KEGG Orthology (KO) - Sus scrofa (pig)

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     KO
 Metabolism
 
   Overview
 
   Carbohydrate metabolism
 
   Energy metabolism
 
   Lipid metabolism
 
   Nucleotide metabolism
 
   Amino acid metabolism
 
   Metabolism of other amino acids
     00410 beta-Alanine metabolism [PATH:ssc00410]
     00430 Taurine and hypotaurine metabolism [PATH:ssc00430]
     00440 Phosphonate and phosphinate metabolism [PATH:ssc00440]
     00450 Selenocompound metabolism [PATH:ssc00450]
     00460 Cyanoamino acid metabolism
     00471 D-Glutamine and D-glutamate metabolism [PATH:ssc00471]
     00472 D-Arginine and D-ornithine metabolism [PATH:ssc00472]
     00473 D-Alanine metabolism
     00480 Glutathione metabolism [PATH:ssc00480]
       100519401 GGT7; gamma-glutamyltransferase 7 isoform X1
       100523568 GGT6; gamma-glutamyltransferase 6 isoform X1
       397095 GGT1; gamma-glutamyltranspeptidase 1
       100157523 GGT5; gamma-glutamyltransferase 5 isoform X3
       100515137 OPLAH; LOW QUALITY PROTEIN: 5-oxoprolinase
       100522018 GCLC; glutamate--cysteine ligase catalytic subunit isoform X1
       100153977 GCLM; glutamate--cysteine ligase regulatory subunit
       100152660 GSS; glutathione synthetase
       100739583 LAP3; cytosol aminopeptidase isoform X2
       397520 ANPEP; aminopeptidase N
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       100516363 NAT8; N-acetyltransferase 8
       396625 GSR; glutathione reductase, mitochondrial
       397603 IDH2; isocitrate dehydrogenase [NADP], mitochondrial
       102166364 IDH1; isocitrate dehydrogenase [NADP] cytoplasmic isoform X2
       397546 PGD; LOW QUALITY PROTEIN: 6-phosphogluconate dehydrogenase, decarboxylating
       100622986 G6PD; glucose-6-phosphate 1-dehydrogenase isoform X2
       100517534 TXNDC12; thioredoxin domain-containing protein 12
       396920 GPX5; epididymal secretory glutathione peroxidase precursor
       397403 GPX1; glutathione peroxidase 1
       767625 GPX2; glutathione peroxidase 2
       396598 GPX3; glutathione peroxidase 3 precursor
       100154091 GPX6; glutathione peroxidase 6 precursor
       100621417 GPX7; glutathione peroxidase 7
       100519691 GPX8; probable glutathione peroxidase 8 isoform X1
       399537 GPX4; phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor
       414408 ODC1; ornithine decarboxylase
       100520618 ornithine decarboxylase-like
       414385 SRM; spermidine synthase isoform X2
       100153052 SMS; spermine synthase
       102166900 RRM1; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit
       100157205 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X2
       100316853 RRM2; ribonucleoside-diphosphate reductase subunit M2
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K01469 OPLAH; 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9]
K11204 GCLC; glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
K11205 GCLM; glutamate--cysteine ligase regulatory subunit
K21456 GSS; glutathione synthase [EC:6.3.2.3]
K11142 LAP3; cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5]
K11140 ANPEP; aminopeptidase N [EC:3.4.11.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K20838 NAT8; N-acetyltransferase 8 [EC:2.3.1.80 2.3.1.-]
K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
K05360 TXNDC12; protein-disulfide reductase (glutathione) [EC:1.8.4.2]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K05361 GPX4; phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
K00797 speE; spermidine synthase [EC:2.5.1.16]
K00802 SMS; spermine synthase [EC:2.5.1.22]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
 
