Ubiquitin System

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 Ubiquitins and Ubiquitin-like proteins
 Ubiquitin-activating enzymes (E1)
 Ubiquitin-conjugating enzymes (E2)
 Ubiquitin ligases (E3)
   HECT type E3
   U-box type E3
   Single Ring-finger type E3
     BRE1 proteins
     CBL proteins
     SINA (Seven in absentia) proteins
     Ligand of Numb proteins
     March proteins
     MDM2/MDM4 proteins
     NFX1 proteins
     Pellino proteins
     Peripheral membrane proteins
     RBR proteins
     TRAF proteins
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:]
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:]
       K10646  TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7 [EC:]
     TRIM/RBCC proteins
     UBR box proteins
     ATL proteins
     Other single Ring-finger type E3
   UBL E3 ligases
   Multi subunit Ring-finger type E3
 Deubiquitinating enzyme (DUB)

Last updated: October 1, 2015