KEGG Orthology (KO) - Mycobacterium tuberculosis H37Rv

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 09100 Metabolism

 





   09101 Carbohydrate metabolism





     00010 Glycolysis / Gluconeogenesis [PATH:mtu00010]





     00020 Citrate cycle (TCA cycle) [PATH:mtu00020]





       Rv0889c citA; citrate synthase 2
       Rv0896 gltA2; citrate synthase 1
       Rv1131 prpC; methylcitrate synthase PrpC
       Rv1475c acn; iron-regulated aconitate hydratase
       Rv0066c icd2; isocitrate dehydrogenase
       Rv3339c icd1; isocitrate dehydrogenase
       Rv1248c multifunctional 2-oxoglutarate dehydrogenase E1 component/2-oxoglutarate dehydrogenase dihydrolipoyllysine-residue succinyltransferase
       Rv0462 lpdC; dihydrolipoamide dehydrogenase
       Rv2455c 2-oxoglutarate oxidoreductase subunit KorA
       Rv2454c 2-oxoglutarate oxidoreductase subunit KorB
       Rv0952 sucD; succinyl-CoA ligase subunit alpha
       Rv0951 sucC; succinyl-CoA ligase subunit beta
       Rv3318 sdhA; succinate dehydrogenase flavoprotein subunit
       Rv0248c succinate dehydrogenase flavoprotein subunit
       Rv3319 sdhB; succinate dehydrogenase iron-sulphur protein subunit
       Rv0247c succinate dehydrogenase iron-sulfur subunit
       Rv3316 sdhC; succinate dehydrogenase cytochrome B-556 subunit
       Rv3317 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit
       Rv1552 frdA; fumarate reductase flavoprotein subunit
       Rv1553 frdB; fumarate reductase iron-sulfur subunit
       Rv1554 frdC; fumarate reductase membrane anchor subunit
       Rv1555 frdD; fumarate reductase membrane anchor subunit
       Rv1098c fum; fumarate hydratase
       Rv1240 mdh; malate dehydrogenase
       Rv2852c mqo; malate:quinone oxidoreductase
       Rv2967c pca; pyruvate carboxylase
       Rv0211 pckA; phosphoenolpyruvate carboxykinase
       Rv2241 aceE; pyruvate dehydrogenase E1 component
       Rv2215 dlaT; pyruvate dehydrogenase E2 component dihydrolipoamide acyltransferase



K01647 CS; citrate synthase [EC:2.3.3.1]
K01647 CS; citrate synthase [EC:2.3.3.1]
K01647 CS; citrate synthase [EC:2.3.3.1]
K01681 ACO; aconitate hydratase [EC:4.2.1.3]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K01616 kgd; multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
K00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]
K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]





