KEGG Orthology (KO) - Sus scrofa (pig)

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     KO
 Metabolism
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
     00410 beta-Alanine metabolism [PATH:ssc00410]
     00430 Taurine and hypotaurine metabolism [PATH:ssc00430]
     00440 Phosphonate and phosphinate metabolism [PATH:ssc00440]
     00450 Selenocompound metabolism [PATH:ssc00450]
     00460 Cyanoamino acid metabolism
     00471 D-Glutamine and D-glutamate metabolism [PATH:ssc00471]
     00472 D-Arginine and D-ornithine metabolism [PATH:ssc00472]
     00473 D-Alanine metabolism
     00480 Glutathione metabolism [PATH:ssc00480]
       100519401 GGT7; gamma-glutamyltransferase 7 isoform X1
       100523568 GGT6; gamma-glutamyltransferase 6 isoform X1
       397095 GGT1; gamma-glutamyltranspeptidase 1
       100157523 GGT5; gamma-glutamyltransferase 5 isoform X3
       100524723 CHAC1; glutathione-specific gamma-glutamylcyclotransferase 1
       100517647 CHAC2; putative glutathione-specific gamma-glutamylcyclotransferase 2 isoform X1
       100515137 OPLAH; LOW QUALITY PROTEIN: 5-oxoprolinase
       100522018 GCLC; glutamate--cysteine ligase catalytic subunit isoform X1
       100153977 GCLM; glutamate--cysteine ligase regulatory subunit
       100152660 GSS; glutathione synthetase
       100739583 LAP3; cytosol aminopeptidase isoform X2
       397520 ANPEP; aminopeptidase N
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       100516363 NAT8; N-acetyltransferase 8
       396625 GSR; glutathione reductase, mitochondrial
       397603 IDH2; isocitrate dehydrogenase [NADP], mitochondrial
       102166364 IDH1; isocitrate dehydrogenase [NADP] cytoplasmic isoform X2
       397546 PGD; LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating
       100622986 G6PD; glucose-6-phosphate 1-dehydrogenase isoform X2
       100517534 TXNDC12; thioredoxin domain-containing protein 12
       396920 GPX5; epididymal secretory glutathione peroxidase precursor
       397403 GPX1; glutathione peroxidase 1
       767625 GPX2; glutathione peroxidase 2
       396598 GPX3; glutathione peroxidase 3 precursor
       100154091 GPX6; glutathione peroxidase 6 precursor
       100621417 GPX7; glutathione peroxidase 7
       100519691 GPX8; probable glutathione peroxidase 8 isoform X1
       399537 GPX4; phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor
       414408 ODC1; ornithine decarboxylase
       100520618 ornithine decarboxylase-like
       414385 SRM; spermidine synthase isoform X2
       100153052 SMS; spermine synthase
       102166900 RRM1; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit
       100157205 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X2
       100316853 RRM2; ribonucleoside-diphosphate reductase subunit M2
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]
K07232 CHAC; glutathione-specific gamma-glutamylcyclotransferase [EC:4.3.2.7]
K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205 GCLM; glutamate--cysteine ligase regulatory subunit
K21456 GSS; glutathione synthase [EC:6.3.2.3]
K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11140 ANPEP; aminopeptidase N [EC:3.4.11.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K20838 NAT8; N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-]
K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K05360 TXNDC12; protein-disulfide reductase (glutathione) [EC:1.8.4.2]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K05361 GPX4; phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K00797 speE; spermidine synthase [EC:2.5.1.16]
K00802 SMS; spermine synthase [EC:2.5.1.22]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
     00362 Benzoate degradation
     00627 Aminobenzoate degradation
     00364 Fluorobenzoate degradation
     00625 Chloroalkane and chloroalkene degradation
     00361 Chlorocyclohexane and chlorobenzene degradation
     00623 Toluene degradation
     00622 Xylene degradation
     00633 Nitrotoluene degradation
     00642 Ethylbenzene degradation
     00643 Styrene degradation
     00791 Atrazine degradation
     00930 Caprolactam degradation
     00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
     00363 Bisphenol degradation
     00621 Dioxin degradation
     00626 Naphthalene degradation
     00624 Polycyclic aromatic hydrocarbon degradation
     00365 Furfural degradation
     00984 Steroid degradation
     00980 Metabolism of xenobiotics by cytochrome P450 [PATH:ssc00980]
       403103 CYP1A1; cytochrome P450 1A1
       100625479 cytochrome P450 1B1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       397639 EPHX1; epoxide hydrolase 1 precursor
       641359 SULT2A1; bile salt sulfotransferase
       100152910 CYP1A2; cytochrome P450 1A2
       403216 CYP2E1; cytochrome P450 2E1
       100523190 cytochrome P450 2F3
       106510546 cytochrome P450 2S1
       397337 DHDH; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
       397480 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 isoform 2
       397143 CBR1; carbonyl reductase [NADPH] 1
       100622246 carbonyl reductase [NADPH] 1
       396780 CBR2; carbonyl reductase [NADPH] 2
       100512990 CBR3; carbonyl reductase [NADPH] 3
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       100511331 AKR7A2; aflatoxin B1 aldehyde reductase member 2
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07420 CYP2S1; cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]
K00078 DHDH; dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00081 CBR2; carbonyl reductase 2 [EC:1.1.1.184]
K00084 CBR3; carbonyl reductase 3 [EC:1.1.1.184]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K15303 AKR7; aflatoxin B1 aldehyde reductase
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
     00982 Drug metabolism - cytochrome P450 [PATH:ssc00982]
       397132 FMO1; dimethylaniline monooxygenase [N-oxide-forming] 1
       100152950 FMO5; dimethylaniline monooxygenase [N-oxide-forming] 5
       100523562 FMO3; dimethylaniline monooxygenase [N-oxide-forming] 3
       100525884 FMO2; dimethylaniline monooxygenase [N-oxide-forming] 2 isoform X1
       100621718 FMO4; dimethylaniline monooxygenase [N-oxide-forming] 4 isoform X1
       100151788 dimethylaniline monooxygenase [N-oxide-forming] 5-like
       100523745 putative dimethylaniline monooxygenase [N-oxide-forming] 6 isoform X2
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       414424 MAOA; amine oxidase [flavin-containing] A
       414909 MAOB; amine oxidase [flavin-containing] B
       100523701 AOX1; aldehyde oxidase
       100525616 AOX2; aldehyde oxidase 2
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       100152910 CYP1A2; cytochrome P450 1A2
       403216 CYP2E1; cytochrome P450 2E1
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
     00983 Drug metabolism - other enzymes [PATH:ssc00983]
       397351 HPRT1; hypoxanthine-guanine phosphoribosyltransferase
       100525485 IMPDH2; inosine-5'-monophosphate dehydrogenase 2 isoform X2
       100520873 IMPDH1; inosine-5'-monophosphate dehydrogenase 1 isoform X1
       100512255 GMPS; GMP synthase [glutamine-hydrolyzing] isoform X2
       100157630 TPMT; thiopurine S-methyltransferase
       100515259 XDH; xanthine dehydrogenase/oxidase
       100157088 ITPA; inosine triphosphate pyrophosphatase isoform X3
       397478 CES1; liver carboxylesterase precursor
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       100144519 GUSB; beta-glucuronidase precursor
       100515954 CDA; cytidine deaminase
       397109 DPYD; dihydropyrimidine dehydrogenase [NADP(+)] precursor
       100156500 DPYS; dihydropyrimidinase isoform X1
       100155919 UPB1; beta-ureidopropionase isoform X1
