Messenger RNA Biogenesis

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 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
       EJC complex
       TREX complex
       TREX-2 complex
       Nuclear pore complex
         K09291  TPR, MLP1, MLP2; nucleoprotein TPR
         K14298  RAE1, GLE2; mRNA export factor
         K14004  SEC13; protein transport protein SEC13
         K14302  NUP37; nuclear pore complex protein Nup37
         K14304  NUP85; nuclear pore complex protein Nup85
         K14305  NUP43; nuclear pore complex protein Nup43
         K14295  NUP50, NPAP60; nuclear pore complex protein Nup50
         K14308  NUP54, NUP57; nuclear pore complex protein Nup54
         K14306  NUP62, NSP1; nuclear pore complex protein Nup62
         K14318  NUP88; nuclear pore complex protein Nup88
         K14309  NUP93, NIC96; nuclear pore complex protein Nup93
         K14297  NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
         K14301  NUP107, NUP84; nuclear pore complex protein Nup107
         K14300  NUP133; nuclear pore complex protein Nup133
         K14311  NUP188; nuclear pore complex protein Nup188
         K14296  NUP153; nuclear pore complex protein Nup153
         K14312  NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
         K14303  NUP160, NUP120; nuclear pore complex protein Nup160
         K14313  NUP35, NUP53; nuclear pore complex protein Nup53
         K14310  NUP205, NUP192; nuclear pore complex protein Nup205
         K14314  NUP210, GP210; nuclear pore complex protein Nup210
         K14317  NUP214, CAN; nuclear pore complex protein Nup214
         K14316  POM121, NUP121; nuclear pore complex protein Nup121
         K14307  NUPL1, NUP49; nucleoporin p58/p45
         K14321  NUPL2, NUP42, CG1; nucleoporin-like protein 2
         K14315  NDC1, TMEM48; nucleoporin NDC1
         K14299  SEH1; nucleoporin SEH1
         K12172  RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
         K03345  SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
         K14320  AAAS; aladin
         K18715  NUP159; nucleoporin NUP159
         K18716  NUP42, RIP1; nucleoporin NUP42
         K18717  ASM4, NUP59; nucleoporin ASM4
         K18718  NUP60; nucleoporin NUP60
         K18719  NUP82; nucleoporin NUP82
         K18720  NUP145; nucleoporin NUP145
         K18721  NUP1; nucleoporin NUP1
         K18722  NUP2; nucleoporin NUP2
         K16466  CETN3, CDC31; centrin-3
         K18723  GLE1; nucleoporin GLE1
         K14284  NXF, TAP, MEX67; nuclear RNA export factor
         K14285  NXT1_2, P15; NTF2-related export protein 1/2
         K26564  NPAP1; nuclear pore-associated protein 1
         K14543  MTR2; mRNA transport regulator MTR2
         K18724  POM34; nucleoporin POM34
         K18725  POM152; nucleoporin POM152
         K14017  SNL1; HSP70 co-chaperone SNL1
       Ran-mediated transport factors
       eIF4F and regulatory proteins
       APOBEC1-ACF complex
       Other transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
       P-body specific factors
       Stress granule specific factors
         K13201  TIA1, TIAL1; nucleolysin TIA-1/TIAR
         K13126  PABPC; polyadenylate-binding protein
         K17597  STAU; double-stranded RNA-binding protein Staufen
         K15516  FMR; fragile X mental retardation protein
         K12965  ZBP1, DAI; Z-DNA binding protein 1
         K13088  ELAVL1, HUR; ELAV-like protein 1
         K17265  G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.3 3.6.4.13]
         K24983  G3BP2; Ras GTPase-activating protein-binding protein 2
         K15026  EIF2A; translation initiation factor 2A
         K03253  EIF3B; translation initiation factor 3 subunit B
         K03257  EIF4A; translation initiation factor 4A
         K13025  EIF4A3, FAL1; ATP-dependent RNA helicase [EC:3.6.4.13]
         K03258  EIF4B; translation initiation factor 4B
         K03260  EIF4G; translation initiation factor 4G
         K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
         K14753  RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
         K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
         K14284  NXF, TAP, MEX67; nuclear RNA export factor
         K11407  HDAC6; histone deacetylase 6 [EC:3.5.1.98]
         K18404  TDRD3; tudor domain-containing protein 3
         K18763  LARP4; la-related protein 4
   mRNA degradation factors
 
 Prokaryotic type

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Last updated: April 9, 2024