KEGG Orthology (KO) - Oryzias latipes (Japanese medaka)

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     KO
 Metabolism
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ola00061]
     00062 Fatty acid elongation [PATH:ola00062]
     00071 Fatty acid degradation [PATH:ola00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ola00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:ola00100]
     00120 Primary bile acid biosynthesis [PATH:ola00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:ola00140]
     00561 Glycerolipid metabolism [PATH:ola00561]
     00564 Glycerophospholipid metabolism [PATH:ola00564]
     00565 Ether lipid metabolism [PATH:ola00565]
     00600 Sphingolipid metabolism [PATH:ola00600]
     00590 Arachidonic acid metabolism [PATH:ola00590]
       101175621 group XIIB secretory phospholipase A2-like protein
       101170929 phospholipase A2 isoform X1
       101155667 pla2g1b; phospholipase A2
       101156220 pla2g12a; group XIIA secretory phospholipase A2
       101162698 proca1; protein PROCA1
       101162393 group XIIB secretory phospholipase A2-like protein
       105355175 group 3 secretory phospholipase A2-like isoform X1
       101173712 group 3 secretory phospholipase A2
       101172400 pla2g4a; cytosolic phospholipase A2
       101156151 pla2g4c; cytosolic phospholipase A2 gamma isoform X2
       101160628 pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1
       101164444 plb1; phospholipase B1, membrane-associated
       105357244 phospholipase B1
       101157546 HRAS-like suppressor 3
       101173355 HRAS-like suppressor 3
       101169090 HRAS-like suppressor 3
       101161174 prostaglandin G/H synthase 1
       101173634 prostaglandin G/H synthase 1 isoform X1
       100359365 ptgs2; prostaglandin G/H synthase 2 precursor
       101162769 ptges; prostaglandin E synthase
       101163397 ptges2; prostaglandin E synthase 2
       101156737 ptges3; prostaglandin E synthase 3
       101161606 prostaglandin E synthase 3
       100125494 cbr1; carbonyl reductase [NADPH] 1
       101173382 fam213b; prostamide/prostaglandin F synthase
       101158441 tbxas1; thromboxane-A synthase
       101165663 lipocalin
       101158869 lcn2; neutrophil gelatinase-associated lipocalin isoform X2
       101166755 lipocalin
       101170919 ptgis; prostacyclin synthase
       101160835 alox5; arachidonate 5-lipoxygenase
       101174953 arachidonate 5-lipoxygenase
       101165738 arachidonate 12-lipoxygenase
       110014464 arachidonate 5-lipoxygenase-like
       101172215 lta4h; leukotriene A-4 hydrolase
       101170499 docosahexaenoic acid omega-hydroxylase CYP4F3
       101165938 ltc4s; leukotriene C4 synthase
       100820728 ggtl1b; gamma-glutamyl transferase-like 1b
       101161114 glutathione hydrolase 5 proenzyme isoform X2
       100820715 ggt1b; gamma-glutamyl transferase 1b
       100820716 ggtl1a; gamma-glutamyl transferase-like 1a
       100820714 ggt1a; gamma-glutamyl transferase 1a
       105357674 glutathione hydrolase 5 proenzyme
       101164048 gpx7; glutathione peroxidase 7
       101172806 gpx1; glutathione peroxidase 1
       101170806 gpx2; glutathione peroxidase 2
       101165150 gpx8; probable glutathione peroxidase 8
       101161096 glutathione peroxidase 1-like
       105354929 gpx3; glutathione peroxidase 3
       101155419 cytochrome P450 2J6
       100302452 cyp2p3; cytochrome P450 2P3
       101156965 cytochrome P450 2J6
       105353996 cytochrome P450 2J1
       101157767 cytochrome P450 2J2
       101167098 cytochrome P450 2U1
       101174158 arachidonate 15-lipoxygenase B-like
       101162978 arachidonate 15-lipoxygenase B-like
       101161284 arachidonate 8S-lipoxygenase-like
       111947934 arachidonate 8S-lipoxygenase-like
       101165239 arachidonate 8S-lipoxygenase-like
       101159319 arachidonate 8S-lipoxygenase-like
       101165945 arachidonate 15-lipoxygenase B-like isoform X1
       101157276 ephx2; bifunctional epoxide hydrolase 2
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K15729 PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
K05309 PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15717 K15717; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
K01832 TBXAS1; thromboxane-A synthase [EC:5.3.99.5]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
K17726 CYP4F2_3; leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]
K00807 LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1]
K07422 CYP2U1; cytochrome P450 family 2 subfamily U polypeptide 1
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
     00591 Linoleic acid metabolism [PATH:ola00591]
     00592 alpha-Linolenic acid metabolism [PATH:ola00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ola01040]
     01004 Lipid biosynthesis proteins [BR:ola01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system
     02022 Two-component system
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04010 MAPK signaling pathway [PATH:ola04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:ola04012]
     04310 Wnt signaling pathway [PATH:ola04310]
     04330 Notch signaling pathway [PATH:ola04330]
