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KO |
09100 Metabolism
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09101 Carbohydrate metabolism
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09102 Energy metabolism
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09103 Lipid metabolism
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00061 Fatty acid biosynthesis [PATH:myd00061]
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00062 Fatty acid elongation [PATH:myd00062]
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00071 Fatty acid degradation [PATH:myd00071]
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00073 Cutin, suberine and wax biosynthesis
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00100 Steroid biosynthesis [PATH:myd00100]
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00120 Primary bile acid biosynthesis [PATH:myd00120]
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00121 Secondary bile acid biosynthesis
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00140 Steroid hormone biosynthesis [PATH:myd00140]
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00561 Glycerolipid metabolism [PATH:myd00561]
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00564 Glycerophospholipid metabolism [PATH:myd00564]
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00565 Ether lipid metabolism [PATH:myd00565]
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00600 Sphingolipid metabolism [PATH:myd00600]
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00590 Arachidonic acid metabolism [PATH:myd00590]
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00591 Linoleic acid metabolism [PATH:myd00591]
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00592 alpha-Linolenic acid metabolism [PATH:myd00592]
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01040 Biosynthesis of unsaturated fatty acids [PATH:myd01040]
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102770278 ELOVL1; ELOVL fatty acid elongase 1
102763123 ELOVL2; ELOVL fatty acid elongase 2
102768695 ELOVL3; ELOVL fatty acid elongase 3
102756238 ELOVL4; ELOVL fatty acid elongase 4
102762453 ELOVL5; ELOVL fatty acid elongase 5
102758316 ELOVL6; ELOVL fatty acid elongase 6
102763394 ELOVL7; ELOVL fatty acid elongase 7
102766960 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12
102758451 very-long-chain 3-oxoacyl-CoA reductase-like
102761248 HACD2; 3-hydroxyacyl-CoA dehydratase 2
102767778 HACD1; 3-hydroxyacyl-CoA dehydratase 1
102765511 HACD4; 3-hydroxyacyl-CoA dehydratase 4
102765145 HACD3; 3-hydroxyacyl-CoA dehydratase 3
102751823 TECR; trans-2,3-enoyl-CoA reductase
102759722 SCD; stearoyl-CoA desaturase
102758244 SCD5; stearoyl-CoA desaturase 5
102773468 FADS2; fatty acid desaturase 2
102773181 FADS1; fatty acid desaturase 1
102752805 ACOX1; acyl-CoA oxidase 1
102766056 ACOX3; acyl-CoA oxidase 3, pristanoyl
102767159 HSD17B4; hydroxysteroid 17-beta dehydrogenase 4
102759768 ACAA1; acetyl-CoA acyltransferase 1
102765227 SCP2; sterol carrier protein 2
102759368 ACOT2; acyl-coenzyme A thioesterase 1
102759648 ACOT4; acyl-CoA thioesterase 4
102752282 ACOT7; acyl-CoA thioesterase 7
102764710 acyl-coenzyme A amino acid N-acyltransferase 2
102764048 acyl-coenzyme A amino acid N-acyltransferase 2
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K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K12405 HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119]
K07513 ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
K08764 SCP2; sterol carrier protein 2 [EC:2.3.1.176]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
K00659 BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
K00659 BAAT; bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
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09104 Nucleotide metabolism
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system
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04010 MAPK signaling pathway [PATH:myd04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:myd04012]
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04014 Ras signaling pathway [PATH:myd04014]
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04015 Rap1 signaling pathway [PATH:myd04015]
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04310 Wnt signaling pathway [PATH:myd04310]
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04330 Notch signaling pathway [PATH:myd04330]
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04340 Hedgehog signaling pathway [PATH:myd04340]
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04341 Hedgehog signaling pathway - fly
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04350 TGF-beta signaling pathway [PATH:myd04350]
