KEGG pathway modules

Energy metabolism

 Carbon fixation
M00165 Reductive pentose phosphate cycle (Calvin cycle) [PATH: T30128_00710]
M00166 Reductive pentose phosphate cycle, RuBP + CO2 => glyceraldehyde-3P [PATH: T30128_00710]
M00167 Reductive pentose phosphate cycle, glyceraldehyde-3P => RuBP [PATH: T30128_00710]
M00168 CAM (Crassulacean acid metabolism), dark [PATH: T30128_00710]
M00169 CAM (Crassulacean acid metabolism), light [PATH: T30128_00710]
M00170 C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type [PATH: T30128_00710]
M00171 C4-dicarboxylic acid cycle, NAD+ -malic enzyme type [PATH: T30128_00710]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH: T30128_00720]


 Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH: T30128_00910]
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH: T30128_00910]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH: T30128_00910]
M00529 Denitrification, nitrate => nitrogen [PATH: T30128_00910]
M00528 Nitrification, ammonia => nitrite [PATH: T30128_00910]


 Methane metabolism
M00563 Methanogenesis, methylamine => methane [PATH: T30128_00680]
M00562 Methanogenesis, dimethylamine => methane [PATH: T30128_00680]
M00561 Methanogenesis, trimethylamine => methane [PATH: T30128_00680]
M00174 Methane oxidation, methylotroph, methane => CO2 [PATH: T30128_00680]
M00422 Acetyl-CoA pathway, CO2 => acetyl-CoA [PATH: T30128_00680]


 Sulfur metabolism
M00176 Sulfur reduction, sulfate => H2S [PATH: T30128_00920]

Carbohydrate and lipid metabolism

 Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: T30128_00010]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: T30128_00010]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: T30128_00010 T30128_00020]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: T30128_00010 T30128_00020 T30128_00620]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: T30128_00020]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: T30128_00020]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: T30128_00020]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: T30128_00030]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: T30128_00030]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: T30128_00030]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH: T30128_00030]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: T30128_00030 T30128_00230]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: T30128_00030]
M00308 Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glyceraldehyde-3P + pyruvate [PATH: T30128_00030]
M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate => glyceraldehyde + pyruvate [PATH: T30128_00030]


 Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH: T30128_00630]
M00532 Photorespiration [PATH: T30128_00630]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA [PATH: T30128_00640]
M00014 Glucuronate pathway (uronate pathway) [PATH: T30128_00040]
M00061 Uronic acid metabolism [PATH: T30128_00040]
M00081 Pectin degradation [PATH: T30128_00040]


 Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH: T30128_00061]
M00083 Fatty acid biosynthesis, elongation [PATH: T30128_00061]
M00085 Fatty acid biosynthesis, elongation, mitochondria [PATH: T30128_00062]
M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum [PATH: T30128_00062]
M00113 Jasmonic acid biosynthesis [PATH: T30128_00592]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH: T30128_00071]
M00087 beta-Oxidation [PATH: T30128_00071]
M00088 Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone [PATH: T30128_00072]


 Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH: T30128_00561]
M00098 Acylglycerol degradation [PATH: T30128_00561]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH: T30128_00564]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH: T30128_00564]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH: T30128_00564]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: T30128_00564]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: T30128_00562]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: T30128_00562]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: T30128_00562]
M00094 Ceramide biosynthesis [PATH: T30128_00600]
M00066 Lactosylceramide biosynthesis [PATH: T30128_00600]
M00067 Cerebroside and sulfatide biosynthesis [PATH: T30128_00600]
M00099 Sphingosine biosynthesis [PATH: T30128_00600]
M00100 Sphingosine degradation [PATH: T30128_00600]


 Lipopolysaccharide metabolism
M00060 Lipopolysaccharide biosynthesis, KDO2-lipid A [PATH: T30128_00540]
M00063 CMP-KDO biosynthesis [PATH: T30128_00540]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH: T30128_00540]
M00080 Lipopolysaccharide biosynthesis, inner core => outer core => O-antigen [PATH: T30128_00540]


 Sugar metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: T30128_00520]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH: T30128_00520 T30128_00052]


 Glycan metabolism
M00055 N-glycan precursor biosynthesis [PATH: T30128_00510]
M00073 N-glycan precursor trimming [PATH: T30128_00510]
M00074 N-glycan biosynthesis, high-mannose type [PATH: T30128_00510 T30128_00513]
M00075 N-glycan biosynthesis, complex type [PATH: T30128_00510]
M00056 O-glycan biosynthesis, mucin type core [PATH: T30128_00512]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH: T30128_00601]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH: T30128_00601]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH: T30128_00603]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH: T30128_00604]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH: T30128_00563]


 Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH: T30128_00532]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH: T30128_00532]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH: T30128_00534]
M00076 Dermatan sulfate degradation [PATH: T30128_00531]
M00077 Chondroitin sulfate degradation [PATH: T30128_00531]
M00078 Heparan sulfate degradation [PATH: T30128_00531]
M00079 Keratan sulfate degradation [PATH: T30128_00531]


 Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH: T30128_00900]
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH: T30128_00900]


 Sterol biosynthesis
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol [PATH: T30128_00100]
M00103 Cholecalciferol biosynthesis [PATH: T30128_00100]
M00104 Bile acid biosynthesis, cholesterol => cholate [PATH: T30128_00120]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH: T30128_00120]
M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone [PATH: T30128_00140]
M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone [PATH: T30128_00140]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: T30128_00140]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: T30128_00140]


 Other terpenoid biosynthesis
Nucleotide and amino acid metabolism

 Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: T30128_00230]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: T30128_00230]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: T30128_00230]
M00546 Purine degradation, xanthine => urea [PATH: T30128_00230]


 Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH: T30128_00240]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH: T30128_00240]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH: T30128_00240]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH: T30128_00240]


 Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH: T30128_00260]
M00018 Threonine biosynthesis, apartate => homoserine => threonine [PATH: T30128_00260]
M00555 Betaine biosynthesis, choline => betaine [PATH: T30128_00260]


 Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH: T30128_00270]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH: T30128_00270]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH: T30128_00270]
M00034 Methionine salvage pathway [PATH: T30128_00270]
M00035 Methionine degradation [PATH: T30128_00270]


 Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH: T30128_00290]
M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH: T30128_00290]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH: T30128_00290]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH: T30128_00290]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH: T30128_00280]


 Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: T30128_00300]
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH: T30128_00300]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH: T30128_00300]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH: T30128_00300]
M00030 Lysine biosynthesis, 2-oxoglutarate => 2-aminoadipate => lysine [PATH: T30128_00300]
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate [PATH: T30128_00300]
M00031 Lysine biosynthesis, 2-aminoadipate => lysine [PATH: T30128_00300]
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH: T30128_00310]


 Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH: T30128_00330]
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH: T30128_00330]
M00029 Urea cycle [PATH: T30128_00330]


 Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH: T30128_00340]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH: T30128_00340]


 Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: T30128_00400]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: T30128_00400]
M00024 Phenylalanine biosynthesis, chorismate => phenylalanine [PATH: T30128_00400]
M00025 Tyrosine biosynthesis, chorismate => tyrosine [PATH: T30128_00400]
M00040 Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine [PATH: T30128_00400]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: T30128_00350]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: T30128_00350]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: T30128_00350]
M00545 Trans-cinnamate degradation, trans-cinnamate => 2-oxopent-4-enoate + fumarate [PATH: T30128_00360]
M00350 Capsaicin biosynthesis, L-Phenylalanine => Capsaicin [PATH: T30128_00360]
M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin [PATH: T30128_00380]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: T30128_00380]


 Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH: T30128_00250]
M00047 Creatine pathway [PATH: T30128_00330]


 Cofactor and vitamin biosynthesis
M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P [PATH: T30128_00730]
M00125 Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD [PATH: T30128_00740]
M00124 Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P [PATH: T30128_00750]
M00115 NAD biosynthesis, aspartate => NAD [PATH: T30128_00760]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: T30128_00770]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: T30128_00770]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH: T30128_00780]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: T30128_00780]
M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin [PATH: T30128_00780]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH: T30128_00780]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: T30128_00790 T30128_00670]
M00121 Heme biosynthesis, glutamate => protoheme/siroheme [PATH: T30128_00860]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH: T30128_00040 T30128_00053]
M00114 Ascorbate biosynthesis, plants, glucose-6P => ascorbate [PATH: T30128_00010 T30128_00051 T30128_00053]
M00112 Tocopherol biosynthesis [PATH: T30128_00130]
M00122 Cobalamin biosynthesis, cobinamide => cobalamin [PATH: T30128_00860]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone [PATH: T30128_00130]
M00128 Ubiquinone biosynthesis, eukaryotes, chorismate => ubiquinone [PATH: T30128_00130]
M00116 Menaquinone biosynthesis, chorismate => menaquinone [PATH: T30128_00130]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH: T30128_00480]


 Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH: T30128_00330]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH: T30128_00330]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH: T30128_00330]
M00136 GABA biosynthesis, prokaryotes, putrescine => GABA [PATH: T30128_00330]


 Phenylpropanoid and flavonoid biosynthesis
M00039 Lignin biosynthesis, cinnamate => lignin [PATH: T30128_00940]
M00137 Flavonoid biosynthesis, 4-coumaroyl-CoA => naringenin => apigenin [PATH: T30128_00941]
M00138 Flavonoid biosynthesis, naringenin => pelargonidin [PATH: T30128_00941]


 Alkaloid and other secondary metabolite biosynthesis
M00139 Morphine biosynthesis, dopamine => morphine [PATH: T30128_00950]
M00033 Ectoine biosynthesis [PATH: T30128_00260]

