Search BRITE hierarchies
KEGG Orthology (KO) [BR:pon00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism [PATH:pon00562]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway [PATH:pon04015]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04310 Wnt signaling pathway [PATH:pon04310]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04371 Apelin signaling pathway [PATH:pon04371]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04020 Calcium signaling pathway [PATH:pon04020]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04070 Phosphatidylinositol signaling system [PATH:pon04070]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04072 Phospholipase D signaling pathway [PATH:pon04072]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04071 Sphingolipid signaling pathway [PATH:pon04071]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04022 cGMP-PKG signaling pathway [PATH:pon04022]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction [PATH:pon04540]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09150 Organismal Systems
09151 Immune system
04611 Platelet activation [PATH:pon04611]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04613 Neutrophil extracellular trap formation [PATH:pon04613]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04621 NOD-like receptor signaling pathway [PATH:pon04621]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04062 Chemokine signaling pathway [PATH:pon04062]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09152 Endocrine system
04911 Insulin secretion [PATH:pon04911]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04922 Glucagon signaling pathway [PATH:pon04922]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04929 GnRH secretion [PATH:pon04929]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04912 GnRH signaling pathway [PATH:pon04912]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04915 Estrogen signaling pathway [PATH:pon04915]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04921 Oxytocin signaling pathway [PATH:pon04921]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04926 Relaxin signaling pathway [PATH:pon04926]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04935 Growth hormone synthesis, secretion and action [PATH:pon04935]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04918 Thyroid hormone synthesis [PATH:pon04918]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04919 Thyroid hormone signaling pathway [PATH:pon04919]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04928 Parathyroid hormone synthesis, secretion and action [PATH:pon04928]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04916 Melanogenesis [PATH:pon04916]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04924 Renin secretion [PATH:pon04924]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04925 Aldosterone synthesis and secretion [PATH:pon04925]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04927 Cortisol synthesis and secretion [PATH:pon04927]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes [PATH:pon04261]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04270 Vascular smooth muscle contraction [PATH:pon04270]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09154 Digestive system
04970 Salivary secretion [PATH:pon04970]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04971 Gastric acid secretion [PATH:pon04971]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04972 Pancreatic secretion [PATH:pon04972]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04973 Carbohydrate digestion and absorption [PATH:pon04973]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption [PATH:pon04961]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09156 Nervous system
04724 Glutamatergic synapse [PATH:pon04724]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04725 Cholinergic synapse [PATH:pon04725]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04728 Dopaminergic synapse [PATH:pon04728]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04726 Serotonergic synapse [PATH:pon04726]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04720 Long-term potentiation [PATH:pon04720]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04730 Long-term depression [PATH:pon04730]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04723 Retrograde endocannabinoid signaling [PATH:pon04723]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09157 Sensory system
04742 Taste transduction [PATH:pon04742]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04750 Inflammatory mediator regulation of TRP channels [PATH:pon04750]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09159 Environmental adaptation
04713 Circadian entrainment [PATH:pon04713]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer [PATH:pon05200]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09172 Infectious disease: viral
05163 Human cytomegalovirus infection [PATH:pon05163]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09174 Infectious disease: parasitic
05146 Amoebiasis [PATH:pon05146]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05142 Chagas disease [PATH:pon05142]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05143 African trypanosomiasis [PATH:pon05143]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09164 Neurodegenerative disease
05010 Alzheimer disease [PATH:pon05010]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05016 Huntington disease [PATH:pon05016]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05017 Spinocerebellar ataxia [PATH:pon05017]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05022 Pathways of neurodegeneration - multiple diseases [PATH:pon05022]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09166 Cardiovascular disease
05417 Lipid and atherosclerosis [PATH:pon05417]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05415 Diabetic cardiomyopathy [PATH:pon05415]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:pon04933]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04934 Cushing syndrome [PATH:pon04934]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:pon04131]
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Enzymes [BR:pon01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Membrane trafficking [BR:pon04131]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Endocytosis
Macropinocytosis
Phospholipase C
100461961 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
[ BRITE | KEGG2 | KEGG ]