1. Oxidoreductases

 2. Transferases

   2.1  Transferring one-carbon groups

     2.1.1  Methyltransferases

       2.1.1.1  nicotinamide N-methyltransferase

       2.1.1.2  guanidinoacetate N-methyltransferase

       2.1.1.3  thetin---homocysteine S-methyltransferase

       2.1.1.4  acetylserotonin O-methyltransferase

       2.1.1.5  betaine---homocysteine S-methyltransferase

       2.1.1.6  catechol O-methyltransferase

       2.1.1.7  nicotinate N-methyltransferase

       2.1.1.8  histamine N-methyltransferase

       2.1.1.9  thiol S-methyltransferase

       2.1.1.10  homocysteine S-methyltransferase

       2.1.1.11  magnesium protoporphyrin IX methyltransferase

       2.1.1.12  methionine S-methyltransferase

       2.1.1.13  methionine synthase

       2.1.1.14  5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase

       2.1.1.15  fatty-acid O-methyltransferase

       2.1.1.16  methylene-fatty-acyl-phospholipid synthase

       2.1.1.17  phosphatidylethanolamine N-methyltransferase

       2.1.1.18  polysaccharide O-methyltransferase

       2.1.1.19  trimethylsulfonium---tetrahydrofolate N-methyltransferase

       2.1.1.20  glycine N-methyltransferase

       2.1.1.21  methylamine---glutamate N-methyltransferase

       2.1.1.22  carnosine N-methyltransferase

       2.1.1.25  phenol O-methyltransferase

       2.1.1.26  iodophenol O-methyltransferase

       2.1.1.27  tyramine N-methyltransferase

       2.1.1.28  phenylethanolamine N-methyltransferase

       2.1.1.33  tRNA (guanine46-N7)-methyltransferase

       2.1.1.34  tRNA (guanosine18-2'-O)-methyltransferase

       2.1.1.35  tRNA (uracil54-C5)-methyltransferase

       2.1.1.37  DNA (cytosine-5-)-methyltransferase

       2.1.1.38  O-demethylpuromycin O-methyltransferase

       2.1.1.39  inositol 3-methyltransferase

       2.1.1.40  inositol 1-methyltransferase

       2.1.1.41  sterol 24-C-methyltransferase

       2.1.1.42  flavone 3'-O-methyltransferase

       2.1.1.43  histone-lysine N-methyltransferase

       2.1.1.44  dimethylhistidine N-methyltransferase

       2.1.1.45  thymidylate synthase

       2.1.1.46  isoflavone 4'-O-methyltransferase

       2.1.1.47  indolepyruvate C-methyltransferase

       2.1.1.49  amine N-methyltransferase

       2.1.1.50  loganate O-methyltransferase

       2.1.1.53  putrescine N-methyltransferase

       2.1.1.54  deoxycytidylate C-methyltransferase

       2.1.1.55  tRNA (adenine-N6-)-methyltransferase

       2.1.1.56  mRNA (guanine-N7)-methyltransferase

       2.1.1.57  mRNA (nucleoside-2'-O)-methyltransferase

       2.1.1.59  [cytochrome c]-lysine N-methyltransferase

       2.1.1.60  calmodulin-lysine N-methyltransferase

       2.1.1.61  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase

       2.1.1.62  mRNA (2'-O-methyladenosine-N6-)-methyltransferase

       2.1.1.63  methylated-DNA---[protein]-cysteine S-methyltransferase

       2.1.1.64  3-demethylubiquinol 3-O-methyltransferase

       2.1.1.65  licodione 2'-O-methyltransferase

       2.1.1.66  rRNA (adenosine-2'-O-)-methyltransferase

       2.1.1.67  thiopurine S-methyltransferase

       2.1.1.68  caffeate O-methyltransferase

       2.1.1.69  5-hydroxyfuranocoumarin 5-O-methyltransferase

       2.1.1.70  8-hydroxyfuranocoumarin 8-O-methyltransferase

       2.1.1.71  phosphatidyl-N-methylethanolamine N-methyltransferase

       2.1.1.72  site-specific DNA-methyltransferase (adenine-specific)

       2.1.1.74  methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase (FADH2-oxidizing)