     00030 Pentose phosphate pathway [PATH:mtu00030]





     00040 Pentose and glucuronate interconversions [PATH:mtu00040]





     00051 Fructose and mannose metabolism [PATH:mtu00051]





     00052 Galactose metabolism [PATH:mtu00052]





     00053 Ascorbate and aldarate metabolism [PATH:mtu00053]





     00500 Starch and sucrose metabolism [PATH:mtu00500]





     00520 Amino sugar and nucleotide sugar metabolism [PATH:mtu00520]





     00620 Pyruvate metabolism [PATH:mtu00620]





     00630 Glyoxylate and dicarboxylate metabolism [PATH:mtu00630]





     00640 Propanoate metabolism [PATH:mtu00640]





     00650 Butanoate metabolism [PATH:mtu00650]





       Rv1323 fadA4; acetyl-CoA acetyltransferase
       Rv1074c fadA3; beta-ketoacyl CoA thiolase FadA
       Rv1867 hypothetical protein
       Rv3546 fadA5; acetyl-CoA acetyltransferase FadA
       Rv0859 acyltransferase
       Rv0914c lipid carrier protein or keto acyl-CoA thiolase
       Rv3523 ltp3; lipid carrier protein
       Rv0243 fadA2; acetyl-CoA acetyltransferase FadA
       Rv3556c fadA6; acetyl-CoA acetyltransferase FadA
       Rv1715 fadB3; 3-hydroxybutyryl-CoA dehydrogenase FadB
       Rv0468 fadB2; 3-hydroxybutyryl-CoA dehydrogenase
       Rv0860 fadB; fatty oxidation protein FadB
       Rv1070c echA8; enoyl-CoA hydratase EchA8
       Rv2486 echA14; enoyl-CoA hydratase EchA14
       Rv1472 echA12; enoyl-CoA hydratase EchA12
       Rv3039c echA17; enoyl-CoA hydratase EchA17
       Rv3535c hsaG; acetaldehyde dehydrogenase
       Rv3318 sdhA; succinate dehydrogenase flavoprotein subunit
       Rv0248c succinate dehydrogenase flavoprotein subunit
       Rv3319 sdhB; succinate dehydrogenase iron-sulphur protein subunit
       Rv0247c succinate dehydrogenase iron-sulfur subunit
       Rv3316 sdhC; succinate dehydrogenase cytochrome B-556 subunit
       Rv3317 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit
       Rv1552 frdA; fumarate reductase flavoprotein subunit
       Rv1553 frdB; fumarate reductase iron-sulfur subunit
       Rv1554 frdC; fumarate reductase membrane anchor subunit
       Rv1555 frdD; fumarate reductase membrane anchor subunit
       Rv3432c gadB; glutamate decarboxylase GadB
       Rv2589 gabT; 4-aminobutyrate aminotransferase
       Rv0234c gabD1; succinate-semialdehyde dehydrogenase
       Rv1731 gabD2; succinate-semialdehyde dehydrogenase
       Rv2455c 2-oxoglutarate oxidoreductase subunit KorA
       Rv2454c 2-oxoglutarate oxidoreductase subunit KorB
       Rv2504c scoA; succinyl-CoA:3-ketoacid-CoA transferase subunit A
       Rv2503c scoB; succinyl-CoA:3-ketoacid-CoA transferase subunit B
       Rv3003c ilvB1; acetolactate synthase large subunit IlvB
       Rv3470c ilvB2; acetolactate synthase large subunit
       Rv3509c ilvX; acetohydroxyacid synthase large subunit
       Rv3002c ilvN; acetolactate synthase small subunit



K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
K04073 mhpF; acetaldehyde dehydrogenase [EC:1.2.1.10]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15]
K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]





     00660 C5-Branched dibasic acid metabolism [PATH:mtu00660]





     00562 Inositol phosphate metabolism [PATH:mtu00562]





 