Secondary metabolism

 Aromatics degradataion
M00538 Toluene degradation, toluene => benzoate [PATH: T30128_00623]
M00537 Xylene degradation, xylene => methylbenzoate [PATH: T30128_00622]
M00419 Cymene degradation, p-cymene => p-cumate [PATH: T30128_00622]
M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH: T30128_00362 T30128_00623]
M00548 Benzene degradation, benzene => catechol [PATH: T30128_00362]
M00551 Benzoate degradation, benzoate => catechol [PATH: T30128_00362 T30128_00622]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH: T30128_00362]
M00569 Catechol meta-cleavage, catechol => pyruvate + acetaldehyde [PATH: T30128_00362 T30128_00622]
M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate [PATH: T30128_00622]
M00543 Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate [PATH: T30128_00621]
M00544 Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate [PATH: T30128_00621]
M00418 Toluene degradation, anaerobic, toluene => benzoyl-CoA [PATH: T30128_00623]
M00541 Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA [PATH: T30128_00362]
M00540 Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA [PATH: T30128_00362]
M00534 Naphthalene degradataion, naphthalene => salicylate [PATH: T30128_00626]

Energy metabolism

 Photosynthesis
M00161 Photosystem II [PATH: T30128_00195]
M00162 Cytochrome b6f complex [PATH: T30128_00195]
M00163 Photosystem I [PATH: T30128_00195]
M00164 ATP synthase [PATH: T30128_00195]


 ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH: T30128_00190]
M00145 NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria [PATH: T30128_00190]
M00142 NADH:ubiquinone oxidoreductase, mitochondria [PATH: T30128_00190]
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH: T30128_00190]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH: T30128_00190]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH: T30128_00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH: T30128_00190]
M00150 Fumarate reductase, prokaryotes [PATH: T30128_00190]
M00148 Succinate dehydrogenase (ubiquinone) [PATH: T30128_00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH: T30128_00190]
M00152 Cytochrome bc1 complex [PATH: T30128_00190]
M00154 Cytochrome c oxidase [PATH: T30128_00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH: T30128_00190]
M00153 Cytochrome d ubiquinol oxidase [PATH: T30128_00190]
M00417 Cytochrome o ubiquinol oxidase [PATH: T30128_00190]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH: T30128_00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH: T30128_00190]

Carbohydrate and lipid metabolism

 Carbohydrate metabolism
M00310 Pyruvate:ferredoxin oxidoreductase [PATH: T30128_00620]
M00311 2-oxoglutarate:ferredoxin oxidoreductase [PATH: T30128_00020]
M00312 2-oxoisovalerate:ferredoxin oxidoreductase [PATH: T30128_00280]
M00313 indolepyruvate:ferredoxin oxidoreductase


 Glycan metabolism
M00072 Oligosaccharyltransferase [PATH: T30128_00510]

Genetic information processing

 DNA polymerase
M00260 DNA polymerase III complex, bacteria [BR:ko03032 ko03400][PATH: T30128_03030 T30128_03430 T30128_03440]
M00264 DNA polymerase II complex, archaea [BR:ko03032]
M00261 DNA polymerase alpha / primase complex [BR:ko03032][PATH: T30128_03030]
M00262 DNA polymerase delta complex [BR:ko03032 ko03400][PATH: T30128_03030 T30128_03410 T30128_03420]
M00263 DNA polymerase epsilon complex [BR:ko03032 ko03400][PATH: T30128_03030]
M00293 DNA polymerase zeta complex [BR:ko03400][PATH: T30128_03460]
M00294 DNA polymerase gamma complex [BR:ko03032]


 Replication system
M00284 Origin recognition complex [BR:ko03032][PATH: T30128_04110 T30128_04111 T30128_04113]
M00285 MCM complex [BR:ko03032][PATH: T30128_03030 T30128_04110 T30128_04111 T30128_04113]
M00286 GINS complex [BR:ko03032]
M00288 RPA complex [BR:ko03032 ko03400][PATH: T30128_03030 T30128_03420 T30128_03430 T30128_03440]
M00289 RF-C complex [BR:ko03032 ko03400][PATH: T30128_03030 T30128_03420 T30128_03430]
M00424 Shelterin complex [BR:ko03032]


 Repair system
M00296 BER complex [BR:ko03400][PATH: T30128_03410]
M00290 Holo-TFIIH complex [BR:ko03021 ko03400][PATH: T30128_03420]
M00291 MRN complex [BR:ko03032 ko03400][PATH: T30128_03440]
M00292 MRX complex [BR:ko03400][PATH: T30128_03440 T30128_03450]
M00297 DNA-PK complex [BR:ko03032 ko03400][PATH: T30128_03450 T30128_04110]
M00295 BRCA1-associated genome surveillance complex (BASC) [BR:ko03400][PATH: T30128_03430 T30128_03440 T30128_03460]
M00413 FA core complex [BR:ko03400][PATH: T30128_03460]
M00414 Bloom's syndrome complex [BR:ko03400][PATH: T30128_03460]