   Glycan biosynthesis and metabolism
 
   Metabolism of cofactors and vitamins
 
   Metabolism of terpenoids and polyketides
 
   Biosynthesis of other secondary metabolites
 
   Xenobiotics biodegradation and metabolism
     00362 Benzoate degradation
     00627 Aminobenzoate degradation
     00364 Fluorobenzoate degradation
     00625 Chloroalkane and chloroalkene degradation
     00361 Chlorocyclohexane and chlorobenzene degradation
     00623 Toluene degradation
     00622 Xylene degradation
     00633 Nitrotoluene degradation
     00642 Ethylbenzene degradation
     00643 Styrene degradation
     00791 Atrazine degradation
     00930 Caprolactam degradation
     00351 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation
     00363 Bisphenol degradation
     00621 Dioxin degradation
     00626 Naphthalene degradation
     00624 Polycyclic aromatic hydrocarbon degradation
     00365 Furfural degradation
     00984 Steroid degradation
     00980 Metabolism of xenobiotics by cytochrome P450 [PATH:ssc00980]
       403103 CYP1A1; cytochrome P450 1A1
       100625479 cytochrome P450 1B1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       397639 EPHX1; epoxide hydrolase 1 precursor
       641359 SULT2A1; bile salt sulfotransferase
       100152910 CYP1A2; cytochrome P450 1A2
       403216 CYP2E1; cytochrome P450 2E1
       100523190 cytochrome P450 2F3
       106510546 cytochrome P450 2S1
       397337 DHDH; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
       397480 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 isoform 2
       397143 CBR1; carbonyl reductase [NADPH] 1
       100622246 carbonyl reductase [NADPH] 1
       396780 CBR2; carbonyl reductase [NADPH] 2
       100512990 CBR3; carbonyl reductase [NADPH] 3
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       100511331 AKR7A2; aflatoxin B1 aldehyde reductase member 2
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07416 CYP2F; cytochrome P450 family 2 subfamily F [EC:1.14.14.1]
K07420 CYP2S1; cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]
K00078 DHDH; dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00081 CBR2; carbonyl reductase 2 [EC:1.1.1.184]
K00084 CBR3; carbonyl reductase 3 [EC:1.1.1.184]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K15303 AKR7; aflatoxin B1 aldehyde reductase
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
     00982 Drug metabolism - cytochrome P450 [PATH:ssc00982]
       397132 FMO1; dimethylaniline monooxygenase [N-oxide-forming] 1
       100152950 FMO5; dimethylaniline monooxygenase [N-oxide-forming] 5
       100523562 FMO3; dimethylaniline monooxygenase [N-oxide-forming] 3
       100525884 FMO2; dimethylaniline monooxygenase [N-oxide-forming] 2 isoform X1
       100621718 FMO4; dimethylaniline monooxygenase [N-oxide-forming] 4 isoform X1
       100151788 dimethylaniline monooxygenase [N-oxide-forming] 5-like
       100523745 putative dimethylaniline monooxygenase [N-oxide-forming] 6 isoform X2
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       414424 MAOA; amine oxidase [flavin-containing] A
       414909 MAOB; amine oxidase [flavin-containing] B
       100523701 AOX1; aldehyde oxidase
       100525616 AOX2; aldehyde oxidase 2
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       100152910 CYP1A2; cytochrome P450 1A2
       403216 CYP2E1; cytochrome P450 2E1
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00485 FMO; dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
     00983 Drug metabolism - other enzymes [PATH:ssc00983]
 