       2.1.1.75  apigenin 4'-O-methyltransferase

       2.1.1.76  quercetin 3-O-methyltransferase

       2.1.1.77  protein-L-isoaspartate(D-aspartate) O-methyltransferase

       2.1.1.78  isoorientin 3'-O-methyltransferase

       2.1.1.79  cyclopropane-fatty-acyl-phospholipid synthase

       2.1.1.80  protein-glutamate O-methyltransferase

       2.1.1.82  3-methylquercetin 7-O-methyltransferase

       2.1.1.83  3,7-dimethylquercetin 4'-O-methyltransferase

       2.1.1.84  methylquercetagetin 6-O-methyltransferase

       2.1.1.85  protein-histidine N-methyltransferase

       2.1.1.86  tetrahydromethanopterin S-methyltransferase

       2.1.1.87  pyridine N-methyltransferase

       2.1.1.88  8-hydroxyquercetin 8-O-methyltransferase

       2.1.1.89  tetrahydrocolumbamine 2-O-methyltransferase

       2.1.1.90  methanol---corrinoid protein Co-methyltransferase

       2.1.1.91  isobutyraldoxime O-methyltransferase

       2.1.1.94  tabersonine 16-O-methyltransferase

       2.1.1.95  tocopherol O-methyltransferase

       2.1.1.96  thioether S-methyltransferase

       2.1.1.97  3-hydroxyanthranilate 4-C-methyltransferase

       2.1.1.98  diphthine synthase

       2.1.1.99  3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase

       2.1.1.100  protein-S-isoprenylcysteine O-methyltransferase

       2.1.1.101  macrocin O-methyltransferase

       2.1.1.102  demethylmacrocin O-methyltransferase

       2.1.1.103  phosphoethanolamine N-methyltransferase

       2.1.1.104  caffeoyl-CoA O-methyltransferase

       2.1.1.105  N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase

       2.1.1.106  tryptophan 2-C-methyltransferase

       2.1.1.107  uroporphyrinogen-III C-methyltransferase

       2.1.1.108  6-hydroxymellein O-methyltransferase

       2.1.1.109  demethylsterigmatocystin 6-O-methyltransferase

       2.1.1.110  sterigmatocystin 8-O-methyltransferase

       2.1.1.111  anthranilate N-methyltransferase

       2.1.1.112  glucuronoxylan 4-O-methyltransferase

       2.1.1.113  site-specific DNA-methyltransferase (cytosine-N4-specific)

       2.1.1.114  polyprenyldihydroxybenzoate methyltransferase

       2.1.1.115  (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase

       2.1.1.116  3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase

       2.1.1.117  (S)-scoulerine 9-O-methyltransferase

       2.1.1.118  columbamine O-methyltransferase

       2.1.1.119  10-hydroxydihydrosanguinarine 10-O-methyltransferase

       2.1.1.120  12-hydroxydihydrochelirubine 12-O-methyltransferase

       2.1.1.121  6-O-methylnorlaudanosoline 5'-O-methyltransferase

       2.1.1.122  (S)-tetrahydroprotoberberine N-methyltransferase

       2.1.1.123  [cytochrome-c]-methionine S-methyltransferase

       2.1.1.124  [cytochrome c]-arginine N-methyltransferase

       2.1.1.125  histone-arginine N-methyltransferase

       2.1.1.126  [myelin basic protein]-arginine N-methyltransferase

       2.1.1.127  [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase

       2.1.1.128  (RS)-norcoclaurine 6-O-methyltransferase

       2.1.1.129  inositol 4-methyltransferase

       2.1.1.130  precorrin-2 C20-methyltransferase

       2.1.1.131  precorrin-3B C17-methyltransferase

       2.1.1.132  precorrin-6B C5,15-methyltransferase (decarboxylating)

       2.1.1.133  precorrin-4 C11-methyltransferase

       2.1.1.136  chlorophenol O-methyltransferase

       2.1.1.137  arsenite methyltransferase

       2.1.1.139  3'-demethylstaurosporine O-methyltransferase

       2.1.1.140  (S)-coclaurine-N-methyltransferase

       2.1.1.141  jasmonate O-methyltransferase

       2.1.1.142  cycloartenol 24-C-methyltransferase

       2.1.1.143  24-methylenesterol C-methyltransferase

       2.1.1.144  trans-aconitate 2-methyltransferase

       2.1.1.145  trans-aconitate 3-methyltransferase

       2.1.1.146  (iso)eugenol O-methyltransferase

       2.1.1.147  corydaline synthase

       2.1.1.148  thymidylate synthase (FAD)

       2.1.1.150  isoflavone 7-O-methyltransferase

       2.1.1.151  cobalt-factor II C20-methyltransferase

       2.1.1.152  precorrin-6A synthase (deacetylating)

