinase [EC:]
         K08789  MAST; microtubule-associated serine/threonine kinase [EC:]
         K08790  STK38, NDR; serine/threonine kinase 38 [EC:]
         K08791  LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:]
         K08793  STK32, YANK; serine/threonine kinase 32 [EC:]
         K08796  BRSK; BR serine/threonine kinase [EC:]
         K08797  HUNK; hormonally upregulated Neu-associated kinase [EC:]
         K08798  MARK; MAP/microtubule affinity-regulating kinase [EC:]
         K08799  MELK; maternal embryonic leucine zipper kinase [EC:]
         K08800  NUAK; NUAK family, SNF1-like kinase [EC:]
         K08801  PASK; PAS domain containing serine/threonine kinase [EC:]
         K08802  SNRK; SNF related kinase [EC:]
         K08803  DAPK; death-associated protein kinase [EC:]
         K08804  STK17; serine/threonine kinase 17 [EC:]
         K08805  DCLK1_2; doublecortin-like kinase 1/2 [EC:]
         K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:]
         K08807  PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:]
         K08808  PSKH; protein serine kinase H [EC:]
         K08809  SPEG; striated muscle-specific serine/threonine protein kinase [EC:]
         K08810  TRIO; triple functional domain protein [EC:]
         K08811  TSSK, STK22; testis-specific serine kinase [EC:]
         K08813  STK33; serine/threonine kinase 33 [EC:]
         K08816  VRK; vaccinia related kinase [EC:]
         K08826  HIPK; homeodomain interacting protein kinase [EC:]
         K08827  PRPF4B; serine/threonine-protein kinase PRP4 [EC:]
         K08831  SRPK2; serine/threonine-protein kinase SRPK2 [EC:]
         K08832  SRPK3, STK23; serine/threonine-protein kinase SRPK3 [EC:]
         K08833  MAP4K5, KHS1; mitogen-activated protein kinase kinase kinase kinase 5 [EC:]
         K08834  MYO3, DFNB30; myosin III [EC:]
         K08835  OXSR1, STK39; serine/threonine-protein kinase OSR1/STK39 [EC:]
         K08836  SLK; STE20-like kinase [EC:]
         K08837  STK10, LOK; serine/threonine kinase 10 [EC:]
         K08838  STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:]
         K08840  TNIK; TRAF2 and NCK interacting kinase [EC:]
         K08843  LRRK1; leucine-rich repeat kinase 1 [EC:]
         K08844  LRRK2; leucine-rich repeat kinase 2 [EC:]
         K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:]
         K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:]
         K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:]
         K08848  RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:]
         K08849  MLKL; mixed lineage kinase domain-like [EC:]
         K08850  AURKX; aurora kinase, other [EC:]
         K08851  TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:]
         K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC: 3.1.26.-]
         K08853  AAK; AP2-associated kinase [EC:]
         K08854  BMP2K, BIKE; BMP2 inducible kinase [EC:]
         K08855  GAK; cyclin G-associated kinase [EC:]
         K08856  STK16; serine/threonine kinase 16 [EC:]
         K08857  NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:]
         K08858  SBK; serine/threonine-protein kinase SBK [EC:]
         K08859  STK35, PDIK1, CLIK1; serine/threonine kinase 35 [EC:]
         K08860  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:]
         K08864  TLK; tousled-like kinase [EC:]
         K08867  WNK, PRKWNK; WNK lysine deficient protein kinase [EC:]
         K08872  RIOK3, SUDD; RIO kinase 3 [EC:]
         K08873  SMG1; serine/threonine-protein kinase SMG1 [EC:]
         K08877  UHMK1, KIS; U2AF homology motif (UHM) kinase 1 [EC:]
         K08878  BCR1, BCR; breakpoint cluster region protein [EC:]
         K08880  STK19; serine/threonine kinase 19 [EC:]
         K08884  K08884; serine/threonine protein kinase, bacterial [EC:]
         K08886  TNK2, ACK1; activated CDC42 kinase 1 [EC:]
         K08957  CSNK1A; casein kinase 1, alpha [EC:]
