Enzymes

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 1. Oxidoreductases
 
 2. Transferases
 
 3. Hydrolases
 
 4. Lyases
 
 5. Isomerases
 
 6. Ligases
   6.1  Forming carbon-oxygen bonds
   6.2  Forming carbon-sulfur bonds
   6.3  Forming carbon-nitrogen bonds
     6.3.1  Acid-D-ammonia (or amine) ligases (amide synthases)
     6.3.2  Acid-D-amino-acid ligases (peptide synthases)
     6.3.3  Cyclo-ligases
     6.3.4  Other carbon-nitrogen ligases
       6.3.4.2  CTP synthase (glutamine hydrolysing)
       6.3.4.3  formate---tetrahydrofolate ligase
       6.3.4.4  adenylosuccinate synthase
       6.3.4.5  argininosuccinate synthase
       6.3.4.6  urea carboxylase
       6.3.4.7  ribose-5-phosphate---ammonia ligase
       6.3.4.8  imidazoleacetate---phosphoribosyldiphosphate ligase
       6.3.4.9  biotin---[methylmalonyl-CoA-carboxytransferase] ligase
       6.3.4.10  biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase
       6.3.4.11  biotin---[methylcrotonoyl-CoA-carboxylase] ligase
       6.3.4.12  glutamate---methylamine ligase
       6.3.4.13  phosphoribosylamine---glycine ligase
       6.3.4.14  biotin carboxylase
         K01961  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
         K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
         K11263  bccA; acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.3.4.14]
       6.3.4.15  biotin---[acetyl-CoA-carboxylase] ligase
       6.3.4.16  carbamoyl-phosphate synthase (ammonia)
       6.3.4.17  formate---dihydrofolate ligase
       6.3.4.18  5-(carboxyamino)imidazole ribonucleotide synthase
       6.3.4.19  tRNAIle-lysidine synthase
       6.3.4.20  7-cyano-7-deazaguanine synthase
       6.3.4.21  nicotinate phosphoribosyltransferase
       6.3.4.22  tRNAIle2-agmatinylcytidine synthase
       6.3.4.23  formate---phosphoribosylaminoimidazolecarboxamide ligase
       6.3.4.-  
     6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
     6.3.-  Forming carbon-nitrogen bonds
   6.4  Forming carbon-carbon bonds
     6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
       6.4.1.1  pyruvate carboxylase
       6.4.1.2  acetyl-CoA carboxylase
         K01961  accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
         K01962  accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2]
         K01963  accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2]
         K01964  K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
         K11262  ACAC; acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14]
         K15036  K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
       6.4.1.3  propionyl-CoA carboxylase
       6.4.1.4  methylcrotonoyl-CoA carboxylase
       6.4.1.5  geranoyl-CoA carboxylase
       6.4.1.6  acetone carboxylase
       6.4.1.7  2-oxoglutarate carboxylase
       6.4.1.8  acetophenone carboxylase
       6.4.1.-  
     6.4.-  Forming carbon-carbon bonds
   6.5  Forming phosphoric-ester bonds
   6.6  Forming nitrogen-D-metal bonds
   6.-