Search BRITE hierarchies
KEGG Orthology (KO) [BR:rno00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism [PATH:rno00562]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway [PATH:rno04015]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04310 Wnt signaling pathway [PATH:rno04310]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04371 Apelin signaling pathway [PATH:rno04371]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04020 Calcium signaling pathway [PATH:rno04020]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04070 Phosphatidylinositol signaling system [PATH:rno04070]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04072 Phospholipase D signaling pathway [PATH:rno04072]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04071 Sphingolipid signaling pathway [PATH:rno04071]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04022 cGMP-PKG signaling pathway [PATH:rno04022]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction [PATH:rno04540]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09150 Organismal Systems
09151 Immune system
04611 Platelet activation [PATH:rno04611]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04613 Neutrophil extracellular trap formation [PATH:rno04613]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04621 NOD-like receptor signaling pathway [PATH:rno04621]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04062 Chemokine signaling pathway [PATH:rno04062]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09152 Endocrine system
04911 Insulin secretion [PATH:rno04911]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04922 Glucagon signaling pathway [PATH:rno04922]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04929 GnRH secretion [PATH:rno04929]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04912 GnRH signaling pathway [PATH:rno04912]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04915 Estrogen signaling pathway [PATH:rno04915]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04921 Oxytocin signaling pathway [PATH:rno04921]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04926 Relaxin signaling pathway [PATH:rno04926]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04935 Growth hormone synthesis, secretion and action [PATH:rno04935]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04918 Thyroid hormone synthesis [PATH:rno04918]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04919 Thyroid hormone signaling pathway [PATH:rno04919]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04928 Parathyroid hormone synthesis, secretion and action [PATH:rno04928]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04916 Melanogenesis [PATH:rno04916]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04924 Renin secretion [PATH:rno04924]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04925 Aldosterone synthesis and secretion [PATH:rno04925]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04927 Cortisol synthesis and secretion [PATH:rno04927]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes [PATH:rno04261]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04270 Vascular smooth muscle contraction [PATH:rno04270]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09154 Digestive system
04970 Salivary secretion [PATH:rno04970]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04971 Gastric acid secretion [PATH:rno04971]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04972 Pancreatic secretion [PATH:rno04972]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04973 Carbohydrate digestion and absorption [PATH:rno04973]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption [PATH:rno04961]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09156 Nervous system
04724 Glutamatergic synapse [PATH:rno04724]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04725 Cholinergic synapse [PATH:rno04725]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04728 Dopaminergic synapse [PATH:rno04728]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04726 Serotonergic synapse [PATH:rno04726]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04720 Long-term potentiation [PATH:rno04720]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04730 Long-term depression [PATH:rno04730]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04723 Retrograde endocannabinoid signaling [PATH:rno04723]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09157 Sensory system
04742 Taste transduction [PATH:rno04742]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04750 Inflammatory mediator regulation of TRP channels [PATH:rno04750]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09159 Environmental adaptation
04713 Circadian entrainment [PATH:rno04713]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer [PATH:rno05200]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09172 Infectious disease: viral
05163 Human cytomegalovirus infection [PATH:rno05163]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09174 Infectious disease: parasitic
05146 Amoebiasis [PATH:rno05146]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05142 Chagas disease [PATH:rno05142]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05143 African trypanosomiasis [PATH:rno05143]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09164 Neurodegenerative disease
05010 Alzheimer disease [PATH:rno05010]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05016 Huntington disease [PATH:rno05016]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05017 Spinocerebellar ataxia [PATH:rno05017]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05022 Pathways of neurodegeneration - multiple diseases [PATH:rno05022]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09166 Cardiovascular disease
05417 Lipid and atherosclerosis [PATH:rno05417]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
05415 Diabetic cardiomyopathy [PATH:rno05415]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:rno04933]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
04934 Cushing syndrome [PATH:rno04934]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:rno04131]
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Enzymes [BR:rno01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Membrane trafficking [BR:rno04131]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Endocytosis
Macropinocytosis
Phospholipase C
24654 Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
[ BRITE | KEGG2 | KEGG ]