       100522709 UPP2; uridine phosphorylase 2
       100625277 UPP1; uridine phosphorylase 1
       100525976 UCK1; uridine-cytidine kinase 1 isoform X2
       110257383 UCKL1; uridine-cytidine kinase-like 1 isoform X1
       110260302 UCK2; uridine-cytidine kinase 2
       100627619 TK2; thymidine kinase 2, mitochondrial isoform X1
       110255958 TK1; thymidine kinase, cytosolic
       100516340 UMPS; uridine 5'-monophosphate synthase
       100521561 CMPK1; UMP-CMP kinase
       102166900 RRM1; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit
       100157205 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X2
       100316853 RRM2; ribonucleoside-diphosphate reductase subunit M2
       100152763 NME7; nucleoside diphosphate kinase 7 isoform X1
       100233195 NME4; nucleoside diphosphate kinase, mitochondrial
       733683 NME2; nucleoside diphosphate kinase B
       100514398 NME3; nucleoside diphosphate kinase 3 isoform 1 precursor
       100520587 NME6; nucleoside diphosphate kinase 6
       100142626 NME1; nucleoside diphosphate kinase A
       100621123 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1
       100517120 MPO; LOW QUALITY PROTEIN: myeloperoxidase
       100511905 arylamine N-acetyltransferase 1
       403216 CYP2E1; cytochrome P450 2E1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00569 TPMT; thiopurine S-methyltransferase [EC:2.1.1.67]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K01519 ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.-]
K01044 CES1; carboxylesterase 1 [EC:3.1.1.1]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
K01489 cdd; cytidine deaminase [EC:3.5.4.5]
K00207 DPYD; dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
K01431 UPB1; beta-ureidopropionase [EC:3.5.1.6]
K00757 udp; uridine phosphorylase [EC:2.4.2.3]
K00757 udp; uridine phosphorylase [EC:2.4.2.3]
K00876 udk; uridine kinase [EC:2.7.1.48]
K00876 udk; uridine kinase [EC:2.7.1.48]
K00876 udk; uridine kinase [EC:2.7.1.48]
K00857 tdk; thymidine kinase [EC:2.7.1.21]
K00857 tdk; thymidine kinase [EC:2.7.1.21]
K13421 UMPS; uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
K13800 CMPK1; UMP-CMP kinase [EC:2.7.4.14]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K00622 nat; arylamine N-acetyltransferase [EC:2.3.1.5]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ssc05200]
       100152102 DCC; netrin receptor DCC isoform X4
       397244 CASP3; caspase-3
       100518913 CASP9; caspase-9 isoform X1
       100188978 APPL1; DCC-interacting protein 13-alpha
       100048953 CDH1; cadherin-1 precursor
       397657 CTNNB1; catenin beta-1
       100153974 CTNNA3; catenin alpha-3 isoform X7
       100525337 CTNNA2; catenin alpha-2 isoform X1
       100523778 CTNNA1; catenin alpha-1
       100523725 AXIN1; axin-1 isoform X1
       100739604 AXIN2; axin-2 isoform X1
       100517932 APC; adenomatous polyposis coli protein
       100579172 APC2; adenomatous polyposis coli protein 2
       100126852 GSK3B; glycogen synthase kinase-3 beta
       100512951 TCF7; transcription factor 7 isoform X1
       100523899 TCF7L1; LOW QUALITY PROTEIN: transcription factor 7-like 1
       100153922 TCF7L2; transcription factor 7-like 2 isoform X26
       100170126 LEF1; lymphoid enhancer-binding factor 1
       397266 BIRC5; baculoviral IAP repeat-containing protein 5
       448810 MYC; myc proto-oncogene protein
       100738589 CCND1; G1/S-specific cyclin-D1
       100525462 WNT1; proto-oncogene Wnt-1
       100516839 WNT2; protein Wnt-2
       100520560 WNT2B; protein Wnt-2b isoform X1
       100514950 WNT3A; protein Wnt-3a isoform X1
       100519512 WNT3; proto-oncogene Wnt-3 isoform X1
       100327037 WNT4; protein Wnt-4
       100516268 WNT5B; LOW QUALITY PROTEIN: protein Wnt-5b
       100627056 WNT5A; protein Wnt-5a isoform X1
       100622044 WNT6; protein Wnt-6
       100153445 WNT7A; protein Wnt-7a
       100626947 WNT7B; protein Wnt-7b isoform X1
       100513655 WNT8B; protein Wnt-8b isoform X1
       100739710 WNT8A; protein Wnt-8a
       100512949 WNT9A; protein Wnt-9a
       100738655 WNT9B; protein Wnt-9b
       100126276 WNT10B; protein Wnt-10b precursor
       100623646 WNT10A; LOW QUALITY PROTEIN: protein Wnt-10a
       100521912 WNT11; protein Wnt-11
       100511484 WNT16; protein Wnt-16
       100513691 FZD7; frizzled-7
       110262227 FZD1; frizzled-1
       100337669 FZD2; frizzled-2 precursor
       100153078 FZD3; frizzled-3 isoform X1
       100520319 FZD4; LOW QUALITY PROTEIN: frizzled-4
       100519058 FZD5; frizzled-5
       110255708 FZD8; LOW QUALITY PROTEIN: frizzled-8
       100157360 FZD6; frizzled-6 precursor
       100511782 FZD10; frizzled-10
       100625784 FZD9; frizzled-9
       100515777 LRP6; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 6
       100524299 LRP5; low-density lipoprotein receptor-related protein 5 isoform X1
       100525170 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X2
       100621038 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100625452 DVL2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2
       110256598 FRAT1; proto-oncogene FRAT1
       110256599 FRAT2; GSK-3-binding protein FRAT2
       100521609 F2R; proteinase-activated receptor 1 precursor
       100514949 F2RL3; proteinase-activated receptor 4
       100512581 LPAR1; lysophosphatidic acid receptor 1
       100038015 LPAR2; lysophosphatidic acid receptor 2
       100113360 LPAR3; lysophosphatidic acid receptor 3
       100038017 LPAR4; lysophosphatidic acid receptor 4 isoform X1
       102161415 LPAR5; lysophosphatidic acid receptor 5
       100738399 LPAR6; lysophosphatidic acid receptor 6
       100519976 AGTR1; type-1 angiotensin II receptor
       100525156 GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1
       100522824 GNA13; guanine nucleotide-binding protein subunit alpha-13
       100523324 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X5
       100157291 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
       100518073 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X11
       100516377 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
       396849 RHOA; transforming protein RhoA
       397447 ROCK1; rho-associated protein kinase 1
       397445 ROCK2; rho-associated protein kinase 2 isoform X1
       494460 CXCL12; stromal cell-derived factor 1 precursor
       396659 CXCR4; C-X-C chemokine receptor type 4
       100144421 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
       100144419 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       397523 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       100515879 PTGER1; prostaglandin E2 receptor EP1 subtype isoform X1
       100127164 PTGER2; prostaglandin E2 receptor EP2 subtype
       396811 PTGER3; prostaglandin E2 receptor EP3 subtype
       100625072 PTGER4; prostaglandin E2 receptor EP4 subtype
       100049657 GNAS; SCG6 (secretogranin VI) isoform SCG6
       100624934 ADCY1; adenylate cyclase type 1
       100517503 ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2
       100514402 ADCY3; adenylate cyclase type 3
       100152067 ADCY4; adenylate cyclase type 4
       100155970 ADCY5; adenylate cyclase type 5 isoform X1
       100522613 ADCY6; LOW QUALITY PROTEIN: adenylate cyclase type 6
       100620994 ADCY7; adenylate cyclase type 7 isoform X1
       100622999 ADCY8; adenylate cyclase type 8 isoform X1
       100625423 ADCY9; adenylate cyclase type 9 isoform X1
       397652 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1
       100623628 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       110261346 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       100516546 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       100154522 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       100524280 GNB4; guanine nucleotide-binding protein subunit beta-4