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04390 Hippo signaling pathway [PATH:myd04390]
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04391 Hippo signaling pathway - fly
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04392 Hippo signaling pathway - multiple species [PATH:myd04392]
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04370 VEGF signaling pathway [PATH:myd04370]
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04371 Apelin signaling pathway [PATH:myd04371]
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04630 JAK-STAT signaling pathway [PATH:myd04630]
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04064 NF-kappa B signaling pathway [PATH:myd04064]
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04668 TNF signaling pathway [PATH:myd04668]
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04066 HIF-1 signaling pathway [PATH:myd04066]
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04068 FoxO signaling pathway [PATH:myd04068]
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04020 Calcium signaling pathway [PATH:myd04020]
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04070 Phosphatidylinositol signaling system [PATH:myd04070]
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04072 Phospholipase D signaling pathway [PATH:myd04072]
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04071 Sphingolipid signaling pathway [PATH:myd04071]
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04024 cAMP signaling pathway [PATH:myd04024]
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04022 cGMP-PKG signaling pathway [PATH:myd04022]
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04151 PI3K-Akt signaling pathway [PATH:myd04151]
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04152 AMPK signaling pathway [PATH:myd04152]
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102763957 MAP3K7; mitogen-activated protein kinase kinase kinase 7
102767396 STK11; serine/threonine kinase 11
102765964 CAB39L; calcium binding protein 39 like
102761193 CAB39; calcium binding protein 39
102753563 STRADA; STE20-related kinase adaptor alpha
102760986 STRADB; STE20-related kinase adaptor beta
102759608 LEP; leptin
102757565 LEPR; leptin receptor
102752773 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
102767266 ADRA1A; adrenoceptor alpha 1A
102753417 ADIPOQ; adiponectin, C1Q and collagen domain containing
102773758 ADIPOR2; adiponectin receptor 2
102756180 ADIPOR1; adiponectin receptor 1
102768354 adiponectin receptor protein 1
102774877 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
102759339 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
102766305 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
102768765 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
102762694 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
102761682 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
102759388 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
102751621 PFKFB1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
102772244 PFKFB2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
102768559 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
102772908 FBP2; fructose-1,6-bisphosphatase isozyme 2
102770609 FBP1; fructose-bisphosphatase 1
102768013 PFKM; phosphofructokinase, muscle
102753287 PFKP; phosphofructokinase, platelet
102757968 PFKL; phosphofructokinase, liver type
102760735 HNF4A; hepatocyte nuclear factor 4 alpha
102765471 G6PC3; glucose-6-phosphatase catalytic subunit 3
102759248 G6PC; glucose-6-phosphatase catalytic subunit
102774116 G6PC2; glucose-6-phosphatase catalytic subunit 2
102754608 PCK1; phosphoenolpyruvate carboxykinase 1
102771630 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
102770919 CRTC2; CREB regulated transcription coactivator 2
102754892 CREB1; cAMP responsive element binding protein 1
102764297 CREB3L3; cAMP responsive element binding protein 3 like 3
102768092 CREB3L1; cAMP responsive element binding protein 3 like 1
102772259 CREB3L4; cAMP responsive element binding protein 3 like 4
102773515 CREB3L2; cAMP responsive element binding protein 3 like 2
102762431 CREB3; cAMP responsive element binding protein 3
102769297 CREB5; cAMP responsive element binding protein 5
102770595 PPARGC1A; PPARG coactivator 1 alpha
102762479 ELAVL1; ELAV like RNA binding protein 1
102759793 CCND1; cyclin D1
102758841 CCNA2; cyclin A2
102752341 CCNA1; cyclin A1
102761531 EEF2K; eukaryotic elongation factor 2 kinase
102765734 EEF2; eukaryotic translation elongation factor 2
102766094 FOXO1; forkhead box O1
102751393 FOXO3; forkhead box O3
102756748 SIRT1; sirtuin 1
102751885 SLC2A4; solute carrier family 2 member 4
102771674 GYS2; glycogen synthase 2