       2.1.1.153  vitexin 2''-O-rhamnoside 7-O-methyltransferase

       2.1.1.154  isoliquiritigenin 2'-O-methyltransferase

       2.1.1.155  kaempferol 4'-O-methyltransferase

       2.1.1.156  glycine/sarcosine N-methyltransferase

       2.1.1.157  sarcosine/dimethylglycine N-methyltransferase

       2.1.1.158  7-methylxanthosine synthase

       2.1.1.159  theobromine synthase

       2.1.1.160  caffeine synthase

       2.1.1.161  dimethylglycine N-methyltransferase

       2.1.1.162  glycine/sarcosine/dimethylglycine N-methyltransferase

       2.1.1.163  demethylmenaquinone methyltransferase

       2.1.1.164  demethylrebeccamycin-D-glucose O-methyltransferase

       2.1.1.165  methyl halide transferase

       2.1.1.166  23S rRNA (uridine2552-2'-O)-methyltransferase

       2.1.1.167  27S pre-rRNA (guanosine2922-2'-O)-methyltransferase

       2.1.1.168  21S rRNA (uridine2791-2'-O)-methyltransferase

       2.1.1.169  tricetin 3',4',5'-O-trimethyltransferase

       2.1.1.170  16S rRNA (guanine527-N7)-methyltransferase

       2.1.1.171  16S rRNA (guanine966-N2)-methyltransferase

       2.1.1.172  16S rRNA (guanine1207-N2)-methyltransferase

       2.1.1.173  23S rRNA (guanine2445-N2)-methyltransferase

       2.1.1.174  23S rRNA (guanine1835-N2)-methyltransferase

       2.1.1.175  tricin synthase

       2.1.1.176  16S rRNA (cytosine967-C5)-methyltransferase

       2.1.1.177  23S rRNA (pseudouridine1915-N3)-methyltransferase

       2.1.1.178  16S rRNA (cytosine1407-C5)-methyltransferase

       2.1.1.179  16S rRNA (guanine1405-N7)-methyltransferase

       2.1.1.180  16S rRNA (adenine1408-N1)-methyltransferase

       2.1.1.181  23S rRNA (adenine1618-N6)-methyltransferase

       2.1.1.182  16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase

       2.1.1.183  18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase

       2.1.1.184  23S rRNA (adenine2085-N6)-dimethyltransferase

       2.1.1.185  23S rRNA (guanosine2251-2'-O)-methyltransferase

       2.1.1.186  23S rRNA (cytidine2498-2'-O)-methyltransferase

       2.1.1.187  23S rRNA (guanine745-N1)-methyltransferase

       2.1.1.188  23S rRNA (guanine748-N1)-methyltransferase

       2.1.1.189  23S rRNA (uracil747-C5)-methyltransferase

       2.1.1.190  23S rRNA (uracil1939-C5)-methyltransferase

       2.1.1.191  23S rRNA (cytosine1962-C5)-methyltransferase

       2.1.1.192  23S rRNA (adenine2503-C2)-methyltransferase

       2.1.1.193  16S rRNA (uracil1498-N3)-methyltransferase

       2.1.1.195  cobalt-precorrin-5B (C1)-methyltransferase

       2.1.1.196  cobalt-precorrin-7 (C15)-methyltransferase [decarboxylating]

