KEGG Orthology (KO) - Sus scrofa (pig)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
     00410 beta-Alanine metabolism [PATH:ssc00410]
     00430 Taurine and hypotaurine metabolism [PATH:ssc00430]
     00440 Phosphonate and phosphinate metabolism [PATH:ssc00440]
     00450 Selenocompound metabolism [PATH:ssc00450]
     00460 Cyanoamino acid metabolism
     00471 D-Glutamine and D-glutamate metabolism [PATH:ssc00471]
     00472 D-Arginine and D-ornithine metabolism [PATH:ssc00472]
     00473 D-Alanine metabolism
     00480 Glutathione metabolism [PATH:ssc00480]
       100519401 GGT7; gamma-glutamyltransferase 7
       100523568 GGT6; gamma-glutamyltransferase 6
       397095 GGT1; gamma-glutamyltransferase 1
       100157523 GGT5; gamma-glutamyltransferase 5
       100624445 gamma-glutamylcyclotransferase-like
       100515137 5-oxoprolinase-like
       100517090 OPLAH; 5-oxoprolinase
       100522018 GCLC; glutamate-cysteine ligase catalytic subunit
       100153977 GCLM; glutamate-cysteine ligase modifier subunit
       100152660 GSS; glutathione synthetase
       106504107 cytosol aminopeptidase
       397520 ANPEP; alanyl aminopeptidase, membrane
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase
       100516363 NAT8; N-acetyltransferase 8
       396625 GSR; glutathione reductase
       397603 IDH2; isocitrate dehydrogenase (NADP(+)) 2, mitochondrial
       102166364 IDH1; isocitrate dehydrogenase (NADP(+)) 1, cytosolic
       397546 PGD; phosphogluconate dehydrogenase
       100515002 glucose-6-phosphate 1-dehydrogenase X-like
       100622986 G6PD; glucose-6-phosphate 1-dehydrogenase
       100517534 TXNDC12; thioredoxin domain containing 12
       396920 GPX5; glutathione peroxidase 5
       397403 GPX1; glutathione peroxidase 1
       767625 GPX2; glutathione peroxidase 2
       396598 GPX3; glutathione peroxidase 3
       100154091 GPX6; glutathione peroxidase 6
       100621417 GPX7; glutathione peroxidase 7
       100519691 GPX8; glutathione peroxidase 8 (putative)
       399537 GPX4; glutathione peroxidase 4
       414408 ODC1; ornithine decarboxylase 1
       100520618 ornithine decarboxylase-like
       414385 SRM; spermidine synthase
       100153052 SMS; spermine synthase
       100525117 RRM1; ribonucleoside-diphosphate reductase large subunit
       102166900 RRM1; ribonucleoside-diphosphate reductase large subunit
       100157205 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       100316853 RRM2; ribonucleotide reductase regulatory subunit M2
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00682 GGCT; gamma-glutamylcyclotransferase [EC:2.3.2.4]
K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205 GCLM; glutamate--cysteine ligase regulatory subunit
K21456 GSS; glutathione synthase [EC:6.3.2.3]
K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11140 ANPEP; aminopeptidase N [EC:3.4.11.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K20838 NAT8; N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-]
K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K05360 TXNDC12; protein-disulfide reductase (glutathione) [EC:1.8.4.2]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K05361 GPX4; phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K00797 speE; spermidine synthase [EC:2.5.1.16]
K00802 SMS; spermine synthase [EC:2.5.1.22]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
     00362 Benzoate degradation
     00627 Aminobenzoate degradation
     00364 Fluorobenzoate degradation
     00625 Chloroalkane and chloroalkene degradation
     00361 Chlorocyclohexane and chlorobenzene degradation
     00623 Toluene degradation
     00622 Xylene degradation
     00633 Nitrotoluene degradation
     00642 Ethylbenzene degradation
     00643 Styrene degradation
     00791 Atrazine degradation
     00930 Caprolactam degradation
     00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
     00363 Bisphenol degradation
     00621 Dioxin degradation
     00626 Naphthalene degradation
     00624 Polycyclic aromatic hydrocarbon degradation
     00365 Furfural degradation
     00984 Steroid degradation
     00980 Metabolism of xenobiotics by cytochrome P450 [PATH:ssc00980]
       403103 CYP1A1; cytochrome P450 1A1
