KEGG pathway map update history

[ Pathway maps | Drug maps | Brite files ]

DateMap noTitleStatus
2017-11-605226Gastric cancerNewly added
2017-9-2905225Hepatocellular carcinomaNewly added
2017-8-704926Relaxin signaling pathwayNewly added
2017-6-2700333Prodigiosin biosynthesesNewly added
2017-6-2605165Huma papillomavirus infectionNewly added
2017-6-2004218Cellular senescenceNewly added
2017-5-1505167Kaposi's sarcoma-associated herpesvirus infectionNewly added
2017-5-1104217NecroptosisNewly added
2017-3-2904216FerroptosisNewly added
2017-3-2804136Autophagy - otherNewly added
2017-3-2700405Phenazine biosynthesisNewly added
2017-3-904137Mitophagy - animalNewly added
2017-2-2204371Apelin signaling pathwayNewly added
2017-2-1305418Fluid shear stress and atherosclerosisNewly added
2017-2-1301059Biosynthesis of enediyne antibioticsNewly added
2017-2-704140Autophagy - animalNew version of 04140
2017-2-204138Autophagy - yeastNewly added; split from 04140
2017-1-1104657IL-17 signaling pathwayNewly added
2017-1-602026Biofilm formation - Escherichia coliNewly added
2016-12-1404659Th17 cell differentiationNewly added
2016-12-700515Mannose type O-glycan biosynthesisNewly added
2016-11-2802025Biofilm formation - Pseudomonas aeruginosaNewly added
2016-11-1404658Th1 and Th2 cell differentiationNewly added
2016-11-1005111Biofilm formation - Vibrio choleraeTitle changed in the new cateogry
2016-10-1101523Antifolate resistanceNewly added
2016-10-1104016MAPK signaling pathway - plantNewly added
2016-9-2300603Glycosphingolipid biosynthesis - globo and isoglobo seriesTitle changed
2016-9-1205224Breast cancerNewly added
2016-8-3104624Toll and Imd signaling pathwayNewly added
2016-8-900524Neomycin, kanamycin and gentamicin biosynthesisTitle changed
2016-8-501522Endocrine resistanceNewly added
2016-8-102024Quorum sensingNewly added
2016-7-1101524Platinum drug resistanceNewly added
2016-7-1100525Acarbose and validamycin biosynthesisNewly added
2016-6-2001521EGFR tyrosine kinase inhibitor resistanceNewly added in the new category
2016-6-104341Hedgehog signaling pathway - flyNewly added
2016-5-2704392Hippo signaling pathway - multiple speciesNewly added
2016-4-1804215Apoptosis - multiple speciesNewly added
2016-4-1400404Staurosporine biosynthesisNewly added
2016-3-3104214Apoptosis - flyNewly added
2016-2-304213Longevity regulating pathway - multiple speciesNewly added
2016-1-704212Longevity regulating pathway - wormNewly added
2015-12-1404211Longevity regulating pathwayNewly added
2015-12-1404139Mitophagy - yeastNewly added
2015-12-104933AGE-RAGE signaling pathway in diabetic complicationsNewly added
2015-10-2804072Phospholipase D signaling pathwayNewly added
2015-9-1404925Aldosterone synthesis and secretionNewly added
2015-8-2704931Insulin resistanceNewly added
2015-7-2404924Renin secretionNewly added
2015-7-1300220Arginine biosynthesisNewly added; split from 00330
2015-6-804923Regulation of lipolysis in adipocytesNewly added
2015-4-2701503Cationic antimicrobial peptide (CAMP) resistanceNewly added
2015-4-600261Monobactam biosynthesisNewly added
2015-3-2701130Biosynthesis of antibioticsNewly added global map
2015-3-904922Glucagon signaling pathwayNewly added
2015-2-1604071Sphingolipid signaling pathwayNewly added
2015-1-2001502Vancomycin resistanceNewly added
2014-12-2401501beta-Lactam resistanceNew map number; changed from 00312
2014-11-2805231Choline metabolism in cancerNewly added
