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KEGG Orthology (KO) [BR:ssc00001]
  09130 Environmental Information Processing
    09132 Signal transduction
      04068 FoxO signaling pathway [PATH:ssc04068]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04022 cGMP-PKG signaling pathway [PATH:ssc04022]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04151 PI3K-Akt signaling pathway [PATH:ssc04151]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04152 AMPK signaling pathway [PATH:ssc04152]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04150 mTOR signaling pathway [PATH:ssc04150]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
  09140 Cellular Processes
    09141 Transport and catabolism
      04140 Autophagy - animal [PATH:ssc04140]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
  09150 Organismal Systems
    09152 Endocrine system
      04910 Insulin signaling pathway [PATH:ssc04910]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04923 Regulation of lipolysis in adipocytes [PATH:ssc04923]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04920 Adipocytokine signaling pathway [PATH:ssc04920]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04935 Growth hormone synthesis, secretion and action [PATH:ssc04935]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09155 Excretory system
      04960 Aldosterone-regulated sodium reabsorption [PATH:ssc04960]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09156 Nervous system
      04722 Neurotrophin signaling pathway [PATH:ssc04722]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09149 Aging
      04211 Longevity regulating pathway [PATH:ssc04211]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04213 Longevity regulating pathway - multiple species [PATH:ssc04213]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
  09160 Human Diseases
    09161 Cancer: overview
      05206 MicroRNAs in cancer [PATH:ssc05206]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09164 Neurodegenerative disease
      05010 Alzheimer disease [PATH:ssc05010]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09166 Cardiovascular disease
      05415 Diabetic cardiomyopathy [PATH:ssc05415]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
    09167 Endocrine and metabolic disease
      04930 Type II diabetes mellitus [PATH:ssc04930]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04932 Non-alcoholic fatty liver disease [PATH:ssc04932]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1
      04931 Insulin resistance [PATH:ssc04931]
        100512686 IRS1; insulin receptor substrate 1	K16172 IRS1; insulin receptor substrate 1