Search BRITE hierarchies

KEGG Orthology (KO) [BR:umr00001]
  09130 Environmental Information Processing
    09132 Signal transduction
      04010 MAPK signaling pathway [PATH:umr04010]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04014 Ras signaling pathway [PATH:umr04014]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04015 Rap1 signaling pathway [PATH:umr04015]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04066 HIF-1 signaling pathway [PATH:umr04066]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04068 FoxO signaling pathway [PATH:umr04068]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04072 Phospholipase D signaling pathway [PATH:umr04072]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04022 cGMP-PKG signaling pathway [PATH:umr04022]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04151 PI3K-Akt signaling pathway [PATH:umr04151]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04152 AMPK signaling pathway [PATH:umr04152]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04150 mTOR signaling pathway [PATH:umr04150]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
  09140 Cellular Processes
    09144 Cellular community - eukaryotes
      04520 Adherens junction [PATH:umr04520]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
  09150 Organismal Systems
    09152 Endocrine system
      04910 Insulin signaling pathway [PATH:umr04910]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04923 Regulation of lipolysis in adipocytes [PATH:umr04923]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04913 Ovarian steroidogenesis [PATH:umr04913]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
    09155 Excretory system
      04960 Aldosterone-regulated sodium reabsorption [PATH:umr04960]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
    09149 Aging
      04211 Longevity regulating pathway [PATH:umr04211]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04213 Longevity regulating pathway - multiple species [PATH:umr04213]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
  09160 Human Diseases
    09164 Neurodegenerative disease
      05010 Alzheimer disease [PATH:umr05010]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
    09166 Cardiovascular disease
      05415 Diabetic cardiomyopathy [PATH:umr05415]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
    09167 Endocrine and metabolic disease
      04930 Type II diabetes mellitus [PATH:umr04930]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04932 Non-alcoholic fatty liver disease [PATH:umr04932]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
      04931 Insulin resistance [PATH:umr04931]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
  09180 Brite Hierarchies
    09181 Protein families: metabolism
      01001 Protein kinases [BR:umr01001]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]
    09183 Protein families: signaling and cellular processes
      04090 CD molecules [BR:umr04090]
        103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]

Enzymes [BR:umr01000]
  2. Transferases
    2.7  Transferring phosphorus-containing groups
      2.7.10  Protein-tyrosine kinases
        2.7.10.1  receptor protein-tyrosine kinase
          103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1] 

Protein kinases [BR:umr01001]
  Receptor tyrosine kinases (RTK)
    INSR family [OT]
      103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1] 

CD molecules [BR:umr04090]
  Proteins
    103676308 INSR; insulin receptor	K04527 INSR; insulin receptor [EC:2.7.10.1]