 RNA polymerase
M00183 RNA polymerase, bacteria [BR:ko03021 ko03400][PATH: T30128_03020]
M00184 RNA polymerase, archaea [BR:ko03021][PATH: T30128_03020]
M00180 RNA polymerase II, eukaryotes [BR:ko03021 ko03400][PATH: T30128_03020 T30128_05016]
M00181 RNA polymerase III, eukaryotes [BR:ko03021][PATH: T30128_03020 T30128_04623]
M00182 RNA polymerase I, eukaryotes [BR:ko03021][PATH: T30128_03020]


 Spliceosome
M00351 Spliceosome, U1-snRNP [BR:ko03041][PATH: T30128_03040]
M00352 Spliceosome, U2-snRNP [BR:ko03041][PATH: T30128_03040]
M00354 Spliceosome, U4/U6.U5 tri-snRNP [BR:ko03041][PATH: T30128_03040]
M00396 Lsm 2-8 complex [BR:ko03041][PATH: T30128_03040 T30128_03018]
M00397 Lsm 1-7 complex [PATH: T30128_03018]
M00398 Sm core complex [BR:ko03032 ko03041][PATH: T30128_03040]
M00399 Cap binding complex [BR:ko03041][PATH: T30128_03013 T30128_03015 T30128_03040 T30128_03040]


 RNA processing
M00425 H/ACA ribonucleoprotein complex [BR:ko03032 ko03009][PATH: T30128_03008]
M00426 Survival motor neuron (SMN) complex [BR:ko03041][PATH: T30128_03013]
M00427 Nuclear pore complex [PATH: T30128_03013]
M00428 eIF4F complex [BR:ko03012][PATH: T30128_03013]
M00430 Exon junction complex (EJC) [BR:ko03041][PATH: T30128_03013 T30128_03015 T30128_03040]
M00405 THC complex [BR:ko03041][PATH: T30128_03040 T30128_03013]
M00406 TREX complex [BR:ko03041][PATH: T30128_03013 T30128_03040]
M00390 Exosome, archaea [PATH: T30128_03018]
M00391 Exosome, eukaryotes [PATH: T30128_03018]
M00392 Ski complex [PATH: T30128_03018]
M00393 TRAMP complex [PATH: T30128_03018]
M00394 RNA degradosome [PATH: T30128_03018]
M00395 Decapping complex [PATH: T30128_03018]


 Ribosome

 Proteasome
M00337 Immunoproteasome [BR:ko03051][PATH: T30128_03050]


 Ubiquitin system
M00379 SCF-MET30 complex [BR:ko04121][PATH: T30128_04120 T30128_04111]
M00380 SCF-BTRC complex [BR:ko04121][PATH: T30128_04120 T30128_04114 T30128_04310 T30128_04710]
M00381 SCF-SKP2 complex [BR:ko04121][PATH: T30128_04120 T30128_04110 T30128_05168]
M00382 SCF-FBS complex [BR:ko04121][PATH: T30128_04120 T30128_04141]
M00407 SCF-CDC4 complex [BR:ko04121][PATH: T30128_04120 T30128_04111]
M00411 SCF-GRR1 complex [BR:ko04121][PATH: T30128_04120 T30128_04111]
M00383 ECV complex [BR:ko04121][PATH: T30128_04120 T30128_05211]
M00384 Cul3-SPOP complex [BR:ko04121][PATH: T30128_04120]
M00385 Cul4-DDB1-DDB2 complex [BR:ko04121 ko03400][PATH: T30128_04120 T30128_03420]
M00386 Cul4-DDB1-CSA complex [BR:ko04121 ko03400][PATH: T30128_04120 T30128_03420]
M00387 SCF-FBW7 complex [BR:ko04121][PATH: T30128_04120]
M00388 ECS complex [BR:ko04121][PATH: T30128_04120]
M00389 APC/C complex [BR:ko04121 ko03036][PATH: T30128_04120 T30128_04110 T30128_04114 T30128_04914 T30128_04111 T30128_04113]


 Protein processing
M00400 p97-Ufd1-Npl4 complex [PATH: T30128_04141]
M00401 Sec61 complex [BR:ko02044][PATH: T30128_03060 T30128_04141 T30128_04145 T30128_05110]
M00402 Translocon-associated protein (TRAP) complex [PATH: T30128_04141]
M00403 HRD1/SEL1 ERAD complex [PATH: T30128_04141]
M00404 COPII complex [PATH: T30128_04141]
M00408 ESCRT-0 complex [PATH: T30128_04144]
M00409 ESCRT-I complex [PATH: T30128_04144]
M00410 ESCRT-II complex [PATH: T30128_04144]
M00412 ESCRT-III complex [PATH: T30128_04144]

