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Dioxygenases in aromatic ring cleavage

OT RM Module Enzyme Dihydroxylation Cleavage
Post-processing
1.14.12 Ferredoxin 1.18.1 1.3.1 1.13.11
OT RM004 M00545 map00360 1.14.12.19 3-phenylpropionate/trans-cinnamate dioxygenase K05708
hcaE
K05709
hcaF
K05710
hcaC
K00529
hcaD
K05711
hcaB
K05713
mhpB
K05714
mhpC
K02554
mhpD
K01666
mhpE
K04073
mhpF
OT RM004 M00539 map00622 1.14.12.25 p-cumate 2,3-dioxygenase K10619
cmtAb
K16303
cmtAc
K16304
cmtAd
K18227
cmtAa
K10620
cmtB
K10621
cmtC
K10622
cmtD
K10623
cmtE
OT RM005 M00551 map00362
map00622
1.14.12.10 benzoate/toluate 1,2-dioxygenase K05549
benA
xylX
K05550
benB
xylY
K05784
benC
xylZ
K05783
benD
xylL
K00446
dmpB
xylE
K10216
dmpD
xylF
K18364
bphH
xylJ
K18365
bphI
xylK
K18366
bphJ
xylQ
OT RG002 map00627 1.14.12.1 anthranilate 1,2-dioxygenase K05599
antA
K05600
antB
K11311
antC
OT RG002 map00627 1.14.12.1 anthranilate 1,2-dioxygenase K16319
andAc
K16320
andAd
K18248
andAb
K18249
andAa
OT RM004 M00547 map00362
map00623
1.14.12.3
1.14.12.11
benzene/toluene/chlorobenzene dioxygenase K03268
todC1
tcbAa
K16268
todC2
tcbAb
K18089
todB
tcbAc
K18090
todA
tcbAd
K16269
todD
tcbB
OT RM004 map00642 1.14.12.- ethylbenzene dioxygenase K14748
etbAa
K14749
etbAb
K14750
etbAc
K14751
etbC
K18092
etbD
OT RM014 M00534 map00626 1.14.12.12 naphthalene 1,2-dioxygenase K14579
nahAc
ndoB
K14580
nahAd
ndoC
K14578
nahAb
ndoA
K14581
nahAa
ndoR
K14582
nahB
doxE
K14583
nahC
K14584
nahD
K14585
nahE
K00152
nahF
1.14.13.172 salicylate 5-hydroxylase K18242
nagG
K18243
nagH
OT RM005 M00624 map00624 1.14.12.15 terephthalate 1,2-dioxygenase K18074
tphA2
K18075
tphA3
K18077
tphA1
K18076
tphB
K04100
ligA
K04101
ligB

K00448
pcaG
K00449
pcaH
OT RM004 M00623 map00624 1.14.12.7 phthalate 4,5-dioxygenase K18068
pht3
K18069
pht2
K18067
pht4
OT RM004 M00636 map00624 1.14.12.- phthalate 3,4-dioxygenase K18251
phtAa
K18252
phtAb
K18253
phtAc
K18254
phtAd
K18255
phtB
OT RM004 M00543 map00621 1.14.12.18 biphenyl 2,3-dioxygenase K08689
bphAa
K15750
bphAb
K18087
bphAc
K18088
bphAd
K08690
bphB
K00462
bphC
K10222
bphD
OT RG002 map00621 1.14.12.22 carbazole 1,9a-dioxygenase K15751
carAa
K15752
carAc
K15753
carAd
K15754
carBa
K15755
carBb
K15756
carC



Reaction modules

RM004 Dihydroxylation of aromatic ring, type 1 (dioxygenase and dehydrogenase reactions)
RM005 Dihydroxylation of aromatic ring, type 1a (dioxygenase and decarboxylating dehydrogenase reactions)
RG002 Dihydroxylation of aromatic ring, type 1b (single dioxygenase reaction)
1.14.12 1.3.1
RM004 C01407
benzene
RC00951
C04091 RC00386
C00090
catechol
RM005 C00180
benzoate
RC00270
C06321 RC00271
C00090
catechol
RG002 C00108
anthranilate
RC00192
C00090
catechol

RM009 Meta-cleavage of dihydroxylated aromatic ring
RM008 Ortho-cleavage of dihydroxylated aromatic ring
1.13.11
RM009 C00090
catechol
RC00387
C00682
RM008 C00090
catechol
RC00388
C02480


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Last updated: September 27, 2017