Cell Adhesion Molecules and Their Ligands

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     Ligand type
 1. Immunoglobulin Superfamily
   Immune system
   Neural system
   Others
     VCAM1; vascular cell adhesion molecule 1 [KO:K06527]
     PECAM1, CD31; platelet/endothelial cell adhesion molecule [KO:K06471]
     MADCAM1; mucosal vascular addressin cell adhesion molecule 1 [KO:K06779]
     PVRL1; poliovirus receptor-related 1 [KO:K06081]
     PVRL2; poliovirus receptor-related 2 [KO:K06531]
     PVRL3; poliovirus receptor-related 3 [KO:K06592]
     PVRL4; poliovirus receptor-related 4 [KO:K06593]
     CADM3, IGSF4B, NECL1, TSLL1; cell adhesion molecule 3 [KO:K06780]
     CADM1, IGSF4, NECL2, TSLC1; cell adhesion molecule 1 [KO:K06781]
     CADM2, IGSF4D, NECL3; cell adhesion molecule 2 [KO:K06782]
     CADM4, IGSF4C, TSLL2; cell adhesion molecule 4 [KO:K06783]
     PVR, NECL5; poliovirus receptor [KO:K06539]
     ICAM4; intercellular adhesion molecule 4 [KO:K06581]
     CEACAM; carcinoembryonic antigen-related cell adhesion molecule [KO:K06499]
     ROBO4; roundabout, axon guidance receptor, homolog 4 (Drosophila) [KO:K06784]
     LU; Lutheran blood group glycoprotein [KO:K06578]
       VLA-4
Cell adhesion molecules (CAMs)
       Laminin-10
Extracellular matrix (ECM) components
       Laminin-11
Extracellular matrix (ECM) components
         ------ LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]
         K06243 LAMB2; laminin, beta 2
         K05635 LAMC1; laminin, gamma 1
 
 
 
       Laminin-14
Extracellular matrix (ECM) components
         K06241 LAMA4; laminin, alpha 4
         K06243 LAMB2; laminin, beta 2
         K06247 LAMC3; laminin, gamma 3
 
 
 
     MCAM, CD146; melanoma cell adhesion molecule [KO:K06534]
     F11R, JAM1; junctional adhesion molecule 1 [KO:K06089]
     JAM2; junctional adhesion molecule 2 [KO:K06735]
     JAM3; junctional adhesional molecule 3 [KO:K06785]
     JAM4, JCAM; junctional adhesion molecule 4 [KO:K06786]
     ESAM; endothelial cell adhesion molecule [KO:K06787]
     CXADR, CAR; coxsackievirus and adenovirus receptor [KO:K06788]
     ASAM, CLMP; adipocyte-specific adhesion molecule [KO:K06789]
     GPA33; glycoprotein A33 (transmembrane) [KO:K06790]
     IGSF11; immunoglobulin superfamily, member 11 [KO:K06791]
     CRTAM; cytotoxic and regulatory T-cell molecule [KO:K16361]
     UNC5; netrin receptor unc-5 [KO:K07521]
 
 2. Integrin Family
   Beta1 integrins
     VLA-1
     VLA-2
     VLA-3
       ITGA3; integrin alpha 3 [KO:K06482]
       ITGB1; integrin beta 1 [KO:K05719]
         VLA-2
Cell adhesion molecules (CAMs)
         VLA-3
Cell adhesion molecules (CAMs)
         K06237 COL4A; collagen, type IV, alpha
Extracellular matrix (ECM) components
         Laminin-2
Extracellular matrix (ECM) components
         Laminin-5
Extracellular matrix (ECM) components
         Laminin-10
Extracellular matrix (ECM) components
         Laminin-11
Extracellular matrix (ECM) components
           ------ LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]
           K06243 LAMB2; laminin, beta 2
           K05635 LAMC1; laminin, gamma 1
 
 
 
         K16857  THBS1; thrombospondin 1
Extracellular matrix (ECM) components
         K04659  THBS2S; thrombospondin 2/3/4/5
Extracellular matrix (ECM) components
         K06249 RELN; reelin [EC:3.4.21.-]
Extracellular matrix (ECM) components
         K06826 NID; nidogen (entactin)
Extracellular matrix (ECM) components
         K06831 LGALS3; galectin-3
Other cell surface / pericellular molecules
         K06832 LGALS8; galectin-8
Other cell surface / pericellular molecules
         enterotoxin type A, putative [SAC:SACOL1657]
Bacterial pathogens
         seb; staphylococcal enterotoxin B [SAC:SACOL0907]
Bacterial pathogens
         K11043 tst; toxic shock syndrome toxin-1
Bacterial pathogens
         sec3; enterotoxin typeC3 [SAV:SAV2009]
Bacterial pathogens
         speA3; exotoxin type A - phage associated [SPG:SpyM3_1301]
Bacterial pathogens
         putative invasin  [YPS:YPTB1572]
Bacterial pathogens
         putative invasin [YPS:YPTB1668]
Bacterial pathogens
         Human herpesvirus 8 [TAX:37296] [RS:NC_00340], gB
Viruses
     VLA-4
     VLA-5
     VLA-6
       ITGA6; integrin alpha 6 [KO:K06485]
       ITGB1; integrin beta 1 [KO:K05719]
         Laminin-1
Extracellular matrix (ECM) components
         Laminin-2
Extracellular matrix (ECM) components
         Laminin-5
Extracellular matrix (ECM) components
         Laminin-8
Extracellular matrix (ECM) components
         Laminin-10
Extracellular matrix (ECM) components
         Laminin-11
Extracellular matrix (ECM) components
           ------ LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]
           K06243 LAMB2; laminin, beta 2
           K05635 LAMC1; laminin, gamma 1
 
 
 
         K06827 CTGF; connective tissue growth factor
Soluble ligands
         K06829 CYR61; cysteine rich protein 61
Soluble ligands
         K06828 MDK; midkine
Soluble ligands
         K06833 ADAM2; disintegrin and metalloproteinase domain-containing protein 2 [EC:3.4.24.-]
Other cell surface / pericellular molecules
         K06834 ADAM9; disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-]
Other cell surface / pericellular molecules
         enterotoxin type A, putative [SAC:SACOL1657]
Bacterial pathogens
         seb; staphylococcal enterotoxin B [SAC:SACOL0907]
Bacterial pathogens
         K11043 tst; toxic shock syndrome toxin-1
Bacterial pathogens
         sec3; enterotoxin typeC3 [SAV:SAV2009]
Bacterial pathogens
         speA3; exotoxin type A - phage associated [SPG:SpyM3_1301]
Bacterial pathogens
         putative invasin  [YPS:YPTB1572]
Bacterial pathogens
         putative invasin [YPS:YPTB1668]
Bacterial pathogens
         Human papillomavirus type 16 [TAX:10581] [RS:NC_001526], L1
Viruses
     VLA-7
     VLA-8
     VLA-9
     alpha 10 beta 1
     alpha 11 beta 1
     alpha V beta 1
   Beta2 integrins
   Beta3 integrins
   Beta4 integrins
   Beta5 integrins
   Beta6 integrins
   Beta7 integrins
   Beta8 integrins
 
 3. Selectin Family
 
 4. Link Protein Family
 
 5. Cadherin Family
 
 6. Sialomucin Family
 
 7. Others

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Last updated: April 2, 2014