KEGG Modules

Energy metabolism

 Carbon fixation

 Nitrogen metabolism

 Methane metabolism

 Sulfur metabolism
M00176 Sulfur reduction, sulfate => H2S [PATH: oce00920]

Carbohydrate and lipid metabolism

 Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH: oce00010]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: oce00010 oce00020 oce00620]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: oce00020]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: oce00020]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: oce00020]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: oce00030]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: oce00030 oce00230]


 Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH: oce00630]


 Fatty acid metabolism

 Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: oce00564]


 Lipopolysaccharide metabolism
M00060 Lipopolysaccharide biosynthesis, KDO2-lipid A [PATH: oce00540]
M00063 CMP-KDO biosynthesis [PATH: oce00540]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH: oce00540]


 Sugar metabolism

 Glycan metabolism

 Glycosaminoglycan metabolism

 Terpenoid backbone biosynthesis

 Sterol biosynthesis

 Other terpenoid biosynthesis
Nucleotide and amino acid metabolism

 Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: oce00230]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: oce00230]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: oce00230]


 Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH: oce00240]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH: oce00240]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH: oce00240]


 Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH: oce00260]
M00018 Threonine biosynthesis, apartate => homoserine => threonine [PATH: oce00260]
M00555 Betaine biosynthesis, choline => betaine [PATH: oce00260]


 Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH: oce00270]


 Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH: oce00290]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH: oce00290]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH: oce00290]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH: oce00280]


 Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: oce00300]


 Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH: oce00330]
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH: oce00330]


 Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH: oce00340]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH: oce00340]


 Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: oce00400]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: oce00400]
M00024 Phenylalanine biosynthesis, chorismate => phenylalanine [PATH: oce00400]
M00025 Tyrosine biosynthesis, chorismate => tyrosine [PATH: oce00400]


 Other amino acid metabolism

 Cofactor and vitamin biosynthesis
M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P [PATH: oce00730]
M00115 NAD biosynthesis, aspartate => NAD [PATH: oce00760]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: oce00770]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: oce00770]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: oce00780]
M00121 Heme biosynthesis, glutamate => protoheme/siroheme [PATH: oce00860]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone [PATH: oce00130]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH: oce00480]


 Polyamine biosynthesis
M00136 GABA biosynthesis, prokaryotes, putrescine => GABA [PATH: oce00330]


 Phenylpropanoid and flavonoid biosynthesis

 Alkaloid and other secondary metabolite biosynthesis
M00033 Ectoine biosynthesis [PATH: oce00260]

Secondary metabolism

 Aromatics degradataion
M00551 Benzoate degradation, benzoate => catechol [PATH: oce00362 oce00622]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH: oce00362]

Energy metabolism

 Photosynthesis

 ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH: oce00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH: oce00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH: oce00190]
M00153 Cytochrome d ubiquinol oxidase [PATH: oce00190]
M00417 Cytochrome o ubiquinol oxidase [PATH: oce00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH: oce00190]
M00157 F-type ATPase, bacteria [PATH: oce00190]

Carbohydrate and lipid metabolism

 Carbohydrate metabolism

 Glycan metabolism
Genetic information processing

 DNA polymerase
M00260 DNA polymerase III complex, bacteria [BR:ko03032 ko03400][PATH: oce03030 oce03430 oce03440]


 Replication system

 Repair system

 RNA polymerase
M00183 RNA polymerase, bacteria [BR:ko03021 ko03400][PATH: oce03020]


 Spliceosome

 RNA processing
M00394 RNA degradosome [PATH: oce03018]


 Ribosome
M00178 Ribosome, bacteria [BR:ko03011][PATH: oce03010]


