KEGG Modules

Energy metabolism

 Carbon fixation

 Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH: sjp00910]


 Methane metabolism

 Sulfur metabolism
Carbohydrate and lipid metabolism

 Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH: sjp00010]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: sjp00010 sjp00020]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: sjp00010 sjp00020 sjp00620]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: sjp00020]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: sjp00020]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: sjp00020]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: sjp00030]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: sjp00030 sjp00230]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: sjp00030]


 Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH: sjp00630]


 Fatty acid metabolism
M00083 Fatty acid biosynthesis, elongation [PATH: sjp00061]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH: sjp00071]


 Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH: sjp00564]


 Lipopolysaccharide metabolism

 Sugar metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: sjp00520]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH: sjp00500]


 Glycan metabolism

 Glycosaminoglycan metabolism

 Terpenoid backbone biosynthesis

 Sterol biosynthesis

 Other terpenoid biosynthesis
Nucleotide and amino acid metabolism

 Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH: sjp00230]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH: sjp00230]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH: sjp00230]


 Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH: sjp00240]


 Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH: sjp00260]
M00018 Threonine biosynthesis, apartate => homoserine => threonine [PATH: sjp00260]


 Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH: sjp00270]


 Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH: sjp00290]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH: sjp00290]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH: sjp00290]


 Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH: sjp00300]


 Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH: sjp00330]
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH: sjp00330]


 Histidine metabolism

 Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: sjp00400]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: sjp00400]
M00024 Phenylalanine biosynthesis, chorismate => phenylalanine [PATH: sjp00400]
M00040 Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine [PATH: sjp00400]


 Other amino acid metabolism

 Cofactor and vitamin biosynthesis
M00115 NAD biosynthesis, aspartate => NAD [PATH: sjp00760]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: sjp00770]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: sjp00780]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH: sjp00480]


 Polyamine biosynthesis

 Phenylpropanoid and flavonoid biosynthesis

 Alkaloid and other secondary metabolite biosynthesis
Secondary metabolism

 Aromatics degradataion
M00548 Benzene degradation, benzene => catechol [PATH: sjp00362]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH: sjp00362]
M00569 Catechol meta-cleavage, catechol => pyruvate + acetaldehyde [PATH: sjp00362 sjp00622]

Energy metabolism

 Photosynthesis

 ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH: sjp00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH: sjp00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH: sjp00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH: sjp00190]
M00417 Cytochrome o ubiquinol oxidase [PATH: sjp00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH: sjp00190]
M00157 F-type ATPase, bacteria [PATH: sjp00190]

Carbohydrate and lipid metabolism

 Carbohydrate metabolism

 Glycan metabolism
Genetic information processing

 DNA polymerase
M00260 DNA polymerase III complex, bacteria [BR:ko03032 ko03400][PATH: sjp03030 sjp03430 sjp03440]


 Replication system

 Repair system

 RNA polymerase
M00183 RNA polymerase, bacteria [BR:ko03021 ko03400][PATH: sjp03020]


 Spliceosome

 RNA processing

 Ribosome
M00178 Ribosome, bacteria [BR:ko03011][PATH: sjp03010]


 Proteasome

 Ubiquitin system

 Protein processing
Environmental information processing

 Mineral and organic ion transport system
M00189 Molybdate transport system [BR:ko02000][PATH: sjp02010]
M00438 Nitrate/nitrite transport system [BR:ko02000][PATH: sjp02010]
M00188 NitT/TauT family transport system [BR:ko02000]
M00436 Sulfonate transport system [BR:ko02000][PATH: sjp02010]


 Saccharide and polyol transport system
M00210 Putative ABC transport system [BR:ko02000]


 Phosphate and amino acid transport system
M00222 Phosphate transport system [BR:ko02000][PATH: sjp02010]
M00323 Urea transport system [BR:ko02000][PATH: sjp02010]


 Peptide and nickel transport system

 Metallic cation, iron-siderophore and vitamin B12 transport system
M00240 Iron complex transport system [BR:ko02000][PATH: sjp02010]


 ABC-2 type and other transport systems
M00320 Lipopolysaccharide export system [BR:ko02000][PATH: sjp02010]
M00255 Lipoprotein-releasing system [BR:ko02000][PATH: sjp02010]
M00259 Heme transport system [BR:ko02000][PATH: sjp02010]
M00256 Cell division transport system [BR:ko02000][PATH: sjp02010]
M00248 Putative antibiotic transport system [BR:ko02000][PATH: sjp02010]
M00258 Putative ABC transport system [BR:ko02000]
M00254 ABC-2 type transport system [BR:ko02000]


 Phosphotransferase system (PTS)

 Bacterial secretion system
M00325 alpha-Hemolysin/cyclolysin transport system [BR:ko02000][PATH: sjp02010 sjp03070]
M00330 Adhesin protein transport system [BR:ko02044]
M00331 Type II general secretion system [BR:ko02044][PATH: sjp03070]
M00333 Type IV secretion system [BR:ko02044][PATH: sjp03070]
M00335 Sec (secretion) system [BR:ko02044][PATH: sjp03070]
M00336 Twin-arginine translocation (Tat) system [BR:ko02044][PATH: sjp03070]

Metabolism

 Aminoacyl tRNA
M00360 Aminoacyl-tRNA biosynthesis, prokaryotes [PATH: sjp00970]


 Nucleotide sugar
Environmental information processing

 Two-component regulatory system
M00434 PhoR-PhoB (phosphate starvation response) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00497 GlnL-GlnG (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00498 NtrY-NtrX (nitrogen regulation) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00512 CckA-CtrA/CpdR (cell cycle control) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00520 ChvG-ChvI (acidity sensing) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00523 RegB-RegA (redox response) two-component regulatory system [BR:ko02022][PATH: sjp02020]
M00524 FixL-FixJ (nitrogen fixation) two-component regulatory system [BR:ko02022][PATH: sjp02020]

Genotypic signature

 Metabolic capacity

 Pathogenicity