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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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100155920 ASH1L; histone-lysine N-methyltransferase ASH1L isoform X1
100738665 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
100124382 EHMT2; histone-lysine N-methyltransferase EHMT2
110258080 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X1
100518394 EZH1; histone-lysine N-methyltransferase EZH1
100625497 EZH2; histone-lysine N-methyltransferase EZH2
100623006 KMT2A; histone-lysine N-methyltransferase 2A isoform X1
110260656 KMT2D; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2D
100514805 KMT2C; histone-lysine N-methyltransferase 2C isoform X1
100520742 KMT2B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
100628131 KMT2E; histone-lysine N-methyltransferase 2E isoform X1
100524976 NSD1; histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform X1
100515039 NSD2; histone-lysine N-methyltransferase NSD2 isoform X1
100520868 NSD3; histone-lysine N-methyltransferase NSD3 isoform X3
100518559 PRDM2; LOW QUALITY PROTEIN: PR domain zinc finger protein 2
100518275 MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X1
100524509 PRDM6; putative histone-lysine N-methyltransferase PRDM6 isoform X1
100620538 PRDM7; probable histone-lysine N-methyltransferase PRDM7
102165745 ZNF488; zinc finger protein 488
100514243 PRDM8; PR domain zinc finger protein 8 isoform X1
100522920 PRDM12; PR domain zinc finger protein 12
100624476 PRDM16; LOW QUALITY PROTEIN: PR domain zinc finger protein 16
100511747 SETD1A; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A
100156137 SETD1B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B
100623101 SETD2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD2
100622154 SETD4; SET domain-containing protein 4
100626287 SETD6; LOW QUALITY PROTEIN: N-lysine methyltransferase SETD6
100626704 SETD7; histone-lysine N-methyltransferase SETD7 isoform X3
100626555 KMT5A; N-lysine methyltransferase KMT5A isoform X1
100157920 SETDB1; histone-lysine N-methyltransferase SETDB1 isoform X1
100157885 SETDB2; histone-lysine N-methyltransferase SETDB2 isoform X2
100514009 histone-lysine N-methyltransferase SETMAR
100294702 SMYD1; histone-lysine N-methyltransferase SMYD1
100294706 SMYD2; N-lysine methyltransferase SMYD2
100294707 SMYD3; histone-lysine N-methyltransferase SMYD3
664651 SUV39H2; histone-lysine N-methyltransferase SUV39H2
767626 SUV39H1; histone-lysine N-methyltransferase SUV39H1 isoform X1
100521358 KMT5B; histone-lysine N-methyltransferase KMT5B isoform X1
110261054 KMT5C; histone-lysine N-methyltransferase KMT5C isoform X1
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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COMPASS/SET1 complex
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COMPASS/SET1 complex (yeast)
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MLL-HCF complex
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MLL3/MLL4 complex
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100514805 KMT2C; histone-lysine N-methyltransferase 2C isoform X1
100520742 KMT2B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
100627423 ASH2L; set1/Ash2 histone methyltransferase complex subunit ASH2
100514043 DPY30; protein dpy-30 homolog
100513301 RBBP5; retinoblastoma-binding protein 5 isoform X1
100156729 WDR5; WD repeat-containing protein 5
100627452 WDR5B; WD repeat-containing protein 5B
100156283 NCOA6; nuclear receptor coactivator 6 isoform X1
100621300 PAXIP1; PAX-interacting protein 1 isoform X1
100622905 PAGR1; PAXIP1-associated glutamate-rich protein 1
100154376 KDM6A; lysine-specific demethylase 6A isoform X1
110255320 lysine-specific demethylase 6A-like isoform X1
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K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K14964 ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
K14965 DPY30; protein dpy-30
K14961 RBBP5; COMPASS component SWD1
K14963 WDR5; COMPASS component SWD3
K14963 WDR5; COMPASS component SWD3
K14971 NCOA6; nuclear receptor coactivator 6
K14972 PAXIP1; PAX-interacting protein 1
K14973 PA1; PAXIP1-associated protein 1
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
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Dot1-containing complex
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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