DNA Repair and Recombination Proteins

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 Eukaryotic Type
   SSBR (single strand breaks repair)
     Direct repair
     BER (base exicision repair)
       DNA glycosylases
       AP endonucleases
       Long Patch-BER factors
         DNA polymerase delta complex
         DNA polymerase epsilon complex
         K04802  PCNA; proliferating cell nuclear antigen
         K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.-.-.-]
         K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
       Short Patch-BER factors
       Other BER factors
     NER (nucleotide excision repair)
       GGR (global genome repair) factors
       TCR (transcription coupled repair) factors
       TFIIH complex
       RPA (replication factor A)
       Other NER factors
         K10847  XPA; DNA-repair protein complementing XP-A cells
         K10849  ERCC1; DNA excision repair protein ERCC-1
         K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
         K10846  ERCC5, XPG, RAD2; DNA excision repair protein ERCC-5
         K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
         K15075  MET18, MMS19; DNA repair/transcription protein MET18/MMS19
         K03869  CUL3; cullin 3
         K10612  CUL5; cullin 5
         K03872  TCEB1; transcription elongation factor B, polypeptide 1
         K03873  TCEB2; transcription elongation factor B, polypeptide 2
         K15076  TCEB3, ELOA; transcription elongation factor B, polypeptide 3
         K15077  ELA1; elongin-A
     MMR (mismatch exicision repair)
       Mismatch and loop recognition factors
       MutS homologs specialized for meiosis
       MutL homologs
       DNA polymerase delta complex
       RPA (replication factor A)
       RFC (replication factor C)
       Other MMR factors
         K04802  PCNA; proliferating cell nuclear antigen
         K10746  EXO1; exonuclease 1 [EC:3.1.-.-]
         K10802  HMGB1; high mobility group protein B1
         K10747  LIG1; DNA ligase 1 [EC:6.5.1.1]
   DSBR (double strand breaks repair)
   TLS (translesion DNA synthesis) factors
   Check point factors
   Other factors with a suspected DNA repair function
 
 Prokaryotic Type

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Last updated: June 11, 2014