         K08958  CSNK1G; casein kinase 1, gamma [EC:]
         K08959  CSNK1D; casein kinase 1, delta [EC:]
         K08960  CSNK1E; casein kinase 1, epsilon [EC:]
         K11479  AURKB; aurora kinase B [EC:]
         K11480  AURKC; aurora kinase C [EC:]
         K11481  AURKA; aurora kinase A [EC:]
         K11715  ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC: 3.1.26.-]
         K11889  impN; type VI secretion system protein ImpN [EC:]
         K11912  ppkA; serine/threonine-protein kinase PpkA [EC:]
         K12132  prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:]
         K12567  TTN; titin [EC:]
         K12761  SNF1; carbon catabolite-derepressing protein kinase [EC:]
         K12765  IME2; meiosis induction protein kinase IME2/SME1 [EC:]
         K12766  MDS1, RIM11; serine/threonine-protein kinase MDS1/RIM11 [EC:]
         K12767  RIM15; serine/threonine-protein kinase RIM15 [EC:]
         K12771  SPS1; sporulation-specific protein 1 [EC:]
         K12776  MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:]
         K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:]
         K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:]
         K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:]
         K13412  CPK; calcium-dependent protein kinase [EC:]
         K13415  BRI1; protein brassinosteroid insensitive 1 [EC:]
         K13416  BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:]
         K13417  SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:]
         K13418  SERK1; somatic embryogenesis receptor kinase 1 [EC:]
         K13419  pknK; serine/threonine-protein kinase PknK [EC:]
         K13420  FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [EC:]
         K13428  EFR; LRR receptor-like serine/threonine-protein kinase EFR [EC:]
         K13430  PBS1; serine/threonine-protein kinase PBS1 [EC:]
         K13436  PTI1; pto-interacting protein 1 [EC:]
         K14498  SNRK2; serine/threonine-protein kinase SRK2 [EC:]
         K14500  BSK; BR-signaling kinase [EC:]
         K14502  BIN2; protein brassinosteroid insensitive 2 [EC:]
         K14510  CTR1; serine/threonine-protein kinase CTR1 [EC:]
         K14758  HRR25; casein kinase I homolog HRR25 [EC:]
         K14949  pknG; serine/threonine-protein kinase PknG [EC:]
         K15048  KALRN; kalirin [EC:]
         K15409  SRPK1; serine/threonine-protein kinase SRPK1 [EC:]
         K15904  kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:]
         K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:]
         K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:]
         K16196  EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:]
         K16279  KEG; E3 ubiquitin-protein ligase KEG [EC:]
         K16288  RIPK5, DSTYK; receptor-interacting serine/threonine-protein kinase 5 [EC:]
         K16289  ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:]
         K16307  CDC42BP; serine/threonine-protein kinase MRCK [EC:]
         K16308  CIT; citron Rho-interacting kinase [EC:]
         K16309  MASTL, GW; serine/threonine-protein kinase greatwall [EC:]
         K16310  NIM1; serine/threonine-protein kinase NIM1 [EC:]
         K16311  SIK2; serine/threonine-protein kinase SIK2 [EC:]
         K16312  STK40, SHIK; serine/threonine-protein kinase 40 [EC:]
         K16313  NRK; Nik-related protein kinase [EC:]
         K16314  ELM1; serine/threonine-protein kinase ELM1 [EC:]
         K16315  GSG2; serine/threonine-protein kinase haspin [EC:]
         K16316  STK31, TDRD8; serine/threonine-protein kinase 31 [EC:]
         K16510  RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:]
         K17388  ROCK2; Rho-associated protein kinase 2 [EC:]
         K17529  SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:]
         K17530  DCLK3; doublecortin-like kinase 3 [EC:]
         K17531  OBSCN, ARHGEF30; obscurin-RhoGEF [EC:]
         K17535  TNNI3K; serine/threonine-protein kinase TNNI3K [EC:]