102775147 GYS1; glycogen synthase 1
102764534 LIPE; lipase E, hormone sensitive type
102767367 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase
102767914 SREBF1; sterol regulatory element binding transcription factor 1
102761714 FASN; fatty acid synthase
102766302 ACACA; acetyl-CoA carboxylase alpha
102759722 SCD; stearoyl-CoA desaturase
102758244 SCD5; stearoyl-CoA desaturase 5
102759463 ACACB; acetyl-CoA carboxylase beta
102759504 CPT1A; carnitine palmitoyltransferase 1A
102764960 CPT1B; carnitine palmitoyltransferase 1B
102770000 CPT1C; carnitine palmitoyltransferase 1C
102758921 CIDEA; cell death-inducing DFFA-like effector a
102762679 PPP2CA; protein phosphatase 2 catalytic subunit alpha
102771922 PPP2CB; protein phosphatase 2 catalytic subunit beta
102762854 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
102758648 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
102773953 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
102772844 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
102756870 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
102774976 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
102765775 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
102753112 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
102767336 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
102761846 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
102767522 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
102758104 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
102773081 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
102771902 TBC1D1; TBC1 domain family member 1
102773842 RAB2A; RAB2A, member RAS oncogene family
102754443 RAB8A; RAB8A, member RAS oncogene family
102762935 ras-related protein Rab-8A
102752687 RAB10; RAB10, member RAS oncogene family
102766733 RAB11B; RAB11B, member RAS oncogene family
102775092 RAB14; RAB14, member RAS oncogene family
102773631 CFTR; cystic fibrosis transmembrane conductance regulator
102766978 CD36; CD36 molecule
102752580 IGF1; insulin like growth factor 1
102770795 IGF1R; insulin like growth factor 1 receptor
102753598 INS; insulin
102766590 INSR; insulin receptor
102752666 IRS1; insulin receptor substrate 1
102753060 IRS2; insulin receptor substrate 2
102753243 IRS4; insulin receptor substrate 4
102764343 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
102766356 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
102758951 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
102763670 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
102753036 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
102760468 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
102756818 PDPK1; 3-phosphoinositide dependent protein kinase 1
102772266 AKT3; AKT serine/threonine kinase 3
102773065 AKT2; AKT serine/threonine kinase 2
102770093 TSC2; tuberous sclerosis 2
102752713 TSC1; tuberous sclerosis 1
102758475 RHEB; Ras homolog enriched in brain
102766933 MTOR; mechanistic target of rapamycin
102754661 RPTOR; regulatory associated protein of MTOR complex 1
102758931 AKT1S1; AKT1 substrate 1
102763828 RPS6KB2; ribosomal protein S6 kinase B2
102775361 RPS6KB1; ribosomal protein S6 kinase B1
102758662 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
102771129 PPARG; peroxisome proliferator activated receptor gamma
102767979 ULK1; unc-51 like autophagy activating kinase 1
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K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04135 ADRA1A; adrenergic receptor alpha-1A
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K13088 ELAVL1; ELAV-like protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K25893 CIDEA; cell death activator CIDE-A
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K18341 TBC1D1; TBC1 domain family member 1
K07877 RAB2A; Ras-related protein Rab-2A
K07901 RAB8A; Ras-related protein Rab-8A
K07901 RAB8A; Ras-related protein Rab-8A
K07903 RAB10; Ras-related protein Rab-10
K07905 RAB11B; Ras-related protein Rab-11B
K07881 RAB14; Ras-related protein Rab-14
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K06259 CD36; CD36 antigen
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
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04150 mTOR signaling pathway [PATH:myd04150]
|
04075 Plant hormone signal transduction
|
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09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
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09150 Organismal Systems
|
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09151 Immune system
|
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|
09152 Endocrine system
|