   Enzyme families
 
 Genetic Information Processing
 
 Environmental Information Processing
 
 Cellular Processes
 
 Organismal Systems
 
 Human Diseases
 
   Cancers
     05200 Pathways in cancer [PATH:ssc05200]
     05230 Central carbon metabolism in cancer [PATH:ssc05230]
     05231 Choline metabolism in cancer [PATH:ssc05231]
     05202 Transcriptional misregulation in cancers [PATH:ssc05202]
     05206 MicroRNAs in cancer [PATH:ssc05206]
     05205 Proteoglycans in cancer [PATH:ssc05205]
     05204 Chemical carcinogenesis [PATH:ssc05204]
       403103 CYP1A1; cytochrome P450 1A1
       403324 CYP3A29; cytochrome P450 3A29
       100126281 CYP3A46; cytochrome P450 3A46
       100144468 CYP3A22; cytochrome P450, subfamily IIIA, polypeptide 22
       397590 PTGS2; prostaglandin G/H synthase 2 precursor
       100511905 arylamine N-acetyltransferase 1
       100152910 CYP1A2; cytochrome P450 1A2
       396640 SULT1A3; sulfotransferase 1A3
       100625479 cytochrome P450 1B1
       403106 CYP2C32; cytochrome P450 2C18
       403215 CYP2C49; cytochrome P450 2C49 precursor
       403111 CYP2C42; cytochrome P450 2C42 precursor
       403110 CYP2C36; cytochrome P450 2C42
       403107 CYP2C33; cytochrome P450 2C33
       100739741 cytochrome P450 2C23-like
       397639 EPHX1; epoxide hydrolase 1 precursor
       396653 ARNT; aryl hydrocarbon receptor nuclear translocator
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100521480 GSTK1; glutathione S-transferase kappa 1
       100623584 HPGDS; hematopoietic prostaglandin D synthase isoform X1
       641359 SULT2A1; bile salt sulfotransferase
       100415931 CHRNA7; neuronal acetylcholine receptor subunit alpha-7
       397143 CBR1; carbonyl reductase [NADPH] 1
       100622246 carbonyl reductase [NADPH] 1
       397480 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 isoform 2
       100152603 UGT1A6; UDP glucuronosyltransferase 1 family, polypeptide A6 precursor
       100515394 UDP-glucuronosyltransferase 2C1
       100515741 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100516628 UDP-glucuronosyltransferase 2B18-like isoform X1
       100624700 UDP-glucuronosyltransferase 2C1-like isoform X1
       100624788 UDP-glucuronosyltransferase 2A1 isoform X2
       100623255 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31
       100514063 UGT2B31; UDP-glucuronosyltransferase 2B31 precursor
       100623504 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 2B31-like
       403216 CYP2E1; cytochrome P450 2E1
       403104 CYP2B22; cytochrome P450 2B22 precursor
       102165015 cytochrome P450 2B4-like isoform X1
       100526075 ALDH3A1; aldehyde dehydrogenase, dimeric NADP-preferring
       100739347 ALDH3B1; aldehyde dehydrogenase family 3 member B1
       100522421 aldehyde dehydrogenase family 3 member B2-like isoform X1
       102162530 ALDH1A3; aldehyde dehydrogenase family 1 member A3
       100512795 alcohol dehydrogenase class 4 mu/sigma chain
       100512615 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       100513366 ADH4; alcohol dehydrogenase 4
       100513555 ADH5; alcohol dehydrogenase class-3
       100515071 KYAT1; kynurenine--oxoglutarate transaminase 1 isoform X4
       100157176 KYAT3; kynurenine--oxoglutarate transaminase 3 isoform X2
K07408 CYP1A1; cytochrome P450 family 1 subfamily A polypeptide 1 [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K00622 nat; arylamine N-acetyltransferase [EC:2.3.1.5]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A polypeptide 2 [EC:1.14.14.1]
K01014 SULT1A; aryl sulfotransferase [EC:2.8.2.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B polypeptide 1 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K17720 CYP2C18; cytochrome P450 family 2 subfamily C polypeptide 18 [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K13299 GSTK1; glutathione S-transferase kappa 1 [EC:2.5.1.18]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K11822 SULT2A1; bile-salt sulfotransferase [EC:2.8.2.14]
K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E polypeptide 1 [EC:1.14.13.-]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 E1.2.1.5; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K00816 CCBL; kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
     05203 Viral carcinogenesis [PATH:ssc05203]
     05210 Colorectal cancer [PATH:ssc05210]
     05212 Pancreatic cancer [PATH:ssc05212]
     05214 Glioma [PATH:ssc05214]
     05216 Thyroid cancer [PATH:ssc05216]
     05221 Acute myeloid leukemia [PATH:ssc05221]
     05220 Chronic myeloid leukemia [PATH:ssc05220]
     05217 Basal cell carcinoma [PATH:ssc05217]
     05218 Melanoma [PATH:ssc05218]
     05211 Renal cell carcinoma [PATH:ssc05211]
     05219 Bladder cancer [PATH:ssc05219]
     05215 Prostate cancer [PATH:ssc05215]
     05213 Endometrial cancer [PATH:ssc05213]
     05224 Breast cancer [PATH:ssc05224]
     05222 Small cell lung cancer [PATH:ssc05222]
     05223 Non-small cell lung cancer [PATH:ssc05223]
 
