KEGG Orthology (KO) - Sarcophilus harrisii (Tasmanian devil)

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     KO
 Metabolism
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:shr00061]
     00062 Fatty acid elongation [PATH:shr00062]
     00071 Fatty acid degradation [PATH:shr00071]
     00072 Synthesis and degradation of ketone bodies [PATH:shr00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:shr00100]
     00120 Primary bile acid biosynthesis [PATH:shr00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:shr00140]
       100923284 cholesterol side-chain cleavage enzyme
       100915970 steroid 17-alpha-hydroxylase/17
       100928447 STS; steryl-sulfatase isoform X1
       100933402 SULT2B1; sulfotransferase family cytosolic 2B member 1
       100915994 bile salt sulfotransferase-like
       100932451 steroid 21-hydroxylase
       100913530 HSD3B2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
       100920954 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1
       100934924 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
       100928836 SRD5A3; polyprenol reductase
       100930767 cytochrome P450 11B1
       100926677 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase
       100923255 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1
       100920521 25-hydroxycholesterol 7-alpha-hydroxylase
       100926950 sulfotransferase 1 family member D1-like
       100919259 HSD17B1; estradiol 17-beta-dehydrogenase 1
       100921563 HSD17B2; estradiol 17-beta-dehydrogenase 2
       100931687 17-beta-hydroxysteroid dehydrogenase type 6-like isoform X2
       100926227 HSD17B7; 3-keto-steroid reductase
       100914913 HSD17B8; estradiol 17-beta-dehydrogenase 8 isoform X1
       100917982 HSD17B12; very-long-chain 3-oxoacyl-CoA reductase
       100923950 testosterone 17-beta-dehydrogenase 3-like
       100927711 cytochrome P450 1A1-like
       100931571 cytochrome P450 2B6-like
       100933766 cytochrome P450 2C42-like
       100927632 cytochrome P450 2C23-like
       100928062 cytochrome P450 2C23-like
       100926939 uncharacterized protein LOC100926939
       100918011 cytochrome P450 3A4-like
       100915303 cytochrome P450 2E1
       100935353 cytochrome P450 1B1 isoform X1
       100929873 aromatase
       100926104 cholesterol 7-alpha-monooxygenase
       100914496 LOW QUALITY PROTEIN: uncharacterized protein LOC100914496
       100919527 UGT1A1; UDP-glucuronosyltransferase 1-1 isoform X6
       100915521 UDP-glucuronosyltransferase 1-6-like
       100916465 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B17-like
       100916989 UDP-glucuronosyltransferase 2B30-like
       100934159 COMT; catechol O-methyltransferase
       100933041 transmembrane O-methyltransferase-like
       100935109 HSD17B3; testosterone 17-beta-dehydrogenase 3
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B1; alcohol sulfotransferase [EC:2.8.2.2]
K01015 SULT2B1; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K07430 CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
     00561 Glycerolipid metabolism [PATH:shr00561]
     00564 Glycerophospholipid metabolism [PATH:shr00564]
     00565 Ether lipid metabolism [PATH:shr00565]
     00600 Sphingolipid metabolism [PATH:shr00600]
     00590 Arachidonic acid metabolism [PATH:shr00590]
     00591 Linoleic acid metabolism [PATH:shr00591]
     00592 alpha-Linolenic acid metabolism [PATH:shr00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:shr01040]
     01004 Lipid biosynthesis proteins [BR:shr01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:shr04911]
     04910 Insulin signaling pathway [PATH:shr04910]
     04922 Glucagon signaling pathway [PATH:shr04922]
     04923 Regulation of lipolysis in adipocyte [PATH:shr04923]
     04920 Adipocytokine signaling pathway [PATH:shr04920]
     03320 PPAR signaling pathway [PATH:shr03320]
     04912 GnRH signaling pathway [PATH:shr04912]
     04913 Ovarian Steroidogenesis [PATH:shr04913]
     04915 Estrogen signaling pathway [PATH:shr04915]
     04914 Progesterone-mediated oocyte maturation [PATH:shr04914]
     04917 Prolactin signaling pathway [PATH:shr04917]
     04921 Oxytocin signaling pathway [PATH:shr04921]
     04926 Relaxin signaling pathway [PATH:shr04926]
     04918 Thyroid hormone synthesis [PATH:shr04918]
     04919 Thyroid hormone signaling pathway [PATH:shr04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:shr04928]
     04916 Melanogenesis [PATH:shr04916]
     04924 Renin secretion [PATH:shr04924]
     04614 Renin-angiotensin system [PATH:shr04614]
     04925 Aldosterone synthesis and secretion [PATH:shr04925]
