Transporters

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 ABC Transporters, Eukaryotic Type
 
 ABC Transporters, Prokaryotic Type
 
 Solute Carrier Family (SLC)
 
 Major Facilitator Superfamily (MFS)
 
 Phosphotransferase System (PTS)
 
 Other Transporters
   Aquaporins and small neutral solute transporters [TC:1.A.8]
   Pores ion channels [TC:1]
     K10716  kch, trkA, mthK, pch; voltage-gated potassium channel
     K21867  AKT, KAT, GORK, SKOR; potassium channel
     K21862  DSC1, NaCP60E; voltage-gated cation channel
     K21864  CCH1; voltage-dependent calcium channel
     K08714  VGSC; voltage-gated sodium channel
     K21866  POLLUX, DMI1, CASTOR; ion channel POLLUX/CASTOR
     K08713  lctB; potassium channel LctB
     K08715  IRPC; inward rectifier potassium channel
     K03320  amt, AMT, MEP; ammonium transporter, Amt family
     K06579  RH, CD240; Rhesus blood group glycoprotein
     K21888  DHAR; glutathione dehydrogenase/transferase [EC:1.8.5.1 2.5.1.18]
     K00799  GST, gst; glutathione S-transferase [EC:2.5.1.18]
     K03599  sspA, mglA; stringent starvation protein A
     K07114  yfbK; Ca-activated chloride channel homolog
     K21889  TMBIM6, BI1, TEGT; Bax inhibitor 1
     K21890  GHITM, DERP2, TMBIM5; growth hormone-inducible transmembrane protein
     K19416  yccA; modulator of FtsH protease
     K06212  focA; formate transporter
     K03459  focB; formate transporter
     K21993  fdhC; formate transporter
     K02598  nirC; nitrite transporter
     K21988  TMC; transmembrane channel-like protein
     K21989  TMEM63; calcium permeable stress-gated cation channel
     K15464  BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
     K15465  BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
     K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
     K02159  BAX; apoptosis regulator BAX
     K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
     K02163  BCLW; apoptosis regulator BCL-W
     K20094  CED-9; cell death protein 9
     K03282  mscL; large conductance mechanosensitive channel
     K05802  mscK, kefA, aefA; potassium-dependent mechanosensitive channel
     K22051  mscM, bspA; miniconductance mechanosensitive channel
     K03442  mscS; small conductance mechanosensitive channel
     K22044  ybiO; moderate conductance mechanosensitive channel
     K16052  ynaI, mscMJ; MscS family membrane protein
     K16053  ybdG, mscM; miniconductance mechanosensitive channel
     K22047  MSL1_2_3; mechanosensitive ion channel protein 1/2/3
     K22048  MSL4S; mechanosensitive ion channel protein 4/5/6/7/8/9/10
     K07372  GJA1, CX43; gap junction alpha-1 protein
     K07612  GJA3, CX46; gap junction alpha-3 protein
     K07613  GJA4, CX37; gap junction alpha-4 protein
     K07617  GJA8, CX50; gap junction alpha-8 protein
     K07620  GJB1, CX32; gap junction beta-1 protein
     K07621  GJB2, CX26; gap junction beta-2 protein
     K07622  GJB3, CX31; gap junction beta-3 protein
     K07616  GJC1, GJA7, CX45; gap junction gamma-1 protein
     K07619  GJC2, GJA12, CX47; gap junction gamma-2 protein
     K07628  GJC3, GJE1, CX29; gap junction gamma-3 protein
     K07373  GJD2, CX36; gap junction delta-2 protein
     K07630  GJD4; gap junction delta-4 protein
     K22039  GJE1, CX23; gap junction epsilon-1 protein
     K22037  inx, zpg, ogre, shakB; innexin
     K03443  PANX1; pannexin 1
     K20857  PANX2_3; pannexin 2/3
     K22038  LRRC8; volume-regulated anion channel
     K06213  mgtE; magnesium transporter
     K07244  K07244; mgtE-like transporter
     K13360  FXYD1, PLM; FXYD domain-containing ion transport regulator 1
     K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
