KEGG   Escherichia coli O26:H11 11368 (EHEC)

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KEGG Modules

Pathway module
    Energy metabolism
       Carbon fixation
       Nitrogen metabolism
        M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH: eoj00910]
       Methane metabolism
       Sulfur metabolism
    Carbohydrate and lipid metabolism
       Central carbohydrate metabolism
        M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: eoj00010]
        M00002 Glycolysis, core module involving three-carbon compounds [PATH: eoj00010]
        M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: eoj00010 eoj00020]
        M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: eoj00010 eoj00020 eoj00620]
        M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: eoj00020]
        M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: eoj00020]
        M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: eoj00020]
        M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: eoj00030]
        M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: eoj00030]
        M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: eoj00030]
        M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: eoj00030 eoj00230]
        M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: eoj00030]
       Other carbohydrate metabolism
       Fatty acid metabolism
       Lipid metabolism
        M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: eoj00564]
       Lipopolysaccharide metabolism
       Sugar metabolism
       Glycan metabolism
       Glycosaminoglycan metabolism
       Terpenoid backbone biosynthesis
        M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH: eoj00900]
        M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH: eoj00900]
       Sterol biosynthesis
       Other terpenoid biosynthesis
    Nucleotide and amino acid metabolism
       Purine metabolism
        M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: eoj00230]
        M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: eoj00230]
        M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: eoj00230]
       Pyrimidine metabolism
        M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH: eoj00240]
        M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH: eoj00240]
        M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH: eoj00240]
       Serine and threonine metabolism
        M00020 Serine biosynthesis, glycerate-3P => serine [PATH: eoj00260]
        M00018 Threonine biosynthesis, apartate => homoserine => threonine [PATH: eoj00260]
        M00555 Betaine biosynthesis, choline => betaine [PATH: eoj00260]
       Cysteine and methionine metabolism
        M00021 Cysteine biosynthesis, serine => cysteine [PATH: eoj00270]
        M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH: eoj00270]
       Branched-chain amino acid metabolism
        M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH: eoj00290]
        M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH: eoj00290]
        M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH: eoj00290]
       Lysine metabolism
        M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: eoj00300]
       Arginine and proline metabolism
        M00015 Proline biosynthesis, glutamate => proline [PATH: eoj00330]
        M00028 Ornithine biosynthesis, glutamate => ornithine [PATH: eoj00330]
       Histidine metabolism
       Aromatic amino acid metabolism
        M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: eoj00400]
        M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: eoj00400]
        M00024 Phenylalanine biosynthesis, chorismate => phenylalanine [PATH: eoj00400]
        M00025 Tyrosine biosynthesis, chorismate => tyrosine [PATH: eoj00400]
        M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: eoj00350]
        M00545 Trans-cinnamate degradation, trans-cinnamate => 2-oxopent-4-enoate + fumarate [PATH: eoj00360]
       Other amino acid metabolism
       Cofactor and vitamin biosynthesis
        M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P [PATH: eoj00730]
        M00124 Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P [PATH: eoj00750]
        M00115 NAD biosynthesis, aspartate => NAD [PATH: eoj00760]
        M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: eoj00770]
        M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: eoj00770]
        M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH: eoj00780]
        M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: eoj00780]
        M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: eoj00790 eoj00670]
        M00121 Heme biosynthesis, glutamate => protoheme/siroheme [PATH: eoj00860]
        M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH: eoj00053]
        M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone [PATH: eoj00130]
        M00118 Glutathione biosynthesis, glutamate => glutathione [PATH: eoj00480]
       Polyamine biosynthesis
        M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH: eoj00330]
        M00136 GABA biosynthesis, prokaryotes, putrescine => GABA [PATH: eoj00330]
       Phenylpropanoid and flavonoid biosynthesis
       Alkaloid and other secondary metabolite biosynthesis
    Secondary metabolism
       Aromatics degradataion
Structural complex
    Energy metabolism Carbohydrate and lipid metabolism