     04340 Hedgehog signaling pathway [PATH:ola04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:ola04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway -fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:ola04370]
       100125510 vegfa; vascular endothelial growth factor A isoform X2
       105354863 vegfb; vascular endothelial growth factor B isoform X1
       101162439 kdr; vascular endothelial growth factor receptor 2 isoform X1
       101167946 1-phosphatidylinositol 4
       101163005 plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
       101157053 plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101159746 protein kinase C alpha type isoform X2
       101160465 prkca; protein kinase C alpha type isoform X1
       105353642 prkcb; protein kinase C beta type isoform X1
       101161464 protein kinase C beta type isoform X1
       101164921 protein kinase C alpha type
       101160322 sphingosine kinase 1-like
       101160262 sphingosine kinase 2
       101167592 sphk1; sphingosine kinase 1
       101165278 hras; GTPase HRas
       101154954 GTPase HRas
       100049322 kras; GTPase KRas
       101173784 raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       101162677 map2k1; dual specificity mitogen-activated protein kinase kinase 1
       101173453 map2k2; dual specificity mitogen-activated protein kinase kinase 2
       101159747 mitogen-activated protein kinase 1
       101162905 mitogen-activated protein kinase 1
       101172400 pla2g4a; cytosolic phospholipase A2
       101156151 pla2g4c; cytosolic phospholipase A2 gamma isoform X2
       101168142 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101172250 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       101169815 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101156706 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       101162612 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101168674 calcineurin subunit B type 1-like
       101161991 ppp3r1; calcineurin subunit B type 1
       101171005 nuclear factor of activated T-cells
       101165879 nuclear factor of activated T-cells
       100359365 ptgs2; prostaglandin G/H synthase 2 precursor
       101155713 ptk2; focal adhesion kinase 1 isoform X1
       101162652 focal adhesion kinase 1 isoform X1
       101156242 shc2; SHC-transforming protein 2 isoform X1
       101171750 uncharacterized protein LOC101171750 isoform X1
       101171569 pxn; paxillin isoform X3
       101172972 cell division control protein 42 homolog isoform X1
       101164658 cell division control protein 42 homolog
       101164400 cell division control protein 42 homolog isoform X1
       101174454 cell division control protein 42 homolog
       101162042 mitogen-activated protein kinase 14A isoform X1
       101160731 mitogen-activated protein kinase 14A isoform X1
       101172944 mitogen-activated protein kinase 12
       101171243 mitogen-activated protein kinase 13
       101175696 mitogen-activated protein kinase 11
       101154993 mitogen-activated protein kinase 12 isoform X1
       101159668 mitogen-activated protein kinase 12
       101157364 mapkapk2; MAP kinase-activated protein kinase 2
       101159256 MAP kinase-activated protein kinase 2 isoform X1
       101156158 MAP kinase-activated protein kinase 2
       101166150 heat shock protein beta-1
       101166477 heat shock protein beta-1
       101173856 src; proto-oncogene tyrosine-protein kinase Src isoform X2
       101164480 proto-oncogene tyrosine-protein kinase Src isoform X4
       101161887 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       101168152 phosphatidylinositol 4
       101161626 pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       101165660 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101170665 pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma
       101156504 phosphatidylinositol 3-kinase regulatory subunit alpha
       101163728 phosphatidylinositol 3-kinase regulatory subunit gamma
       101171597 pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha
       101155144 phosphatidylinositol 3-kinase regulatory subunit gamma
       101159016 ras-related C3 botulinum toxin substrate 1
       101175028 ras-related C3 botulinum toxin substrate 1
       101158699 ras-related C3 botulinum toxin substrate 1 isoform X2
       101163549 ras-related C3 botulinum toxin substrate 2
       105354522 ras-related C3 botulinum toxin substrate 3
       101172294 akt1; RAC-alpha serine/threonine-protein kinase
       101162468 RAC-gamma serine/threonine-protein kinase
       101155451 RAC-beta serine/threonine-protein kinase
       101174244 RAC-gamma serine/threonine-protein kinase
       101174851 RAC-beta serine/threonine-protein kinase isoform X1
       101157857 casp9; caspase-9 isoform X1
       101171945 bad; bcl2-associated agonist of cell death
K05448 VEGFA; vascular endothelial growth factor A
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC-transforming protein 2
K05760 PXN; paxillin
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
     04371 Apelin signaling pathway [PATH:ola04371]
     04630 Jak-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:ola04068]
     04020 Calcium signaling pathway [PATH:ola04020]