04911 Insulin secretion [PATH:myd04911]
|
04910 Insulin signaling pathway [PATH:myd04910]
|
04922 Glucagon signaling pathway [PATH:myd04922]
|
04923 Regulation of lipolysis in adipocytes [PATH:myd04923]
|
04920 Adipocytokine signaling pathway [PATH:myd04920]
|
03320 PPAR signaling pathway [PATH:myd03320]
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102766978 CD36; CD36 molecule
102769438 SLC27A1; solute carrier family 27 member 1
102774414 SLC27A4; solute carrier family 27 member 4
102767645 SLC27A2; solute carrier family 27 member 2
102751593 SLC27A5; solute carrier family 27 member 5
102775342 SLC27A6; solute carrier family 27 member 6
102764924 FABP1; fatty acid binding protein 1
102767389 FABP2; fatty acid binding protein 2
102772117 FABP3; fatty acid binding protein 3
102767429 fatty acid-binding protein, heart-like
102756654 FABP4; fatty acid-binding protein, adipocyte
102760137 FABP9; fatty acid-binding protein 9
102755633 FABP5; fatty acid binding protein 5
102758382 FABP6; fatty acid binding protein 6
102770654 FABP7; fatty acid binding protein 7
102773112 PPARA; peroxisome proliferator activated receptor alpha
102762226 RXRA; retinoid X receptor alpha
102766946 RXRB; retinoid X receptor beta
102765652 RXRG; retinoid X receptor gamma
102769682 PPARD; peroxisome proliferator activated receptor delta
102771129 PPARG; peroxisome proliferator activated receptor gamma
102771816 HMGCS2; 3-hydroxy-3-methylglutaryl-CoA synthase 2
102767700 HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1
102762628 APOA1; apolipoprotein A1
102774574 APOA2; apolipoprotein A2
102772091 APOC3; apolipoprotein C3
102762057 APOA5; apolipoprotein A5
102766396 PLTP; phospholipid transfer protein
102763453 ME3; malic enzyme 3
102751926 ME1; malic enzyme 1
102773468 FADS2; fatty acid desaturase 2
102759722 SCD; stearoyl-CoA desaturase
102758244 SCD5; stearoyl-CoA desaturase 5
102775453 cholesterol 7-alpha-monooxygenase
102765424 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase
102755020 NR1H3; nuclear receptor subfamily 1 group H member 3
102761397 sterol 26-hydroxylase, mitochondrial
102761616 DBI; diazepam binding inhibitor, acyl-CoA binding protein
102771561 diazepam-binding inhibitor-like 5
102759852 LPL; lipoprotein lipase
102770310 ACSL4; acyl-CoA synthetase long-chain family member 4
102761529 ACSL1; acyl-CoA synthetase long-chain family member 1
102765104 ACSL5; acyl-CoA synthetase long-chain family member 5
102768995 ACSL6; acyl-CoA synthetase long-chain family member 6
102773062 ACSL3; acyl-CoA synthetase long-chain family member 3
102754252 ACSBG2; acyl-CoA synthetase bubblegum family member 2
102759034 ACSBG1; acyl-CoA synthetase bubblegum family member 1
102755141 OLR1; oxidized low density lipoprotein receptor 1
102771761 EHHADH; enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
102774956 cytochrome P450 4A6
102759768 ACAA1; acetyl-CoA acyltransferase 1
102765227 SCP2; sterol carrier protein 2
102752805 ACOX1; acyl-CoA oxidase 1
102766056 ACOX3; acyl-CoA oxidase 3, pristanoyl
102766328 ACOX2; acyl-CoA oxidase 2
102759504 CPT1A; carnitine palmitoyltransferase 1A
102764960 CPT1B; carnitine palmitoyltransferase 1B
102770000 CPT1C; carnitine palmitoyltransferase 1C
102766661 CPT2; carnitine palmitoyltransferase 2
102757895 ACADL; acyl-CoA dehydrogenase, long chain
102759069 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain
102769400 ANGPTL4; angiopoietin like 4
102753836 SORBS1; sorbin and SH3 domain containing 1
102754990 PLIN1; perilipin 1
102759588 PLIN2; perilipin 2
102755310 PLIN4; perilipin 4
102761352 PLIN5; perilipin 5
102753417 ADIPOQ; adiponectin, C1Q and collagen domain containing
102770236 MMP1; matrix metallopeptidase 1
102760746 UCP1; uncoupling protein 1
102764668 ILK; integrin linked kinase
102756818 PDPK1; 3-phosphoinositide dependent protein kinase 1
102754608 PCK1; phosphoenolpyruvate carboxykinase 1
102771630 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
102770794 GK; glycerol kinase
102769589 GK2; glycerol kinase 2
102769532 glycerol kinase
102757593 AQP7; aquaporin 7
|
K06259 CD36; CD36 antigen
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08748 SLC27A5; solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
K08749 SLC27A6; solute carrier family 27 (fatty acid transporter), member 6
K08750 FABP1; fatty acid-binding protein 1, liver
K08751 FABP2; fatty acid-binding protein 2, intestinal
K08752 FABP3; fatty acid-binding protein 3, muscle and heart
K08752 FABP3; fatty acid-binding protein 3, muscle and heart
K08753 FABP4; fatty acid-binding protein 4, adipocyte
K08753 FABP4; fatty acid-binding protein 4, adipocyte
K08754 FABP5; fatty acid-binding protein 5, epidermal
K08755 FABP6; fatty acid-binding protein 6, ileal (gastrotropin)