       100625479 cytochrome P450 1B1-like
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase
       397639 EPHX1; epoxide hydrolase 1
       641359 SULT2A1; sulfotransferase family 2A member 1
       100152910 CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2
       403216 CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1
       100523190 cytochrome P450 2F1-like
       106510546 CYP2S1; cytochrome P450 2S1
       397337 DHDH; dihydrodiol dehydrogenase
       397480 HSD11B1; hydroxysteroid 11-beta dehydrogenase 1
       397143 CBR1; carbonyl reductase 1
       100622246 CBR3; carbonyl reductase [NADPH] 1
       396780 CBR2; carbonyl reductase 2
       100512990 CBR3; carbonyl reductase 3
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6
       100511841 UGT1A10; UDP-glucuronosyltransferase 1-10
       100515394 UDP-glucuronosyltransferase 2C1-like
       100515741 UDP-glucuronosyltransferase 2B4-like
       100516628 UDP-glucuronosyltransferase 2B18-like
       100624700 UDP-glucuronosyltransferase 2C1-like
       100738495 UDP-glucuronosyltransferase 2B31-like
       100624788 UGT2A1; UDP-glucuronosyltransferase 2A1
       100623255 UDP-glucuronosyltransferase 2B31-like
       100513872 UGT2B17; UDP-glucuronosyltransferase 2B17
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31
       100511479 UGT1A3; UDP-glucuronosyltransferase 1-1
       100511331 AKR7A2; aldo-keto reductase family 7 member A2
       100155494 aldehyde dehydrogenase family 1 member A3
       100526075 ALDH3A1; aldehyde dehydrogenase 3 family member A1
       100739347 ALDH3B1; aldehyde dehydrogenase 3 family member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like
       106504111 aldehyde dehydrogenase family 1 member A3-like
       100512795 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07420 CYP2S1; cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]
K00078 DHDH; dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00081 CBR2; carbonyl reductase 2 [EC:1.1.1.184]
K00084 CBR3; carbonyl reductase 3 [EC:1.1.1.184]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K15303 AKR7; aflatoxin B1 aldehyde reductase
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
     00982 Drug metabolism - cytochrome P450 [PATH:ssc00982]
       397132 FMO1; flavin containing monooxygenase 1
       100152950 FMO5; flavin containing monooxygenase 5
       100523562 FMO3; flavin containing monooxygenase 3
       100525884 FMO2; flavin containing monooxygenase 2
       100621718 FMO4; dimethylaniline monooxygenase [N-oxide-forming] 4
       100151788 dimethylaniline monooxygenase [N-oxide-forming] 5-like
       100523745 putative dimethylaniline monooxygenase [N-oxide-forming] 6
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase
       100512795 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
       100155494 aldehyde dehydrogenase family 1 member A3
       100526075 ALDH3A1; aldehyde dehydrogenase 3 family member A1
       100739347 ALDH3B1; aldehyde dehydrogenase 3 family member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like
       106504111 aldehyde dehydrogenase family 1 member A3-like
       414424 MAOA; monoamine oxidase A
       414909 MAOB; monoamine oxidase B
       100523701 AOX1; aldehyde oxidase 1
       100525616 AOX2; aldehyde oxidase 2
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6
       100511841 UGT1A10; UDP-glucuronosyltransferase 1-10
       100515394 UDP-glucuronosyltransferase 2C1-like
       100515741 UDP-glucuronosyltransferase 2B4-like
       100516628 UDP-glucuronosyltransferase 2B18-like
       100624700 UDP-glucuronosyltransferase 2C1-like
       100738495 UDP-glucuronosyltransferase 2B31-like
       100624788 UGT2A1; UDP-glucuronosyltransferase 2A1
       100623255 UDP-glucuronosyltransferase 2B31-like
       100513872 UGT2B17; UDP-glucuronosyltransferase 2B17
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31
       100511479 UGT1A3; UDP-glucuronosyltransferase 1-1
       100152910 CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2
       403216 CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
     00983 Drug metabolism - other enzymes [PATH:ssc00983]