   Immune diseases
 
   Neurodegenerative diseases
 
   Substance dependence
 
   Cardiovascular diseases
     05418 Fluid shear stress and atherosclerosis [PATH:ssc05418]
       397028 HSP90AA1; heat shock protein HSP 90-alpha
       396742 HSP90AB1; heat shock protein HSP 90-beta
       397191 HSP90B1; endoplasmin precursor
       397557 NOS3; nitric oxide synthase, endothelial
       404693 CAV1; caveolin-1 isoform b
       100125375 CAV2; caveolin-2
       641358 CAV3; caveolin-3
       100154056 CALM1; calmodulin
       396838 CALM3; calmodulin
       100522926 CALM2; calmodulin
       100738118 CALML5; calmodulin-like protein 5
       100623661 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6
       100519528 CALML4; calmodulin-like 4
       100525965 GPC1; glypican-1 isoform X2
       100519770 SDC1; syndecan-1 precursor
       100152754 SDC2; syndecan-2 precursor
       397528 SDC4; syndecan-4 precursor
       100126845 TRPV4; transient receptor potential cation channel subfamily V member 4
       100136900 KEAP1; kelch-like ECH-associated protein 1
       100516343 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X4
       445512 HMOX1; heme oxygenase 1
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       100286873 NQO1; NAD(P)H dehydrogenase [quinone] 1
       100518718 SQSTM1; sequestosome-1 isoform X1
       397581 TXN; thioredoxin
       100158080 TXN2; thioredoxin, mitochondrial
       493772 NPPC; C-type natriuretic peptide precursor
       414411 ASS1; argininosuccinate synthase
       100157642 THBD; thrombomodulin precursor
       397121 PLAT; tissue-type plasminogen activator precursor
       414737 CDH5; cadherin-5 precursor
       397311 KDR; vascular endothelial growth factor receptor 2 isoform X2
       397657 CTNNB1; catenin beta-1
       397504 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
       100145903 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
       396941 PECAM1; platelet endothelial cell adhesion molecule precursor
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       106504229 MAP2K5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1
       102164433 MAPK7; mitogen-activated protein kinase 7 isoform X1
       100037273 MEF2A; myocyte-specific enhancer factor 2A isoform 2
       733590 MEF2C; myocyte-specific enhancer factor 2C
       100174959 KLF2; Krueppel-like factor 2
       397059 ITGA2B; integrin alpha-IIb precursor
       397285 ITGAV; integrin alpha-V precursor
       397063 ITGB3; integrin beta-3 precursor
       100154503 SRC; proto-oncogene tyrosine-protein kinase Src isoform X3
       102167153 PTK2; focal adhesion kinase 1 isoform X1
       100145887 ARHGEF2; rho guanine nucleotide exchange factor 2
       396849 RHOA; transforming protein RhoA
       414396 ACTB; actin, cytoplasmic 1
       397653 ACTG1; actin, cytoplasmic 2
       100522469 DUSP1; dual specificity protein phosphatase 1
       100498783 MIR10A; ssc-miR-10a-5p
       397020 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A precursor
       100626904 IL1R1; interleukin-1 receptor type 1 isoform X1
       100628112 IL1R2; interleukin-1 receptor type 2 precursor
       100135663 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       100127355 IKBKG; NF-kappa-B essential modulator
       100135662 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
       100101471 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
       751869 NFKB1; nuclear factor NF-kappa-B p105 subunit
       100135665 RELA; transcription factor p65
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       100520100 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X2
       100520418 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X5
       396610 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100521736 MAPK10; mitogen-activated protein kinase 10 isoform X3
       396609 MAPK9; mitogen-activated protein kinase 9 isoform X4
       100625946 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1
       574062 MAPK12; mitogen-activated protein kinase 12
       100156630 MAPK14; mitogen-activated protein kinase 14 isoform X1
       100155841 MAPK13; mitogen-activated protein kinase 13 isoform X1
       100144486 FOS; proto-oncogene c-Fos
       396913 JUN; transcription factor AP-1
       397391 MMP2; 72 kDa type IV collagenase precursor
       654325 MMP9; matrix metalloproteinase-9 precursor
       396926 CTSV; cathepsin L1 precursor
       100515919 CTSL; cathepsin L1
       397422 CCL2; C-C motif chemokine 2 precursor
       396925 VCAM1; vascular cell adhesion protein 1 precursor