K08756 FABP7; fatty acid-binding protein 7, brain
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
K08757 APOA1; apolipoprotein A-I
K08758 APOA2; apolipoprotein A-II
K08759 APOC3; apolipoprotein C-III
K09025 APOA5; apolipoprotein A-V
K08761 PLTP; phospholipid transfer protein
K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K07431 CYP8B1; sterol 12-alpha-hydroxylase [EC:1.14.14.139]
K08536 NR1H3; liver X receptor alpha
K00488 CYP27A1; cholestanetriol 26-monooxygenase [EC:1.14.15.15]
K08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
K08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K08763 OLR1; oxidised low-density lipoprotein receptor 1
K07514 EHHADH; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8]
K07425 CYP4A; long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K07513 ACAA1; acetyl-CoA acyltransferase 1 [EC:2.3.1.16]
K08764 SCP2; sterol carrier protein 2 [EC:2.3.1.176]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K10214 ACOX2; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K08766 CPT2; carnitine O-palmitoyltransferase 2 [EC:2.3.1.21]
K00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
K08767 ANGPTL4; angiopoietin-like 4
K06086 SORBS1; sorbin and SH3 domain containing protein 1
K08768 PLIN1; perilipin-1
K17284 PLIN2; perilipin-2
K20254 PLIN4; perilipin-4
K20255 PLIN5; perilipin-5
K07296 ADIPOQ; adiponectin
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K08769 UCP1; solute carrier family 25 (mitochondrial uncoupling protein), member 7
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00864 glpK; glycerol kinase [EC:2.7.1.30]
K00864 glpK; glycerol kinase [EC:2.7.1.30]
K00864 glpK; glycerol kinase [EC:2.7.1.30]
K08771 AQP7; aquaporin-7
|
04929 GnRH secretion [PATH:myd04929]
|
04912 GnRH signaling pathway [PATH:myd04912]
|
04913 Ovarian steroidogenesis [PATH:myd04913]
|
04915 Estrogen signaling pathway [PATH:myd04915]
|
04914 Progesterone-mediated oocyte maturation [PATH:myd04914]
|
04917 Prolactin signaling pathway [PATH:myd04917]
|
04921 Oxytocin signaling pathway [PATH:myd04921]
|
04926 Relaxin signaling pathway [PATH:myd04926]
|
04935 Growth hormone synthesis, secretion and action [PATH:myd04935]
|
04918 Thyroid hormone synthesis [PATH:myd04918]
|
04919 Thyroid hormone signaling pathway [PATH:myd04919]
|
04928 Parathyroid hormone synthesis, secretion and action [PATH:myd04928]
|
04916 Melanogenesis [PATH:myd04916]
|
04924 Renin secretion [PATH:myd04924]
|
04614 Renin-angiotensin system [PATH:myd04614]
|
04925 Aldosterone synthesis and secretion [PATH:myd04925]
|
04927 Cortisol synthesis and secretion [PATH:myd04927]
|
|
|
09153 Circulatory system
|
|
|
09154 Digestive system
|
|
|
09155 Excretory system
|
|
|
09156 Nervous system
|
|
|
09157 Sensory system
|
|
|
09158 Development and regeneration
|
|
|
09149 Aging
|
|
|
09159 Environmental adaptation
|
|
|
09160 Human Diseases
|
|
|
09161 Cancer: overview
|
|
|
09162 Cancer: specific types
|
|
|
09172 Infectious disease: viral
|
|
|
09171 Infectious disease: bacterial
|
|
|
09174 Infectious disease: parasitic
|
|
|
09163 Immune disease
|
|
|
09164 Neurodegenerative disease
|
|
|
09165 Substance dependence
|
|
|
09166 Cardiovascular disease
|
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:myd04930]
|
04940 Type I diabetes mellitus [PATH:myd04940]
|
04950 Maturity onset diabetes of the young [PATH:myd04950]
|
04936 Alcoholic liver disease [PATH:myd04936]
|
102757592 C1QA; complement C1q A chain
102756834 C1QB; complement C1q B chain
102757117 C1QC; complement C1q C chain
102766284 C2; complement C2
102774999 C4A; complement C4-A
102754026 complement C3-like
102752376 C3AR1; complement C3a receptor 1
102774153 C5; complement C5
102755212 C5a anaphylatoxin chemotactic receptor 1
102754536 LBP; lipopolysaccharide binding protein
102773178 CD14; CD14 molecule
102751815 LY96; lymphocyte antigen 96
102756242 TLR4; toll like receptor 4
102767941 toll/interleukin-1 receptor domain-containing adapter protein-like
102774520 TIRAP; TIR domain containing adaptor protein
107183283 MYD88; myeloid differentiation primary response 88
102754676 IRAK4; interleukin 1 receptor associated kinase 4
102765985 IRAK1; interleukin 1 receptor associated kinase 1
102765934 TRAF6; TNF receptor associated factor 6
102752149 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
102770532 TAB2; TGF-beta activated kinase 1/MAP3K7 binding protein 2
102763957 MAP3K7; mitogen-activated protein kinase kinase kinase 7
102760888 CHUK; conserved helix-loop-helix ubiquitous kinase
102773824 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
102772051 IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma
102763089 NFKBIA; NFKB inhibitor alpha