Environmental information processing

 Mineral and organic ion transport system
M00185 Sulfate transport system [BR:ko02000][PATH: T30128_02010]
M00189 Molybdate transport system [BR:ko02000][PATH: T30128_02010]
M00423 Molybdate/tungstate transport system [BR:ko02000][PATH: T30128_02010]
M00186 Tungstate transport system [BR:ko02000][PATH: T30128_02010]
M00438 Nitrate/nitrite transport system [BR:ko02000][PATH: T30128_02010]
M00321 Bicarbonate transport system [BR:ko02000][PATH: T30128_02010]
M00188 NitT/TauT family transport system [BR:ko02000]
M00435 Taurine transport system [BR:ko02000][PATH: T30128_02010]
M00436 Sulfonate transport system [BR:ko02000][PATH: T30128_02010]
M00437 Phthalate transport system [BR:ko02000][PATH: T30128_02010]
M00190 Iron(III) transport system [BR:ko02000][PATH: T30128_02010]
M00191 Thiamine transport system [BR:ko02000][PATH: T30128_02010]
M00299 Spermidine/putrescine transport system [BR:ko02000][PATH: T30128_02010]
M00300 Putrescine transport system [BR:ko02000][PATH: T30128_02010]
M00193 Putative spermidine/putrescine transport system [BR:ko02000]
M00301 Mannopine transport system [BR:ko02000][PATH: T30128_02010]
M00302 2-Aminoethylphosphonate transport system [BR:ko02000][PATH: T30128_02010]
M00208 Glycine betaine/proline transport system [BR:ko02000][PATH: T30128_02010]
M00209 Osmoprotectant transport system [BR:ko02000][PATH: T30128_02010]
M00442 Putative hydroxymethylpyrimidine transport system [BR:ko02000][PATH: T30128_02010]
M00192 Putative thiamine transport system [BR:ko02000]


 Saccharide and polyol transport system
M00194 Maltose/maltodextrin transport system [BR:ko02000][PATH: T30128_02010]
M00195 Maltooligosaccharide transport system [BR:ko02000][PATH: T30128_02010]
M00196 Multiple sugar transport system [BR:ko02000][PATH: T30128_02010]
M00201 alpha-Glucoside transport system [BR:ko02000][PATH: T30128_02010]
M00203 Glucose/arabinose transport system [BR:ko02000][PATH: T30128_02010]
M00204 Trehalose/maltose transport system [BR:ko02000][PATH: T30128_02010]
M00205 N-Acetylglucosamine transport system [BR:ko02000][PATH: T30128_02010]
M00206 Cellobiose transport system [BR:ko02000][PATH: T30128_02010]
M00213 L-Arabinose transport system [BR:ko02000][PATH: T30128_02010]
M00199 L-Arabinose/lactose transport system [BR:ko02000][PATH: T30128_02010]
M00202 Oligogalacturonide transport system [BR:ko02000][PATH: T30128_02010]
M00214 Methyl-galactoside transport system [BR:ko02000][PATH: T30128_02010]
M00215 D-Xylose transport system [BR:ko02000][PATH: T30128_02010]
M00216 Multiple sugar transport system [BR:ko02000][PATH: T30128_02010]
M00217 D-Allose transport system [BR:ko02000][PATH: T30128_02010]
M00218 Fructose transport system [BR:ko02000][PATH: T30128_02010]
M00219 AI-2 transport system [BR:ko02000][PATH: T30128_02010]
M00220 Rhamnose transport system [BR:ko02000][PATH: T30128_02010]
M00212 Ribose transport system [BR:ko02000][PATH: T30128_02010]
M00197 Putative fructooligosaccharide transport system [BR:ko02000]
M00198 Putative sn-glycerol-phosphate transport system [BR:ko02000][PATH: T30128_02010]
M00200 Putative sorbitol/mannitol transport system [BR:ko02000][PATH: T30128_02010]
M00491 Putative arabinogalactan oligomer transport system [BR:ko02000][PATH: T30128_02010]
M00207 Putative multiple sugar transport system [BR:ko02000]
M00221 Putative simple sugar transport system [BR:ko02000]
M00210 Putative ABC transport system [BR:ko02000]
M00211 Putative ABC transport system [BR:ko02000]