     K13361  FXYD3, MAT8; FXYD domain-containing ion transport regulator 3
     K13359  FXYD4, CHIF; FXYD domain containing ion transport regulator 4
     K13362  FXYD5, DYSAD; FXYD domain-containing ion transport regulator 5
     K13363  FXYD6; FXYD domain-containing ion transport regulator 6
     K08717  utp; urea transporter
     K22112  amiS; putative amide transporter protein
     K03191  ureI; acid-activated urea channel
     K02556  motA; chemotaxis protein MotA
     K02557  motB; chemotaxis protein MotB
     K21217  motX; sodium-type polar flagellar protein MotX
     K21218  motY; sodium-type flagellar protein MotY
     K03561  exbB; biopolymer transport protein ExbB
     K03559  exbD; biopolymer transport protein ExbD
     K03562  tolQ; biopolymer transport protein TolQ
     K03560  tolR; biopolymer transport protein TolR
     K03284  corA; magnesium transporter
     K16073  ALR, MNR; magnesium transporter
     K16074  zntB; zinc transporter
     K16075  MRS2, MFM1; magnesium transporter
     K22188  CLCC1; chloride channel CLIC-like protein 1
     K06466  MS4A1, CD20; B-lymphocyte antigen CD20
     K08090  MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
     K22190  MS4A3S; membrane-spanning 4-domains subfamily A member 3/4/8/12/15/18
     K22191  MS4A5_6_7; membrane-spanning 4-domains subfamily A member 5/6/7
     K22189  MS4A10; membrane-spanning 4-domains subfamily A member 10
     K22192  MS4A14; membrane-spanning 4-domains subfamily A member 14
     K22193  GPR89, GPHR; golgi pH regulator
     K06199  crcB, FEX; fluoride exporter
     K13878  BEST1, VMD2; bestrophin-1
     K13879  BEST2, VMD2L1; bestrophin-2
     K13880  BEST3, VMD2L3; bestrophin-3
     K13881  BEST4, VMD2L2; bestrophin-4
     K22204  BEST; bestrophin, other
     K08994  yneE, BEST; ion channel-forming bestrophin family protein
     K16059  STIM1; stromal interaction molecule 1
     K18196  STIM2; stromal interaction molecule 2
     K16056  ORAI1; calcium release-activated calcium channel protein 1
     K16057  ORAI2; calcium release-activated calcium channel protein 2
     K16058  ORAI3; calcium release-activated calcium channel protein 3
     K21099  MARVELD3; MARVEL domain-containing protein 3
     K08363  merT; mercuric ion transport protein
     K08364  merP; periplasmic mercuric ion binding protein
     K19058  merC; mercuric ion transport protein
     K19059  merE; mercuric ion transport protein
     K22128  PIEZO1_2, FAM38; piezo-type mechanosensitive ion channel component 1/2
     K20858  MCU; calcium uniporter protein, mitochondrial
     K19738  CALHM1; calcium homeostasis modulator protein 1
     K19739  CALHM2; calcium homeostasis modulator protein 2
     K19740  CALHM3; calcium homeostasis modulator protein 3
     K13351  PEX11A; peroxin-11A
     K13352  PEX11B; peroxin-11B
     K13353  PEX11C; peroxin-11C
     K21891  TMCO1; calcium load-activated calcium channel
     K21892  MB; myoglobin
     K21893  NGB; neuroglobin
     K21894  CYGB; cytoglobin
     K09476  ompF; outer membrane pore protein F
     K11929  phoE; outer membrane pore protein E
     K09475  ompC; outer membrane pore protein C
     K16076  nmpC, ompD; outer membrane porin protein LC
     K14062  ompN; outer membrane protein N
     K08720  ompU; outer membrane protein OmpU
     K18132  K18132, porA; major outer membrane protein P.IA
     K18133  K18133, porB; major outer membrane protein P.IB
     K10940  ompT; outer membrane protein OmpT
     K03162  ompA; major outer membrane protein
     K08719  K08719, porB; outer membrane protein B
     K02024  lamB; maltoporin
     K16077  scrY; sucrose porin
     K10124  bglH; carbohydrate-specific outer membrane porin
     K16079  omp31; outer membrane immunogenic protein
