Drug metabolism - other enzymes
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Reference pathway
Reference pathway (KO)
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Homo sapiens (human)
Homo sapiens (human) + Disease/drug
Pan troglodytes (chimpanzee)
Pan paniscus (bonobo)
Gorilla gorilla gorilla (western lowland gorilla)
Pongo abelii (Sumatran orangutan)
Macaca mulatta (rhesus monkey)
Macaca fascicularis (crab-eating macaque)
Mus musculus (mouse)
Rattus norvegicus (rat)
Cricetulus griseus (Chinese hamster)
Heterocephalus glaber (naked mole rat)
Tupaia chinensis (Chinese tree shrew)
Canis familiaris (dog)
Ailuropoda melanoleuca (giant panda)
Felis catus (domestic cat)
Panthera tigris altaica (Amur tiger)
Bos taurus (cow)
Bos mutus (wild yak)
Pantholops hodgsonii (chiru)
Capra hircus (goat)
Sus scrofa (pig)
Camelus ferus (Wild Bactrian camel)
Balaenoptera acutorostrata scammoni (minke whale)
Lipotes vexillifer (Yangtze River dolphin)
Equus caballus (horse)
Myotis brandtii (Brandt's bat)
Myotis davidii
Pteropus alecto (black flying fox)
Monodelphis domestica (opossum)
Sarcophilus harrisii (Tasmanian devil)
Ornithorhynchus anatinus (platypus)
Gallus gallus (chicken)
Meleagris gallopavo (turkey)
Taeniopygia guttata (zebra finch)
Ficedula albicollis (collared flycatcher)
Pseudopodoces humilis (Tibetan ground-tit)
Anas platyrhynchos (mallard)
Falco peregrinus (peregrine falcon)
Falco cherrug (Saker falcon)
Columba livia (rock pigeon)
Alligator sinensis (Chinese alligator)
Alligator mississippiensis (American alligator)
Pelodiscus sinensis (Chinese soft-shelled turtle)
Chelonia mydas (green sea turtle)
Anolis carolinensis (green anole)
Python bivittatus (Burmese python)
Xenopus laevis (African clawed frog)
Xenopus tropicalis (western clawed frog)
Danio rerio (zebrafish)
Takifugu rubripes (torafugu)
Maylandia zebra (zebra mbuna)
Oryzias latipes (Japanese medaka)
Xiphophorus maculatus (southern platyfish)
Latimeria chalumnae (coelacanth)
Callorhinchus milii (elephant shark)
Branchiostoma floridae (Florida lancelet)
Ciona intestinalis (sea squirt)
Strongylocentrotus purpuratus (purple sea urchin)
Drosophila melanogaster (fruit fly)
Drosophila pseudoobscura pseudoobscura
Drosophila ananassae
Drosophila erecta
Drosophila persimilis
Drosophila sechellia
Drosophila simulans
Drosophila willistoni
Drosophila yakuba
Drosophila grimshawi
Drosophila mojavensis
Drosophila virilis
Anopheles gambiae (mosquito)
Aedes aegypti (yellow fever mosquito)
Culex quinquefasciatus (southern house mosquito)
Apis mellifera (honey bee)
Nasonia vitripennis (jewel wasp)
Tribolium castaneum (red flour beetle)
Bombyx mori (domestic silkworm)
Acyrthosiphon pisum (pea aphid)
Pediculus humanus corporis (human body louse)
Ixodes scapularis (black-legged tick)
Caenorhabditis elegans (nematode)
Caenorhabditis briggsae
Brugia malayi (filaria)
Loa loa (eye worm)
Trichinella spiralis
Schistosoma mansoni
Nematostella vectensis (sea anemone)
Hydra vulgaris
Trichoplax adhaerens
Amphimedon queenslandica (sponge)
184%
150%
122%
100%
82%
67%
55%
Drug metabolism - other enzymes
Drug metabolism - other enzymes
