Eukaryotic type

   Sister chromatid cohesion proteins

   Meiosis-specific proteins

   Nucleosome assembly factors

   Histone modification proteins

   Chromosome condensation proteins

   Centromeric chromatin formation proteins

   Heterochromatin formation proteins

   Gene silencing

   Centrosome formation proteins

   Sister chromatid separation proteins

     Securin and associated proteins

     Separase

     APC/C complex

     Aurora kinases

       Regulators of Aurora kinases

     TACC proteins

     Polo kinases

     Early mitotic inhibitors

   Chromatin remodeling factors

 Prokaryotic type