KEGG Orthology (KO) - Oryzias latipes (Japanese medaka)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ola00061]
     00062 Fatty acid elongation [PATH:ola00062]
     00071 Fatty acid degradation [PATH:ola00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ola00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:ola00100]
     00120 Primary bile acid biosynthesis [PATH:ola00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:ola00140]
     00561 Glycerolipid metabolism [PATH:ola00561]
     00564 Glycerophospholipid metabolism [PATH:ola00564]
     00565 Ether lipid metabolism [PATH:ola00565]
     00600 Sphingolipid metabolism [PATH:ola00600]
     00590 Arachidonic acid metabolism [PATH:ola00590]
       101175621 group XIIB secretory phospholipase A2-like protein-like
       101170929 group 10 secretory phospholipase A2-like
       101155667 phospholipase A2
       101156220 group XIIA secretory phospholipase A2-like
       101162698 uncharacterized LOC101162698
       101162393 group XIIB secretory phospholipase A2-like protein-like
       101156983 group 3 secretory phospholipase A2-like
       101172400 cytosolic phospholipase A2-like
       101156151 cytosolic phospholipase A2 beta-like
       101160628 85/88 kDa calcium-independent phospholipase A2-like
       101164444 phospholipase B1
       101157546 group XVI phospholipase A1/A2-like
       101173355 group XVI phospholipase A1/A2-like
       101169090 group XVI phospholipase A1/A2-like
       101161174 prostaglandin G/H synthase 1-like
       101173634 prostaglandin G/H synthase 1-like
       100359365 ptgs2; prostaglandin-endoperoxide synthase 2 
       101162769 prostaglandin E synthase-like
       101163397 prostaglandin E synthase 2-like
       101156737 prostaglandin E synthase 3-like
       101161606 prostaglandin E synthase 3-like
       100125494 hsd20b; 20-beta-hydroxysteroid dehydrogenase
       101173382 prostamide/prostaglandin F synthase-like
       101158441 thromboxane-A synthase-like
       101165663 lipocalin-like
       101166755 lipocalin-like
       101170919 prostacyclin synthase-like
       101164120 prostacyclin synthase-like
       101160835 arachidonate 5-lipoxygenase-like
       101174953 arachidonate 5-lipoxygenase-like
       101172215 leukotriene A-4 hydrolase-like
       101170499 leukotriene-B(4) omega-hydroxylase 2-like
       101165938 leukotriene C4 synthase-like
       100820728 ggtl1b; gamma-glutamyl transferase-like 1b
       101161114 gamma-glutamyltransferase 5-like
       100820715 ggt1b; gamma-glutamyl transferase 1b
       100820716 ggtl1a; gamma-glutamyl transferase-like 1a
       100820714 ggt1a; gamma-glutamyl transferase 1a
       101164048 glutathione peroxidase 7-like
       101172806 glutathione peroxidase 1-like
       101170806 glutathione peroxidase 2-like
       101165150 probable glutathione peroxidase 8-like
       101161096 glutathione peroxidase 6-like
       101155419 cytochrome P450 2J6-like
       100302452 cyp2p3; cytochrome P450 2P3
       101156965 cytochrome P450 2J6-like
       101167098 cytochrome P450 2U1-like
       101165239 arachidonate 15-lipoxygenase B-like
       101165738 arachidonate 15-lipoxygenase B-like
       101162978 arachidonate 15-lipoxygenase B-like
       101174158 arachidonate 15-lipoxygenase B-like
       101161284 arachidonate 15-lipoxygenase B-like
       101157276 bifunctional epoxide hydrolase 2-like
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K15729 PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
K05309 PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15717 K15717; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
K01832 TBXAS1; thromboxane-A synthase [EC:5.3.99.5]
K01830 E5.3.99.2; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01830 E5.3.99.2; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
K17726 CYP4F2_3; leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194]
K00807 LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
K00432 E1.11.1.9; glutathione peroxidase [EC:1.11.1.9]
K07418 CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
K07418 CYP2J; cytochrome P450, family 2, subfamily J [EC:1.14.14.1]
K07422 CYP2U1; cytochrome P450, family 2, subfamily U, polypeptide 1
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08022 ALOX15B; arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
     00591 Linoleic acid metabolism [PATH:ola00591]
     00592 alpha-Linolenic acid metabolism [PATH:ola00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ola01040]
     01004 Lipid biosynthesis proteins [BR:ola01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
   Membrane transport
 