     04070 Phosphatidylinositol signaling system [PATH:ola04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP - PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:ola04150]
     04075 Plant hormone signal transduction
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
     04640 Hematopoietic cell lineage
     04610 Complement and coagulation cascades
     04611 Platelet activation
     04620 Toll-like receptor signaling pathway [PATH:ola04620]
     04624 Toll and Imd signaling pathway
     04621 NOD-like receptor signaling pathway [PATH:ola04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ola04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ola04623]
     04625 C-type lectin receptor signaling pathway [PATH:ola04625]
       101165278 hras; GTPase HRas
       101154954 GTPase HRas
       100049322 kras; GTPase KRas
       101159234 mras; ras-related protein M-Ras
       101162668 rras2; ras-related protein R-Ras2
       101174431 ras-related protein R-Ras
       101173784 raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       101158728 putative transcription factor p65 homolog
       101157716 relb; transcription factor RelB isoform X2
       101156757 interleukin-12 subunit alpha-like
       101158636 uncharacterized protein LOC101158636
       101170029 il12b; interleukin-12 subunit beta isoform X1
       101175485 interleukin-12 subunit beta-like
       101175425 interleukin-12 subunit beta
       101169209 interleukin-1 beta
       101155127 syk; tyrosine-protein kinase SYK isoform X1
       101172160 tyrosine-protein phosphatase non-receptor type 11 isoform X2
       101156835 ptpn11; tyrosine-protein phosphatase non-receptor type 11
       101174595 mitogen-activated protein kinase kinase kinase 14
       101166422 uncharacterized protein LOC101166422 isoform X1
       101159621 inhibitor of nuclear factor kappa-B kinase subunit alpha
       101171857 inhibitor of nuclear factor kappa-B kinase subunit alpha
       101166900 nfkb2; nuclear factor NF-kappa-B p100 subunit isoform X3
       101157053 plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101155104 inositol 1
       101167700 inositol 1
       101155191 itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1
       101170574 itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
       100049421 calm3; calmodulin-3
       100049420 calm2; calmodulin-2
       100049422 calmodulin
       100049419 calmodulin-A
       101167105 calml4; calmodulin-like protein 4
       101168142 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101172250 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       101169815 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101156706 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       101162612 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       101168674 calcineurin subunit B type 1-like
       101161991 ppp3r1; calcineurin subunit B type 1
       101161493 nuclear factor of activated T-cells
       101158005 nfatc1; nuclear factor of activated T-cells, cytoplasmic 1
       101171005 nuclear factor of activated T-cells
       101165879 nuclear factor of activated T-cells
       101173291 nfatc3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1
       101172896 nuclear factor of activated T-cells
       101164749 nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1
       101167784 il10; interleukin-10
       101170128 egr2; E3 SUMO-protein ligase EGR2
       101164744 early growth response protein 2b
       100272164 egr3; early growth response protein 3
       100359365 ptgs2; prostaglandin G/H synthase 2 precursor
       101174016 prkcd; protein kinase C delta type
       101162283 protein kinase C delta type isoform X1
       101159747 mitogen-activated protein kinase 1
       101162905 mitogen-activated protein kinase 1
       101170619 apoptosis-associated speck-like protein containing a CARD
       101161579 apoptosis-associated speck-like protein containing a CARD
       101174762 caspase-1
       101156662 card9; caspase recruitment domain-containing protein 9 isoform X1
       101157889 bcl10; B-cell lymphoma/leukemia 10
       101158686 mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1
       101158194 mucosa-associated lymphoid tissue lymphoma translocation protein 1
       101171170 mucosa-associated lymphoid tissue lymphoma translocation protein 1-like isoform X1
       100049400 casp8; caspase-8
       100125536 caspase-8
       101162681 ikbkg; NF-kappa-B essential modulator isoform X1
       101170684 ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta
       101162015 NF-kappa-B inhibitor alpha
       101168165 nfkbia; NF-kappa-B inhibitor alpha
       101167764 nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1
       101172593 tumor necrosis factor-like
       101162042 mitogen-activated protein kinase 14A isoform X1
       101160731 mitogen-activated protein kinase 14A isoform X1
       101172944 mitogen-activated protein kinase 12
       101171243 mitogen-activated protein kinase 13
       101175696 mitogen-activated protein kinase 11
       101154993 mitogen-activated protein kinase 12 isoform X1
       101159668 mitogen-activated protein kinase 12
