KEGG Orthology (KO) - Sarcophilus harrisii (Tasmanian devil)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:shr00061]
     00062 Fatty acid elongation [PATH:shr00062]
     00071 Fatty acid degradation [PATH:shr00071]
     00072 Synthesis and degradation of ketone bodies [PATH:shr00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:shr00100]
     00120 Primary bile acid biosynthesis [PATH:shr00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:shr00140]
       100923284 cholesterol side-chain cleavage enzyme
       100915970 steroid 17-alpha-hydroxylase/17
       100928447 STS; steroid sulfatase (microsomal), isozyme S
       100933402 SULT2B1; sulfotransferase family, cytosolic, 2B, member 1
       100932451 steroid 21-hydroxylase
       100913530 HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
       100920954 SRD5A1; steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
       100934924 SRD5A2; steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
       100928836 SRD5A3; steroid 5 alpha-reductase 3
       100930767 cytochrome P450 11B1
       100926677 AKR1D1; aldo-keto reductase family 1, member D1
       100923255 HSD11B1; hydroxysteroid (11-beta) dehydrogenase 1
       105749110 HSD11B2; hydroxysteroid (11-beta) dehydrogenase 2
       100920521 25-hydroxycholesterol 7-alpha-hydroxylase
       100926950 sulfotransferase 1 family member D1-like
       100919259 HSD17B1; hydroxysteroid (17-beta) dehydrogenase 1
       100921563 HSD17B2; hydroxysteroid (17-beta) dehydrogenase 2
       100931687 17-beta-hydroxysteroid dehydrogenase type 6-like
       100926227 HSD17B7; hydroxysteroid (17-beta) dehydrogenase 7
       100914913 HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8
       100917982 HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12
       100927711 cytochrome P450 1A1-like
       100931571 cytochrome P450 2B4-like
       100933766 cytochrome P450 2C42-like
       100915447 cytochrome P450 2C19-like
       100927632 cytochrome P450 2C23-like
       100928062 cytochrome P450 2C23-like
       100918011 cytochrome P450 3A4-like
       100915303 cytochrome P450 2E1
       100935353 cytochrome P450 1B1
       100929873 aromatase
       100926104 cholesterol 7-alpha-monooxygenase
       100914496 uncharacterized LOC100914496
       100919527 UGT1A1; UDP glucuronosyltransferase 1 family, polypeptide A1
       100915521 UDP-glucuronosyltransferase 1-6-like
       100924430 UDP-glucuronosyltransferase 2B31-like
       100916465 UDP-glucuronosyltransferase 2B17-like
       100934159 COMT; catechol-O-methyltransferase
       100935109 HSD17B3; hydroxysteroid (17-beta) dehydrogenase 3
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone aldolase [EC:1.14.14.19 4.1.2.30]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B1; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
K07430 CYP7B; oxysterol 7-alpha-hydroxylase [EC:1.14.13.100]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K07408 CYP1A1; cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450, family 2, subfamily B [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450, family 2, subfamily C [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450, family 3, subfamily A [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-]
K07410 CYP1B1; cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
     00561 Glycerolipid metabolism [PATH:shr00561]
     00564 Glycerophospholipid metabolism [PATH:shr00564]
     00565 Ether lipid metabolism [PATH:shr00565]
     00600 Sphingolipid metabolism [PATH:shr00600]
     00590 Arachidonic acid metabolism [PATH:shr00590]
     00591 Linoleic acid metabolism [PATH:shr00591]
     00592 alpha-Linolenic acid metabolism [PATH:shr00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:shr01040]
     01004 Lipid biosynthesis proteins [BR:shr01004]
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
   Immune system
 
