DNA Repair and Recombination Proteins

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 Eukaryotic Type
 
 Prokaryotic Type
   SSBR (single strand breaks repair)
     Direct repair
     BER (base exicision repair)
       DNA glycosylases
       AP endonucleases
       RecJ
       DNA ligase
         K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
         K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       DNA polymerase I
     NER (nucleotide excision repair)
       GGR (global genome repair) factors
         K03701  uvrA; excinuclease ABC subunit A
         K03702  uvrB; excinuclease ABC subunit B
         K03703  uvrC; excinuclease ABC subunit C
         K05984  cho; excinuclease Cho [EC:3.1.25.-]
         K03657  uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
         K02335  DPO1, polA; DNA polymerase I [EC:2.7.7.7]
         K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
         K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       TCR (transcription coupled repair) factors
     MMR (mismatch exicision repair)
       Mismatch and loop recognition factors
       Molecular matchmaker
       Strand discrimination factor
       DNA exonucleases
       DNA polymerase III holoenzyme
       DNA ligase
         K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
         K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]
       Other MMR factors
   DSBR (double strand breaks repair)
     HR (homologous recombination)
     NHEJ (non-homologous end-joining)
       Two-component NHEJ DNA repair complex
         K10979  ku; DNA end-binding protein Ku
         K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
       SHIIR (short-homology-independent illegitimate recombination)
       SHDIR (short-homology-dependent illegitimate recombination)
         RecET pathway
           K10906  recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
           K07455  recT; recombination protein RecT
           K07462  recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
           K03584  recO; DNA repair protein RecO (recombination protein O)
           K06187  recR; recombination protein RecR
           K01971  E6.5.1.1, lig; DNA ligase (ATP) [EC:6.5.1.1]
         Facilitator
         Supressor
   TLS (translesion DNA synthesis) factors
   Other factors with a suspected DNA repair function

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Last updated: June 11, 2014