 Phosphate and amino acid transport system
M00222 Phosphate transport system [BR:ko02000][PATH: T30128_02010]
M00223 Phosphonate transport system [BR:ko02000][PATH: T30128_02010]
M00225 Lysine/arginine/ornithine transport system [BR:ko02000][PATH: T30128_02010]
M00226 Histidine transport system [BR:ko02000][PATH: T30128_02010]
M00227 Glutamine transport system [BR:ko02000][PATH: T30128_02010]
M00229 Arginine transport system [BR:ko02000][PATH: T30128_02010]
M00230 Glutamate/aspartate transport system [BR:ko02000][PATH: T30128_02010]
M00231 Octopine/nopaline transport system [BR:ko02000][PATH: T30128_02010]
M00232 General L-amino acid transport system [BR:ko02000][PATH: T30128_02010]
M00233 Glutamate transport system [BR:ko02000][PATH: T30128_02010]
M00234 Cystine transport system [BR:ko02000][PATH: T30128_02010]
M00585 L-Cystine transport system [BR:ko02000][PATH: T30128_02010]
M00235 Arginine/ornithine transport system [BR:ko02000][PATH: T30128_02010]
M00237 Branched-chain amino acid transport system [BR:ko02000][PATH: T30128_02010]
M00322 Neutral amino acid transport system [BR:ko02000][PATH: T30128_02010]
M00323 Urea transport system [BR:ko02000][PATH: T30128_02010]
M00238 D-Methionine transport system [BR:ko02000][PATH: T30128_02010]
M00224 Putative phosphonate transport system [BR:ko02000][PATH: T30128_02010]
M00228 Putative glutamine transport system [BR:ko02000][PATH: T30128_02010]
M00586 Putative amino-acid transport system [BR:ko02000][PATH: T30128_02010]
M00236 Putative polar amino acid transport system [BR:ko02000]


 Peptide and nickel transport system
M00439 Oligopeptide transport system [BR:ko02000][PATH: T30128_02010]
M00324 Dipeptide transport system [BR:ko02000][PATH: T30128_02010]
M00566 Dipeptide transport system, Firmicutes [BR:ko02000][PATH: T30128_02010]
M00440 Nickel transport system [BR:ko02000][PATH: T30128_02010]
M00239 Peptides/nickel transport system [BR:ko02000][PATH: T30128_02010]


 Metallic cation, iron-siderophore and vitamin B12 transport system
M00240 Iron complex transport system [BR:ko02000][PATH: T30128_02010]
M00241 Vitamin B12 transport system [BR:ko02000][PATH: T30128_02010]
M00316 Manganese transport system [BR:ko02000][PATH: T30128_02010 T30128_02020]
M00242 Zinc transport system [BR:ko02000][PATH: T30128_02010]
M00318 Iron/zinc/copper transport system [BR:ko02000][PATH: T30128_02010]
M00317 Manganese/iron transport system [BR:ko02000][PATH: T30128_02010]
M00319 Manganese/zinc/iron transport system [BR:ko02000][PATH: T30128_02010]
M00243 Manganese/iron transport system [BR:ko02000]
M00245 Cobalt transport system [BR:ko02000][PATH: T30128_02010]
M00246 Nickel transport system [BR:ko02000][PATH: T30128_02010]
M00581 Biotin transport system [BR:ko02000][PATH: T30128_02010]
M00582 Energy-coupling factor transport system [BR:ko02000][PATH: T30128_02010]
M00244 Putative zinc/manganese transport system [BR:ko02000]
M00247 Putative ABC transport system [BR:ko02000]


 ABC-2 type and other transport systems
M00298 Multidrug/hemolysin transport system [BR:ko02000][PATH: T30128_02010]
M00249 Capsular polysaccharide transport system [BR:ko02000][PATH: T30128_02010]
M00250 Lipopolysaccharide transport system [BR:ko02000][PATH: T30128_02010]
M00320 Lipopolysaccharide export system [BR:ko02000][PATH: T30128_02010]
M00251 Teichoic acid transport system [BR:ko02000][PATH: T30128_02010]
M00252 Lipooligosaccharide transport system [BR:ko02000][PATH: T30128_02010]
M00253 Sodium transport system [BR:ko02000][PATH: T30128_02010]
M00583 Putative peptide transport system [BR:ko02000][PATH: T30128_02010]
M00257 Hemin transport system [BR:ko02000][PATH: T30128_02010]
M00314 Bacitracin transport system [BR:ko02000][PATH: T30128_02010 T30128_02020]
M00224 Fluoroquinolones transport system [BR:ko02000][PATH: T30128_02010]
M00255 Lipoprotein-releasing system [BR:ko02000][PATH: T30128_02010]
M00584 Acetoin utilization transport system [BR:ko02000][PATH: T30128_02010]
M00259 Heme transport system [BR:ko02000][PATH: T30128_02010]
M00256 Cell division transport system [BR:ko02000][PATH: T30128_02010]
M00315 Uncharacterized ABC transport system [BR:ko02000][PATH: T30128_02020]
M00248 Putative antibiotic transport system [BR:ko02000][PATH: T30128_02010]
M00258 Putative ABC transport system [BR:ko02000]
M00254 ABC-2 type transport system [BR:ko02000]