       101168799 mitogen-activated protein kinase 10 isoform X1
       101157952 mitogen-activated protein kinase 9
       101164997 mitogen-activated protein kinase 8 isoform X4
       101158978 mitogen-activated protein kinase 8 isoform X1
       101174822 transcription factor AP-1
       101160956 transcription factor AP-1
       101173011 jun; transcription factor AP-1
       101157475 cblb; E3 ubiquitin-protein ligase CBL-B isoform X1
       101168326 high affinity immunoglobulin epsilon receptor subunit gamma
       101169798 arhgef12; rho guanine nucleotide exchange factor 12 isoform X1
       101168230 rho guanine nucleotide exchange factor 12-like isoform X1
       101173444 transforming protein RhoA isoform X2
       101155194 rho-related GTP-binding protein RhoA-C
       101167618 rho-related GTP-binding protein RhoA-B
       101158607 transforming protein RhoA-like
       101160539 rho-related GTP-binding protein RhoA-C
       101164663 pak1; serine/threonine-protein kinase PAK 1
       101175586 ksr1; kinase suppressor of Ras 1 isoform X1
       101155385 plk3; serine/threonine-protein kinase PLK3
       101173856 src; proto-oncogene tyrosine-protein kinase Src isoform X2
       101164480 proto-oncogene tyrosine-protein kinase Src isoform X4
       101168283 ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1
       101173855 signal transducer and activator of transcription 1-alpha/beta isoform X1
       101158490 signal transducer and activator of transcription 1-alpha/beta isoform X1
       101154761 signal transducer and activator of transcription 1-alpha/beta isoform X1
       101173820 irf9; interferon regulatory factor 9
       100533505 il17d; interleukin-17D precursor
       101156964 cyld; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1
       101168449 ubiquitin carboxyl-terminal hydrolase CYLD
       101167576 ubiquitin carboxyl-terminal hydrolase CYLD
       101163809 ubiquitin carboxyl-terminal hydrolase CYLD
       101158722 B-cell lymphoma 3 protein
       101161792 C-C motif chemokine 17
       101157364 mapkapk2; MAP kinase-activated protein kinase 2
       101161887 pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       101168152 phosphatidylinositol 4
       101161626 pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       101165660 pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101170665 pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma
       101156504 phosphatidylinositol 3-kinase regulatory subunit alpha
       101163728 phosphatidylinositol 3-kinase regulatory subunit gamma
       101171597 pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha
       101155144 phosphatidylinositol 3-kinase regulatory subunit gamma
       101172294 akt1; RAC-alpha serine/threonine-protein kinase
       101162468 RAC-gamma serine/threonine-protein kinase
       101155451 RAC-beta serine/threonine-protein kinase
       101174244 RAC-gamma serine/threonine-protein kinase
       101174851 RAC-beta serine/threonine-protein kinase isoform X1
       101174634 mdm2; E3 ubiquitin-protein ligase Mdm2
       101163430 interferon regulatory factor 1 isoform X1
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07831 MRAS; Ras-related protein M-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07830 RRAS2; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K05406 IL12A; interleukin 12A
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05425 IL12B; interleukin 12B
K05425 IL12B; interleukin 12B
K04519 IL1B; interleukin 1 beta
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05443 IL10; interleukin 10
K12496 EGR2; early growth response protein 2
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF; tumor necrosis factor superfamily, member 2
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11220 STAT1; signal transducer and activator of transcription 1
K11220 STAT1; signal transducer and activator of transcription 1
K11220 STAT1; signal transducer and activator of transcription 1
K04693 IRF9; interferon regulatory factor 9
K05492 IL17D; interleukin 17D
K08601 CYLD; ubiquitin thioesterase [EC:3.4.19.12]
K08601 CYLD; ubiquitin thioesterase [EC:3.4.19.12]
K08601 CYLD; ubiquitin thioesterase [EC:3.4.19.12]
K08601 CYLD; ubiquitin thioesterase [EC:3.4.19.12]
K09258 BCL3; B-cell CLL/lymphoma protein 3
K21083 CCL17; C-C motif chemokine 17
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K09444 IRF1; interferon regulatory factor 1
     04650 Natural killer cell mediated cytotoxicity
     04612 Antigen processing and presentation
     04660 T cell receptor signaling pathway
     04658 Th1 and Th2 cell differentiation
     04659 Th17 cell differentiation
     04657 IL-17 signaling pathway
     04662 B cell receptor signaling pathway
     04664 Fc epsilon RI signaling pathway
     04666 Fc gamma R-mediated phagocytosis
     04670 Leukocyte transendothelial migration
     04672 Intestinal immune network for IgA production [PATH:ola04672]
     04062 Chemokine signaling pathway
     04054 Pattern recognition receptors
 
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 Human Diseases

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: May 20, 2018

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