       100927259 AGTR1; type-1 angiotensin II receptor
       100916183 guanine nucleotide-binding protein G(q) subunit alpha
       100920179 GNA11; guanine nucleotide-binding protein subunit alpha-11
       100929015 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       100934049 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
       100934311 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       100922938 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
       100918532 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1
       100921270 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       100916996 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
       100913337 PRKCA; protein kinase C alpha type
       100924022 PRKCB; protein kinase C beta type
       100935225 PRKCG; protein kinase C gamma type
       100921656 PRKCE; protein kinase C epsilon type
       100918841 PRKD1; serine/threonine-protein kinase D1 isoform X2
       100913910 PRKD3; serine/threonine-protein kinase D3
       100920206 PRKD2; serine/threonine-protein kinase D2
       100913327 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       100914193 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X2
       100913697 ATF4; cyclic AMP-dependent transcription factor ATF-4
       100916355 CREB3; cyclic AMP-responsive element-binding protein 3
       100917654 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
       100923082 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4
       100926416 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       100913890 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       100922067 CREB5; cyclic AMP-responsive element-binding protein 5
       100932966 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
       100930018 ATF1; cyclic AMP-dependent transcription factor ATF-1
       100919392 DAGLB; sn1-specific diacylglycerol lipase beta
       100934733 DAGLA; sn1-specific diacylglycerol lipase alpha
       100934261 KCNK3; potassium channel subfamily K member 3
       100932240 KCNK9; potassium channel subfamily K member 9
       100928024 KCNJ5; G protein-activated inward rectifier potassium channel 4
       100922123 ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3
       100928210 ATP1A1; LOW QUALITY PROTEIN: sodium/potassium-transporting ATPase subunit alpha-1
       100914130 sodium/potassium-transporting ATPase subunit alpha-2 isoform X1
       100918637 sodium/potassium-transporting ATPase subunit alpha-2-like
       100935132 ATP1B3; sodium/potassium-transporting ATPase subunit beta-3
       100915426 ATP1B2; sodium/potassium-transporting ATPase subunit beta-2
       100915602 ATP1B1; sodium/potassium-transporting ATPase subunit beta-1
       100915285 ATP1B4; protein ATP1B4
       100921267 CACNA1G; voltage-dependent T-type calcium channel subunit alpha-1G
       100934677 CACNA1H; voltage-dependent T-type calcium channel subunit alpha-1H
       100916832 CACNA1I; voltage-dependent T-type calcium channel subunit alpha-1I
       100926503 CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
       100919750 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D
       100927554 CACNA1F; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F
       100917433 CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S
       111719559 ORAI1; calcium release-activated calcium channel protein 1
       100914803 CALML6; calmodulin-like protein 6
       100924316 calmodulin
       100920429 CALM2; calmodulin-2
       100935134 calmodulin
       100929017 CALM1; calmodulin-1
       105750699 calmodulin-A
       100925046 CALML4; calmodulin-like protein 4
       100929212 CAMK1; calcium/calmodulin-dependent protein kinase type 1
       100922469 CAMK1G; calcium/calmodulin-dependent protein kinase type 1G
       100927184 CAMK1D; calcium/calmodulin-dependent protein kinase type 1D
       100916233 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       100934917 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
       100918427 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       100915634 calcium/calmodulin-dependent protein kinase type II subunit delta
       100913975 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
       100920792 CAMK4; calcium/calmodulin-dependent protein kinase type IV
       100922398 plasma membrane calcium-transporting ATPase 4 isoform X2
       100926374 ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1
       100914244 ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X4
       100921801 ATP2B1; plasma membrane calcium-transporting ATPase 1
       100930479 LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 1-like