   Endocrine system
     04911 Insulin secretion [PATH:shr04911]
     04910 Insulin signaling pathway [PATH:shr04910]
     04922 Glucagon signaling pathway [PATH:shr04922]
     04923 Regulation of lipolysis in adipocyte [PATH:shr04923]
     04920 Adipocytokine signaling pathway [PATH:shr04920]
     03320 PPAR signaling pathway [PATH:shr03320]
     04912 GnRH signaling pathway [PATH:shr04912]
     04913 Ovarian Steroidogenesis [PATH:shr04913]
     04915 Estrogen signaling pathway [PATH:shr04915]
     04914 Progesterone-mediated oocyte maturation [PATH:shr04914]
     04917 Prolactin signaling pathway [PATH:shr04917]
     04921 Oxytocin signaling pathway [PATH:shr04921]
     04918 Thyroid hormone synthesis [PATH:shr04918]
     04919 Thyroid hormone signaling pathway [PATH:shr04919]
     04916 Melanogenesis [PATH:shr04916]
     04924 Renin secretion [PATH:shr04924]
     04614 Renin-angiotensin system [PATH:shr04614]
     04925 Aldosterone synthesis and secretion [PATH:shr04925]
       100927259 AGTR1; angiotensin II receptor, type 1
       100916183 GNAQ; guanine nucleotide binding protein (G protein), q polypeptide
       100920179 GNA11; guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
       100929015 PLCB2; phospholipase C, beta 2
       100934049 PLCB4; phospholipase C, beta 4
       100934311 PLCB1; phospholipase C, beta 1 (phosphoinositide-specific)
       100922938 PLCB3; phospholipase C, beta 3 (phosphatidylinositol-specific)
       100918532 ITPR1; inositol 1,4,5-trisphosphate receptor, type 1
       100921270 ITPR2; inositol 1,4,5-trisphosphate receptor, type 2
       100916996 ITPR3; inositol 1,4,5-trisphosphate receptor, type 3
       100913337 PRKCA; protein kinase C, alpha
       100924022 PRKCB; protein kinase C, beta
       100935225 PRKCG; protein kinase C, gamma
       100921656 PRKCE; protein kinase C, epsilon
       100918841 PRKD1; protein kinase D1
       100913910 PRKD3; protein kinase D3
       100920206 PRKD2; protein kinase D2
       100913327 CREB1; cAMP responsive element binding protein 1
       100914193 ATF2; activating transcription factor 2
       100913697 ATF4; activating transcription factor 4
       100916355 CREB3; cAMP responsive element binding protein 3
       100917654 CREB3L3; cAMP responsive element binding protein 3-like 3
       100923082 CREB3L4; cAMP responsive element binding protein 3-like 4
       100926416 CREB3L2; cAMP responsive element binding protein 3-like 2
       100913890 CREB3L1; cAMP responsive element binding protein 3-like 1
       100922067 CREB5; cAMP responsive element binding protein 5
       100932966 ATF6B; activating transcription factor 6 beta
       100930018 ATF1; activating transcription factor 1
       100919392 DAGLB; diacylglycerol lipase, beta
       100934733 DAGLA; diacylglycerol lipase, alpha
       100934261 KCNK3; potassium channel, two pore domain subfamily K, member 3
       100932240 KCNK9; potassium channel, two pore domain subfamily K, member 9
       100921267 CACNA1G; calcium channel, voltage-dependent, T type, alpha 1G subunit
       100934677 CACNA1H; calcium channel, voltage-dependent, T type, alpha 1H subunit
       100916832 CACNA1I; calcium channel, voltage-dependent, T type, alpha 1I subunit
       100926503 CACNA1C; calcium channel, voltage-dependent, L type, alpha 1C subunit
       100919750 CACNA1D; calcium channel, voltage-dependent, L type, alpha 1D subunit
       100927554 CACNA1F; calcium channel, voltage-dependent, L type, alpha 1F subunit
       100917433 CACNA1S; calcium channel, voltage-dependent, L type, alpha 1S subunit
       100914803 CALML6; calmodulin-like 6
       100924316 calmodulin
       100920429 CALM2; calmodulin 2 (phosphorylase kinase, delta)