       100157949 GNB5; guanine nucleotide-binding protein subunit beta-5
       102165618 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       100620948 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 isoform X1
       102167388 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       102166994 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       100621275 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       100622520 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1
       100515992 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 isoform X1
       100522202 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       100270820 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       100520008 GNG14; uncharacterized LOC105372280 homolog
       100511870 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       100519790 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 isoform X1
       100621431 uncharacterized protein LOC100621431 isoform X1
       100153454 COL4A2; collagen alpha-2(IV) chain
       100515336 COL4A1; LOW QUALITY PROTEIN: collagen alpha-1(IV) chain
       100620724 COL4A6; LOW QUALITY PROTEIN: collagen alpha-6(IV) chain
       100621403 COL4A4; LOW QUALITY PROTEIN: collagen alpha-4(IV) chain
       100621504 COL4A3; LOW QUALITY PROTEIN: collagen alpha-3(IV) chain
       100737091 COL4A5; collagen alpha-5(IV) chain isoform X1
       100154420 LAMA2; LOW QUALITY PROTEIN: laminin subunit alpha-2
       100625589 LAMA1; LOW QUALITY PROTEIN: laminin subunit alpha-1
       100511642 LAMA3; laminin subunit alpha-3 isoform X1
       110257482 LAMA5; laminin subunit alpha-5 isoform X1
       100154581 LAMA4; LOW QUALITY PROTEIN: laminin subunit alpha-4
       396707 LAMB1; LOW QUALITY PROTEIN: laminin subunit beta-1
       101101688 LAMB2; laminin subunit beta-2
       100736655 LAMB3; LOW QUALITY PROTEIN: laminin subunit beta-3
       100623759 LAMB4; LOW QUALITY PROTEIN: laminin subunit beta-4
       100514785 LAMC1; laminin subunit gamma-1 precursor
       100624264 LAMC2; laminin subunit gamma-2
       100157958 LAMC3; LOW QUALITY PROTEIN: laminin subunit gamma-3
       397620 FN1; LOW QUALITY PROTEIN: fibronectin
       397483 ITGA2; integrin alpha-2 precursor
       397059 ITGA2B; integrin alpha-IIb precursor
       100517053 ITGA3; integrin alpha-3
       100158200 ITGA6; LOW QUALITY PROTEIN: integrin alpha-6
       397285 ITGAV; integrin alpha-V precursor
       397019 ITGB1; integrin beta-1 precursor
       102167153 PTK2; focal adhesion kinase 1 isoform X1
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100156264 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       100738625 NKX3-1; homeobox protein Nkx-3.1
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       100135662 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
       100101471 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
       100127355 IKBKG; NF-kappa-B essential modulator
       406188 NFKBIA; NF-kappa-B inhibitor alpha
       751869 NFKB1; nuclear factor NF-kappa-B p105 subunit
       100153829 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1
       100135665 RELA; transcription factor p65
       397590 PTGS2; prostaglandin G/H synthase 2 precursor
       396859 NOS2; nitric oxide synthase, inducible
       100049703 BCL2; apoptosis regulator Bcl-2 isoform X1
       100622859 baculoviral IAP repeat-containing protein 2 isoform X1
       100622590 BIRC3; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 3
       100037300 XIAP; E3 ubiquitin-protein ligase XIAP
       397536 BCL2L1; bcl-2-like protein 1
       100627029 TRAF1; TNF receptor-associated factor 1
       100513840 TRAF2; TNF receptor-associated factor 2
       100156979 TRAF3; TNF receptor-associated factor 3 isoform X1
       100518396 TRAF4; TNF receptor-associated factor 4
       396616 TRAF5; TNF receptor-associated factor 5 isoform X2
       396629 TRAF6; TNF receptor-associated factor 6
       100127359 MTOR; serine/threonine-protein kinase mTOR
       100127158 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100512153 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100521065 BAD; LOW QUALITY PROTEIN: bcl2-associated agonist of cell death
       397077 FOXO1; forkhead box protein O1
       100125959 MDM2; E3 ubiquitin-protein ligase Mdm2
       397276 TP53; cellular tumor antigen p53
       397584 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100152215 CDKN1A; LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1
       100157974 BCR; breakpoint cluster region protein isoform X1
       100524544 ABL1; tyrosine-protein kinase ABL1 isoform X1
       100192444 CRK; adapter molecule crk
       100525363 CRKL; crk-like protein
       100518854 CBL; E3 ubiquitin-protein ligase CBL isoform X1
       397550 STAT5A; signal transducer and activator of transcription 5A
       397340 STAT5B; signal transducer and activator of transcription 5B
       100157844 PIM1; serine/threonine-protein kinase pim-1
       100621339 PIM2; serine/threonine-protein kinase pim-2
       100127469 BDKRB1; B1 bradykinin receptor
       110255240 BDKRB2; B2 bradykinin receptor isoform X2
       397457 EDNRA; endothelin-1 receptor precursor
       414911 EDNRB; endothelin B receptor precursor
       654405 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       733588 GNA11; guanine nucleotide-binding protein subunit alpha-11
       100152679 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       100157641 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       100516581 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
       100525148 PLCB3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
       397184 PRKCA; LOW QUALITY PROTEIN: protein kinase C alpha type
       100522792 PRKCB; protein kinase C beta type isoform X1
       100518074 PRKCG; protein kinase C gamma type isoform X3
       396868 IL2; interleukin-2 precursor
       397225 IL4; interleukin-4 precursor
       397409 IL5; interleukin-5 precursor
       399500 IL6; interleukin-6 precursor
       397253 IL7; interleukin-7 precursor
       397053 IL12A; interleukin-12 subunit alpha
       397076 IL12B; interleukin-12 subunit beta precursor
       396721 IL13; interleukin-13 precursor
       397683 IL15; interleukin-15 precursor
       100155546 IL23A; interleukin-23 subunit alpha precursor
       397249 EPO; erythropoietin precursor
       397686 IFNA1; interferon alpha-1 precursor
       100153724 IFN-ALPHA-8; uncharacterized protein LOC100153724 precursor
       100153661 interferon alpha-14 precursor
       100157766 IFN-ALPHA-9; uncharacterized protein LOC100157766 precursor
       100152100 IFN-ALPHA-13; uncharacterized protein LOC100152100 precursor
       100152504 IFN-ALPHA-15; uncharacterized protein LOC100152504 precursor
       100310806 IFN-ALPHAOMEGA; interferon-alphaomega precursor
       396991 IFNG; interferon gamma precursor
       396814 IL2RA; interleukin-2 receptor subunit alpha precursor
       100621776 IL2RB; interleukin-2 receptor subunit beta isoform X1
       397156 IL2RG; cytokine receptor common subunit gamma precursor
       397614 IL4R; interleukin-4 receptor subunit alpha precursor
       100153254 CSF2RB; cytokine receptor common subunit beta
       100137085 IL5RA; interleukin-5 receptor subunit alpha isoform X2
       399522 IL6R; interleukin-6 receptor subunit alpha precursor
       100037294 IL6ST; interleukin-6 receptor subunit beta precursor
       100271930 IL7R; interleukin-7 receptor subunit alpha precursor
