Cell Adhesion Molecules and Their Ligands

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     Ligand type
 1. Immunoglobulin Superfamily
 
 2. Integrin Family
   Beta1 integrins
     VLA-1
     VLA-2
     VLA-3
       ITGA3; integrin alpha 3 [KO:K06482]
       ITGB1; integrin beta 1 [KO:K05719]
         VLA-2
Cell adhesion molecules (CAMs)
         VLA-3
Cell adhesion molecules (CAMs)
         K06237 COL4A; collagen, type IV, alpha
Extracellular matrix (ECM) components
         Laminin-2
Extracellular matrix (ECM) components
         Laminin-5
Extracellular matrix (ECM) components
         Laminin-10
Extracellular matrix (ECM) components
         Laminin-11
Extracellular matrix (ECM) components
         K16857 THBS1; thrombospondin 1
Extracellular matrix (ECM) components
         K04659 THBS2S; thrombospondin 2/3/4/5
Extracellular matrix (ECM) components
         K06249 RELN; reelin [EC:3.4.21.-]
Extracellular matrix (ECM) components
         K06826 NID; nidogen (entactin)
Extracellular matrix (ECM) components
         K06831 LGALS3; galectin-3
Other cell surface / pericellular molecules
         K06832 LGALS8; galectin-8
Other cell surface / pericellular molecules
         enterotoxin type A, putative [SAC:SACOL1657]
Bacterial pathogens
         seb; staphylococcal enterotoxin B [SAC:SACOL0907]
Bacterial pathogens
         K11043 tst; toxic shock syndrome toxin-1
Bacterial pathogens
         sec3; enterotoxin typeC3 [SAV:SAV2009]
Bacterial pathogens
         speA3; exotoxin type A - phage associated [SPG:SpyM3_1301]
Bacterial pathogens
         putative invasin [YPS:YPTB1572]
Bacterial pathogens
         putative invasin [YPS:YPTB1668]
Bacterial pathogens
         Human herpesvirus 8 [VGNM:NC_009333], gB
Viruses
     VLA-4
     VLA-5
     VLA-6
     VLA-7
     VLA-8
     VLA-9
     alpha 10 beta 1
     alpha 11 beta 1
     alpha V beta 1
   Beta2 integrins
   Beta3 integrins
     alpha IIb  beta 3
       ITGA2B; integrin alpha 2B [KO:K06476]
       ITGB3; integrin beta 3 [KO:K06493]
         K06581 ICAM4; intercellular adhesion molecule 4
         K06798 CDH6; cadherin 6, type 2, K-cadherin
         K03161 TNFSF5, CD40L; tumor necrosis factor ligand superfamily member 5
         K06251 VTN; vitronectin
         K05717 FN1; fibronectin 1
         K03900 VWF; von Willebrand factor
         K04659 THBS2S; thrombospondin 2/3/4/5
         K03903 FGA; fibrinogen alpha chain
         K03904 FGB; fibrinogen beta chain
         K03905 FGG; fibrinogen gamma chain
         K06829 CYR61; cysteine rich protein 61
         K06827 CTGF; connective tissue growth factor
         K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
         speB; pyrogenic exotoxin B [EC:3.4.22.10] [SPG:SpyM3_1742]
         membrane-associated protein P66 [BBU:BB0603]
         Sin Nombre virus [VGNM:NC_005215], G1, G2
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Bacterial pathogens
Bacterial pathogens
Viruses
     VNR
       ITGAV; integrin alpha V [KO:K06487]
       ITGB3; integrin beta 3 [KO:K06493]
         K06550 L1CAM; L1 cell adhesion molecule
         K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
         K06581 ICAM4; intercellular adhesion molecule 4
         K06257 SDC1; syndecan 1
         K06514 THY1, CD90; Thy-1 cell surface antigen
         K06251 VTN; vitronectin
         K05717 FN1; fibronectin 1
         K03900 VWF; von Willebrand factor
         K06825 FBN1; fibrillin 1
         K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
         K06252 TN; tenascin
         K06253 IBSP; integrin binding sialoprotein
         K04659 THBS2S; thrombospondin 2/3/4/5
         K06236 COL1AS; collagen, type I/II/III/V/XI/XXIV/XXVII, alpha
         K06237 COL4A; collagen, type IV, alpha
         K06823 COL18A; collagen, type XVIII, alpha
         K03903 FGA; fibrinogen alpha chain
         K03904 FGB; fibrinogen beta chain
         K03905 FGG; fibrinogen gamma chain
         K06829 CYR61; cysteine rich protein 61
         K06827 CTGF; connective tissue growth factor
         K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
         K01315 PLG; plasminogen [EC:3.4.21.7]
         K06836 ADAM15; disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-]
         K06837 ADAM23; disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-]
         speB; pyrogenic exotoxin B [EC:3.4.22.10] [SPG:SpyM3_1742]
         membrane-associated protein P66 [BBU:BB0603]
         Human adenovirus type 2, penton base protein
         Human herpesvirus 1 [VGNM:NC_001806], gH
         Human coxsackievirus A9 (strain Griggs), VP1
         Human coxsackievirus A9B, VP1
         Foot-and-mouth disease virus A, VP1
         Foot-and-mouth disease virus Asia 1, VP1
         Foot-and-mouth disease virus C, VP1
         Foot-and-mouth disease virus O [VGNM:NC_004004], VP1
         Foot-and-mouth disease virus SAT 1, VP1
         Foot-and-mouth disease virus SAT 2, VP1
         Foot-and-mouth disease virus SAT 3, VP1
         Human adenovirus type 5, penton base protein
         Human immunodeficiency virus 1 [VGNM:NC_001802], gp120, 41
         Sin Nombre virus [VGNM:NC_005215], G1, G2
         Echovirus 9 (strain Barty), VP1
         Echovirus 22 (strain Harris), VP1
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Cell adhesion molecules (CAMs)
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Extracellular matrix (ECM) components
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Soluble ligands
Other cell surface / pericellular molecules
Other cell surface / pericellular molecules
Bacterial pathogens
Bacterial pathogens
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
Viruses
   Beta4 integrins
   Beta5 integrins
   Beta6 integrins
   Beta7 integrins
   Beta8 integrins
 