   Signal transduction
     02020 Two-component system
     02022 Two-component system
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04010 MAPK signaling pathway [PATH:ola04010]
     04013 MAPK signaling pathway - fly
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:ola04012]
     04310 Wnt signaling pathway [PATH:ola04310]
     04330 Notch signaling pathway [PATH:ola04330]
     04340 Hedgehog signaling pathway [PATH:ola04340]
     04350 TGF-beta signaling pathway [PATH:ola04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway -fly
     04370 VEGF signaling pathway [PATH:ola04370]
       100125510 vascular endothelial growth factor A
       101162439 vascular endothelial growth factor receptor 2-like
       101167946 1-phosphatidylinositol 4
       101163005 1-phosphatidylinositol 4
       101157053 1-phosphatidylinositol 4
       101159746 protein kinase C alpha type-like
       101161464 protein kinase C beta type-like
       101164921 protein kinase C alpha type-like
       101160465 protein kinase C alpha type-like
       101160322 sphingosine kinase 2-like
       101160262 sphingosine kinase 2-like
       101167592 sphingosine kinase 2-like
       101165278 GTPase HRas-like
       101154954 transforming protein p29-like
       100049322 Ki-Ras; c-Ki-ras-2 protooncogene
       101173784 RAF proto-oncogene serine/threonine-protein kinase-like
       101162677 dual specificity mitogen-activated protein kinase kinase 1-like
       101173453 dual specificity mitogen-activated protein kinase kinase 2-like
       101159747 mitogen-activated protein kinase 1-like
       101172400 cytosolic phospholipase A2-like
       101156151 cytosolic phospholipase A2 beta-like
       101168142 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       101172250 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       101169815 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       101156706 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       101162612 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       101168674 calcineurin subunit B type 1-like
       101161991 calcineurin subunit B type 1-like
       101171005 nuclear factor of activated T-cells
       101165879 nuclear factor of activated T-cells
       100359365 ptgs2; prostaglandin-endoperoxide synthase 2 
       101155713 focal adhesion kinase 1-like
       101175085 focal adhesion kinase 1-like
       101162652 focal adhesion kinase 1-like
       101161372 focal adhesion kinase 1-like
       101156242 SHC-transforming protein 2-like
       101171750 paxillin-like
       101171569 paxillin-like
       101172972 cell division control protein 42 homolog
       101164658 cell division control protein 42 homolog
       101164400 cell division control protein 42 homolog
       101174454 cell division control protein 42 homolog
       101162042 mitogen-activated protein kinase 14A-like
       101160731 mitogen-activated protein kinase 14A-like
       101172944 mitogen-activated protein kinase 12-like
       101171243 mitogen-activated protein kinase 13-like
       101175696 mitogen-activated protein kinase 11-like
       101154993 mitogen-activated protein kinase 12-like
       101159668 mitogen-activated protein kinase 12-like
       101165128 spindle assembly checkpoint kinase-like
       101157364 MAP kinase-activated protein kinase 2-like
       101159256 MAP kinase-activated protein kinase 3-like
       101156383 heat shock protein beta-1-like
       101166477 heat shock protein beta-1-like
       101166150 heat shock protein beta-1-like
       101173856 proto-oncogene tyrosine-protein kinase Src-like
       101164480 proto-oncogene tyrosine-protein kinase Src-like
       101161887 phosphatidylinositol 4
       101168152 phosphatidylinositol 4
       101161626 phosphatidylinositol 4
       101165660 phosphatidylinositol 4
       101173828 phosphatidylinositol 4
       101155167 phosphoinositide 3-kinase regulatory subunit 5-like
       101170665 phosphatidylinositol 3-kinase regulatory subunit gamma-like
       101156504 phosphatidylinositol 3-kinase regulatory subunit alpha-like
       101163728 phosphatidylinositol 3-kinase regulatory subunit beta-like
       101171597 phosphatidylinositol 3-kinase regulatory subunit alpha-like
       101155144 phosphatidylinositol 3-kinase regulatory subunit gamma-like
       101155772 phosphoinositide 3-kinase regulatory subunit 5-like
       101159016 ras-related C3 botulinum toxin substrate 1-like
       101175028 ras-related C3 botulinum toxin substrate 1-like
       101158768 ras-related C3 botulinum toxin substrate 1-like
       101158699 ras-related C3 botulinum toxin substrate 1-like
       101163549 ras-related C3 botulinum toxin substrate 2-like
       101172294 AKT kinase-transforming protein-like
       101162468 RAC-gamma serine/threonine-protein kinase-like
       101155451 RAC-beta serine/threonine-protein kinase-like
       101174244 RAC-gamma serine/threonine-protein kinase-like
       101174851 RAC-beta serine/threonine-protein kinase-like
       101157857 caspase-9-like
       101171945 uncharacterized LOC101171945
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K02677 CPKC; classical protein kinase C [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC- transforming protein 2
K05760 PXN; paxillin
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K04455 HSPB1; heat shock protein beta-1
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K00922 PIK3C; phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K02649 PIK3R; phosphoinositide-3-kinase, regulatory subunit
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; BCL2-antagonist of cell death
     04630 Jak-STAT signaling pathway [PATH:ola04630]
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:ola04068]
     04020 Calcium signaling pathway [PATH:ola04020]
     04070 Phosphatidylinositol signaling system [PATH:ola04070]
     04024 cAMP signaling pathway
     04022 cGMP - PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:ola04150]
     04075 Plant hormone signal transduction
 
   Signaling molecules and interaction
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases

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Last updated: December 28, 2014