102770704 RELA; RELA proto-oncogene, NF-kB subunit
102770715 NFKB1; nuclear factor kappa B subunit 1
102758774 TNF; tumor necrosis factor
102769803 IL1B; interleukin 1 beta
102760336 IL6; interleukin 6
102753538 IL12A; interleukin 12A
102756968 IL12B; interleukin 12B
102761051 CXCL8; C-X-C motif chemokine ligand 8
102754468 TICAM1; toll like receptor adaptor molecule 1
102771530 TRAF3; TNF receptor associated factor 3
102760291 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
102769631 TBK1; TANK binding kinase 1
102760165 IRF3; interferon regulatory factor 3
102766079 interferon alpha-1
102765800 IFNB1; interferon beta 1
102757996 IL17A; interleukin 17A
102758604 IL17RA; interleukin 17 receptor A
102767657 IL17RC; interleukin 17 receptor C
102760182 growth-regulated protein homolog gamma
102759597 FASLG; Fas ligand
102760302 FAS; Fas cell surface death receptor
102756704 FADD; Fas associated via death domain
102768884 TNFRSF1A; TNF receptor superfamily member 1A
102757347 TRADD; TNFRSF1A associated via death domain
102761550 CASP8; caspase 8
102760961 CASP3; caspase 3
102770973 RIPK1; receptor interacting serine/threonine kinase 1
102772625 TAB3; TGF-beta activated kinase 1/MAP3K7 binding protein 3
102767914 SREBF1; sterol regulatory element binding transcription factor 1
102761714 FASN; fatty acid synthase
102766302 ACACA; acetyl-CoA carboxylase alpha
102759722 SCD; stearoyl-CoA desaturase
102758244 SCD5; stearoyl-CoA desaturase 5
102752943 LPIN2; lipin 2
102756961 LPIN3; lipin 3
102764739 LPIN1; lipin 1
102756748 SIRT1; sirtuin 1
102769933 TRA2B; transformer 2 beta homolog (Drosophila)
102756460 TRA2A; transformer 2 alpha homolog
102753417 ADIPOQ; adiponectin, C1Q and collagen domain containing
102773758 ADIPOR2; adiponectin receptor 2
102756180 ADIPOR1; adiponectin receptor 1
102768354 adiponectin receptor protein 1
102752773 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
102774877 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
102759339 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
102766305 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
102768765 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
102762694 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
102761682 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
102759388 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
102766094 FOXO1; forkhead box O1
102751393 FOXO3; forkhead box O3
102770595 PPARGC1A; PPARG coactivator 1 alpha
102773112 PPARA; peroxisome proliferator activated receptor alpha
102759504 CPT1A; carnitine palmitoyltransferase 1A
102774563 ACADVL; acyl-CoA dehydrogenase, very long chain
102759069 ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain
102752805 ACOX1; acyl-CoA oxidase 1
102766056 ACOX3; acyl-CoA oxidase 3, pristanoyl
102764924 FABP1; fatty acid binding protein 1
102757174 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
102757746 alcohol dehydrogenase S chain
102752501 ADH4; alcohol dehydrogenase 4
102758302 alcohol dehydrogenase 4-like
102752786 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
102752210 ADH6; alcohol dehydrogenase 6
102769497 ALDH3A2; aldehyde dehydrogenase 3 family member A2
102774541 ALDH1B1; aldehyde dehydrogenase 1 family member B1
102755288 ALDH2; aldehyde dehydrogenase 2 family (mitochondrial)
102763606 ALDH16A1; aldehyde dehydrogenase 16 family member A1
102754535 ALDH7A1; aldehyde dehydrogenase 7 family member A1
102768395 ALDH9A1; aldehyde dehydrogenase 9 family member A1
102760593 cytochrome P450 2E1
102759463 ACACB; acetyl-CoA carboxylase beta
102764960 CPT1B; carnitine palmitoyltransferase 1B
102770000 CPT1C; carnitine palmitoyltransferase 1C
102761671 NOX4; NADPH oxidase 4
102772266 AKT3; AKT serine/threonine kinase 3
102773065 AKT2; AKT serine/threonine kinase 2
102751662 GSK3B; glycogen synthase kinase 3 beta
102773658 CTNNB1; catenin beta 1
102757003 TCF7; transcription factor 7 (T-cell specific, HMG-box)
102768915 TCF7L1; transcription factor 7 like 1
102767014 TCF7L2; transcription factor 7 like 2
102767379 LEF1; lymphoid enhancer binding factor 1
102759793 CCND1; cyclin D1
102771311 MAP3K5; mitogen-activated protein kinase kinase kinase 5
102769098 MAP2K4; mitogen-activated protein kinase kinase 4
102760954 MAP2K7; mitogen-activated protein kinase kinase 7
102772062 MAPK9; mitogen-activated protein kinase 9
102764416 MAPK8; mitogen-activated protein kinase 8
102775351 mitogen-activated protein kinase 10
102765923 MAP2K3; mitogen-activated protein kinase kinase 3
102759247 MAP2K6; mitogen-activated protein kinase kinase 6
102770309 MAPK11; mitogen-activated protein kinase 11
102770021 MAPK12; mitogen-activated protein kinase 12
102755728 MAPK14; mitogen-activated protein kinase 14