 Phosphotransferase system (PTS)
M00265 PTS system, glucose-specific II component [BR:ko02000][PATH: T30128_00010 T30128_02060]
M00267 PTS system, N-acetylglucosamine-specific II component [BR:ko02000][PATH: T30128_00520 T30128_02060]
M00266 PTS system, maltose and glucose-specific II component [BR:ko02000][PATH: T30128_00010 T30128_00500 T30128_02060]
M00282 PTS system, D-glucosamine-specific II component [BR:ko02000][PATH: T30128_00520 T30128_02060]
M00269 PTS system, sucrose-specific II component [BR:ko02000][PATH: T30128_00500 T30128_02060]
M00271 PTS system, beta-glucosides-specific II component [BR:ko02000][PATH: T30128_02060]
M00272 PTS system, arbutin-, cellobiose-, and salicin-specific II component [BR:ko02000][PATH: T30128_00010 T30128_02060]
M00270 PTS system, trehalose-specific II component [BR:ko02000][PATH: T30128_00500 T30128_02060]
M00303 PTS system, N-acetylmuramic acid-specific II component [BR:ko02000][PATH: T30128_02060]
M00268 PTS system, arbutin-like II component [BR:ko02000][PATH: T30128_00010 T30128_02060]
M00273 PTS system, fructose-specific II component [BR:ko02000][PATH: T30128_00051 T30128_02060]
M00306 PTS system, fructose-specific II-like component [BR:ko02000]
M00274 PTS system, mannitol-specific II component [BR:ko02000][PATH: T30128_00051 T30128_02060]
M00305 PTS system, 2-O-A-mannosyl-D-glycerate-specific II component [BR:ko02000][PATH: T30128_02060]
M00281 PTS system, lactose-specific II component [BR:ko02000][PATH: T30128_00052 T30128_02060]
M00275 PTS system, cellobiose-specific II component [BR:ko02000][PATH: T30128_02060]
M00280 PTS system, glucitol/sorbitol-specific II component [BR:ko02000][PATH: T30128_00051 T30128_02060]
M00279 PTS system, galactitol-specific II component [BR:ko02000][PATH: T30128_00052 T30128_02060]
M00276 PTS system, mannose-specific II component [BR:ko02000][PATH: T30128_00051 T30128_02060]
M00304 PTS system, fructose-specific II component [BR:ko02000][PATH: T30128_02060]
M00278 PTS system, sorbose-specific II component [BR:ko02000][PATH: T30128_00051 T30128_02060]
M00277 PTS system, N-acetylgalactosamine-specific II component [BR:ko02000][PATH: T30128_00052 T30128_02060]
M00287 PTS system, galactosamine-specific II component [BR:ko02000][PATH: T30128_00052 T30128_02060]
M00283 PTS system, ascorbate-specific II component [BR:ko02000][PATH: T30128_00053 T30128_02060]


 Bacterial secretion system
M00325 alpha-Hemolysin/cyclolysin transport system [BR:ko02000][PATH: T30128_02010 T30128_03070]
M00326 RTX toxin transport system [BR:ko02044]
M00327 S-Layer protein transport system [BR:ko02044]
M00328 Hemophore/metalloprotease transport system [BR:ko02044]
M00329 Multiple protein transport system [BR:ko02044]
M00330 Adhesin protein transport system [BR:ko02044]
M00571 AlgE-type Mannuronan C-5-Epimerase transport system [BR:ko02044]
M00339 RaxAB-RaxC type I secretion system [BR:ko02044][PATH: T30128_04626]
M00331 Type II general secretion system [BR:ko02044][PATH: T30128_03070]
M00332 Type III secretion system [BR:ko02044][PATH: T30128_03070]
M00333 Type IV secretion system [BR:ko02044][PATH: T30128_03070]
M00334 Type VI secretion system [BR:ko02044][PATH: T30128_03070]
M00335 Sec (secretion) system [BR:ko02044][PATH: T30128_03070]
M00336 Twin-arginine translocation (Tat) system [BR:ko02044][PATH: T30128_03070]
M00429 Competence-related DNA transformation transporter [BR:ko02044]

