Messenger RNA Biogenesis - Xenopus tropicalis (tropical clawed frog)

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     KO 
 Eukaryotic type

   mRNA processing factors

   mRNA surveillance and transport factors

     Transport factors

       EJC complex

       TREX complex

       TREX-2 complex

       Nuclear pore complex

       Ran-mediated transport factors

       eIF4F and regulatory proteins

         448677 eif4e2; eukaryotic translation initiation factor 4E type 2
         548663 eif4e; eukaryotic translation initiation factor 4E
         548830 eif4e2; eukaryotic translation initiation factor 4E family member 2
         100127761 eif4e1b; eukaryotic translation initiation factor 4E type 1B isoform X1
         496556 eif4a1; eukaryotic initiation factor 4A-I
         100124955 eif4a2; eukaryotic initiation factor 4A-II
         448460 eif4g2; eukaryotic translation initiation factor 4 gamma 2
         100380114 eif4g1; eukaryotic translation initiation factor 4 gamma 1 isoform X1
         100216088 eif4g3; eukaryotic translation initiation factor 4 gamma 3
         448618 eif4b; eukaryotic translation initiation factor 4B
         100125209 eif4h; eukaryotic translation initiation factor 4H
         394958 eif4ebp2; eukaryotic translation initiation factor 4E-binding protein 2
         780398 eif4enif1; eukaryotic translation initiation factor 4E transporter
         548990 angel1; protein angel homolog 1
         100379750 angel2; protein angel homolog 2
         594894 fxr1; fragile X mental retardation syndrome-related protein 1 homolog isoform 1
         100124775 uncharacterized protein LOC100124775
         448049 fmr1; synaptic functional regulator FMR1
         100126215 cyfip2; cytoplasmic FMR1-interacting protein 2
         101734874 cyfip1; cytoplasmic FMR1-interacting protein 1 isoform X1
         100493267 gemin5; gem-associated protein 5 isoform X1
         446220 tacc3; transforming acidic coiled-coil-containing protein 3
         550084 cpeb1; cytoplasmic polyadenylation element-binding protein 1
         100489114 cpeb4; cytoplasmic polyadenylation element-binding protein 4 isoform X2
         100492019 cpeb2; cytoplasmic polyadenylation element-binding protein 2 isoform X2
         548679 cpeb3; cytoplasmic polyadenylation element-binding protein 3
         394804 ddx3x; ATP-dependent RNA helicase DDX3X
         100487831 gigyf2; GRB10-interacting GYF protein 2 isoform X1
         780058 gigyf1; PERQ amino acid-rich with GYF domain-containing protein 1
         448595 pabpc1; polyadenylate-binding protein 1
         448615 pabpc1l; embryonic polyadenylate-binding protein
         100490872 polyadenylate-binding protein 1-B
         548470 pabpc4; polyadenylate-binding protein 4
         100038266 paip1; polyadenylate-binding protein-interacting protein 1
         431678 paip2b; polyadenylate-binding protein-interacting protein 2B
         100038207 skiv2l; helicase SKI2W isoform X2
         100137100 deaf1; deformed epidermal autoregulatory factor 1 homolog isoform X2
         448679 mcts1; malignant T-cell-amplified sequence 1
         448530 denr; density-regulated protein

K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03257 EIF4A; translation initiation factor 4A 
K03257 EIF4A; translation initiation factor 4A 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03258 EIF4B; translation initiation factor 4B 
K24086 EIF4H; translation initiation factor 4H 
K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter 
K18729 ANGEL; protein angel 
K18729 ANGEL; protein angel 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K05749 CYFIP; cytoplasmic FMR1 interacting protein 
K05749 CYFIP; cytoplasmic FMR1 interacting protein 
K13133 GEMIN5; gem associated protein 5 
K14283 TACC3; transforming acidic coiled-coil-containing protein 3 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
K27470 PAIP2; polyadenylate-binding protein-interacting protein 2 
K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
K23041 DEAF1; deformed epidermal autoregulatory factor 1 
K07575 MCTS; malignant T-cell-amplified sequence 
K24272 DENR; density-regulated protein 