       100926393 LIPE; hormone-sensitive lipase
       100923750 LDLR; low-density lipoprotein receptor isoform X1
       100923937 SCARB1; scavenger receptor class B member 1
       100925922 POMC; pro-opiomelanocortin
       100915134 MC2R; adrenocorticotropic hormone receptor
       100930666 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       100922193 ADCY1; adenylate cyclase type 1
       100922434 ADCY2; adenylate cyclase type 2
       100925657 ADCY3; adenylate cyclase type 3
       111718832 adenylate cyclase type 3-like
       100920243 ADCY4; adenylate cyclase type 4
       100929558 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100932634 ADCY6; adenylate cyclase type 6 isoform X3
       100929278 ADCY7; adenylate cyclase type 7 isoform X1
       100923926 ADCY8; adenylate cyclase type 8
       100926025 ADCY9; adenylate cyclase type 9 isoform X2
       100929360 cAMP-dependent protein kinase catalytic subunit alpha
       100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2
       100913731 cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1
       100913378 STAR; steroidogenic acute regulatory protein, mitochondrial
       100927247 NR4A2; nuclear receptor subfamily 4 group A member 2 isoform X1
       100931514 NR4A1; nuclear receptor subfamily 4 group A member 1
       100923284 cholesterol side-chain cleavage enzyme
       100913530 HSD3B2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
       100932451 steroid 21-hydroxylase
       100921526 NPR1; atrial natriuretic peptide receptor 1
       100926997 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K09053 ATF1; activating transcription factor 1
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
K04914 KCNK3; potassium channel subfamily K member 3
K04919 KCNK9; potassium channel subfamily K member 9
K04999 KCNJ5; potassium inwardly-rectifying channel subfamily J member 5
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01539 ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9]
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K01540 ATP1B; sodium/potassium-transporting ATPase subunit beta
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K16056 ORAI1; calcium release-activated calcium channel protein 1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K05850 ATP2B; Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
     04927 Cortisol synthesis and secretion [PATH:shr04927]
       100925922 POMC; pro-opiomelanocortin
       100915134 MC2R; adrenocorticotropic hormone receptor
       105749807 MRAP; melanocortin-2 receptor accessory protein
       100930666 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       100922193 ADCY1; adenylate cyclase type 1
       100922434 ADCY2; adenylate cyclase type 2
       100925657 ADCY3; adenylate cyclase type 3
       111718832 adenylate cyclase type 3-like
       100920243 ADCY4; adenylate cyclase type 4
       100929558 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100932634 ADCY6; adenylate cyclase type 6 isoform X3
       100929278 ADCY7; adenylate cyclase type 7 isoform X1
       100923926 ADCY8; adenylate cyclase type 8
       100926025 ADCY9; adenylate cyclase type 9 isoform X2
       100932935 PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
       100934646 PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
       100929360 cAMP-dependent protein kinase catalytic subunit alpha
       100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2
       100913731 cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1
       100920164 NR5A1; steroidogenic factor 1
       100931514 NR4A1; nuclear receptor subfamily 4 group A member 1
       100930024 SP1; transcription factor Sp1 isoform X1
       100928718 PBX1; pre-B-cell leukemia transcription factor 1 isoform X1
       100913327 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       100914193 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X2
       100913697 ATF4; cyclic AMP-dependent transcription factor ATF-4
       100916355 CREB3; cyclic AMP-responsive element-binding protein 3
       100917654 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
       100923082 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4
       100926416 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       100913890 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       100922067 CREB5; cyclic AMP-responsive element-binding protein 5
       100932966 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
       100930767 cytochrome P450 11B1
       100915970 steroid 17-alpha-hydroxylase/17