 3. Selectin Family
 
 4. Link Protein Family
 
 5. Cadherin Family
 
 6. Sialomucin Family
 
 7. Others
   TNFRSF5, CD40; tumor necrosis factor receptor superfamily, member 5 [KO:K03160]
   TNFSF5, CD40L; tumor necrosis factor (ligand) superfamily, member 5 [KO:K03161]
   NRP1; neuropilin 1 [KO:K06724]
   NRP2; neuropilin 2 [KO:K06819]
   PLXNA; plexin A [KO:K06820]
   PLXNB; plexin B [KO:K06821]
   PLXNC; plexin C [KO:K06572]
   PLXND; plexin D [KO:K06822]
   SDC1; syndecan 1 [KO:K06257]
   SDC2; syndecan 2 [KO:K16336]
   SDC3; syndecan 3 [KO:K16337]
   SDC4; syndecan 4 [KO:K16338]
     K06514 THY1, CD90; Thy-1 cell surface antigen
Cell adhesion molecules (CAMs)
     VLA-5
Cell adhesion molecules (CAMs)
     alpha 6 beta 4
Cell adhesion molecules (CAMs)
     K04659 THBS2S; thrombospondin 2/3/4/5
Extracellular matrix (ECM) components
     K05717 FN1; fibronectin 1
Extracellular matrix (ECM) components
     K06252 TN; tenascin
Extracellular matrix (ECM) components
     K18496 FGF1; fibroblast growth factor 1
Soluble ligands
     K18497 FGF2; fibroblast growth factor 2
Soluble ligands
     K04358 FGF; fibroblast growth factor
Soluble ligands
     K06732 CDCP1; CUB domain-containing protein 1
Other cell surface / pericellular molecules
   CLDN; claudin [KO:K06087]
   OCLN; occludin [KO:K06088]
   CD99, MIC2; CD99 antigen [KO:K06520]
   NRXN; neurexin [KO:K07377]
   NLGN; neuroligin [KO:K07378]
   DAG1; dystroglycan 1 [KO:K06265]
   LRRTM1_2; leucine-rich repeat transmembrane neuronal protein 1/2 [KO:K16665]
   OMG; oligodendrocyte myelin glycoprotein [KO:K16666]
   APP; amyloid beta A4 protein [KO:K04520]
   PTPRG; receptor-type tyrosine-protein phosphatase gamma [KO:K16667]
   NTNG1; netrin-G1 [KO:K07522]
   NTNG2; netrin-G2 [KO:K16359]
   FLRT; leucine-rich repeat transmembrane protein FLRT [KO:K16362]
   CD209; CD209 antigen [KO:K06563]
   CD81, TAPA1; CD81 antigen [KO:K06508]
   SCARB1; scavenger receptor class B, member 1 [KO:K13885]
   TMIGD2, IGPR-1; transmembrane and immunoglobulin domain-containing protein 2 [KO:K16668]
   EFNA; ephrin-A [KO:K05462]
   EPHA1, EPH; Eph receptor A1 [KO:K05102]
   EPHA2, ECK; Eph receptor A2 [KO:K05103]
   EPHA3, HEK, TYRO4; Eph receptor A3 [KO:K05104]
   EPHA4, SEK, TYRO1; Eph receptor A4 [KO:K05105]
   EPHA5, EHK1, TYRO4; Eph receptor A5 [KO:K05106]
   EPHA6, EHK2; Eph receptor A6 [KO:K05107]
   EPHA7, EHK3, HEK11; EphA7 [KO:K05108]
   EPHA8, EEK; Eph receptor A8 [KO:K05109]
   EPHA10; Eph receptor A10 [KO:K08897]
   EFNB; ephrin-B [KO:K05463]
   EPHB1, ELK, NET; Eph receptor B1 [KO:K05110]
   EPHB2, ERK, DRT; Eph receptor B2 [KO:K05111]
   EPHB3; EPHB3, HEK2, ETK2; Eph receptor B3 [KO:K05112]
   EPHB4; EPHB4, HTK; Eph receptor B4 [KO:K05113]
   EPHB6; Eph receptor B6 [KO:K05114]

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Last updated: August 29, 2014