KEGG Modules

Energy metabolism

 Carbon fixation

 Nitrogen metabolism

 Methane metabolism

 Sulfur metabolism
M00176 Sulfur reduction, sulfate => H2S [PATH: mmc00920]

Carbohydrate and lipid metabolism

 Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: mmc00010]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: mmc00010]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: mmc00010 mmc00020]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: mmc00010 mmc00020 mmc00620]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: mmc00020]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: mmc00030]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: mmc00030]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: mmc00030]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: mmc00030 mmc00230]


 Other carbohydrate metabolism

 Fatty acid metabolism
M00083 Fatty acid biosynthesis, elongation [PATH: mmc00061]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH: mmc00071]
M00087 beta-Oxidation [PATH: mmc00071]


 Lipid metabolism
M00098 Acylglycerol degradation [PATH: mmc00561]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: mmc00564]


 Lipopolysaccharide metabolism

 Sugar metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: mmc00520]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH: mmc00500]


 Glycan metabolism

 Glycosaminoglycan metabolism

 Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH: mmc00900]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH: mmc00900]


 Sterol biosynthesis

 Other terpenoid biosynthesis
Nucleotide and amino acid metabolism

 Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: mmc00230]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: mmc00230]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: mmc00230]


 Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH: mmc00240]


 Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH: mmc00260]
M00018 Threonine biosynthesis, apartate => homoserine => threonine [PATH: mmc00260]
M00555 Betaine biosynthesis, choline => betaine [PATH: mmc00260]


 Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH: mmc00270]
M00035 Methionine degradation [PATH: mmc00270]


 Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH: mmc00290]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH: mmc00290]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH: mmc00290]


 Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: mmc00300]


 Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH: mmc00330]
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH: mmc00330]


 Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH: mmc00340]


 Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: mmc00400]


 Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH: mmc00250]


 Cofactor and vitamin biosynthesis
M00115 NAD biosynthesis, aspartate => NAD [PATH: mmc00760]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: mmc00770]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: mmc00770]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: mmc00780]
M00121 Heme biosynthesis, glutamate => protoheme/siroheme [PATH: mmc00860]


 Polyamine biosynthesis

 Phenylpropanoid and flavonoid biosynthesis

 Alkaloid and other secondary metabolite biosynthesis
M00033 Ectoine biosynthesis [PATH: mmc00260]

Secondary metabolism

 Aromatics degradataion

Energy metabolism

 Photosynthesis

 ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH: mmc00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH: mmc00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH: mmc00190]
M00153 Cytochrome d ubiquinol oxidase [PATH: mmc00190]
M00157 F-type ATPase, bacteria [PATH: mmc00190]

Carbohydrate and lipid metabolism

 Carbohydrate metabolism

 Glycan metabolism
Genetic information processing

 DNA polymerase
M00260 DNA polymerase III complex, bacteria [BR:ko03032 ko03400][PATH: mmc03030 mmc03430 mmc03440]


 Replication system

 Repair system

 RNA polymerase
M00183 RNA polymerase, bacteria [BR:ko03021 ko03400][PATH: mmc03020]


 Spliceosome

 RNA processing

 Ribosome
M00178 Ribosome, bacteria [BR:ko03011][PATH: mmc03010]


 Proteasome
M00342 Bacterial proteasome [BR:ko03051][PATH: mmc03050]


 Ubiquitin system

 Protein processing
Environmental information processing

 Mineral and organic ion transport system
M00185 Sulfate transport system [BR:ko02000][PATH: mmc02010]
M00189 Molybdate transport system [BR:ko02000][PATH: mmc02010]
M00188 NitT/TauT family transport system [BR:ko02000]
M00435 Taurine transport system [BR:ko02000][PATH: mmc02010]
M00190 Iron(III) transport system [BR:ko02000][PATH: mmc02010]
M00299 Spermidine/putrescine transport system [BR:ko02000][PATH: mmc02010]
M00209 Osmoprotectant transport system [BR:ko02000][PATH: mmc02010]


 Saccharide and polyol transport system
M00212 Ribose transport system [BR:ko02000][PATH: mmc02010]
M00207 Putative multiple sugar transport system [BR:ko02000]
M00210 Putative ABC transport system [BR:ko02000]


 Phosphate and amino acid transport system
M00222 Phosphate transport system [BR:ko02000][PATH: mmc02010]
M00233 Glutamate transport system [BR:ko02000][PATH: mmc02010]
M00234 Cystine transport system [BR:ko02000][PATH: mmc02010]
M00237 Branched-chain amino acid transport system [BR:ko02000][PATH: mmc02010]
M00323 Urea transport system [BR:ko02000][PATH: mmc02010]
M00224 Putative phosphonate transport system [BR:ko02000][PATH: mmc02010]
M00236 Putative polar amino acid transport system [BR:ko02000]


 Peptide and nickel transport system
M00239 Peptides/nickel transport system [BR:ko02000][PATH: mmc02010]


 Metallic cation, iron-siderophore and vitamin B12 transport system
M00245 Cobalt transport system [BR:ko02000][PATH: mmc02010]
M00581 Biotin transport system [BR:ko02000][PATH: mmc02010]
M00582 Energy-coupling factor transport system [BR:ko02000][PATH: mmc02010]
M00244 Putative zinc/manganese transport system [BR:ko02000]


 ABC-2 type and other transport systems
M00250 Lipopolysaccharide transport system [BR:ko02000][PATH: mmc02010]
M00224 Fluoroquinolones transport system [BR:ko02000][PATH: mmc02010]
M00256 Cell division transport system [BR:ko02000][PATH: mmc02010]
M00248 Putative antibiotic transport system [BR:ko02000][PATH: mmc02010]


 Phosphotransferase system (PTS)
M00273 PTS system, fructose-specific II component [BR:ko02000][PATH: mmc00051 mmc02060]


 Bacterial secretion system
M00335 Sec (secretion) system [BR:ko02044][PATH: mmc03070]
M00336 Twin-arginine translocation (Tat) system [BR:ko02044][PATH: mmc03070]

Metabolism

 Aminoacyl tRNA
M00360 Aminoacyl-tRNA biosynthesis, prokaryotes [PATH: mmc00970]


 Nucleotide sugar
Environmental information processing

 Two-component regulatory system
M00443 SenX3-RegX3 (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: mmc02020]
M00454 KdpD-KdpE (potassium transport) two-component regulatory system [BR:ko02022][PATH: mmc02020]
M00460 MprB-MprA (maintenance of persistent infection) two-component regulatory system [BR:ko02022][PATH: mmc02020]
M00461 MtrB-MtrA (osmotic stress response) two-component regulatory system [BR:ko02022][PATH: mmc02020]
M00462 PrrB-PrrA (intracellular multiplication) two-component regulatory system [BR:ko02022][PATH: mmc02020]

Genotypic signature

 Pathogenicity