102756012 MAPK13; mitogen-activated protein kinase 13
102762988 MAP3K14; mitogen-activated protein kinase kinase kinase 14
|
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03990 C3; complement component 3
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03994 C5; complement component 5
K04010 C5AR1; C5a anaphylatoxin chemotactic receptor 1
K05399 LBP; lipopolysaccharide-binding protein
K04391 CD14; monocyte differentiation antigen CD14
K05400 LY96; lymphocyte antigen 96
K10160 TLR4; toll-like receptor 4
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K10030 IL8; interleukin 8
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05489 IL17A; interleukin 17A
K05164 IL17RA; interleukin 17 receptor A
K05166 IL17RC; interleukin 17 receptor C
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K12793 MAP3K7IP3; TAK1-binding protein 3
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K12897 TRA2; transformer-2 protein
K12897 TRA2; transformer-2 protein
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K09479 ACADVL; very long chain acyl-CoA dehydrogenase [EC:1.3.8.9]
K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K00232 E1.3.3.6; acyl-CoA oxidase [EC:1.3.3.6]
K08750 FABP1; fatty acid-binding protein 1, liver
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K21423 NOX4; NADPH oxidase 4 [EC:1.6.3.-]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
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04932 Non-alcoholic fatty liver disease [PATH:myd04932]
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04931 Insulin resistance [PATH:myd04931]
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04933 AGE-RAGE signaling pathway in diabetic complications [PATH:myd04933]
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04934 Cushing syndrome [PATH:myd04934]
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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01000 Enzymes [BR:myd01000]
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01001 Protein kinases [BR:myd01001]
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01009 Protein phosphatases and associated proteins [BR:myd01009]
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01002 Peptidases and inhibitors [BR:myd01002]
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01003 Glycosyltransferases [BR:myd01003]
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01005 Lipopolysaccharide biosynthesis proteins
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01011 Peptidoglycan biosynthesis and degradation proteins
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01004 Lipid biosynthesis proteins [BR:myd01004]
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102761714 FASN; fatty acid synthase
102768403 MCAT; malonyl-CoA-acyl carrier protein transacylase
102763136 OXSM; 3-oxoacyl-ACP synthase, mitochondrial
102766960 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12
102758451 very-long-chain 3-oxoacyl-CoA reductase-like
102761248 HACD2; 3-hydroxyacyl-CoA dehydratase 2
102767778 HACD1; 3-hydroxyacyl-CoA dehydratase 1
102765511 HACD4; 3-hydroxyacyl-CoA dehydratase 4
102765145 HACD3; 3-hydroxyacyl-CoA dehydratase 3
102767284 PECR; peroxisomal trans-2-enoyl-CoA reductase
102751823 TECR; trans-2,3-enoyl-CoA reductase
102759672 OLAH; oleoyl-ACP hydrolase
102768095 PPT2; palmitoyl-protein thioesterase 2
102770643 PPT1; palmitoyl-protein thioesterase 1
102759368 ACOT2; acyl-coenzyme A thioesterase 1
102759648 ACOT4; acyl-CoA thioesterase 4
102753856 ACOT6; acyl-CoA thioesterase 6
102752282 ACOT7; acyl-CoA thioesterase 7
102767594 ACOT9; acyl-CoA thioesterase 9
102772883 ACOT11; acyl-CoA thioesterase 11
102774959 ACOT13; acyl-CoA thioesterase 13
102759722 SCD; stearoyl-CoA desaturase
102758244 SCD5; stearoyl-CoA desaturase 5
102763137 FADS3; fatty acid desaturase 3
102773181 FADS1; fatty acid desaturase 1
102773468 FADS2; fatty acid desaturase 2
102768904 DEGS1; delta 4-desaturase, sphingolipid 1
102761894 DEGS2; delta 4-desaturase, sphingolipid 2
102773700 FADS6; fatty acid desaturase 6
102770278 ELOVL1; ELOVL fatty acid elongase 1
102763123 ELOVL2; ELOVL fatty acid elongase 2
102756238 ELOVL4; ELOVL fatty acid elongase 4
102762453 ELOVL5; ELOVL fatty acid elongase 5
102758316 ELOVL6; ELOVL fatty acid elongase 6
102763394 ELOVL7; ELOVL fatty acid elongase 7
102768695 ELOVL3; ELOVL fatty acid elongase 3
102762213 ACSS1; acyl-CoA synthetase short-chain family member 1
102764737 ACSS2; acyl-CoA synthetase short-chain family member 2
102767259 ACSS3; acyl-CoA synthetase short-chain family member 3
102764845 AACS; acetoacetyl-CoA synthetase
102762433 acyl-coenzyme A synthetase ACSM1, mitochondrial
102755299 ACSM2A; acyl-coenzyme A synthetase ACSM2A, mitochondrial