       100935134 CALM3; calmodulin 3 (phosphorylase kinase, delta)
       100929017 CALM1; calmodulin 1 (phosphorylase kinase, delta)
       100925278 calmodulin-like
       105750699 CALML3; calmodulin-like 3
       100929212 CAMK1; calcium/calmodulin-dependent protein kinase I
       100922469 CAMK1G; calcium/calmodulin-dependent protein kinase IG
       100927184 CAMK1D; calcium/calmodulin-dependent protein kinase ID
       100916233 CAMK2G; calcium/calmodulin-dependent protein kinase II gamma
       100934917 CAMK2A; calcium/calmodulin-dependent protein kinase II alpha
       100918427 CAMK2B; calcium/calmodulin-dependent protein kinase II beta
       100915634 calcium/calmodulin-dependent protein kinase type II subunit delta
       100913975 CAMK2D; calcium/calmodulin-dependent protein kinase II delta
       100920792 CAMK4; calcium/calmodulin-dependent protein kinase IV
       100926393 LIPE; lipase, hormone-sensitive
       100923750 LDLR; low density lipoprotein receptor
       100923937 SCARB1; scavenger receptor class B, member 1
       100915134 MC2R; melanocortin 2 receptor (adrenocorticotropic hormone)
       100930666 GNAS; GNAS complex locus
       100922193 ADCY1; adenylate cyclase 1 (brain)
       100922434 ADCY2; adenylate cyclase 2 (brain)
       100925657 ADCY3; adenylate cyclase 3
       100920243 ADCY4; adenylate cyclase 4
       100929558 ADCY5; adenylate cyclase 5
       100932634 ADCY6; adenylate cyclase 6
       100929278 ADCY7; adenylate cyclase 7
       100923926 ADCY8; adenylate cyclase 8 (brain)
       100926025 ADCY9; adenylate cyclase 9
       100915481 PRKACA; protein kinase, cAMP-dependent, catalytic, alpha
       100934183 PRKACB; protein kinase, cAMP-dependent, catalytic, beta
       100913378 STAR; steroidogenic acute regulatory protein
       100927247 NR4A2; nuclear receptor subfamily 4, group A, member 2
       100931514 NR4A1; nuclear receptor subfamily 4, group A, member 1
       100923284 cholesterol side-chain cleavage enzyme
       100913530 HSD3B2; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
       100932451 steroid 21-hydroxylase
       100921526 NPR1; natriuretic peptide receptor 1
       100926997 PDE2A; phosphodiesterase 2A, cGMP-stimulated
K04166 AGTR1; angiotensin II receptor type 1
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K06070 PKD; protein kinase D [EC:2.7.11.13]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K09053 ATF1; activating transcription factor 1
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
K13806 DAGL; sn1-specific diacylglycerol lipase [EC:3.1.1.-]
K04914 KCNK3; potassium channel subfamily K member 3
K04919 KCNK9; potassium channel subfamily K member 9
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04855 CACNA1H; voltage-dependent calcium channel T type alpha-1H
K04856 CACNA1I; voltage-dependent calcium channel T type alpha-1I
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K12473 LDLR; low-density lipoprotein receptor
K13885 SCARB1; scavenger receptor class B, member 1
K04200 MC2R; melanocortin 2 receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K16931 STAR; steroidogenic acute regulatory protein, mitochondrial
K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
K04465 NR4A1; nuclear receptor subfamily 4 group A member 1
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00070 HSD3B; 3beta-hydroxy-delta5-steroid dehydrogenase / steroid delta-isomerase [EC:1.1.1.145 5.3.3.1]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
 
   Circulatory system
 
   Digestive system
 
   Excretory system
 
   Nervous system
 
   Sensory system
 
   Development
 
   Aging
 
   Environmental adaptation
 
 Human Diseases

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Last updated: May 3, 2016