       100913378 STAR; steroidogenic acute regulatory protein, mitochondrial
       100929735 NCEH1; neutral cholesterol ester hydrolase 1
       100927259 AGTR1; type-1 angiotensin II receptor
       100916183 guanine nucleotide-binding protein G(q) subunit alpha
       100920179 GNA11; guanine nucleotide-binding protein subunit alpha-11
       100929015 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       100934049 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
       100934311 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       100922938 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
       100918532 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1
       100921270 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       100916996 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
       100935232 KCNK2; potassium channel subfamily K member 2
       100921267 CACNA1G; voltage-dependent T-type calcium channel subunit alpha-1G
       100934677 CACNA1H; voltage-dependent T-type calcium channel subunit alpha-1H
       100916832 CACNA1I; voltage-dependent T-type calcium channel subunit alpha-1I
       100926503 CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
       100919750 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D
       100927554 CACNA1F; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F
       100917433 CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S
       111719559 ORAI1; calcium release-activated calcium channel protein 1
       100935331 KCNA4; potassium voltage-gated channel subfamily A member 4
       100934261 KCNK3; potassium channel subfamily K member 3
       100923750 LDLR; low-density lipoprotein receptor isoform X1
       100923937 SCARB1; scavenger receptor class B member 1
       100923284 cholesterol side-chain cleavage enzyme
       100913530 HSD3B2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
       100932451 steroid 21-hydroxylase
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K22398 MRAP; melanocortin 2 receptor accessory protein
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08560 NR5A1; steroidogenic factor 1
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K04684 SP1; transcription factor Sp1
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K14349 NCEH1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04913 KCNK2; potassium channel subfamily K member 2
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04877 KCNA4; potassium voltage-gated channel Shaker-related subfamily A member 4
K04914 KCNK3; potassium channel subfamily K member 3
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
 
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 Human Diseases
 
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   Endocrine and metabolic diseases
     04930 Type II diabetes mellitus [PATH:shr04930]
     04940 Type I diabetes mellitus [PATH:shr04940]
     04950 Maturity onset diabetes of the young [PATH:shr04950]
     04932 Non-alcoholic fatty liver disease (NAFLD) [PATH:shr04932]
     04931 Insulin resistance [PATH:shr04931]
     04933 AGE-RAGE signaling pathway in diabetic complications [PATH:shr04933]
     04934 Cushing's syndrome [PATH:shr04934]
       100915564 CRH; corticoliberin
       100919690 CRHR1; corticotropin-releasing factor receptor 1
       100932343 CRHR2; corticotropin-releasing factor receptor 2
       100930666 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       100922193 ADCY1; adenylate cyclase type 1
       100922434 ADCY2; adenylate cyclase type 2
       100925657 ADCY3; adenylate cyclase type 3
       111718832 adenylate cyclase type 3-like
       100920243 ADCY4; adenylate cyclase type 4
       100929558 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100932634 ADCY6; adenylate cyclase type 6 isoform X3
       100929278 ADCY7; adenylate cyclase type 7 isoform X1
       100923926 ADCY8; adenylate cyclase type 8
       100926025 ADCY9; adenylate cyclase type 9 isoform X2
       100929360 cAMP-dependent protein kinase catalytic subunit alpha
       100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2
       100913731 cAMP-dependent protein kinase catalytic subunit alpha-like isoform X1
       100913327 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       100914193 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X2
       100913697 ATF4; cyclic AMP-dependent transcription factor ATF-4
       100916355 CREB3; cyclic AMP-responsive element-binding protein 3
       100917654 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
       100923082 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4