       Carbohydrate metabolism
       Glycan metabolism
    Genetic information processing
       DNA polymerase
       Replication system
       Repair system
       RNA polymerase
        M00183 RNA polymerase, bacteria [BR:ko03021 ko03400][PATH: eoj03020]
       Spliceosome
       RNA processing
       Ribosome
       Proteasome
       Ubiquitin system
       Protein processing
    Environmental information processing
       Mineral and organic ion transport system
        M00185 Sulfate transport system [BR:ko02000][PATH: eoj02010]
        M00189 Molybdate transport system [BR:ko02000][PATH: eoj02010]
        M00435 Taurine transport system [BR:ko02000][PATH: eoj02010]
        M00436 Sulfonate transport system [BR:ko02000][PATH: eoj02010]
        M00191 Thiamine transport system [BR:ko02000][PATH: eoj02010]
        M00299 Spermidine/putrescine transport system [BR:ko02000][PATH: eoj02010]
        M00300 Putrescine transport system [BR:ko02000][PATH: eoj02010]
        M00193 Putative spermidine/putrescine transport system [BR:ko02000]
        M00208 Glycine betaine/proline transport system [BR:ko02000][PATH: eoj02010]
        M00209 Osmoprotectant transport system [BR:ko02000][PATH: eoj02010]
        M00192 Putative thiamine transport system [BR:ko02000]
       Saccharide and polyol transport system
        M00213 L-Arabinose transport system [BR:ko02000][PATH: eoj02010]
        M00214 Methyl-galactoside transport system [BR:ko02000][PATH: eoj02010]
        M00215 D-Xylose transport system [BR:ko02000][PATH: eoj02010]
        M00219 AI-2 transport system [BR:ko02000][PATH: eoj02010]
        M00212 Ribose transport system [BR:ko02000][PATH: eoj02010]
        M00198 Putative sn-glycerol-phosphate transport system [BR:ko02000][PATH: eoj02010]
        M00491 Putative arabinogalactan oligomer transport system [BR:ko02000][PATH: eoj02010]
        M00221 Putative simple sugar transport system [BR:ko02000]
        M00210 Putative ABC transport system [BR:ko02000]
        M00211 Putative ABC transport system [BR:ko02000]
       Phosphate and amino acid transport system
       Peptide and nickel transport system
       Metallic cation, iron-siderophore and vitamin B12 transport system
       ABC-2 type and other transport systems
        M00320 Lipopolysaccharide export system [BR:ko02000][PATH: eoj02010]
        M00255 Lipoprotein-releasing system [BR:ko02000][PATH: eoj02010]
        M00259 Heme transport system [BR:ko02000][PATH: eoj02010]
        M00256 Cell division transport system [BR:ko02000][PATH: eoj02010]
        M00248 Putative antibiotic transport system [BR:ko02000][PATH: eoj02010]
        M00258 Putative ABC transport system [BR:ko02000]
        M00254 ABC-2 type transport system [BR:ko02000]
       Phosphotransferase system (PTS)
       Bacterial secretion system
Functional set
    Metabolism
       Aminoacyl tRNA
       Nucleotide sugar
    Environmental information processing
       Two-component regulatory system
        M00434 PhoR-PhoB (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00444 PhoQ-PhoP (magnesium transport) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00445 EnvZ-OmpR (osmotic stress response) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00446 RstB-RstA two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00447 CpxA-CpxR (envelope stress response) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00449 CreC-CreB (phosphate regulation) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00450 BaeS-BaeR (envelope stress response) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00451 BasS-BasR (antimicrobial peptide resistance) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00452 CusS-CusR (copper tolerance) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00453 QseC-QseB (quorum sensing) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00454 KdpD-KdpE (potassium transport) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00455 TorS-TorR (trimethylamine N-oxide respiration) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00456 ArcB-ArcA (anoxic redox control) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00471 NarX-NarL (nitrate respiration) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00472 NarQ-NarP (nitrate respiration) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00473 UhpB-UhpA (hexose phosphates uptake) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00474 RcsC-RcsD-RcsB (capsule synthesis) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00475 BarA-UvrY (central carbon metabolism) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00477 EvgS-EvgA (acid and drug tolerance) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00486 CitA-CitB (citrate fermentation) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00488 DcuS-DcuR (aerobic C4-dicarboxylate metabolism) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00497 GlnL-GlnG (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00499 HydH-HydG (metal tolerance) two-component regulatory system [BR:ko02022][PATH: eoj02020]
        M00502 GlrK-GlrR (amino sugar metabolism) two-component regulatory system [BR:ko02022][PATH: eoj02020]
Signature module
    Genotypic signature
       Metabolic capacity
       Pathogenicity
        M00363 EHEC pathogenicity signature, Shiga toxin [PATH: eoj05130]
        M00542 EHEC/EPEC pathogenicity signature, T3SS and effectors [PATH: eoj05130]

KEGG2 PATHWAY BRITE GENES GENOME LIGAND DISEASE DRUG