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ssc05200]
     05230 Central carbon metabolism in cancer [PATH:ssc05230]
     05231 Choline metabolism in cancer [PATH:ssc05231]
     05202 Transcriptional misregulation in cancers [PATH:ssc05202]
     05206 MicroRNAs in cancer [PATH:ssc05206]
     05205 Proteoglycans in cancer [PATH:ssc05205]
     05204 Chemical carcinogenesis [PATH:ssc05204]
       403103 CYP1A1; cytochrome P450 1A1
       403324 CYP3A29; cytochrome P450 3A29
       403322 CYP3A39; cytochrome P450 3A39
       100126281 CYP3A46; cytochrome P450 3A46
       100144468 CYP3A22; cytochrome P450, subfamily IIIA, polypeptide 22
       397590 PTGS2; prostaglandin-endoperoxide synthase 2
       100511905 arylamine N-acetyltransferase 1
       100152910 CYP1A2; cytochrome P450, family 1, subfamily A, polypeptide 2
       396640 SULT1A3; sulfotransferase family 1A member 3
       100625479 cytochrome P450 1B1-like
       403106 CYP2C32; cytochrome P450 2C32
       403215 CYP2C49; cytochrome P450 2C49
       403111 CYP2C42; cytochrome P450 C42
       403110 CYP2C36; cytochrome P450 2C36
       403107 CYP2C33; cytochrome P450 2C33
       100739741 CYP2C33; cytochrome P450 2C23-like
       397639 EPHX1; epoxide hydrolase 1
       396653 ARNT; aryl hydrocarbon receptor nuclear translocator
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase
       641359 SULT2A1; sulfotransferase family 2A member 1
       100415931 CHRNA7; neuronal acetylcholine receptor subunit alpha-7
       397143 CBR1; carbonyl reductase 1
       100622246 CBR3; carbonyl reductase [NADPH] 1
       397480 HSD11B1; hydroxysteroid 11-beta dehydrogenase 1
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6
       100511841 UGT1A10; UDP-glucuronosyltransferase 1-10
       100515394 UDP-glucuronosyltransferase 2C1-like
       100515741 UDP-glucuronosyltransferase 2B4-like
       100516628 UDP-glucuronosyltransferase 2B18-like
       100624700 UDP-glucuronosyltransferase 2C1-like
       100738495 UDP-glucuronosyltransferase 2B31-like
       100624788 UGT2A1; UDP-glucuronosyltransferase 2A1
       100623255 UDP-glucuronosyltransferase 2B31-like
       100513872 UGT2B17; UDP-glucuronosyltransferase 2B17
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31
       100511479 UGT1A3; UDP-glucuronosyltransferase 1-1
       403216 CYP2E1; cytochrome P450, family 2, subfamily E, polypeptide 1
       403104 CYP2B22; cytochrome P450 2B22
       100155494 aldehyde dehydrogenase family 1 member A3
       100526075 ALDH3A1; aldehyde dehydrogenase 3 family member A1
       100739347 ALDH3B1; aldehyde dehydrogenase 3 family member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like
       106504111 aldehyde dehydrogenase family 1 member A3-like
       100512795 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
       100515071 KYAT1; kynurenine aminotransferase 1
       100157176 KYAT3; kynurenine aminotransferase 3
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K00622 nat; arylamine N-acetyltransferase [EC:2.3.1.5]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K01014 SULT1A; aryl sulfotransferase [EC:2.8.2.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
     05203 Viral carcinogenesis [PATH:ssc05203]
     05210 Colorectal cancer [PATH:ssc05210]
     05212 Pancreatic cancer [PATH:ssc05212]
     05214 Glioma [PATH:ssc05214]
     05216 Thyroid cancer [PATH:ssc05216]
     05221 Acute myeloid leukemia [PATH:ssc05221]
     05220 Chronic myeloid leukemia [PATH:ssc05220]
     05217 Basal cell carcinoma [PATH:ssc05217]
     05218 Melanoma [PATH:ssc05218]
     05211 Renal cell carcinoma [PATH:ssc05211]
     05219 Bladder cancer [PATH:ssc05219]
     05215 Prostate cancer [PATH:ssc05215]
     05213 Endometrial cancer [PATH:ssc05213]
     05224 Breast cancer [PATH:ssc05224]
     05222 Small cell lung cancer [PATH:ssc05222]
     05223 Non-small cell lung cancer [PATH:ssc05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
     05418 Fluid shear stress and atherosclerosis [PATH:ssc05418]
       397028 HSP90AA1; heat shock protein 90 alpha family class A member 1
       396742 HSP90AB1; heat shock protein 90 alpha family class B member 1
       397191 HSP90B1; heat shock protein 90 beta family member 1