       100271900 IL12RB1; interleukin-12 receptor subunit beta-1 precursor
       397178 IL12RB2; interleukin-12 receptor subunit beta-2 precursor
       397615 IL13RA1; interleukin-13 receptor subunit alpha-1 precursor
       733692 IL15RA; interleukin-15 receptor subunit alpha isoform X2
       733613 IL23R; interleukin-23 receptor
       397554 EPOR; erythropoietin receptor precursor
       396658 IFNAR1; interferon alpha/beta receptor 1 precursor
       100533555 IFNAR2; interferon alpha/beta receptor 2
       100152238 IFNGR1; interferon gamma receptor 1 precursor
       100126864 IFNGR2; interferon gamma receptor 2 precursor
       100515021 EML4; echinoderm microtubule-associated protein-like 4 isoform X3
       100518423 ALK; ALK tyrosine kinase receptor
       100522721 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
       100626093 RASGRP2; RAS guanyl-releasing protein 2
       100511446 RASGRP3; ras guanyl-releasing protein 3 isoform X1
       100516199 RASGRP4; RAS guanyl-releasing protein 4
       397202 JAK1; tyrosine-protein kinase JAK1
       397201 JAK2; tyrosine-protein kinase JAK2
       100518649 JAK3; tyrosine-protein kinase JAK3 isoform X1
       733648 STAT3; signal transducer and activator of transcription 3
       396655 STAT1; signal transducer and activator of transcription 1
       396923 STAT2; signal transducer and activator of transcription 2
       397261 STAT4; signal transducer and activator of transcription 4
       100153518 STAT6; signal transducer and activator of transcription 6 isoform 1
       397157 VEGFA; vascular endothelial growth factor A precursor
       100521837 VEGFB; vascular endothelial growth factor B isoform X2
       100156404 PGF; placenta growth factor isoform X1
       100155670 VEGFD; vascular endothelial growth factor D
       100525960 VEGFC; vascular endothelial growth factor C isoform X1
       397484 TGFA; protransforming growth factor alpha precursor
       397083 EGF; pro-epidermal growth factor precursor
       397070 EGFR; epidermal growth factor receptor precursor
       100516641 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       100519764 PDGFA; platelet-derived growth factor subunit A isoform X5
       100627123 PDGFRA; platelet-derived growth factor receptor alpha precursor
       102166564 PDGFRB; platelet-derived growth factor receptor beta
       397491 IGF1; insulin-like growth factor I precursor
       396916 IGF2; insulin-like growth factor II preproprotein
       397350 IGF1R; insulin-like growth factor 1 receptor precursor
       397509 KITLG; kit ligand precursor
       396810 KIT; mast/stem cell growth factor receptor Kit precursor
       100515445 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X2
       100525120 HGF; hepatocyte growth factor isoform X3
       654328 MET; hepatocyte growth factor receptor precursor
       397497 FGF1; fibroblast growth factor 1
       397643 FGF2; fibroblast growth factor 2
       396717 FGF9; fibroblast growth factor 9
       100155720 FGF17; fibroblast growth factor 17
       100152116 FGF6; fibroblast growth factor 6
       100152223 FGF16; fibroblast growth factor 16
       100156242 FGF8; LOW QUALITY PROTEIN: fibroblast growth factor 8
       100513672 FGF5; fibroblast growth factor 5 isoform X1
       100516301 FGF20; fibroblast growth factor 20
       100518595 FGF4; fibroblast growth factor 4
       100519127 FGF3; fibroblast growth factor 3
       100525013 FGF18; fibroblast growth factor 18 isoform X2
       100525086 FGF10; fibroblast growth factor 10
       397281 FGF7; fibroblast growth factor 7
       110259378 FGF22; fibroblast growth factor 22
       100518950 FGF19; fibroblast growth factor 19
       100302504 FGF21; fibroblast growth factor 21 precursor
       100155339 FGF23; fibroblast growth factor 23
       100153248 FGFR1; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1
       396762 FGFR2; fibroblast growth factor receptor 2 precursor
       100514115 FGFR3; fibroblast growth factor receptor 3 isoform X1
       100127133 FGFR4; fibroblast growth factor receptor 4
       100192436 GRB2; growth factor receptor-bound protein 2
       100156602 SOS2; son of sevenless homolog 2
       100520187 SOS1; son of sevenless homolog 1 isoform X1
       110259208 HRAS; GTPase HRas isoform X1
       100518251 KRAS; GTPase KRas isoform X2
       100739349 NRAS; GTPase NRas precursor
       397601 ARAF; serine/threonine-protein kinase A-Raf
       100514612 BRAF; serine/threonine-protein kinase B-raf isoform X6
       100737448 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100233191 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100525505 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100153927 MAPK1; mitogen-activated protein kinase 1
       445013 MAPK3; mitogen-activated protein kinase 3
       396913 JUN; transcription factor AP-1
       100144486 FOS; proto-oncogene c-Fos
       100302363 ETS1; protein C-ets-1
       397320 MMP1; interstitial collagenase precursor
       397391 MMP2; 72 kDa type IV collagenase precursor
       654325 MMP9; matrix metalloproteinase-9 precursor
       396880 CXCL8; interleukin-8 precursor
       100144492 CDK4; cyclin-dependent kinase 4
       100155053 RET; LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase receptor Ret
       100155896 CCDC6; coiled-coil domain-containing protein 6
       100156184 NCOA4; nuclear receptor coactivator 4
       100154471 NTRK1; high affinity nerve growth factor receptor
       414388 TPM3; tropomyosin alpha-3 chain
       100520507 TPR; nucleoprotein TPR isoform X2
       414406 TFG; protein TFG isoform X1
       100516830 RASSF1; ras association domain-containing protein 1 isoform X2
       100521638 RASSF5; ras association domain-containing protein 5 isoform X1
       100517317 STK4; serine/threonine-protein kinase 4 isoform X1
       100155578 DAPK2; death-associated protein kinase 2
       100516103 DAPK1; death-associated protein kinase 1 isoform X1
       100624415 DAPK3; death-associated protein kinase 3
       100152497 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       100518663 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
       100522002 ELK1; ETS domain-containing protein Elk-1
       100154056 CALM1; calmodulin
       396838 CALM3; calmodulin
       100522926 CALM2; calmodulin
       100738118 CALML5; calmodulin-like protein 5
       100623661 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6
       100519528 CALML4; calmodulin-like 4
       397674 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta
       397394 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma
       100626014 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X7
       100516166 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
       100513970 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
       100622254 RALA; ras-related protein Ral-A isoform X2
       100624229 RALB; ras-related protein Ral-B
       100519155 RALBP1; ralA-binding protein 1
       780428 CDC42; cell division control protein 42 homolog
       100627149 RAC1; ras-related C3 botulinum toxin substrate 1
       100621675 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       110255928 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       396610 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100521736 MAPK10; mitogen-activated protein kinase 10 isoform X3
       396609 MAPK9; mitogen-activated protein kinase 9 isoform X4
       397671 PPARG; peroxisome proliferator-activated receptor gamma
       397306 RXRA; retinoic acid receptor RXR-alpha isoform X1
       100156801 RXRB; retinoic acid receptor RXR-beta