       396750 ICAM1; intercellular adhesion molecule 1 precursor
       397508 SELE; E-selectin precursor
       397086 TNF; tumor necrosis factor
       397094 IL1A; interleukin-1 alpha precursor
       396565 IL1B2; interleukin 1, beta
       397122 IL1B; interleukin-1 beta precursor
       396991 IFNG; interferon gamma precursor
       100519764 PDGFA; platelet-derived growth factor subunit A isoform X5
       396915 EDN1; endothelin-1 preproprotein
       397157 VEGFA; vascular endothelial growth factor A precursor
       100113425 BMP4; bone morphogenetic protein 4 precursor
       100127483 BMPR2; bone morphogenetic protein receptor type-2 precursor
       397282 ACVR2A; activin receptor type-2A precursor
       448845 ACVR2B; activin receptor type-2B precursor
       100152307 ACVR1; activin receptor type-1 isoform X2
       100169652 BMPR1A; bone morphogenetic protein receptor type-1A precursor
       396691 BMPR1B; bone morphogenetic protein receptor type-1B
       100739822 NOX1; NADPH oxidase 1 isoform X1
       397507 CYBA; cytochrome b-245 light chain
       100134857 NCF1; neutrophil cytosol factor 1
       100142665 NCF2; neutrophil cytosol factor 2
       100627149 RAC1; ras-related C3 botulinum toxin substrate 1
       100621675 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       110255928 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       100533200 PRKCZ; protein kinase C zeta type
       100624971 PIAS4; E3 SUMO-protein ligase PIAS4
       397276 TP53; cellular tumor antigen p53
       100127140 SUMO4; small ubiquitin-related modifier 4 precursor
       397044 SUMO2; small ubiquitin-related modifier 2 precursor
       100127139 SUMO1; small ubiquitin-related modifier 1 precursor
       100624225 SUMO3; small ubiquitin-related modifier 3
       100049703 BCL2; apoptosis regulator Bcl-2 isoform X1
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08107 GPC1; glypican 1
K06257 SDC1; syndecan 1
K16336 SDC2; syndecan 2
K16338 SDC4; syndecan 4
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K14381 SQSTM1; sequestosome 1
K03671 trxA; thioredoxin 1
K03671 trxA; thioredoxin 1
K12336 NPPC; natriuretic peptide C
K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
K03907 THBD; thrombomodulin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K06533 CDH5; cadherin 5, type 2, VE-cadherin
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K02105 CTNNB1; catenin beta 1
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K06471 PECAM1; platelet/endothelial cell adhesion molecule
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04463 MAP2K5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K09260 MEF2A; MADS-box transcription enhancer factor 2A
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K17845 KLF2; krueppel-like factor 2
K06476 ITGA2B; integrin alpha 2B
K06487 ITGAV; integrin alpha V
K06493 ITGB3; integrin beta 3
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K12791 ARHGEF2; Rho guanine nucleotide exchange factor 2
K04513 RHOA; Ras homolog gene family, member A
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K21278 DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
K16864 MIR10A; microRNA 10a
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04386 IL1R1; interleukin 1 receptor type I
K04387 IL1R2; interleukin 1 receptor type II
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04440 JNK; c-Jun N-terminal kinase [EC:2.7.11.24]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K14624 CCL2; C-C motif chemokine 2
K06527 VCAM1; vascular cell adhesion molecule 1
K06490 ICAM1; intercellular adhesion molecule 1
K06494 SELE; selectin, endothelial cell
K03156 TNF; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K04359 PDGFA; platelet-derived growth factor subunit A
K16366 EDN1; endothelin-1
K05448 VEGFA; vascular endothelial growth factor A
K04662 BMP4; bone morphogenetic protein 4
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K08008 NOX1; NADPH oxidase 1
K08009 CYBA; cytochrome b-245, alpha polypeptide
K08011 NCF1; neutrophil cytosolic factor 1
K08010 NCF2; neutrophil cytosolic factor 2
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4
K04451 TP53; tumor protein p53
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K12160 SUMO; small ubiquitin-related modifier
K02161 BCL2; apoptosis regulator Bcl-2
     05410 Hypertrophic cardiomyopathy (HCM) [PATH:ssc05410]
     05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) [PATH:ssc05412]
     05414 Dilated cardiomyopathy (DCM) [PATH:ssc05414]
     05416 Viral myocarditis [PATH:ssc05416]
 