       397557 NOS3; nitric oxide synthase 3
       404693 CAV1; caveolin 1
       100125375 CAV2; caveolin 2
       641358 CAV3; caveolin 3
       100154056 CALM1; calmodulin 1
       100516639 calmodulin-like
       396838 CALM3; calmodulin 3
       100522926 CALM2; calmodulin 2
       100738118 calmodulin-like
       100623661 CALML6; calmodulin like 6
       100519528 CALML4; calmodulin-like 4
       100525965 GPC1; glypican 1
       100519770 SDC1; syndecan 1
       100152754 SDC2; syndecan 2
       397528 SDC4; syndecan 4
       100126845 TRPV4; transient receptor potential cation channel subfamily V member 4
       100136900 KEAP1; kelch-like ECH-associated protein 1
       100738260 kelch-like ECH-associated protein 1
       100516343 NFE2L2; nuclear factor, erythroid 2 like 2
       445512 HMOX1; heme oxygenase 1
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       100286873 NQO1; NAD(P)H quinone dehydrogenase 1
       100518718 SQSTM1; sequestosome 1
       397581 TXN; thioredoxin
       100158080 TXN2; thioredoxin 2
       493772 NPPC; natriuretic peptide C
       414411 ASS1; argininosuccinate synthase 1
       100157642 THBD; thrombomodulin
       397121 PLAT; plasminogen activator, tissue type
       414737 CDH5; cadherin 5, type 2 (vascular endothelium)
       397311 KDR; kinase insert domain receptor
       397657 CTNNB1; catenin beta 1
       397504 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       100145903 PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit
       396941 PECAM1; platelet and endothelial cell adhesion molecule 1
       100518131 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       100622663 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       100621789 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       100511937 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100514498 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
       100739510 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       100623707 phosphatidylinositol 3-kinase regulatory subunit alpha-like
       100126861 AKT1; v-akt murine thymoma viral oncogene homolog 1
       100513811 AKT3; AKT serine/threonine kinase 3
       100127478 AKT2; AKT serine/threonine kinase 2
       100520164 MAP2K5; dual specificity mitogen-activated protein kinase kinase 5
       102164433 MAPK7; mitogen-activated protein kinase 7
       100037273 MEF2A; myocyte enhancer factor 2A
       733590 MEF2C; myocyte enhancer factor 2C
       100174959 KLF2; Kruppel like factor 2
       397059 ITGA2B; integrin subunit alpha 2b
       397285 ITGAV; integrin, alpha V
       397063 ITGB3; integrin subunit beta 3
       100154503 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       100145887 ARHGEF2; Rho/Rac guanine nucleotide exchange factor 2
       396849 RHOA; ras homolog family member A
       414396 ACTB; actin beta
       397653 ACTG1; actin gamma 1
       100522469 DUSP1; dual specificity phosphatase 1
       100498783 MIR10A; microRNA 10a
       397020 TNFRSF1A; TNF receptor superfamily member 1A
       100626904 IL1R1; interleukin-1 receptor type 1
       100516362 interleukin-1 receptor type 2-like
       100628112 IL1R2; interleukin 1 receptor type 2
       100135663 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       100127355 IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma
       100135662 CHUK; conserved helix-loop-helix ubiquitous kinase
       100101471 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       751869 NFKB1; nuclear factor kappa B subunit 1
       100135665 RELA; RELA proto-oncogene, NF-kB subunit
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       100520100 MAP2K4; mitogen-activated protein kinase kinase 4
       100520418 MAP2K7; mitogen-activated protein kinase kinase 7
       396610 MAPK8; mitogen-activated protein kinase 8
       100521736 MAPK10; mitogen-activated protein kinase 10
       396609 MAPK9; mitogen-activated protein kinase 9
       100625946 MAP2K6; mitogen-activated protein kinase kinase 6
       574062 MAPK12; mitogen-activated protein kinase 12
       100156630 MAPK14; mitogen-activated protein kinase 14