       445465 RXRG; retinoic acid receptor RXR-gamma
       396710 RARB; LOW QUALITY PROTEIN: retinoic acid receptor beta
       397435 ESR1; estrogen receptor
       396697 ESR2; estrogen receptor beta
       574068 NCOA1; nuclear receptor coactivator 1
       100135659 NCOA3; nuclear receptor coactivator 3
       396575 SP1; transcription factor Sp1 isoform X1
       397297 PPARD; peroxisome proliferator-activated receptor delta
       397592 JUP; junction plakoglobin
       100625290 ZBTB16; zinc finger and BTB domain-containing protein 16
       100157336 PML; LOW QUALITY PROTEIN: protein PML
       396709 RARA; retinoic acid receptor alpha isoform X2
       100512633 RUNX1; runt-related transcription factor 1
       100155449 RUNX1T1; LOW QUALITY PROTEIN: protein CBFA2T1
       414912 SPI1; transcription factor PU.1
       397307 CEBPA; CCAAT/enhancer-binding protein alpha
       100620339 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1
       100622336 CSF3R; granulocyte colony-stimulating factor receptor
       100517086 CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1
       100153846 E2F1; transcription factor E2F1
       110261113 E2F2; transcription factor E2F2
       100154407 E2F3; transcription factor E2F3 isoform X1
       100517170 MAX; protein max isoform X1
       100620358 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
       397227 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       397162 CCND2; G1/S-specific cyclin-D2
       780426 CCND3; G1/S-specific cyclin-D3
       100155110 CKS1B; cyclin-dependent kinases regulatory subunit 1
       100520933 CKS2; cyclin-dependent kinases regulatory subunit 2
       100520183 LOW QUALITY PROTEIN: S-phase kinase-associated protein 1
       100524037 CUL1; cullin-1
       110260638 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1
       100329128 SKP2; S-phase kinase-associated protein 2
       100154715 CDK2; cyclin-dependent kinase 2
       100512048 CCNE2; G1/S-specific cyclin-E2
       100523248 CCNE1; G1/S-specific cyclin-E1
       100151828 RB1; retinoblastoma-associated protein
       100152997 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       733669 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       100621090 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       396633 BAX; apoptosis regulator BAX isoform X1
       397543 BAK1; bcl-2 homologous antagonist/killer isoform X2
       100513197 DDB2; DNA damage-binding protein 2 isoform X2
       100518650 POLK; LOW QUALITY PROTEIN: DNA polymerase kappa
       492280 TERT; telomerase reverse transcriptase
       414902 MITF; microphthalmia-associated transcription factor
       397078 TGFB1; transforming growth factor beta-1 precursor
       397084 TGFB2; transforming growth factor beta-2 isoform X1
       397400 TGFB3; transforming growth factor beta-3 precursor
       396665 TGFBR1; TGF-beta receptor type-1 precursor
       100038019 TGFBR2; TGF-beta receptor type-2
       397260 SMAD3; mothers against decapentaplegic homolog 3
       100155304 SMAD2; mothers against decapentaplegic homolog 2
       397142 SMAD4; mothers against decapentaplegic homolog 4
       100518275 MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X1
       100154421 CTBP2; C-terminal-binding protein 2 isoform X1
       110262035 CTBP1; C-terminal-binding protein 1 isoform X1
       100156170 HDAC2; histone deacetylase 2
       100622482 HDAC1; histone deacetylase 1
       100337665 MLH1; DNA mismatch repair protein Mlh1
       100337661 MSH2; DNA mismatch repair protein Msh2
       100512158 MSH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh3
       100624450 MSH6; DNA mismatch repair protein Msh6 isoform X2
       100624979 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein
       100141309 RAD51; DNA repair protein RAD51 homolog 1
       396726 FASLG; tumor necrosis factor ligand superfamily member 6
       396826 FAS; tumor necrosis factor receptor superfamily member 6 precursor
       595129 FADD; FAS-associated death domain protein
       595105 CASP8; caspase-8
       594852 BID; BH3-interacting domain death agonist
       397278 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100517403 BBC3; bcl-2-binding component 3 isoform X3
       396632 BCL2L11; bcl-2-like protein 11 isoform 2
       100170131 CYCS; cytochrome c
       100519295 cytochrome c-like
       100513283 APAF1; apoptotic protease-activating factor 1 isoform X1
       100156777 CASP7; caspase-7 isoform X1
       100136900 KEAP1; kelch-like ECH-associated protein 1
       100516343 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X4
       445512 HMOX1; heme oxygenase 1
       100286873 NQO1; NAD(P)H dehydrogenase [quinone] 1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       396681 TXNRD1; thioredoxin reductase 1, cytoplasmic
       100519799 TXNRD3; LOW QUALITY PROTEIN: thioredoxin reductase 3
       100156736 TXNRD2; thioredoxin reductase 2, mitochondrial
       100739306 VHL; von Hippel-Lindau disease tumor suppressor
       100153381 ELOC; elongin-C
       100519651 ELOB; elongin-B
       100512186 CUL2; cullin-2
       100152368 EGLN3; egl nine homolog 3
       100153461 EGLN1; egl nine homolog 1 isoform X1
       100523673 EGLN2; LOW QUALITY PROTEIN: egl nine homolog 2
       100627128 FH; fumarate hydratase, mitochondrial
       396696 HIF1A; hypoxia-inducible factor 1-alpha
       100037272 EPAS1; endothelial PAS domain-containing protein 1
       396653 ARNT; aryl hydrocarbon receptor nuclear translocator
       100157219 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X3
       100156226 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300
       100620215 CREBBP; CREB-binding protein
       102164419 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
       100156773 JAG1; protein jagged-1 isoform X2
       100522743 JAG2; protein jagged-2 isoform X1
       100152163 DLL4; delta-like protein 4 precursor
       100520433 DLL3; delta-like protein 3
       100620481 DLL1; delta-like protein 1 isoform X1
       110258061 NOTCH1; neurogenic locus notch homolog protein 1
       100153369 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       102158881 NOTCH3; neurogenic locus notch homolog protein 3
       100144522 NOTCH4; neurogenic locus notch homolog protein 4 precursor
       100499567 HES1; transcription factor HES-1
       110261433 HES5; transcription factor HES-5
       100152404 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2
       100157952 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2
       100518256 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein isoform X1
       100518179 FLT4; vascular endothelial growth factor receptor 3
       100512749 SHH; sonic hedgehog protein preproprotein
       100627504 PTCH1; protein patched homolog 1 isoform X1
       100515110 SMO; smoothened homolog
       100624604 KIF7; kinesin-like protein KIF7 isoform X1
       100155412 SUFU; LOW QUALITY PROTEIN: suppressor of fused homolog
       100520490 GLI1; zinc finger protein GLI1
       100520334 GLI2; zinc finger protein GLI2
       100516888 GLI3; transcriptional activator GLI3 isoform X1
       100157103 BMP2; bone morphogenetic protein 2 precursor
       100113425 BMP4; bone morphogenetic protein 4 precursor
       100525059 HHIP; hedgehog-interacting protein isoform X1
       100623280 PTCH2; protein patched homolog 2 isoform X1
       397582 AR; androgen receptor
       397028 HSP90AA1; heat shock protein HSP 90-alpha
       396742 HSP90AB1; heat shock protein HSP 90-beta
       397191 HSP90B1; endoplasmin precursor
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K06237 COL4A; collagen, type IV, alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; proto-oncogene C-crk