Metabolism

 Aminoacyl tRNA

 Nucleotide sugar
Environmental information processing

 Two-component regulatory system
M00434 PhoR-PhoB (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00443 SenX3-RegX3 (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00444 PhoQ-PhoP (magnesium transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00445 EnvZ-OmpR (osmotic stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00446 RstB-RstA two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00447 CpxA-CpxR (envelope stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00448 CssS-CssR (secretion stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00449 CreC-CreB (phosphate regulation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00450 BaeS-BaeR (envelope stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00451 BasS-BasR (antimicrobial peptide resistance) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00452 CusS-CusR (copper tolerance) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00453 QseC-QseB (quorum sensing) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00454 KdpD-KdpE (potassium transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00455 TorS-TorR (trimethylamine N-oxide respiration) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00456 ArcB-ArcA (anoxic redox control) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00457 TctE-TctD (tricarboxylic acid transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00458 ResE-ResD (aerobic and anaerobic respiration) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00459 VicK-VicR (cell wall metabolism) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00460 MprB-MprA (maintenance of persistent infection) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00461 MtrB-MtrA (osmotic stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00462 PrrB-PrrA (intracellular multiplication) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00463 TrcS-TrcR two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00464 NrsS-NrsR (nickel tolerance) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00465 ManS-ManR (manganese homeostasis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00466 NblS-NblR (photosynthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00467 SasA-RpaAB (circadian timing mediating) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00468 SaeS-SaeR (staphylococcal virulence regulation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00469 BceS-BceR (bacitracin transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00470 YxdK-YxdJ (antimicrobial peptide response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00471 NarX-NarL (nitrate respiration) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00472 NarQ-NarP (nitrate respiration) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00473 UhpB-UhpA (hexose phosphates uptake) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00474 RcsC-RcsD-RcsB (capsule synthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00475 BarA-UvrY (central carbon metabolism) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00476 ComP-ComA (competence) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00477 EvgS-EvgA (acid and drug tolerance) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00478 DegS-DegU (multicellular behavior control) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00479 DesK-DesR (membrane lipid fluidity regulation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00480 VraS-VraR (cell-wall peptidoglycan synthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00481 LiaS-LiaR (cell wall stress response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00482 DevS-DevR (redox response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00483 NreB-NreC (dissimilatory nitrate/nitrite reduction) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00484 YdfH-YdfI two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00485 KinABCDE-Spo0FA (sporulation control) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00486 CitA-CitB (citrate fermentation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00487 CitS-CitT (magnesium-citrate transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00488 DcuS-DcuR (aerobic C4-dicarboxylate metabolism) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00489 DctS-DctR (C4-dicarboxylate transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00490 MalK-MalR (malate transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00492 LytS-LytR (autolysis and cell wall metabolism) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00493 AlgZ-AlgR (alginate production) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00494 NatK-NatR (sodium extrusion) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00495 AgrC-AgrA (exoprotein synthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00496 ComD-ComE (competence) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00497 GlnL-GlnG (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00498 NtrY-NtrX (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00499 HydH-HydG (metal tolerance) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00500 AtoS-AtoC (complexed poly-(R)-3-hydroxybutyrate biosynthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00501 PilS-PilR (type 4 fimbriae synthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00502 GlrK-GlrR (amino sugar metabolism) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00503 PgtB-PgtA (phosphoglycerate transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00504 DctB-DctD (C4-dicarboxylate transport) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00505 KinB-AlgB (alginate production) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00506 CheA-CheYBV (chemotaxis) two-component regulatory system [BR:ko02022 ko02030 ko02035][PATH: T30128_02020 T30128_02030]
M00507 ChpA-ChpB/PilGH (chemosensory) two-component regulatory system [BR:ko02022 ko02035][PATH: T30128_02020]
M00508 PixL-PixGH (positive phototaxis) two-component regulatory system [BR:ko02022 ko02035][PATH: T30128_02020]
M00509 WspE-WspRF (chemosensory) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00510 Cph1-Rcp1 (light response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00511 PleC-PleD (cell fate control) two-component regulatory system [BR:ko02022][PATH: T30128_02020 T30128_04112]
M00512 CckA-CtrA/CpdR (cell cycle control) two-component regulatory system [BR:ko02022][PATH: T30128_02020 T30128_04112]
M00513 LuxQN/CqsS-LuxU-LuxO (quorum sensing) two-component regulatory system [BR:ko02022][PATH: T30128_02020 T30128_05111]
M00514 TtrS-TtrR (tetrathionate respiration) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00515 FlrB-FlrC (polar flagellar synthesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020 T30128_05111]
M00516 SLN1-YPD1-SSK1/SKN7 (osmosensing) two-component regulatory system [BR:ko02022][PATH: T30128_02020 T30128_04011]
M00517 RpfC-RpfG (cell-to-cell signaling) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00518 GlnK-GlnL (glutamine utilization) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00519 YesM-YesN two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00520 ChvG-ChvI (acidity sensing) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00521 CiaH-CiaR (stress resistance and pathogenesis) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00522 SalK-SalR two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00523 RegB-RegA (redox response) two-component regulatory system [BR:ko02022][PATH: T30128_02020]
M00524 FixL-FixJ (nitrogen fixation) two-component regulatory system [BR:ko02022][PATH: T30128_02020]

Genotypic signature

 Metabolic capacity
M00557 Methanogenesis [PATH: T30128_00680]
M00558 Methane oxidation by pMMO [PATH: T30128_00680]
M00559 Methane oxidation by sMMO [PATH: T30128_00680]
M00560 Ammonia oxidation [PATH: T30128_00910]


 Pathogenicity
M00363 EHEC pathogenicity signature, Shiga toxin [PATH: T30128_05130 T30128_05131]
M00542 EHEC/EPEC pathogenicity signature, T3SS and effectors [PATH: T30128_05130]
M00574 Pertussis pathogenicity signature 1, pertussis toxin [PATH: T30128_05133]
M00575 Pertussis pathogenicity signature 2, T1SS [PATH: T30128_05133]
M00564 Helicobacter pylori pathogenicity signature, cagA pathogenicity island [PATH: T30128_05120]