     K16080  mnoP; high affinity Mn2+ porin
     K07221  oprO_P; phosphate-selective porin OprO and OprP
     K16191  K16191, arfA; peptidoglycan-binding protein ArfA
     K03286  TC.OOP; OmpA-OmpF porin, OOP family
     K11934  ompX; outer membrane protein X
     K16078  ail; attachment invasion locus protein
     K05862  VDAC1; voltage-dependent anion channel protein 1
     K15040  VDAC2; voltage-dependent anion channel protein 2
     K15041  VDAC3; voltage-dependent anion channel protein 3
     K06076  fadL; long-chain fatty acid transport protein
     K05517  tsx; nucleoside-specific channel-forming protein
     K07347  fimD, fimC, mrkC, htrE, cssD; outer membrane usher protein
     K12678  aidA-I, misL; autotransporter family porin
     K12679  icsA, virG; outer membrane protein IcsA
     K07279  yfaL; autotransporter family porin
     K12681  prn; pertactin
     K12682  tcfA; tracheal colonization factor
     K12683  brkA; serum resistance protein
     K01347  iga; IgA-specific serine endopeptidase [EC:3.4.21.72]
     K12684  esp, sigA, sepA; serine protease autotransporter [EC:3.4.21.-]
     K12685  ssp; subtilase-type serine protease [EC:3.4.21.-]
     K12516  bigA; putative surface-exposed virulence protein
     K11028  vacA; vacuolating cytotoxin
     K12686  apeE, estA, lip-1; outer membrane lipase/esterase
     K12687  flu; antigen 43
     K12688  sphB1, nalP, ausP; autotransporter serine protease [EC:3.4.21.-]
     K12689  capA; campylobacter adhesion protein
     K19231  bmaC; fibronectin-binding autotransporter adhesin
     K16081  algE; alginate production protein
     K19611  fepA, pfeA, iroN, pirA; ferric enterobactin receptor
     K16090  fiu; catecholate siderophore receptor
     K16091  fecA; Fe(3+) dicitrate transport protein
     K16092  btuB; vitamin B12 transporter
     K21573  susC; TonB-dependent starch-binding outer membrane protein SusC
     K12545  hasA; heme acquisition protein HasA
     K16152  hasR; heme acquisition protein HasR
     K15721  fyuA; pesticin/yersiniabactin receptor
     K16088  TC.FEV.OM1, fhuE, fpvA, fptA; outer-membrane receptor for ferric coprogen and ferric-rhodotorulic acid
     K16089  TC.FEV.OM2, cirA, cfrA, hmuR; outer membrane receptor for ferrienterochelin and colicins
     K16087  TC.FEV.OM3, tbpA, hemR, lbpA, hpuB, bhuR, hugA, hmbR; hemoglobin/transferrin/lactoferrin receptor protein
     K02014  TC.FEV.OM; iron complex outermembrane recepter protein
     K12538  hasF, prtF; outer membrane protein, protease secretion system
     K15725  czcC; outer membrane protein, cobalt-zinc-cadmium efflux system
     K07796  cusC, silC; outer membrane protein, Cu(I)/Ag(I) efflux system
     K12340  tolC; outer membrane protein
     K12535  rsaF; outer membrane protein, S-layer protein transport system
     K12543  lapE; outer membrane protein, adhesin transport system
     K18903  oprC, opcM; outer membrane protein, multidrug efflux system
     K08721  oprJ; outer membrane protein, multidrug efflux system
     K18300  oprN; outer membrane protein, multidrug efflux system
     K18308  opmD; outer membrane protein, multidrug efflux system
     K19593  opmE; outer membrane protein, multidrug efflux system
     K18139  oprM, emhC, ttgC, cusC, adeK, smeF, mtrE, cmeC, gesC; outer membrane protein, multidrug efflux system
     K18904  nodT, ameC; outer membrane protein, multidrug efflux system
     K18323  smeC; outer membrane protein, multidrug efflux system
     K18147  adeC; outer membrane protein, multidrug efflux system
     K15550  mdtP; outer membrane protein, multidrug efflux system
     K16552  exoF; polysaccharide biosynthesis/export protein ExoF
     K20987  pslD; polysaccharide biosynthesis/export protein PslD