       100926416 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       100913890 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       100922067 CREB5; cyclic AMP-responsive element-binding protein 5
       100932966 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
       105750976 MEN1; menin isoform X1
       100917906 ASH2L; set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1
       100931144 RBBP5; retinoblastoma-binding protein 5 isoform X1
       100921909 WDR5; WD repeat-containing protein 5
       100930938 WD repeat-containing protein 5-like
       100924557 KMT2A; histone-lysine N-methyltransferase 2A
       100928575 KMT2D; histone-lysine N-methyltransferase 2D
       100927420 CDKN2C; cyclin-dependent kinase 4 inhibitor C
       100932899 CDK4; cyclin-dependent kinase 4
       100924154 CDK6; cyclin-dependent kinase 6
       100917462 CCND1; G1/S-specific cyclin-D1
       100914196 RB1; retinoblastoma-associated protein
       100921594 E2F2; transcription factor E2F2
       100934669 E2F3; transcription factor E2F3
       100931990 RASD1; dexamethasone-induced Ras-related protein 1
       100914706 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       100928725 guanine nucleotide-binding protein G(k) subunit alpha
       100916740 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       100933338 AHR; aryl hydrocarbon receptor
       100919416 AIPL1; aryl-hydrocarbon-interacting protein-like 1
       100928585 AIP; AH receptor-interacting protein
       100927007 aryl-hydrocarbon-interacting protein-like 1
       100917700 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
       100928055 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100925631 CDK2; cyclin-dependent kinase 2 isoform X3
       100920942 CCNE1; G1/S-specific cyclin-E1
       100924454 CCNE2; G1/S-specific cyclin-E2 isoform X1
       100926666 CDKN1A; cyclin-dependent kinase inhibitor 1
       100926503 CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
       100919750 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D
       100927554 CACNA1F; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F
       100917433 CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S
       100916233 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       100934917 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
       100918427 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       100915634 calcium/calmodulin-dependent protein kinase type II subunit delta
       100913975 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
       100935403 RAP1A; ras-related protein Rap-1A isoform X2
       100920135 RAP1B; ras-related protein Rap-1b
       100934801 BRAF; serine/threonine-protein kinase B-raf isoform X1
       100921899 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100934929 dual specificity mitogen-activated protein kinase kinase 1
       100917396 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100934330 MAPK3; mitogen-activated protein kinase 3
       100913231 MAPK1; mitogen-activated protein kinase 1
       100931514 NR4A1; nuclear receptor subfamily 4 group A member 1
       100914017 EGFR; epidermal growth factor receptor isoform X1
       100929013 USP8; ubiquitin carboxyl-terminal hydrolase 8
       100925922 POMC; pro-opiomelanocortin
       100915134 MC2R; adrenocorticotropic hormone receptor
       105749807 MRAP; melanocortin-2 receptor accessory protein
       100932935 PDE8B; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
       100934646 PDE8A; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
       100919404 dual 3'
       105749857 dual 3'
       100920164 NR5A1; steroidogenic factor 1
       100930024 SP1; transcription factor Sp1 isoform X1
       100928718 PBX1; pre-B-cell leukemia transcription factor 1 isoform X1
       100930767 cytochrome P450 11B1
       100915970 steroid 17-alpha-hydroxylase/17
       100913378 STAR; steroidogenic acute regulatory protein, mitochondrial
       100929735 NCEH1; neutral cholesterol ester hydrolase 1
       100921408 ARMC5; armadillo repeat-containing protein 5
       100927259 AGTR1; type-1 angiotensin II receptor
       100916183 guanine nucleotide-binding protein G(q) subunit alpha
       100920179 GNA11; guanine nucleotide-binding protein subunit alpha-11
       100929015 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       100934049 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
       100934311 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       100922938 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
       100918532 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1