       APOBEC1-ACF complex

       Other transport factors

     Surveillance factors

     Factors involved in mRNA localization

     mRNA cycle factors

       Common to processing body (P body) and stress granule

         733797 xrn1; 5'-3' exoribonuclease 1
         448205 ago2; protein argonaute-2
         100302589 ago1; protein argonaute-1
         100486574 ago3; protein argonaute-3 isoform X2
         100495218 ago4; protein argonaute-4 isoform X4
         448677 eif4e2; eukaryotic translation initiation factor 4E type 2
         548663 eif4e; eukaryotic translation initiation factor 4E
         548830 eif4e2; eukaryotic translation initiation factor 4E family member 2
         100127761 eif4e1b; eukaryotic translation initiation factor 4E type 1B isoform X1
         100135270 upf1; regulator of nonsense transcripts 1
         394804 ddx3x; ATP-dependent RNA helicase DDX3X
         780039 ddx6; probable ATP-dependent RNA helicase ddx6
         100490923 mex3b; RNA-binding protein MEX3B
         100487129 mex3a; RNA-binding protein MEX3A
         100144717 mex3d; RNA-binding protein MEX3D
         549821 mex3c; RNA-binding E3 ubiquitin-protein ligase MEX3C
         407942 lsm14a; protein LSM14 homolog A
         595068 lsm14b; protein LSM14 homolog B
         448044 pcbp3; poly(rC)-binding protein 2
         549431 ybx1; nuclease-sensitive element-binding protein 1
         549360 limd1; LIM domain-containing protein 1
         100493332 wtip; Wilms tumor protein 1-interacting protein
         116408872 DNA dC->dU-editing enzyme APOBEC-3A-like
         100491926 mov10; helicase MOV-10 isoform X1
         100494487 putative helicase MOV-10
         493263 pnrc2; proline-rich nuclear receptor coactivator 2
         100492001 tnpo1; transportin-1 isoform X2
         100145499 smg1; serine/threonine-protein kinase SMG1
         780078 smg5; protein SMG5
         100380118 smg6; telomerase-binding protein EST1A
         394870 smg7; protein SMG7
         100127733 zfp36; tristetraprolin
         100125029 zfp36l2; mRNA decay activator protein ZFP36L2
         780215 zfp36l1; zinc finger protein 36, C3H1 type-like 1
         734009 novel zinc finger C-x8-C-x5-C-x3-H type (and similar) protein
         100216028 lin28b; protein lin-28 homolog B
         548523 lin28a; protein lin-28 homolog A isoform 2
         493287 htt; huntingtin isoform X2
         100497558 ipo8; importin-8 isoform X1
         733856 bicc1; protein bicaudal C homolog 1 isoform X1
         100144993 hnrnpa3; heterogeneous nuclear ribonucleoprotein A3
         496507 hnrnpa1; heterogeneous nuclear ribonucleoprotein A1
         549157 prkaca; cAMP-dependent protein kinase catalytic subunit alpha
         100038053 prkacb; cAMP-dependent protein kinase catalytic subunit beta
         116407821 putative protein kinase C delta type homolog
         116407822 putative protein kinase C delta type homolog
         116407825 protein kinase C delta type-like
         108648814 protein kinase C delta type
         100488597 protein kinase C delta type
         105946713 protein kinase C delta type
         101731553 serine/threonine-protein kinase N1
         116411737 protein kinase C delta type-like
         100216225 larp1; la-related protein 1
         100158557 larp1b; la-related protein 1B
         100216248 atxn2l; ataxin-2-like protein
         100490147 atxn2; ataxin-2 isoform X1

K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K11593 ELF2C; eukaryotic translation initiation factor 2C 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27] 
K18749 LSM14; protein LSM14 
K18749 LSM14; protein LSM14 
K13162 PCBP2; poly(rC)-binding protein 2 
K09276 YBX1; Y-box-binding protein 1 
K16682 AJUBA; LIM domain-containing protein 
K16682 AJUBA; LIM domain-containing protein 
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-] 
K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
K18751 PNRC2; proline-rich nuclear receptor coactivator 2 
K18752 TNPO1; transportin-1 
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
K11125 SMG5; protein SMG5 
K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
K14409 SMG7; protein SMG7 
K15308 TTP; tristetraprolin 
K18753 ZFP36L; butyrate response factor 
K18753 ZFP36L; butyrate response factor 
K18753 ZFP36L; butyrate response factor 
K18754 LIN28; protein lin-28 
K18754 LIN28; protein lin-28 
K04533 HD; huntingtin 
K18755 IPO8; importin-8 
K18756 BICC1; protein bicaudal C 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K04345 PKA; protein kinase A [EC:2.7.11.11] 
K18757 LARP1; la-related protein 1 
K18757 LARP1; la-related protein 1 
K23625 ATXN2_2L; ataxin 2/2L 
K23625 ATXN2_2L; ataxin 2/2L 

       P-body specific factors

       Stress granule specific factors

   mRNA degradation factors

 





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Last updated: April 9, 2024