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KO |
1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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3.1 Acting on ester bonds
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3.2 Glycosylases
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3.3 Acting on ether bonds
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3.4 Acting on peptide bonds (peptidases)
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3.4.11 Aminopeptidases
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3.4.13 Dipeptidases
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3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases
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3.4.15 Peptidyl-dipeptidases
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3.4.16 Serine-type carboxypeptidases
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3.4.17 Metallocarboxypeptidases
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3.4.18 Cysteine-type carboxypeptidases
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3.4.19 Omega peptidases
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3.4.19.1 acylaminoacyl-peptidase
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3.4.19.2 peptidyl-glycinamidase
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3.4.19.3 pyroglutamyl-peptidase I
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3.4.19.5 beta-aspartyl-peptidase
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3.4.19.6 pyroglutamyl-peptidase II
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3.4.19.7 N-formylmethionyl-peptidase
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3.4.19.9 folate gamma-glutamyl hydrolase
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3.4.19.11 gamma-D-glutamyl-meso-diaminopimelate peptidase
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3.4.19.12 ubiquitinyl hydrolase 1
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235461 Mindy2; MINDY lysine 48 deubiquitinase 2
75007 Mindy1; MINDY lysine 48 deubiquitinase 1
50933 Uchl3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
93841 Uchl4; ubiquitin carboxyl-terminal esterase L4
56207 Uchl5; ubiquitin carboxyl-terminal esterase L5
22223 Uchl1; ubiquitin carboxy-terminal hydrolase L1
104416 Bap1; Brca1 associated protein 1
74256 Cyld; CYLD lysine 63 deubiquitinase
107260 Otub1; OTU domain, ubiquitin aldehyde binding 1
68149 Otub2; OTU domain, ubiquitin aldehyde binding 2
216825 Usp22; ubiquitin specific peptidase 22
635253 Usp51; ubiquitin specific protease 51
54651 Usp27x; ubiquitin specific peptidase 27, X chromosome
230484 Usp1; ubiquitin specific peptidase 1
53376 Usp2; ubiquitin specific peptidase 2
224836 Usp49; ubiquitin specific peptidase 49
327799 Usp44; ubiquitin specific peptidase 44
236733 Usp11; ubiquitin specific peptidase 11
22258 Usp4; ubiquitin specific peptidase 4 (proto-oncogene)
72607 Usp13; ubiquitin specific peptidase 13 (isopeptidase T-3)
22225 Usp5; ubiquitin specific peptidase 5 (isopeptidase T)
237898 Usp32; ubiquitin specific peptidase 32
252870 Usp7; ubiquitin specific peptidase 7
84092 Usp8; ubiquitin specific peptidase 8
329908 Usp24; ubiquitin specific peptidase 24
107868 Usp9y; ubiquitin specific peptidase 9, Y chromosome
22284 Usp9x; ubiquitin specific peptidase 9, X chromosome
22224 Usp10; ubiquitin specific peptidase 10
69727 Usp46; ubiquitin specific peptidase 46
22217 Usp12; ubiquitin specific peptidase 12
59025 Usp14; ubiquitin specific peptidase 14
77593 Usp45; ubiquitin specific petidase 45
74112 Usp16; ubiquitin specific peptidase 16
13531 Usp17la; ubiquitin specific peptidase 17-like A
13532 Usp17lc; ubiquitin specific peptidase 17-like C
381944 Usp17lb; ubiquitin specific peptidase 17-like B
384701 Usp17ld; ubiquitin specific peptidase 17-like D
625530 Usp17le; ubiquitin specific peptidase 17-like E
24110 Usp18; ubiquitin specific peptidase 18
71472 Usp19; ubiquitin specific peptidase 19
170822 Usp33; ubiquitin specific peptidase 33
74270 Usp20; ubiquitin specific peptidase 20
30940 Usp25; ubiquitin specific peptidase 25
57775 Usp29; ubiquitin specific peptidase 29
83563 Usp26; ubiquitin specific peptidase 26
319651 Usp37; ubiquitin specific peptidase 37
100756 Usp30; ubiquitin specific peptidase 30
76179 Usp31; ubiquitin specific peptidase 31
17847 Usp34; ubiquitin specific peptidase 34
244144 Usp35; ubiquitin specific peptidase 35
74841 Usp38; ubiquitin specific peptidase 38
72344 Usp36; ubiquitin specific peptidase 36
76800 Usp42; ubiquitin specific peptidase 42
216835 Usp43; ubiquitin specific peptidase 43
74996 Usp47; ubiquitin specific peptidase 47
170707 Usp48; ubiquitin specific peptidase 48
21929 Tnfaip3; tumor necrosis factor, alpha-induced protein 3
170711 Otud7a; OTU domain containing 7A
229603 Otud7b; OTU domain containing 7B
70675 Vcpip1; valosin containing protein (p97)/p47 complex interacting protein 1
360216 Zranb1; zinc finger, RAN-binding domain containing 1
70527 Stambp; STAM binding protein
76630 Stambpl1; STAM binding protein like 1
227334 Usp40; ubiquitin specific peptidase 40
235441 Usp3; ubiquitin specific peptidase 3
54644 Otud5; OTU domain containing 5
71198 Otud1; OTU domain containing 1
73162 Otud3; OTU domain containing 3
73945 Otud4; OTU domain containing 4
66124 Josd2; Josephin domain containing 2
74158 Josd1; Josephin domain containing 1
408193 Otud6a; OTU domain containing 6A
72201 Otud6b; OTU domain containing 6B
432940 Otulin; OTU deubiquitinase with linear linkage specificity
235323 Usp28; ubiquitin specific peptidase 28
14479 Usp15; ubiquitin specific peptidase 15
30941 Usp21; ubiquitin specific peptidase 21
66960 Mindy3; MINDY lysine 48 deubiquitinase 3
330323 Mindy4; MINDY lysine 48 deubiquitinase 4
78825 Desi2; desumoylating isopeptidase 2
72580 Zup1; zinc finger containing ubiquitin peptidase 1
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K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
K05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]
K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
K09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]
K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
K11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]
K11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12]
K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
K11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]
K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
K11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]
K11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]
K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
K13716 OTUD1; OTU domain-containing protein 1 [EC:3.4.19.12]
K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
K13718 OTUD4; OTU domain-containing protein 4 [EC:3.4.19.12]
K15235 JOSD; josephin [EC:3.4.19.12]
K15235 JOSD; josephin [EC:3.4.19.12]
K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
K18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]
K21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]
K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
K24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]
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3.4.19.13 glutathione gamma-glutamate hydrolase
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3.4.19.14 leukotriene-C4 hydrolase
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3.4.19.15 desampylase
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3.4.19.16 glucosinolate gamma-glutamyl hydrolase
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3.4.21 Serine endopeptidases
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3.4.22 Cysteine endopeptidases
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3.4.23 Aspartic endopeptidases
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3.4.24 Metalloendopeptidases
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3.4.25 Threonine endopeptidases
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3.4.26 Glutamic endopeptidases
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3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
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3.6 Acting on acid anhydrides
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3.7 Acting on carbon-carbon bonds
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3.8 Acting on halide bonds
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3.9 Acting on phosphorus-nitrogen bonds
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3.10 Acting on sulfur-nitrogen bonds
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3.11 Acting on carbon-phosphorus bonds
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3.12 Acting on sulfur-sulfur bonds
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3.13 Acting on carbon-sulfur bonds
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4. Lyases
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5. Isomerases
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6. Ligases
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7. Translocases
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