       100921270 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       100916996 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
       100935232 KCNK2; potassium channel subfamily K member 2
       100921267 CACNA1G; voltage-dependent T-type calcium channel subunit alpha-1G
       100934677 CACNA1H; voltage-dependent T-type calcium channel subunit alpha-1H
       100916832 CACNA1I; voltage-dependent T-type calcium channel subunit alpha-1I
       111719559 ORAI1; calcium release-activated calcium channel protein 1
       100935331 KCNA4; potassium voltage-gated channel subfamily A member 4
       100934261 KCNK3; potassium channel subfamily K member 3
       100923750 LDLR; low-density lipoprotein receptor isoform X1
       100923937 SCARB1; scavenger receptor class B member 1
       100923284 cholesterol side-chain cleavage enzyme
       100913530 HSD3B2; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
       100932451 steroid 21-hydroxylase
       100915344 FH; fumarate hydratase, mitochondrial
       100928059 WNT1; proto-oncogene Wnt-1
       100918306 WNT2; protein Wnt-2
       100918389 WNT2B; protein Wnt-2b
       100914628 WNT3A; protein Wnt-3a
       100935307 WNT3; proto-oncogene Wnt-3
       100925510 WNT4; protein Wnt-4
       100917926 WNT5A; protein Wnt-5a
       100924415 WNT5B; protein Wnt-5b
       100933826 WNT6; protein Wnt-6
       100931119 WNT7A; protein Wnt-7a
       100925362 WNT7B; protein Wnt-7b
       100923381 WNT8A; protein Wnt-8a
       100934290 protein Wnt-8b-like
       100914365 WNT9A; protein Wnt-9a isoform X1
       100919162 WNT9B; LOW QUALITY PROTEIN: protein Wnt-9b
       100917765 WNT10A; protein Wnt-10a
       100932979 WNT10B; protein Wnt-10b
       100913767 WNT11; protein Wnt-11
       100921973 WNT16; protein Wnt-16
       100921540 FZD1; frizzled-1
       100923425 FZD7; frizzled-7
       100932536 FZD2; frizzled-2
       100919821 FZD3; frizzled-3
       100919498 FZD4; frizzled-4
       100916636 FZD5; frizzled-5
       111721152 FZD8; frizzled-8
       100919476 FZD6; frizzled-6
       100914963 FZD10; frizzled-10
       100931932 DVL2; segment polarity protein dishevelled homolog DVL-2
       100932600 DVL1; segment polarity protein dishevelled homolog DVL-1
       100932119 DVL3; segment polarity protein dishevelled homolog DVL-3
       100920192 GSK3B; glycogen synthase kinase-3 beta
       100923576 AXIN1; axin-1 isoform X2
       100933740 AXIN2; axin-2 isoform X1
       100930636 CTNNB1; catenin beta-1
       100925931 APC2; adenomatous polyposis coli protein 2
       100915224 adenomatous polyposis coli protein
       100914543 adenomatous polyposis coli protein
       100930141 TCF7; transcription factor 7
       100922609 TCF7L1; LOW QUALITY PROTEIN: transcription factor 7-like 1
       100922675 TCF7L2; transcription factor 7-like 2 isoform X10
       100934638 lymphoid enhancer-binding factor 1
       100932903 lymphoid enhancer-binding factor 1-like
K05256 CRH; corticotropin-releasing hormone
K04578 CRHR1; corticotropin releasing hormone receptor 1
K04579 CRHR2; corticotropin releasing hormone receptor 2
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K14970 MEN1; menin
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14961 RBBP5; COMPASS component SWD1
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K09186 MLL1; histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43]
K09187 MLL2; histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K09093 AHR; aryl hydrocarbon receptor
K17767 AIP; AH receptor-interacting protein
K17767 AIP; AH receptor-interacting protein
K17767 AIP; AH receptor-interacting protein
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
K05228 POMC; proopiomelanocortin
K04200 MC2R; melanocortin 2 receptor
K22398 MRAP; melanocortin 2 receptor accessory protein
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K08560 NR5A1; steroidogenic factor 1
K04684 SP1; transcription factor Sp1
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K14349 NCEH1; neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
K22499 ARMC5; armadillo repeat-containing protein 5
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04913 KCNK2; potassium channel subfamily K member 2
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K16056 ORAI1; calcium release-activated calcium channel protein 1
K04877 KCNA4; potassium voltage-gated channel Shaker-related subfamily A member 4
K04914 KCNK3; potassium channel subfamily K member 3
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04492 LEF1; lymphoid enhancer-binding factor 1
 
   Infectious diseases
 
   Drug resistance

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 21, 2018