       2.1.1.197  malonyl-CoA O-methyltransferase

       2.1.1.198  16S rRNA (cytidine1402-2'-O)-methyltransferase

       2.1.1.199  16S rRNA (cytosine1402-N4)-methyltransferase

       2.1.1.200  tRNA (cytidine32/uridine32-2'-O)-methyltransferase

       2.1.1.201  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase

       2.1.1.202  multisite-specific tRNA:(cytosine-C5)-methyltransferase

       2.1.1.203  tRNA (cytosine34-C5)-methyltransferase

       2.1.1.204  tRNA (cytosine38-C5)-methyltransferase

       2.1.1.205  tRNA (cytidine32/guanosine34-2'-O)-methyltransferase

       2.1.1.206  tRNA (cytidine56-2'-O)-methyltransferase

       2.1.1.207  tRNA (cytidine34-2'-O)-methyltransferase

       2.1.1.208  23S rRNA (uridine2479-2'-O)-methyltransferase

       2.1.1.209  23S rRNA (guanine2535-N1)-methyltransferase

       2.1.1.210  demethylspheroidene O-methyltransferase

       2.1.1.211  tRNASer (uridine44-2'-O)-methyltransferase

       2.1.1.212  2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase

       2.1.1.213  tRNA (guanine10-N2)-dimethyltransferase

       2.1.1.214  tRNA (guanine10-N2)-methyltransferase

       2.1.1.215  tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase

       2.1.1.216  tRNA (guanine26-N2)-dimethyltransferase

       2.1.1.217  tRNA (adenine22-N1)-methyltransferase

       2.1.1.218  tRNA (adenine9-N1)-methyltransferase

       2.1.1.219  tRNA (adenine57-N1/adenine58-N1)-methyltransferase

       2.1.1.220  tRNA (adenine58-N1)-methyltransferase

       2.1.1.221  tRNA (guanine9-N1)-methyltransferase

       2.1.1.222  2-polyprenyl-6-hydroxyphenyl methylase

       2.1.1.223  tRNA1Val (adenine37-N6)-methyltransferase

       2.1.1.224  23S rRNA (adenine2503-C8)-methyltransferase

       2.1.1.225  tRNA:m4X modification enzyme

       2.1.1.226  23S rRNA (cytidine1920-2'-O)-methyltransferase

       2.1.1.227  16S rRNA (cytidine1409-2'-O)-methyltransferase

       2.1.1.228  tRNA (guanine37-N1)-methyltransferase

       2.1.1.229  tRNA (carboxymethyluridine34-5-O)-methyltransferase

       2.1.1.230  23S rRNA (adenosine1067-2'-O)-methyltransferase

       2.1.1.231  flavonoid 4'-O-methyltransferase

       2.1.1.232  naringenin 7-O-methyltransferase

       2.1.1.233  [phosphatase 2A protein]-leucine-carboxy methyltransferase

       2.1.1.234  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

       2.1.1.235  dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase

       2.1.1.236  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase

       2.1.1.237  mycinamicin III 3''-O-methyltransferase

       2.1.1.238  mycinamicin VI 2''-O-methyltransferase

       2.1.1.239  L-olivosyl-oleandolide 3-O-methyltransferase

       2.1.1.240  trans-resveratrol di-O-methyltransferase

       2.1.1.241  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase

       2.1.1.242  16S rRNA (guanine1516-N2)-methyltransferase

       2.1.1.243  2-ketoarginine methyltransferase

       2.1.1.244  protein N-terminal methyltransferase

       2.1.1.245  5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase

       2.1.1.246  [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase

       2.1.1.247  [methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase

       2.1.1.248  methylamine---corrinoid protein Co-methyltransferase

       2.1.1.249  dimethylamine---corrinoid protein Co-methyltransferase

       2.1.1.250  trimethylamine---corrinoid protein Co-methyltransferase

       2.1.1.251  methylated-thiol---coenzyme M methyltransferase

       2.1.1.252  tetramethylammonium---corrinoid protein Co-methyltransferase

       2.1.1.253  [methyl-Co(III) tetramethylammonium-specific corrinoid protein]:coenzyme M methyltransferase

       2.1.1.254  erythromycin 3''-O-methyltransferase

       2.1.1.255  geranyl diphosphate 2-C-methyltransferase

       2.1.1.256  tRNA (guanine6-N2)-methyltransferase

       2.1.1.257  tRNA (pseudouridine54-N1)-methyltransferase

       2.1.1.258  5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase

       2.1.1.259  [fructose-bisphosphate aldolase]-lysine N-methyltransferase

       2.1.1.260  rRNA small subunit pseudouridine methyltransferase Nep1

       2.1.1.261  4-dimethylallyltryptophan N-methyltransferase

       2.1.1.262  squalene methyltransferase

       2.1.1.263  botryococcene C-methyltransferase

       2.1.1.264  23S rRNA (guanine2069-N7)-methyltransferase

       2.1.1.265  tellurite methyltransferase

       2.1.1.266  23S rRNA (adenine2030-N6)-methyltransferase

       2.1.1.267  flavonoid 3',5'-methyltransferase

       2.1.1.268  tRNAThr (cytosine32-N3)-methyltransferase

       2.1.1.-  

     2.1.2  Hydroxymethyl-, formyl- and related transferases

     2.1.3  Carboxy- and carbamoyltransferases

     2.1.4  Amidinotransferases

     2.1.-  Transferring one-carbon groups

   2.2  Transferring aldehyde or ketonic groups

   2.3  Acyltransferases

   2.4  Glycosyltransferases

   2.5  Transferring alkyl or aryl groups, other than methyl groups

   2.6  Transferring nitrogenous groups

   2.7  Transferring phosphorus-containing groups

   2.8  Transferring sulfur-containing groups

   2.9  Transferring selenium-containing groups

   2.10  Transferring molybdenum- or tungsten-containing groups

   2.-  

 3. Hydrolases

 4. Lyases

 5. Isomerases

 6. Ligases