       100144486 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       396913 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       397391 MMP2; matrix metallopeptidase 2
       654325 MMP9; matrix metallopeptidase 9
       396926 CTSV; cathepsin V
       100515919 CTSL; cathepsin L
       397422 CCL2; chemokine (C-C motif) ligand 2
       396925 VCAM1; vascular cell adhesion molecule 1
       396750 ICAM1; intercellular adhesion molecule 1
       397508 SELE; selectin E
       397086 TNF; tumor necrosis factor
       397094 IL1A; interleukin 1 alpha
       396565 IL1B2; interleukin 1, beta 2
       397122 IL1B1; interleukin 1, beta 1
       396991 IFNG; interferon gamma
       100519764 PDGFA; platelet derived growth factor subunit A
       100626465 PDGFB; platelet derived growth factor subunit B
       396915 EDN1; endothelin 1
       397157 VEGFA; vascular endothelial growth factor A
       100113425 BMP4; bone morphogenetic protein 4
       100127483 BMPR2; bone morphogenetic protein receptor type 2
       397282 ACVR2A; activin A receptor type 2A
       448845 ACVR2B; activin A receptor type 2B
       100152307 ACVR1; activin A receptor type 1
       100169652 BMPR1A; bone morphogenetic protein receptor type 1A
       396691 BMPR1B; bone morphogenetic protein receptor type 1B
       100739747 NOX1; NADPH oxidase 1
       100739822 NOX1; NADPH oxidase 1-like
       397507 CYBA; cytochrome b-245, alpha polypeptide
       100134857 NCF1; neutrophil cytosolic factor 1
       100142665 NCF2; neutrophil cytosolic factor 2
       100627149 RAC3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
       100621675 RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
       100533200 PRKCZ; protein kinase C zeta
       100624971 PIAS4; protein inhibitor of activated STAT 4
       397276 TP53; tumor protein p53
       100127140 SUMO4; SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
       397044 SUMO2; small ubiquitin-like modifier 2
       100127139 SUMO1; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)
       100624225 SUMO3; small ubiquitin-like modifier 3
       106506325 pigSUMO1; small ubiquitin-related modifier 1
       100049703 BCL2; BCL2, apoptosis regulator
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1; syndecan 1
K16336 SDC2; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19; kelch-like protein 19
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 trxA; thioredoxin 1
K03671 trxA; thioredoxin 1
K12336 NPPC; natriuretic peptide C
K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5; cadherin 5, type 2, VE-cadherin
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K06471 PECAM1; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B; integrin alpha 2B
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K12791 ARHGEF2; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K04387 IL1R2; interleukin 1 receptor type II
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2; C-C motif chemokine 2
K06527 VCAM1; vascular cell adhesion molecule 1
K06490 ICAM1; intercellular adhesion molecule 1
K06494 SELE; selectin, endothelial cell
K03156 TNF; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1; NADPH oxidase 1
K08008 NOX1; NADPH oxidase 1
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08011 NCF1; neutrophil cytosolic factor 1
K08010 NCF2; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4
K04451 TP53; tumor protein p53
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
     05410 Hypertrophic cardiomyopathy (HCM) [PATH:ssc05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ssc05412]
     05414 Dilated cardiomyopathy (DCM) [PATH:ssc05414]
     05416 Viral myocarditis [PATH:ssc05416]
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance
     01501 beta-Lactam resistance
     01502 Vancomycin resistance
     01503 Cationic antimicrobial peptide (CAMP) resistance
     01504 Antimicrobial resistance genes
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:ssc01521]
     01522 Endocrine resistance [PATH:ssc01522]
     01524 Platinum drug resistance [PATH:ssc01524]
       397186 CTR1; high-affinity copper uptake protein
       397159 ATP7A; ATPase copper transporting alpha