K04438 CRK; proto-oncogene C-crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23, alpha subunit p19
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K10054 PML; probable transcription factor PML
K08527 RARA; retinoic acid receptor alpha
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; runt-related transcription factor 1; translocated to, 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; ecotropic virus integration site 1 protein
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 TCEB1; transcription elongation factor B, polypeptide 1
K03873 TCEB2; transcription elongation factor B, polypeptide 2
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
     05230 Central carbon metabolism in cancer [PATH:ssc05230]
     05231 Choline metabolism in cancer [PATH:ssc05231]
     05202 Transcriptional misregulation in cancers [PATH:ssc05202]
     05206 MicroRNAs in cancer [PATH:ssc05206]
     05205 Proteoglycans in cancer [PATH:ssc05205]
     05204 Chemical carcinogenesis [PATH:ssc05204]
       403103 CYP1A1; cytochrome P450 1A1
       403324 CYP3A29; cytochrome P450 3A29
       100126281 CYP3A46; cytochrome P450 3A46
       100144468 CYP3A22; cytochrome P450, subfamily IIIA, polypeptide 22
       397590 PTGS2; prostaglandin G/H synthase 2 precursor
       100511905 arylamine N-acetyltransferase 1
       100152910 CYP1A2; cytochrome P450 1A2
       396640 SULT1A3; sulfotransferase 1A3
       100625479 cytochrome P450 1B1
       403106 CYP2C32; cytochrome P450 2C18
       403215 CYP2C49; cytochrome P450 2C49 precursor
       403111 CYP2C42; cytochrome P450 2C42 precursor
       403110 CYP2C36; cytochrome P450 2C42
       403107 CYP2C33; cytochrome P450 2C33
       100739741 cytochrome P450 2C23-like
       397639 EPHX1; epoxide hydrolase 1 precursor
       396653 ARNT; aryl hydrocarbon receptor nuclear translocator
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       641359 SULT2A1; bile salt sulfotransferase
       100415931 CHRNA7; neuronal acetylcholine receptor subunit alpha-7
       397143 CBR1; carbonyl reductase [NADPH] 1
       100622246 carbonyl reductase [NADPH] 1
       397480 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 isoform 2
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       403216 CYP2E1; cytochrome P450 2E1
       403104 CYP2B22; cytochrome P450 2B22 precursor
       102165015 cytochrome P450 2B4-like isoform X1
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
       100515071 KYAT1; kynurenine--oxoglutarate transaminase 1 isoform X4
       100157176 KYAT3; kynurenine--oxoglutarate transaminase 3 isoform X2
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K00622 nat; arylamine N-acetyltransferase [EC:2.3.1.5]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K01014 SULT1A; aryl sulfotransferase [EC:2.8.2.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
     05203 Viral carcinogenesis [PATH:ssc05203]
     05210 Colorectal cancer [PATH:ssc05210]
     05212 Pancreatic cancer [PATH:ssc05212]
     05225 Hepatocellular carcinoma [PATH:ssc05225]
       397484 TGFA; protransforming growth factor alpha precursor
       397070 EGFR; epidermal growth factor receptor precursor
       396916 IGF2; insulin-like growth factor II preproprotein
       397350 IGF1R; insulin-like growth factor 1 receptor precursor
       100152497 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       100518663 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
       397184 PRKCA; LOW QUALITY PROTEIN: protein kinase C alpha type
       100522792 PRKCB; protein kinase C beta type isoform X1
       100518074 PRKCG; protein kinase C gamma type isoform X3
       100522002 ELK1; ETS domain-containing protein Elk-1
       100156321 SHC1; SHC-transforming protein 1 isoform X2
       110259382 SHC2; SHC-transforming protein 2
       102164918 SHC3; SHC-transforming protein 3 isoform X1
       100526147 SHC4; SHC-transforming protein 4 isoform X1
       100192436 GRB2; growth factor receptor-bound protein 2
       100156602 SOS2; son of sevenless homolog 2
       100520187 SOS1; son of sevenless homolog 1 isoform X1
       110259208 HRAS; GTPase HRas isoform X1
       100518251 KRAS; GTPase KRas isoform X2
       100739349 NRAS; GTPase NRas precursor
       397601 ARAF; serine/threonine-protein kinase A-Raf
       100514612 BRAF; serine/threonine-protein kinase B-raf isoform X6
       100737448 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100233191 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100525505 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100153927 MAPK1; mitogen-activated protein kinase 1
       445013 MAPK3; mitogen-activated protein kinase 3
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100156264 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       100127359 MTOR; serine/threonine-protein kinase mTOR
       100127158 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100512153 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100521065 BAD; LOW QUALITY PROTEIN: bcl2-associated agonist of cell death
       397536 BCL2L1; bcl-2-like protein 1
       448810 MYC; myc proto-oncogene protein
       100151828 RB1; retinoblastoma-associated protein
       100153846 E2F1; transcription factor E2F1
       110261113 E2F2; transcription factor E2F2
       100154407 E2F3; transcription factor E2F3 isoform X1
       492280 TERT; telomerase reverse transcriptase
       397276 TP53; cellular tumor antigen p53
       100152215 CDKN1A; LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1
       100152997 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       733669 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       100621090 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       396633 BAX; apoptosis regulator BAX isoform X1
       397543 BAK1; bcl-2 homologous antagonist/killer isoform X2
       100513197 DDB2; DNA damage-binding protein 2 isoform X2
       100518650 POLK; LOW QUALITY PROTEIN: DNA polymerase kappa
       100144492 CDK4; cyclin-dependent kinase 4
       100738589 CCND1; G1/S-specific cyclin-D1
       397078 TGFB1; transforming growth factor beta-1 precursor
       397084 TGFB2; transforming growth factor beta-2 isoform X1
       397400 TGFB3; transforming growth factor beta-3 precursor
       396665 TGFBR1; TGF-beta receptor type-1 precursor
       100038019 TGFBR2; TGF-beta receptor type-2
       397260 SMAD3; mothers against decapentaplegic homolog 3
       100155304 SMAD2; mothers against decapentaplegic homolog 2
       397142 SMAD4; mothers against decapentaplegic homolog 4
       100525462 WNT1; proto-oncogene Wnt-1
       100516839 WNT2; protein Wnt-2
       100520560 WNT2B; protein Wnt-2b isoform X1
       100514950 WNT3A; protein Wnt-3a isoform X1
       100519512 WNT3; proto-oncogene Wnt-3 isoform X1
       100327037 WNT4; protein Wnt-4
       100516268 WNT5B; LOW QUALITY PROTEIN: protein Wnt-5b
       100627056 WNT5A; protein Wnt-5a isoform X1
       100622044 WNT6; protein Wnt-6
       100153445 WNT7A; protein Wnt-7a
       100626947 WNT7B; protein Wnt-7b isoform X1
       100513655 WNT8B; protein Wnt-8b isoform X1
       100739710 WNT8A; protein Wnt-8a
       100512949 WNT9A; protein Wnt-9a
       100738655 WNT9B; protein Wnt-9b
       100126276 WNT10B; protein Wnt-10b precursor
       100623646 WNT10A; LOW QUALITY PROTEIN: protein Wnt-10a
       100521912 WNT11; protein Wnt-11
       100511484 WNT16; protein Wnt-16
       100513691 FZD7; frizzled-7
       110262227 FZD1; frizzled-1
       100337669 FZD2; frizzled-2 precursor
       100153078 FZD3; frizzled-3 isoform X1
       100520319 FZD4; LOW QUALITY PROTEIN: frizzled-4
