Drug metabolism - other enzymes
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Reference pathway
Reference pathway (KO)
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Homo sapiens (human)
Homo sapiens (human) + Disease/drug
Pan troglodytes (chimpanzee)
Pan paniscus (bonobo)
Gorilla gorilla gorilla (western lowland gorilla)
Pongo abelii (Sumatran orangutan)
Nomascus leucogenys (northern white-cheeked gibbon)
Macaca mulatta (rhesus monkey)
Macaca fascicularis (crab-eating macaque)
Chlorocebus sabaeus (green monkey)
Rhinopithecus roxellana (golden snub-nosed monkey)
Callithrix jacchus (white-tufted-ear marmoset)
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Mus musculus (mouse)
Rattus norvegicus (rat)
Cricetulus griseus (Chinese hamster)
Nannospalax galili (Upper Galilee mountains blind mole rat)
Heterocephalus glaber (naked mole rat)
Oryctolagus cuniculus (rabbit)
Tupaia chinensis (Chinese tree shrew)
Canis familiaris (dog)
Ailuropoda melanoleuca (giant panda)
Ursus maritimus (polar bear)
Felis catus (domestic cat)
Panthera tigris altaica (Amur tiger)
Acinonyx jubatus (cheetah)
Bos taurus (cow)
Bos mutus (wild yak)
Pantholops hodgsonii (chiru)
Capra hircus (goat)
Ovis aries (sheep)
Sus scrofa (pig)
Camelus ferus (Wild Bactrian camel)
Balaenoptera acutorostrata scammoni (minke whale)
Lipotes vexillifer (Yangtze River dolphin)
Equus caballus (horse)
Myotis brandtii (Brandt's bat)
Myotis davidii
Hipposideros armiger (great roundleaf bat)
Pteropus alecto (black flying fox)
Loxodonta africana (African savanna elephant)
Monodelphis domestica (opossum)
Sarcophilus harrisii (Tasmanian devil)
Ornithorhynchus anatinus (platypus)
Gallus gallus (chicken)
Meleagris gallopavo (turkey)
Coturnix japonica (Japanese quail)
Anas platyrhynchos (mallard)
Taeniopygia guttata (zebra finch)
Geospiza fortis (medium ground-finch)
Ficedula albicollis (collared flycatcher)
Pseudopodoces humilis (Tibetan ground-tit)
Corvus cornix (hooded crow)
Falco peregrinus (peregrine falcon)
Falco cherrug (Saker falcon)
Columba livia (rock pigeon)
Apteryx australis mantelli (brown kiwi)
Alligator sinensis (Chinese alligator)
Alligator mississippiensis (American alligator)
Pelodiscus sinensis (Chinese soft-shelled turtle)
Chelonia mydas (green sea turtle)
Chrysemys picta (western painted turtle)
Anolis carolinensis (green anole)
Python bivittatus (Burmese python)
Gekko japonicus
Xenopus laevis (African clawed frog)
Xenopus tropicalis (western clawed frog)
Danio rerio (zebrafish)
Ictalurus punctatus (channel catfish)
Takifugu rubripes (torafugu)
Tetraodon nigroviridis (spotted green pufferfish)
Larimichthys crocea (large yellow croaker)
Maylandia zebra (zebra mbuna)
Oryzias latipes (Japanese medaka)
Xiphophorus maculatus (southern platyfish)
Salmo salar (Atlantic salmon)
Latimeria chalumnae (coelacanth)
Callorhinchus milii (elephant shark)
Branchiostoma floridae (Florida lancelet)
Ciona intestinalis (sea squirt)
Strongylocentrotus purpuratus (purple sea urchin)
Saccoglossus kowalevskii (acorn worm)
Drosophila melanogaster (fruit fly)
Drosophila pseudoobscura pseudoobscura
Drosophila ananassae
Drosophila erecta
Drosophila persimilis
Drosophila sechellia
Drosophila simulans
Drosophila willistoni
Drosophila yakuba
Drosophila grimshawi
Drosophila mojavensis
Drosophila virilis
Musca domestica (house fly)
Anopheles gambiae (mosquito)
Aedes aegypti (yellow fever mosquito)
Culex quinquefasciatus (southern house mosquito)
Apis mellifera (honey bee)
Bombus impatiens (common eastern bumble bee)
Bombus terrestris (buff-tailed bumblebee)
Solenopsis invicta (red fire ant)
Acromyrmex echinatior (Panamanian leafcutter ant)
Harpegnathos saltator (Jerdon's jumping ant)
Camponotus floridanus (Florida carpenter ant)
Nasonia vitripennis (jewel wasp)
Tribolium castaneum (red flour beetle)
Bombyx mori (domestic silkworm)
Danaus plexippus (monarch butterfly)
Plutella xylostella (diamondback moth)
Acyrthosiphon pisum (pea aphid)
Pediculus humanus corporis (human body louse)
Daphnia pulex (common water flea)
Ixodes scapularis (black-legged tick)
Caenorhabditis elegans (nematode)
Caenorhabditis briggsae
Brugia malayi (filaria)
Loa loa (eye worm)
Trichinella spiralis
Helobdella robusta
Lottia gigantea (owl limpet)
Crassostrea gigas (Pacific oyster)
Octopus bimaculoides
Schistosoma mansoni
Nematostella vectensis (sea anemone)
Acropora digitifera (stony coral)
Hydra vulgaris
Trichoplax adhaerens
Amphimedon queenslandica (sponge)
184%
150%
122%
100%
82%
67%
55%
Drug metabolism - other enzymes
Drug metabolism - other enzymes