102760086 ACSM4; acyl-coenzyme A synthetase ACSM4, mitochondrial
102755589 ACSM3; acyl-CoA synthetase medium-chain family member 3
102773394 ACSF2; acyl-CoA synthetase family member 2
102770310 ACSL4; acyl-CoA synthetase long-chain family member 4
102761529 ACSL1; acyl-CoA synthetase long-chain family member 1
102765104 ACSL5; acyl-CoA synthetase long-chain family member 5
102768995 ACSL6; acyl-CoA synthetase long-chain family member 6
102773062 ACSL3; acyl-CoA synthetase long-chain family member 3
102754252 ACSBG2; acyl-CoA synthetase bubblegum family member 2
102759034 ACSBG1; acyl-CoA synthetase bubblegum family member 1
102769438 SLC27A1; solute carrier family 27 member 1
102774414 SLC27A4; solute carrier family 27 member 4
102767645 SLC27A2; solute carrier family 27 member 2
102769952 SLC27A3; solute carrier family 27 member 3
102758159 AASDH; aminoadipate-semialdehyde dehydrogenase
102774467 GPAM; glycerol-3-phosphate acyltransferase, mitochondrial
102761765 GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial
102754070 GPAT4; glycerol-3-phosphate acyltransferase 4
102770982 GPAT3; glycerol-3-phosphate acyltransferase 3
102759634 AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2
102768385 AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1
102762071 ABHD5; abhydrolase domain containing 5
102757823 LCLAT1; lysocardiolipin acyltransferase 1
102775293 TAZ; tafazzin
102774453 MBOAT1; membrane bound O-acyltransferase domain containing 1
102766825 MBOAT2; membrane bound O-acyltransferase domain containing 2
102757678 AGPAT4; 1-acylglycerol-3-phosphate O-acyltransferase 4
102756653 AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3
102767459 LPCAT2; lysophosphatidylcholine acyltransferase 2
102774257 lysophosphatidylcholine acyltransferase 2B-like
102771533 LPCAT1; lysophosphatidylcholine acyltransferase 1
102766895 LPCAT4; lysophosphatidylcholine acyltransferase 4
102765716 LPGAT1; lysophosphatidylglycerol acyltransferase 1
102755432 LPCAT3; lysophosphatidylcholine acyltransferase 3
102763200 MBOAT7; membrane bound O-acyltransferase domain containing 7
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K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]
K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]
K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2]
K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]
K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]
K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]
K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]
K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]
K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]
K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-]
K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]
K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]
K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]
K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]
K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]
K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]
K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16]
K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]
K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]
K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]
K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]
K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-]
K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15]
K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]
K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51]
K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]
K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]
K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-]
K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]
K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]
K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]
K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]
K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]
K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]
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01008 Polyketide biosynthesis proteins
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01006 Prenyltransferases [BR:myd01006]
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01007 Amino acid related enzymes [BR:myd01007]
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00199 Cytochrome P450 [BR:myd00199]
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00194 Photosynthesis proteins
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09182 Protein families: genetic information processing
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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