   09102 Energy metabolism





     00190 Oxidative phosphorylation [PATH:mtu00190]





       Rv3145 nuoA; NADH-quinone oxidoreductase subunit A
       Rv3146 nuoB; NADH-quinone oxidoreductase subunit B
       Rv3147 nuoC; NADH-quinone oxidoreductase subunit C
       Rv3148 nuoD; NADH-quinone oxidoreductase subunit D
       Rv3149 nuoE; NADH-quinone oxidoreductase subunit E
       Rv3150 nuoF; NADH-quinone oxidoreductase subunit F
       Rv3151 nuoG; NADH-quinone oxidoreductase subunit G
       Rv3152 nuoH; NADH-quinone oxidoreductase subunit H
       Rv3153 nuoI; NADH-quinone oxidoreductase subunit I
       Rv3154 nuoJ; NADH-quinone oxidoreductase subunit J
       Rv3155 nuoK; NADH-quinone oxidoreductase subunit K
       Rv3156 nuoL; NADH-quinone oxidoreductase subunit L
       Rv3157 nuoM; NADH-quinone oxidoreductase subunit M
       Rv3158 nuoN; NADH-quinone oxidoreductase subunit N
       Rv1812c dehydrogenase
       Rv0392c ndhA; NADH dehydrogenase NdhA
       Rv1854c ndh; NADH dehydrogenase
       Rv3318 sdhA; succinate dehydrogenase flavoprotein subunit
       Rv0248c succinate dehydrogenase flavoprotein subunit
       Rv3319 sdhB; succinate dehydrogenase iron-sulphur protein subunit
       Rv0247c succinate dehydrogenase iron-sulfur subunit
       Rv3316 sdhC; succinate dehydrogenase cytochrome B-556 subunit
       Rv3317 sdhD; succinate dehydrogenase hydrophobic membrane anchor subunit
       Rv1552 frdA; fumarate reductase flavoprotein subunit
       Rv1553 frdB; fumarate reductase iron-sulfur subunit
       Rv1554 frdC; fumarate reductase membrane anchor subunit
       Rv1555 frdD; fumarate reductase membrane anchor subunit
       Rv2195 qcrA; ubiquinol-cytochrome C reductase rieske iron-sulfur subunit
       Rv2196 qcrB; ubiquinol-cytochrome C reductase cytochrome subunit B
       Rv2194 qcrC; ubiquinol-cytochrome C reductase cytochrome subunit C
       Rv1451 protoheme IX farnesyltransferase
       Rv2199c cytochrome c oxidase polypeptide 4
       Rv2193 ctaE; cytochrome C oxidase subunit III
       Rv3043c ctaD; cytochrome C oxidase cytochrome 1
       Rv2200c ctaC; cytochrome C oxidase subunit II
       Rv1456c antibiotic ABC transporter permease
       Rv1623c cydA; cytochrome D ubiquinol oxidase subunit I CydA
       Rv1622c cydB; cytochrome D ubiquinol oxidase subunit II CydB
       Rv1308 atpA; ATP synthase subunit alpha
       Rv1310 atpD; ATP synthase subunit beta
       Rv1309 atpG; ATP synthase subunit gamma
       Rv1307 atpH; ATP synthase subunit b/delta
       Rv1311 atpC; ATP synthase subunit epsilon
       Rv1304 atpB; ATP synthase subunit A
       Rv1306 atpF; ATP synthase subunit B
       Rv1305 atpE; ATP synthase subunit C
       Rv3628 ppa; inorganic pyrophosphatase
       Rv2984 ppk1; polyphosphate kinase
       Rv3232c ppk2; polyphosphate kinase



K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00241 sdhC; succinate dehydrogenase cytochrome b subunit
K00242 sdhD; succinate dehydrogenase membrane anchor subunit
K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
K00246 frdC; succinate dehydrogenase subunit C
K00247 frdD; succinate dehydrogenase subunit D
K03890 qcrA; quinol---cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K03891 qcrB; quinol---cytochrome-c reductase cytochrome b subunit [EC:7.1.1.8]
K03889 qcrC; quinol---cytochrome-c reductase cytochrome c subunit [EC:7.1.1.8]
K02257 COX10; heme o synthase [EC:2.5.1.141]
K27109 ctaF; cytochrome c oxidase subunit IV [EC:7.1.1.9]
K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
K02259 COX15; heme a synthase [EC:1.17.99.9]
K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
K02109 ATPF0B; F-type H+-transporting ATPase subunit b
K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
K02108 ATPF0A; F-type H+-transporting ATPase subunit a
K02109 ATPF0B; F-type H+-transporting ATPase subunit b
K02110 ATPF0C; F-type H+-transporting ATPase subunit c
K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]





     00195 Photosynthesis





     00196 Photosynthesis - antenna proteins





     00710 Carbon fixation in photosynthetic organisms





     00720 Carbon fixation pathways in prokaryotes





     00680 Methane metabolism [PATH:mtu00680]





     00910 Nitrogen metabolism [PATH:mtu00910]





     00920 Sulfur metabolism [PATH:mtu00920]





 







   09103 Lipid metabolism





 







   09104 Nucleotide metabolism





 







   09105 Amino acid metabolism





 







   09106 Metabolism of other amino acids





 







   09107 Glycan biosynthesis and metabolism





 







   09108 Metabolism of cofactors and vitamins





 







   09109 Metabolism of terpenoids and polyketides





 







   09110 Biosynthesis of other secondary metabolites





 







   09111 Xenobiotics biodegradation and metabolism





 







   09112 Not included in regular maps





 







 09120 Genetic Information Processing





 







 09130 Environmental Information Processing





 







 09140 Cellular Processes





 







 09150 Organismal Systems





 







 09160 Human Diseases





 







 09180 Brite Hierarchies





 







 09190 Not Included in Pathway or Brite













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Last updated: April 16, 2024