   Endocrine and metabolic diseases
 
   Infectious diseases
 
   Drug resistance
     01501 beta-Lactam resistance
     01502 Vancomycin resistance
     01503 Cationic antimicrobial peptide (CAMP) resistance
     01504 Antimicrobial resistance genes
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:ssc01521]
     01524 Platinum drug resistance [PATH:ssc01524]
       397186 CTR1; high affinity copper uptake protein 1
       397159 ATP7A; copper-transporting ATPase 1 isoform X1
       100049684 ATP7B; LOW QUALITY PROTEIN: copper-transporting ATPase 2
       397117 GSTO1; glutathione S-transferase omega-1
       397567 MGST1; microsomal glutathione S-transferase 1
       397682 GSTA1; glutathione S-transferase alpha M14
       100152951 GSTA4; glutathione S-transferase A4
       100153094 glutathione S-transferase theta-1
       780435 glutathione S-transferase mu 2
       733607 MGST3; microsomal glutathione S-transferase 3
       100152209 glutathione S-transferase omega-2
       100510917 glutathione S-transferase A4
       100514231 GSTM3; glutathione S-transferase Mu 3
       100739508 glutathione S-transferase P-like
       100622296 MGST2; microsomal glutathione S-transferase 2
       100739163 glutathione S-transferase P-like isoform X1
       106510200 glutathione S-transferase Mu 1
       397535 ABCC2; LOW QUALITY PROTEIN: canalicular multispecific organic anion transporter 1
       100153104 POLH; DNA polymerase eta isoform X2
       100513963 REV3L; DNA polymerase zeta catalytic subunit isoform X1
       100337661 MSH2; DNA mismatch repair protein Msh2
       100512158 MSH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh3
       100624450 MSH6; DNA mismatch repair protein Msh6 isoform X2
       100337665 MLH1; DNA mismatch repair protein Mlh1
       100522779 XPA; DNA repair protein complementing XP-A cells
       100286808 ERCC1; DNA excision repair protein ERCC-1
       396917 TOP2A; DNA topoisomerase 2-alpha
       100156319 TOP2B; DNA topoisomerase 2-beta
       100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15
       100101922 ATM; serine-protein kinase ATM
       397276 TP53; cellular tumor antigen p53
       100125959 MDM2; E3 ubiquitin-protein ligase Mdm2
       396826 FAS; tumor necrosis factor receptor superfamily member 6 precursor
       396633 BAX; apoptosis regulator BAX isoform X1
       397543 BAK1; bcl-2 homologous antagonist/killer isoform X2
       397278 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100517403 BBC3; bcl-2-binding component 3 isoform X3
       396726 FASLG; tumor necrosis factor ligand superfamily member 6
       595129 FADD; FAS-associated death domain protein
       595105 CASP8; caspase-8
       397244 CASP3; caspase-3
       594852 BID; BH3-interacting domain death agonist
       100622859 baculoviral IAP repeat-containing protein 2 isoform X1
       100622590 BIRC3; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 3
       100037300 XIAP; E3 ubiquitin-protein ligase XIAP
       397266 BIRC5; baculoviral IAP repeat-containing protein 5
       100516641 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       100518131 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       100621789 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100622559 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100511937 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       100739510 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100623707 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       100192445 PDPK1; 3-phosphoinositide-dependent protein kinase 1
       100126861 AKT1; RAC-alpha serine/threonine-protein kinase
       100513811 AKT3; RAC-gamma serine/threonine-protein kinase
       100127478 AKT2; RAC-beta serine/threonine-protein kinase
       100152215 CDKN1A; LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1
       100622769 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       100153927 MAPK1; mitogen-activated protein kinase 1
       445013 MAPK3; mitogen-activated protein kinase 3
       100521065 BAD; LOW QUALITY PROTEIN: bcl2-associated agonist of cell death
       397536 BCL2L1; bcl-2-like protein 1
       100049703 BCL2; apoptosis regulator Bcl-2 isoform X1
       100170131 CYCS; cytochrome c
       100519295 cytochrome c-like
       100513283 APAF1; apoptotic protease-activating factor 1 isoform X1
       100518913 CASP9; caspase-9 isoform X1
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K17686 copA; Cu+-exporting ATPase [EC:3.6.3.54]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 POLZ1; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K03164 TOP2; DNA topoisomerase II [EC:5.99.1.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; ataxia telangiectasia mutated family protein [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:ssc01523]
     01522 Endocrine resistance [PATH:ssc01522]

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: September 20, 2017