Search BRITE hierarchies

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
  L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
    L01 ANTINEOPLASTIC AGENTS
      L01B ANTIMETABOLITES
        L01BA Folic acid analogues
          L01BA01 Methotrexate [DG:DG00681]
            D02115  Methotrexate sodium <US>
    L04 IMMUNOSUPPRESSANTS
      L04A IMMUNOSUPPRESSANTS
        L04AX Other immunosuppressants
          L04AX03 Methotrexate [DG:DG00681]
            D02115  Methotrexate sodium <US>

USP drug classification [BR:br08302]
  Antineoplastics
    Antimetabolites
      Methotrexate [DG:DG00681]
        D02115  Methotrexate sodium
  Immunological Agents
    Immunosuppressants
      Antimetabolites, Antiproliferative
        Methotrexate [DG:DG00681]
          D02115  Methotrexate sodium

Drug groups [BR:br08330]
  Antineoplastic
    DG02018  Antimetabolite
      DG01978  Folic acid analog
        DG01930  Dihydrofolate reductase inhibitor
          DG00681  Methotrexate
            D02115  Methotrexate sodium
  Anti-inflammatory
    DG01985  Disease modifying anti-rheumatic drug (DMARD)
      DG00681  Methotrexate
        D02115  Methotrexate sodium

Drug classes [BR:br08332]
  Antineoplastic
    DG02018  Antimetabolite
      D02115  Methotrexate sodium
  Antirheumatic agent
    DG01985  Disease modifying anti-rheumatic drug (DMARD)
      D02115  Methotrexate sodium

Target-based classification of drugs [BR:br08310]
  Enzymes
    Oxidoreductases (EC1)
      Dihydrofolate reductase [EC:1.5.1.3]
        DHFR [HSA:1719 200895] [KO:K00287]
          D02115  Methotrexate sodium <US>