 Proteasome

 Ubiquitin system

 Protein processing
Environmental information processing

 Mineral and organic ion transport system
M00185 Sulfate transport system [BR:ko02000][PATH: oce02010]
M00189 Molybdate transport system [BR:ko02000][PATH: oce02010]
M00190 Iron(III) transport system [BR:ko02000][PATH: oce02010]
M00299 Spermidine/putrescine transport system [BR:ko02000][PATH: oce02010]
M00300 Putrescine transport system [BR:ko02000][PATH: oce02010]
M00193 Putative spermidine/putrescine transport system [BR:ko02000]
M00209 Osmoprotectant transport system [BR:ko02000][PATH: oce02010]


 Saccharide and polyol transport system
M00212 Ribose transport system [BR:ko02000][PATH: oce02010]
M00210 Putative ABC transport system [BR:ko02000]


 Phosphate and amino acid transport system
M00222 Phosphate transport system [BR:ko02000][PATH: oce02010]
M00223 Phosphonate transport system [BR:ko02000][PATH: oce02010]
M00229 Arginine transport system [BR:ko02000][PATH: oce02010]
M00232 General L-amino acid transport system [BR:ko02000][PATH: oce02010]
M00235 Arginine/ornithine transport system [BR:ko02000][PATH: oce02010]
M00237 Branched-chain amino acid transport system [BR:ko02000][PATH: oce02010]
M00238 D-Methionine transport system [BR:ko02000][PATH: oce02010]
M00586 Putative amino-acid transport system [BR:ko02000][PATH: oce02010]


 Peptide and nickel transport system
M00439 Oligopeptide transport system [BR:ko02000][PATH: oce02010]
M00324 Dipeptide transport system [BR:ko02000][PATH: oce02010]
M00239 Peptides/nickel transport system [BR:ko02000][PATH: oce02010]


 Metallic cation, iron-siderophore and vitamin B12 transport system
M00240 Iron complex transport system [BR:ko02000][PATH: oce02010]
M00241 Vitamin B12 transport system [BR:ko02000][PATH: oce02010]
M00242 Zinc transport system [BR:ko02000][PATH: oce02010]
M00317 Manganese/iron transport system [BR:ko02000][PATH: oce02010]


 ABC-2 type and other transport systems
M00249 Capsular polysaccharide transport system [BR:ko02000][PATH: oce02010]
M00320 Lipopolysaccharide export system [BR:ko02000][PATH: oce02010]
M00255 Lipoprotein-releasing system [BR:ko02000][PATH: oce02010]
M00259 Heme transport system [BR:ko02000][PATH: oce02010]
M00256 Cell division transport system [BR:ko02000][PATH: oce02010]
M00248 Putative antibiotic transport system [BR:ko02000][PATH: oce02010]
M00258 Putative ABC transport system [BR:ko02000]


 Phosphotransferase system (PTS)

 Bacterial secretion system
M00330 Adhesin protein transport system [BR:ko02044]
M00331 Type II general secretion system [BR:ko02044][PATH: oce03070]
M00335 Sec (secretion) system [BR:ko02044][PATH: oce03070]
M00336 Twin-arginine translocation (Tat) system [BR:ko02044][PATH: oce03070]

Metabolism

 Aminoacyl tRNA
M00360 Aminoacyl-tRNA biosynthesis, prokaryotes [PATH: oce00970]


 Nucleotide sugar
Environmental information processing

 Two-component regulatory system
M00434 PhoR-PhoB (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00452 CusS-CusR (copper tolerance) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00454 KdpD-KdpE (potassium transport) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00456 ArcB-ArcA (anoxic redox control) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00457 TctE-TctD (tricarboxylic acid transport) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00475 BarA-UvrY (central carbon metabolism) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00497 GlnL-GlnG (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00502 GlrK-GlrR (amino sugar metabolism) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00504 DctB-DctD (C4-dicarboxylate transport) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00514 TtrS-TtrR (tetrathionate respiration) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00515 FlrB-FlrC (polar flagellar synthesis) two-component regulatory system [BR:ko02022][PATH: oce02020]
M00523 RegB-RegA (redox response) two-component regulatory system [BR:ko02022][PATH: oce02020]

Genotypic signature

 Pathogenicity