Transcription Factors

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1st Level  2nd Level  3rd Level  4th Level 

 Eukaryotic Type
   Basic leucine zipper (bZIP)
   Basic helix-loop-helix (bHLH)
   Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Other basic domains
   Zinc finger
     Cys4 thyroid hormone-like
     Cys4 hepatocyte nuclear factor 4-like
       K07292  NR2A1, HNF4A; hepatocyte nuclear factor 4-alpha
       K08037  NR2A2, HNF4G; hepatocyte nuclear factor 4-gamma
       K08542  NR2A3, HNF4B; hepatocyte nuclear factor 4-beta
       K08704  NR2A4, Hnf4; hepatocyte nuclear factor 4
       K07295  NR2AN, dsf; nuclear receptor subfamily 2 group A
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K08525  RXRB, NR2B2; retinoid X receptor beta
       K08526  RXRG, NR2B3; retinoid X receptor gamma
       K14030  NR2B4, usp; nuclear receptor subfamily 2 group B member 4
       K08543  NR2C1, TR2; testicular receptor 2
       K08544  NR2C2, TR4; testicular receptor 4
       K14031  NR2CN; nuclear receptor subfamily 2 group C
       K08545  NR2E1, TLX, tll; nuclear receptor subfamily 2 group E member 1
       K08546  NR2E3, PNR; nuclear receptor subfamily 2 group E member 3
       K08547  NR2F1, TFCOUP1; COUP transcription factor 1
       K08548  NR2F2, TFCOUP2; COUP transcription factor 2
       K14032  NR2F3, svp; nuclear receptor subfamily 2 group F member 3
       K08702  NR2F5, SVP46; nuclear receptor subfamily 2 group F member 5
       K08549  NR2F6, EAR2; nuclear receptor subfamily 2 group F member 6
     Cys4 estrogen-like
     Cys4 nerve growth factor IB-like
     Cys4 Fushi tarazu-F1-like
     Cys4 germ cell nuclear factor
     Cys4 Knirps/DAX 1-like
     Cys4 GATA-factors
     Cys4 Trithorax
     Other Cys4 zinc finger factors
     Cys2His2 ubiquitous factors
     Cys2His2 developmental/cell cycle regulators, Egr/Krox
     Cys2His2 developmental/cell cycle regulators, Krueppel-like
     Cys2His2 developmental/cell cycle regulators, GLI-like
     Cys2His2 developmental/cell cycle regulators, Others
     Cys2His2 metabolic regulators in fungi
     Cys2His2 large factors with NF-6B-like binding properties
     Other Cys2His2 zinc factors
     Cys6 metabolic regulators in fungi
     Cys4HisCys3 PHD fingers
     Zinc fingers of alternating composition
   beta-Scaffold factors with minor groove contacts
   Other transcription factors
 Prokaryotic Type

Last updated: March 23, 2018
Classification taken and modified from TRANSFAC 7.0