     K20988  vpsN; polysaccharide biosynthesis/export protein VpsN
     K01991  ABC-2.OM, wza; polysaccharide biosynthesis/export protein
     K07267  oprB; porin
     K14053  ompG; outer membrane protein G
     K18093  oprD; imipenem/basic amino acid-specific outer membrane pore [EC:3.4.21.-]
     K16140  uidC, gusC; putative glucuronide porin
     K16517  galP; porin-like protein GalP
     K21758  benP; benzoate transport porin
     K07277  SAM50, TOB55, bamA; outer membrane protein insertion porin family
     K17713  bamB; outer membrane protein assembly factor BamB
     K07287  bamC; outer membrane protein assembly factor BamC
     K05807  bamD; outer membrane protein assembly factor BamD
     K06186  bamE, smpA; outer membrane protein assembly factor BamE
     K07278  tamA; translocation and assembly module TamA
     K09800  tamB; translocation and assembly module TamB
     K17714  SAM37, TOM37; sorting and assembly machinery component 37
     K17715  SAM35, TOM38; sorting and assembly machinery component 35
     K17774  MDM10; mitochondrial distribution and morphology protein 10
     K22110  kdgM, kdgN, nanC, ompL; oligogalacturonate-specific porin family protein
     K21449  ata, sadA, emaA; trimeric autotransporter adhesin
     K19232  btaE; hyaluronate-binding autotransporter adhesin
     K19233  btaF; ECM component-binding autotransporter adhesin
     K09774  lptA; lipopolysaccharide export system protein LptA
     K06861  lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-]
     K11719  lptC; lipopolysaccharide export system protein LptC
     K04744  lptD, imp, ostA; LPS-assembly protein
     K03643  lptE, rlpB; LPS-assembly lipoprotein
     K20543  bcsC; cellulose synthase operon protein C
     K20920  vpsM; polysaccharide biosynthesis protein VpsM
     K11720  lptG; lipopolysaccharide export system permease protein
     K11005  hlyA; hemolysin A
     K10948  hlyA; hemolysin
     K11032  hlyII; hemolysin II
     K11038  hlg, luk; leukocidin/hemolysin toxin family protein
     K20482  nisA, spaS, epiA; lantibiotic bacteriocin
     K13285  sipB, ipaB, bipB; invasin B
     K13287  sipD, ipaD, bipD; invasin D
     K15344  sseB; secreted effector protein SseB
     K15345  sseC; secreted effector protein SseC
     K15346  sseD; secreted effector protein SseD
     K18977  HPX; hemopexin
     K12377  TSL; torso-like protein
     K05399  LBP; lipopolysaccharide-binding protein
     K16835  CETP; cholesteryl ester transfer protein
     K08761  PLTP; phospholipid transfer protein
     K20668  DEF; defensin
     K16626  ha-70; hemagglutinin components HA-22/23/53
     K11023  ptxA, artA; pertussis toxin subunit 1 [EC:2.4.2.-]
     K11024  ptxB; pertussis toxin subunit 2
     K11025  ptxC; pertussis toxin subunit 3
     K11026  ptxD; pertussis toxin subunit 4
     K11027  ptxE; pertussis toxin subunit 5
     K19297  subA; subtilase cytotoxin, subunit A
     K19298  subB, artB; subtilase cytotoxin, subunit B
     K21100  DEFB4; beta-defensin 4
     K18832  PENK; proenkephalin A
     K15840  PDYN, PENKB; proenkephalin B (prodynorphin)
     K20669  DPT; diptericin
     K22141  GSDMA; gasdermin-A
     K22142  GSDMB; gasdermin-B
     K22143  GSDMC; gasdermin-C
     K20917  GSDMD; gasdermin-D
     K05338  lrgA; holin-like protein
     K06518  cidA; holin-like protein
   Electrochemical potential-driven transporters [TC:2]
   Primary active transporters [TC:3]
   Transmembrane electron carriers [TC:5]
   Accessory factors involved in transport [TC:8]
   Others

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Last updated: December 4, 2017
ABC classifications based on Igarashi et al. (2004) and Tomii & Kanehisa (1998)
MFS classification taken from TCDB