       100049684 ATP7B; ATPase copper transporting beta
       396850 GSTA2; glutathione S-transferase alpha 2
       397117 GSTO1; glutathione S-transferase omega 1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha 1
       100152951 GSTA4; glutathione S-transferase alpha 4
       100153094 GSTT1; glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 GSTO2; glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100513365 MGST2; microsomal glutathione S-transferase 2
       100514231 glutathione S-transferase Mu 3-like
       100525731 glutathione S-transferase P-like
       100623747 glutathione S-transferase omega-2
       100739508 glutathione S-transferase P-like
       100154313 glutathione S-transferase theta-1-like
       100622296 microsomal glutathione S-transferase 2
       100739163 GSTP1; glutathione S-transferase P
       106510200 glutathione S-transferase Mu 1
       397535 ABCC2; ATP binding cassette subfamily C member 2
       100153104 POLH; DNA polymerase eta
       100737500 DNA polymerase eta-like
       100513963 REV3L; DNA polymerase zeta catalytic subunit
       100737059 DNA polymerase zeta catalytic subunit
       100337661 MSH2; mutS homolog 2
       100512158 MSH3; mutS homolog 3
       100624450 MSH6; mutS homolog 6
       100337665 MLH1; mutL homolog 1
       100522779 XPA; XPA, DNA damage recognition and repair factor
       100286808 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       396917 TOP2A; topoisomerase (DNA) II alpha
       100156319 TOP2B; topoisomerase (DNA) II beta
       100049662 BRCA1; BRCA1, DNA repair associated
       100101922 ATM; ATM serine/threonine kinase
       397276 TP53; tumor protein p53
       102157875 CDKN2A; tumor suppressor ARF
       100125959 MDM2; MDM2 proto-oncogene
       396826 FAS; Fas cell surface death receptor
       396633 BAX; BCL2 associated X, apoptosis regulator
       397543 BAK1; BCL2 antagonist/killer 1
       397278 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100517403 BBC3; BCL2 binding component 3
       396726 FASLG; Fas ligand (TNF superfamily, member 6)
       595129 FADD; Fas (TNFRSF6)-associated via death domain
       100737955 FADD; Fas associated via death domain
       595105 CASP8; caspase 8, apoptosis-related cysteine peptidase
       397244 CASP3; caspase 3
       594852 BID; BH3 interacting domain death agonist
       100622859 BIRC2; baculoviral IAP repeat-containing protein 2
       100622590 BIRC3; baculoviral IAP repeat containing 3
       100037300 XIAP; X-linked inhibitor of apoptosis
       397266 BIRC5; baculoviral IAP repeat containing 5
       100516641 ERBB2; erb-b2 receptor tyrosine kinase 2
       100518131 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       100622663 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       100621789 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       100511937 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100514498 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha
       100739510 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       100623707 phosphatidylinositol 3-kinase regulatory subunit alpha-like
       100192445 PDPK1; 3-phosphoinositide dependent protein kinase 1
       100126861 AKT1; v-akt murine thymoma viral oncogene homolog 1
       100513811 AKT3; AKT serine/threonine kinase 3
       100127478 AKT2; AKT serine/threonine kinase 2
       100152215 CDKN1A; cyclin dependent kinase inhibitor 1A
       100623143 cyclin-dependent kinase inhibitor 1
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       100153927 MAPK1; mitogen-activated protein kinase 1
       445013 MAPK3; mitogen-activated protein kinase 3
       100521065 BAD; BCL2 associated agonist of cell death
       397536 BCL2L1; BCL2 like 1
       100049703 BCL2; BCL2, apoptosis regulator
       100170131 CYCS; cytochrome c, somatic
       100519295 cytochrome c-like
       100513283 APAF1; apoptotic peptidase activating factor 1
       100518913 CASP9; caspase 9
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 POLZ1; DNA polymerase zeta [EC:2.7.7.7]
K02350 POLZ1; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:ssc01523]

[ BRITE | KEGG2 | KEGG ]
Last updated: June 25, 2017