Transcription Factors

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1st Level  2nd Level  3rd Level  4th Level 

 Eukaryotic Type
   Basic leucine zipper (bZIP)
   Basic helix-loop-helix (bHLH)
   Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Other basic domains
   Zinc finger
     Cys4 thyroid hormone-like
       K05547  NR1A1, THRA; thyroid hormone receptor alpha
       K08362  NR1A2, THRB; thyroid hormone receptor beta
       K08527  NR1B1, RARA; retinoic acid receptor alpha
       K08528  NR1B2, RARB; retinoic acid receptor beta
       K08529  NR1B3, RARG; retinoic acid receptor gamma
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K03728  NR1D1; nuclear receptor subfamily 1 group D member 1
       K08531  NR1D2; nuclear receptor subfamily 1 group D member 2
       K08701  NR1D3; nuclear receptor subfamily 1 group D member 3
       K08532  NR1F1, RORA; RAR-related orphan receptor alpha
       K08533  NR1F2, RORB; RAR-related orphan receptor beta
       K08534  NR1F3, RORC; RAR-related orphan receptor gamma
       K14033  NR1F4; nuclear receptor subfamily 1 group F member 4
       K08536  NR1H3, LXRA; liver X receptor alpha
       K08535  NR1H2, LXRB; liver X receptor beta
       K08537  NR1H4, FXR; farnesoid X receptor
       K08538  NR1H5, FXRB; farnesoid X receptor beta
       K14034  NR1H1, EcR; ecdysone receptor
       K08539  NR1I1, VDR; vitamin D3 receptor
       K08540  NR1I2, PXR; pregnane X receptor
       K08541  NR1I3, CAR; constitutive androstane receptor
       K14035  NR1IN; nuclear receptor subfamily 1 group I
     Cys4 hepatocyte nuclear factor 4-like
     Cys4 estrogen-like
     Cys4 nerve growth factor IB-like
     Cys4 Fushi tarazu-F1-like
     Cys4 germ cell nuclear factor
     Cys4 Knirps/DAX 1-like
     Cys4 GATA-factors
     Cys4 Trithorax
     Other Cys4 zinc finger factors
     Cys2His2 ubiquitous factors
     Cys2His2 developmental/cell cycle regulators, Egr/Krox
     Cys2His2 developmental/cell cycle regulators, Krueppel-like
     Cys2His2 developmental/cell cycle regulators, GLI-like
     Cys2His2 developmental/cell cycle regulators, Others
     Cys2His2 metabolic regulators in fungi
     Cys2His2 large factors with NF-6B-like binding properties
     Cys6 metabolic regulators in fungi
     Cys4HisCys3 PHD fingers
     Zinc fingers of alternating composition
   beta-Scaffold factors with minor groove contacts
   Other transcription factors
 Prokaryotic Type

Last updated: July 28, 2015
Classification taken and modified from TRANSFAC 7.0