       100519058 FZD5; frizzled-5
       110255708 FZD8; LOW QUALITY PROTEIN: frizzled-8
       100157360 FZD6; frizzled-6 precursor
       100511782 FZD10; frizzled-10
       100625784 FZD9; frizzled-9
       100515777 LRP6; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 6
       100524299 LRP5; low-density lipoprotein receptor-related protein 5 isoform X1
       100525170 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X2
       100621038 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100625452 DVL2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2
       110256598 FRAT1; proto-oncogene FRAT1
       110256599 FRAT2; GSK-3-binding protein FRAT2
       100126852 GSK3B; glycogen synthase kinase-3 beta
       100523725 AXIN1; axin-1 isoform X1
       100739604 AXIN2; axin-2 isoform X1
       100517932 APC; adenomatous polyposis coli protein
       100579172 APC2; adenomatous polyposis coli protein 2
       397657 CTNNB1; catenin beta-1
       100514516 CSNK1A1; casein kinase I isoform X4
       100512951 TCF7; transcription factor 7 isoform X1
       100523899 TCF7L1; LOW QUALITY PROTEIN: transcription factor 7-like 1
       100153922 TCF7L2; transcription factor 7-like 2 isoform X26
       100170126 LEF1; lymphoid enhancer-binding factor 1
       100136900 KEAP1; kelch-like ECH-associated protein 1
       100516343 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X4
       445512 HMOX1; heme oxygenase 1
       100286873 NQO1; NAD(P)H dehydrogenase [quinone] 1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       396681 TXNRD1; thioredoxin reductase 1, cytoplasmic
       100519799 TXNRD3; LOW QUALITY PROTEIN: thioredoxin reductase 3
       100156736 TXNRD2; thioredoxin reductase 2, mitochondrial
       100525120 HGF; hepatocyte growth factor isoform X3
       654328 MET; hepatocyte growth factor receptor precursor
       100511026 GAB1; LOW QUALITY PROTEIN: GRB2-associated-binding protein 1
       414396 ACTB; actin, cytoplasmic 1
       397653 ACTG1; actin, cytoplasmic 2
       100523570 ACTL6A; actin-like protein 6A isoform X1
       100516853 ACTL6B; actin-like protein 6B isoform X2
       100512367 SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
       100521999 SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X3
       100155712 SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
       100511109 PHF10; PHD finger protein 10 isoform X2
       100625938 DPF1; zinc finger protein neuro-d4 isoform X1
       100156555 DPF3; zinc finger protein DPF3
       100152904 ARID1B; AT-rich interactive domain-containing protein 1B isoform X1
       100513359 ARID1A; AT-rich interactive domain-containing protein 1A isoform X1
       100521398 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X1
       100154735 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1
       100157539 SMARCC2; SWI/SNF complex subunit SMARCC2 isoform X7
       100519869 SMARCC1; LOW QUALITY PROTEIN: SWI/SNF complex subunit SMARCC1
       100157302 SMARCA2; probable global transcription activator SNF2L2 isoform X1
       102167672 SMARCA4; transcription activator BRG1 isoform X19
       100625757 ARID2; LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 2
       100525781 PBRM1; protein polybromo-1 isoform X1
       100621103 BRD7; bromodomain-containing protein 7 isoform X1
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-binding protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04500 SMAD2_3; mothers against decapentaplegic homolog 2/3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A; BRG1-associated factor 45A
K22198 BAF45B_C; BRG1-associated factor 45B/C
K22198 BAF45B_C; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1
K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C
K11649 SMARCC; SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
     05226 Gastric cancer [PATH:ssc05226]
     05214 Glioma [PATH:ssc05214]
     05216 Thyroid cancer [PATH:ssc05216]
     05221 Acute myeloid leukemia [PATH:ssc05221]
     05220 Chronic myeloid leukemia [PATH:ssc05220]
     05217 Basal cell carcinoma [PATH:ssc05217]
     05218 Melanoma [PATH:ssc05218]
     05211 Renal cell carcinoma [PATH:ssc05211]
     05219 Bladder cancer [PATH:ssc05219]
     05215 Prostate cancer [PATH:ssc05215]
     05213 Endometrial cancer [PATH:ssc05213]
     05224 Breast cancer [PATH:ssc05224]
     05222 Small cell lung cancer [PATH:ssc05222]
     05223 Non-small cell lung cancer [PATH:ssc05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
     05418 Fluid shear stress and atherosclerosis [PATH:ssc05418]
       397028 HSP90AA1; heat shock protein HSP 90-alpha
       396742 HSP90AB1; heat shock protein HSP 90-beta
       397191 HSP90B1; endoplasmin precursor
       397557 NOS3; nitric oxide synthase, endothelial
       404693 CAV1; caveolin-1 isoform b
       100125375 CAV2; caveolin-2
       641358 CAV3; caveolin-3
       100154056 CALM1; calmodulin
       396838 CALM3; calmodulin
       100522926 CALM2; calmodulin
       100738118 CALML5; calmodulin-like protein 5
       100623661 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6
       100519528 CALML4; calmodulin-like 4
       100525965 GPC1; glypican-1 isoform X2
       100519770 SDC1; syndecan-1 precursor
       100152754 SDC2; syndecan-2 precursor
       397528 SDC4; syndecan-4 precursor
       100126845 TRPV4; transient receptor potential cation channel subfamily V member 4
       100136900 KEAP1; kelch-like ECH-associated protein 1
       100516343 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X4
       445512 HMOX1; heme oxygenase 1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       100286873 NQO1; NAD(P)H dehydrogenase [quinone] 1
       100518718 SQSTM1; sequestosome-1 isoform X1
       397581 TXN; thioredoxin
       100158080 TXN2; thioredoxin, mitochondrial
       493772 NPPC; C-type natriuretic peptide precursor
       414411 ASS1; argininosuccinate synthase
       100157642 THBD; thrombomodulin precursor
       397121 PLAT; tissue-type plasminogen activator precursor
       414737 CDH5; cadherin-5 precursor
       397311 KDR; vascular endothelial growth factor receptor 2 isoform X2
       397657 CTNNB1; catenin beta-1
       397504 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
       100145903 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
       396941 PECAM1; platelet endothelial cell adhesion molecule precursor
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       106504229 MAP2K5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1
       102164433 MAPK7; mitogen-activated protein kinase 7 isoform X1
       100037273 MEF2A; myocyte-specific enhancer factor 2A isoform 2
       733590 MEF2C; myocyte-specific enhancer factor 2C
       100174959 KLF2; Krueppel-like factor 2
       397059 ITGA2B; integrin alpha-IIb precursor
       397285 ITGAV; integrin alpha-V precursor
       397063 ITGB3; integrin beta-3 precursor
       100154503 SRC; proto-oncogene tyrosine-protein kinase Src isoform X3
       102167153 PTK2; focal adhesion kinase 1 isoform X1
       100145887 ARHGEF2; rho guanine nucleotide exchange factor 2
       396849 RHOA; transforming protein RhoA
       414396 ACTB; actin, cytoplasmic 1
       397653 ACTG1; actin, cytoplasmic 2
       100522469 DUSP1; dual specificity protein phosphatase 1
       100498783 MIR10A; ssc-miR-10a-5p
       397020 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A precursor
       100626904 IL1R1; interleukin-1 receptor type 1 isoform X1
       100628112 IL1R2; interleukin-1 receptor type 2 precursor
       100135663 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       100127355 IKBKG; NF-kappa-B essential modulator
