Chromosome and Associated Proteins - Ornithorhynchus anatinus (platypus)

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     KO
 Eukaryotic type
   Sister chromatid cohesion proteins
   Meiosis-specific proteins
   Nucleosome assembly factors
   Histone modification proteins
     HATs (histone acetyltransferases)
     HAT complexes
     HDACs (histone deacetylases)
     HDAC complexes
     HMTs (histone methyltransferases)
       HKMTs (histone lysine methyltransferases)
         103168045 ASH1L; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase ASH1L
         100088528 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
         100078328 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X1
         100082943 EHMT2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase EHMT2
         100082851 EZH1; histone-lysine N-methyltransferase EZH1 isoform X1
         100073485 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
         100086068 KMT2A; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2A
         100074286 KMT2C; histone-lysine N-methyltransferase 2C isoform X1
         103165316 KMT2B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
         100077208 KMT2E; inactive histone-lysine N-methyltransferase 2E isoform X1
         100085446 NSD1; histone-lysine N-methyltransferase, H3 lysine-36 specific
         100086259 NSD2; histone-lysine N-methyltransferase NSD2
         100074284 NSD3; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD3
         100681503 PRDM2; PR domain zinc finger protein 2 isoform X1
         100084365 MECOM; histone-lysine N-methyltransferase MECOM isoform X6
         114808134 PRDM6; putative histone-lysine N-methyltransferase PRDM6
         114807912 histone-lysine N-methyltransferase PRDM9-like
         100075773 histone-lysine N-methyltransferase PRDM9
         100076427 ZNF488; zinc finger protein 488
         114814675 PRDM8; PR domain zinc finger protein 8
         100075850 PRDM12; PR domain zinc finger protein 12
         100681161 PRDM16; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase PRDM16
         100074411 SETD1B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B
         100090957 SETD1A; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A
         114816148 SETD2; histone-lysine N-methyltransferase SETD2
         100081884 SETD4; SET domain-containing protein 4 isoform X1
         100076105 SETD6; N-lysine methyltransferase SETD6
         100081674 SETD7; histone-lysine N-methyltransferase SETD7 isoform X1
         100075898 KMT5A; N-lysine methyltransferase KMT5A isoform X1
         100091318 SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X1
         100083315 SETDB2; histone-lysine N-methyltransferase SETDB2 isoform X1
         100075708 histone-lysine N-methyltransferase SETMAR
         100078649 SMYD1; histone-lysine N-methyltransferase SMYD1 isoform X1
         100079176 SMYD2; N-lysine methyltransferase SMYD2
         100082753 SMYD3; histone-lysine N-methyltransferase SMYD3 isoform X1
         100085175 SUV39H2; histone-lysine N-methyltransferase SUV39H2 isoform X3
         100084051 SUV39H1; histone-lysine N-methyltransferase SUV39H1 isoform X1
         100088070 KMT5B; histone-lysine N-methyltransferase KMT5B
         114814778 KMT5C; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase KMT5C
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354] 
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355] 
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354] 
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354] 
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354] 
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354] 
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357] 
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357] 
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371] 
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355] 
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367] 
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-] 
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-] 
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354] 
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359] 
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364] 
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-] 
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364] 
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361] 
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366] 
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355] 
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362] 
       PRMTs (protein arginine metyltransferases)
     HMT complexes
     Histone demethylases
     Polycomb repressive complex (PRC) and associated proteins
       Canonical PRC1 (PRC1.2/1.4)
       Noncanonical PRC1 (PRC1.1)
       Noncanonical PRC1 (PRC1.3/1.5)
       Noncanonical PRC1 (PRC1.6)
       PRC2.1
         100082851 EZH1; histone-lysine N-methyltransferase EZH1 isoform X1
         100073485 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
         100080634 EED; polycomb protein EED
         100080410 SUZ12; polycomb protein SUZ12
         100077895 RBBP4; histone-binding protein RBBP4
         100085544 RBBP7; histone-binding protein RBBP7
         114808911 PHF1; PHD finger protein 1
         100077121 MTF2; LOW QUALITY PROTEIN: metal-response element-binding transcription factor 2
         100681693 PHF19; PHD finger protein 19 isoform X1
         100073603 LCOR; ligand-dependent corepressor isoform X3
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K11462 EED; polycomb protein EED 
K11463 SUZ12; polycomb protein SUZ12 
K10752 RBBP4; histone-binding protein RBBP4 
K11659 RBBP7; histone-binding protein RBBP7 
K11467 PHF1; PHD finger protein 1 
K11485 MTF2; metal regulatory transcription factor 2 
K11486 PHF19; PHD finger protein 19 
K26260 LCOR; ligand-dependent corepressor 
       PRC2.2
         100082851 EZH1; histone-lysine N-methyltransferase EZH1 isoform X1
         100073485 EZH2; histone-lysine N-methyltransferase EZH2 isoform X1
         100080634 EED; polycomb protein EED
         100080410 SUZ12; polycomb protein SUZ12
         100077895 RBBP4; histone-binding protein RBBP4
         100085544 RBBP7; histone-binding protein RBBP7
         100073914 AEBP2; zinc finger protein AEBP2
         100076250 JARID2; protein Jumonji isoform X1
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356] 
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356] 
K11462 EED; polycomb protein EED 
K11463 SUZ12; polycomb protein SUZ12 
K10752 RBBP4; histone-binding protein RBBP4 
K11659 RBBP7; histone-binding protein RBBP7 
K17452 AEBP2; zinc finger protein AEBP2 
K11478 JARID2; protein Jumonji 
       PR-DUB complex
       Other PRC associated proteins
     Sir proteins
     Other histone modification proteins
   Chromosome condensation proteins
   Centromeric chromatin formation proteins
   Heterochromatin formation proteins
   Gene silencing
   Centrosome formation proteins
   Sister chromatid separation proteins
   Chromatin remodeling factors
 
 Prokaryotic type

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Last updated: April 10, 2024