         K17539  PDIK1L, CLIK1L; serine/threonine-protein kinase PDIK1L [EC:]
         K17545  ULK4; serine/threonine-protein kinase ULK4 [EC:]
         K17752  rsbT; serine/threonine-protein kinase RsbT [EC:]
         K18529  KSR2; kinase suppressor of Ras 2 [EC:]
         K18639  KCC4; serine/threonine-protein kinase KCC4 [EC:]
         K18679  CDR2; mitosis inducer protein kinase Cdr2 [EC:]
         K18680  CDR1; mitosis inducer protein kinase Cdr1 [EC:]
         K19008  SIK1; serine/threonine-protein kinase SIK1 [EC:]
         K19009  SIK3; serine/threonine-protein kinase SIK3 [EC:]
         K19439  US3; serine/threonine-protein kinase US3 [EC:]
         K19440  UL13; serine/threonine-protein kinase UL13 [EC:]
         K19455  BGLF4; serine/threonine-protein kinase BGLF4 [EC:]
         K19800  SCH9; serine/threonine protein kinase SCH9 [EC:]
         K19830  YCK3; casein kinase I homolog 3 [EC:]
         K19833  CLA4; serine/threonine-protein kinase CLA4 [EC:]
         K19852  KIN1_2; serine/threonine protein kinase KIN1/2 [EC:]
         K20714  OXI1; serine/threonine-protein kinase OXI1 [EC:]
         K20715  PHOT; phototropin [EC:]
         K20718  ER; LRR receptor-like serine/threonine-protein kinase ERECTA [EC:]
         K20872  NEK2; NIMA (never in mitosis gene a)-related kinase 2 [EC:]
         K20873  NEK3; NIMA (never in mitosis gene a)-related kinase 3 [EC:]
         K20875  NEK6; NIMA (never in mitosis gene a)-related kinase 6 [EC:]
         K20876  NEK7; NIMA (never in mitosis gene a)-related kinase 7 [EC:]
         K20877  NEK8; NIMA (never in mitosis gene a)-related kinase 8 [EC:]
         K20878  NEK9, NERCC1; NIMA (never in mitosis gene a)-related kinase 9 [EC:]
         K20879  NEK10; NIMA (never in mitosis gene a)-related kinase 10 [EC:]
         K20880  NEK11; NIMA (never in mitosis gene a)-related kinase 11 [EC:]
         K21157  SAK1; SNF1-activating kinase 1 [EC:]
         K21158  TOS3; serine/threonine-protein kinase TOS3 [EC:]
         K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:]
         K21358  ULK3; serine/threonine-protein kinase ULK3 [EC:]
         K21506  VPK1; serine/threonine-protein kinase 1 [EC:]
         K21518  VPK2; serine/threonine-protein kinase 2 [EC:]
         K21958  FAM20C; extracellular serine/threonine protein kinase FAM20C [EC:]
         K22008  PSK1; serine/threonine-protein kinase Psk1 [EC:]  [pyruvate dehydrogenase (acetyl-transferring)] kinase  dephospho-[reductase kinase] kinase  [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase  [isocitrate dehydrogenase (NADP+)] kinase  [tyrosine 3-monooxygenase] kinase  myosin-heavy-chain kinase  Fas-activated serine/threonine kinase  Goodpasture-antigen-binding protein kinase  IkappaB kinase  cAMP-dependent protein kinase  cGMP-dependent protein kinase  protein kinase C  rhodopsin kinase  beta-adrenergic-receptor kinase  G-protein-coupled receptor kinase  Ca2+/calmodulin-dependent protein kinase  myosin-light-chain kinase  phosphorylase kinase  elongation factor 2 kinase  polo kinase  cyclin-dependent kinase  [RNA-polymerase]-subunit kinase  mitogen-activated protein kinase  mitogen-activated protein kinase kinase kinase  tau-protein kinase  [acetyl-CoA carboxylase] kinase  tropomyosin kinase  low-density-lipoprotein receptor kinase  receptor protein serine/threonine kinase  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase  [pyruvate, phosphate dikinase] kinase  [pyruvate, water dikinase] kinase
     2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
     2.7.13  Protein-histidine kinases
     2.7.14  Protein-arginine kinases
     2.7.99  Other protein kinases
     2.7.-  Transferring phosphorus-containing groups
   2.8  Transferring sulfur-containing groups
   2.9  Transferring selenium-containing groups
   2.10  Transferring molybdenum- or tungsten-containing groups
 3. Hydrolases
 4. Lyases
 5. Isomerases
 6. Ligases

Last updated: March 20, 2018
EC number data are obtained from ExplorEnz