       100135662 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
       100101471 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
       751869 NFKB1; nuclear factor NF-kappa-B p105 subunit
       100135665 RELA; transcription factor p65
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       100520100 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X2
       100520418 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X5
       396610 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100521736 MAPK10; mitogen-activated protein kinase 10 isoform X3
       396609 MAPK9; mitogen-activated protein kinase 9 isoform X4
       100625946 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1
       574062 MAPK12; mitogen-activated protein kinase 12
       100156630 MAPK14; mitogen-activated protein kinase 14 isoform X1
       100155841 MAPK13; mitogen-activated protein kinase 13 isoform X1
       100144486 FOS; proto-oncogene c-Fos
       396913 JUN; transcription factor AP-1
       397391 MMP2; 72 kDa type IV collagenase precursor
       654325 MMP9; matrix metalloproteinase-9 precursor
       396926 CTSV; cathepsin L1 precursor
       100515919 CTSL; cathepsin L1
       397422 CCL2; C-C motif chemokine 2 precursor
       396925 VCAM1; vascular cell adhesion protein 1 precursor
       396750 ICAM1; intercellular adhesion molecule 1 precursor
       397508 SELE; E-selectin precursor
       397086 TNF; tumor necrosis factor
       397094 IL1A; interleukin-1 alpha precursor
       396565 IL1B2; interleukin 1, beta
       397122 IL1B; interleukin-1 beta precursor
       396991 IFNG; interferon gamma precursor
       100519764 PDGFA; platelet-derived growth factor subunit A isoform X5
       396915 EDN1; endothelin-1 preproprotein
       397157 VEGFA; vascular endothelial growth factor A precursor
       100113425 BMP4; bone morphogenetic protein 4 precursor
       100127483 BMPR2; bone morphogenetic protein receptor type-2 precursor
       397282 ACVR2A; activin receptor type-2A precursor
       448845 ACVR2B; activin receptor type-2B precursor
       100152307 ACVR1; activin receptor type-1 isoform X2
       100169652 BMPR1A; bone morphogenetic protein receptor type-1A precursor
       396691 BMPR1B; bone morphogenetic protein receptor type-1B
       100739822 NOX1; NADPH oxidase 1 isoform X1
       397507 CYBA; cytochrome b-245 light chain
       100134857 NCF1; neutrophil cytosol factor 1
       100142665 NCF2; neutrophil cytosol factor 2
       100627149 RAC1; ras-related C3 botulinum toxin substrate 1
       100621675 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       110255928 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       100533200 PRKCZ; protein kinase C zeta type
       100624971 PIAS4; E3 SUMO-protein ligase PIAS4
       397276 TP53; cellular tumor antigen p53
       100127140 SUMO4; small ubiquitin-related modifier 4 precursor
       397044 SUMO2; small ubiquitin-related modifier 2 precursor
       100127139 SUMO1; small ubiquitin-related modifier 1 precursor
       100624225 SUMO3; small ubiquitin-related modifier 3
       100049703 BCL2; apoptosis regulator Bcl-2 isoform X1
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1; syndecan 1
K16336 SDC2; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 trxA; thioredoxin 1
K03671 trxA; thioredoxin 1
K12336 NPPC; natriuretic peptide C
K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5; cadherin 5, type 2, VE-cadherin
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K06471 PECAM1; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B; integrin alpha 2B
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K12791 ARHGEF2; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2; C-C motif chemokine 2
K06527 VCAM1; vascular cell adhesion molecule 1
K06490 ICAM1; intercellular adhesion molecule 1
K06494 SELE; selectin, endothelial cell
K03156 TNF; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1; NADPH oxidase 1
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08011 NCF1; neutrophil cytosolic factor 1
K08010 NCF2; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4
K04451 TP53; tumor protein p53
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
     05410 Hypertrophic cardiomyopathy (HCM) [PATH:ssc05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ssc05412]
     05414 Dilated cardiomyopathy (DCM) [PATH:ssc05414]
     05416 Viral myocarditis [PATH:ssc05416]
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance
     01501 beta-Lactam resistance
     01502 Vancomycin resistance
     01503 Cationic antimicrobial peptide (CAMP) resistance
     01504 Antimicrobial resistance genes
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:ssc01521]
     01524 Platinum drug resistance [PATH:ssc01524]
       397186 CTR1; high affinity copper uptake protein 1
       397159 ATP7A; copper-transporting ATPase 1 isoform X1
       100049684 ATP7B; LOW QUALITY PROTEIN: copper-transporting ATPase 2
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100151901 glutathione S-transferase theta-4
       397535 ABCC2; LOW QUALITY PROTEIN: canalicular multispecific organic anion transporter 1
       100153104 POLH; DNA polymerase eta isoform X2
       100513963 REV3L; DNA polymerase zeta catalytic subunit isoform X1
       100337661 MSH2; DNA mismatch repair protein Msh2
       100512158 MSH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh3
       100624450 MSH6; DNA mismatch repair protein Msh6 isoform X2
       100337665 MLH1; DNA mismatch repair protein Mlh1
       100522779 XPA; DNA repair protein complementing XP-A cells
       100286808 ERCC1; DNA excision repair protein ERCC-1
       396917 TOP2A; DNA topoisomerase 2-alpha
       100156319 TOP2B; DNA topoisomerase 2-beta
       100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15
       100101922 ATM; serine-protein kinase ATM
       397276 TP53; cellular tumor antigen p53
       100125959 MDM2; E3 ubiquitin-protein ligase Mdm2
       396826 FAS; tumor necrosis factor receptor superfamily member 6 precursor
       396633 BAX; apoptosis regulator BAX isoform X1
       397543 BAK1; bcl-2 homologous antagonist/killer isoform X2
       397278 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100517403 BBC3; bcl-2-binding component 3 isoform X3
       396726 FASLG; tumor necrosis factor ligand superfamily member 6
       595129 FADD; FAS-associated death domain protein
       595105 CASP8; caspase-8
       397244 CASP3; caspase-3
       594852 BID; BH3-interacting domain death agonist
       100622859 baculoviral IAP repeat-containing protein 2 isoform X1
       100622590 BIRC3; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 3
       100037300 XIAP; E3 ubiquitin-protein ligase XIAP
       397266 BIRC5; baculoviral IAP repeat-containing protein 5
       100516641 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100192445 PDPK1; 3-phosphoinositide-dependent protein kinase 1
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       100152215 CDKN1A; LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       100153927 MAPK1; mitogen-activated protein kinase 1
       445013 MAPK3; mitogen-activated protein kinase 3
       100521065 BAD; LOW QUALITY PROTEIN: bcl2-associated agonist of cell death
       397536 BCL2L1; bcl-2-like protein 1
       100049703 BCL2; apoptosis regulator Bcl-2 isoform X1
       100170131 CYCS; cytochrome c
       100519295 cytochrome c-like
       100513283 APAF1; apoptotic protease-activating factor 1 isoform X1
       100518913 CASP9; caspase-9 isoform X1
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:ssc01523]
     01522 Endocrine resistance [PATH:ssc01522]

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 20, 2018