2014-10-2705230Central carbon metabolism in cancerNewly added
2014-10-200332Carbapenem biosynthesisNewly added
2014-9-104550Signaling pathways regulating pluripotency of stem cellsNewly added
2014-7-2504024cAMP signaling pathwayNewly added
2014-7-1000403Indole diterpene alkaloid biosynthesisNewly added
2014-6-1204152AMPK signaling pathwayNewly added
2014-5-2604622cGMP-PKG signaling pathwayNewly added
2014-4-2804611Platelet activationNewly added
2014-4-404921Oxytocin signaling pathwayNewly added
2014-4-100312beta-Lactam resistanceNewly added in the new category
2014-2-2804750Inflammatory mediator regulation of TRP channelsNewly added
2014-1-2304919Thyroid hormone signaling pathwayNewly added
2013-12-2404068FoxO signaling pathwayNewly added
2013-11-1804261Adrenergic signaling in cardiomyocytesNewly added
2013-10-3004015Rap1 signaling pathwayNewly added
2013-10-2800254Aflatoxin biosynthesisNewly added
2013-10-2101212Fatty acid metabolismNewly added
2013-10-704014Ras signaling pathwayNewly added
2013-9-904932Non-alcoholic fatty liver disease (NAFLD)Newly added
2013-8-2800071Fatty acid degradationTitle changed
2013-8-905206MicroRNAs in cancerNewly added
2013-7-1205321Inflammatory bowel disease (IBD)Newly added
2013-7-204918Thyroid hormone synthesisNewly added
2013-6-2801200Carbon metabolismNewly added
2013-6-304917Prolactin signaling pathwayNewly added
2013-5-2404668TNF signaling pathwayNewly added
2013-5-204915Estrogen signaling pathwayNewly added
2013-4-2401230Biosynthesis of amino acidsNewly added
2013-4-2204913Ovarian steroidogenesisNewly added
2013-4-100365Furfural degradationNewly added
2013-4-105205Proteoglycans in cancerNewly added
2013-3-1504911Insulin secretionNewly added
2013-2-804390Hippo signaling pathwayNewly added
2013-1-904391Hippo signaling pathway - flyNewly added
2012-12-2701220Degradation of aromatic compoundsNewly added
2012-12-27012102-Oxocarboxylic acid metabolismNewly added
2012-11-704713Circadian entrainmentNewly added
2012-10-2404066HIF-1 signaling pathwayNewly added
2012-10-1605161Hepatitis BNewly added
2012-10-204151PI3K-Akt signaling pathwayNewly added
2012-9-1205204Chemical carcinogenesisNewly added
2012-8-305203Viral carcinogenesisNewly added
2012-6-1204064NF-kappa B signaling pathwayNewly added
2012-6-500984Steroid degradationNewly added
2012-4-2605034AlcoholismNewly added
2012-4-2305169Epstein-Barr virus infectionNewly added
2012-4-905033Nicotine addictionNewly added
2012-3-1505032Morphine addictionNewly added
2012-2-2105031Amphetamine addictionNewly added
2012-1-3005030Cocaine addictionNewly added
2012-1-2500909Sesquiterpenoid and triterpenoid biosynthesisTitle changed
2011-12-1604723Retrograde endocannabinoid signalingNewly added
2011-11-2404726Serotonergic synapseNewly added
2011-10-3005202Transcriptional misregulation in cancersNewly added
2011-9-505134LegionellosisNewly added
2011-9-204728Dopaminergic synapseNewly added
2011-8-1205168Herpes simplex infectionNewly added
2011-8-800073Cutin, suberine and wax biosynthesisNewly added
2011-8-800062Fatty acid elongationTitle changed
2011-8-103460Fanconi anemia pathwayNewly added
2011-8-104727GABAergic synapseNewly added
2011-7-2205132Salmonella infectionNewly added
2011-7-1305166HTLV-I infectionNewly added
2011-7-1104721Synaptic vesicle cycleNewly added
2011-6-1605133PertussisNewly added
2011-6-804725Cholinergic synapseNewly added
2011-5-3005164Influenza ANewly added
2011-5-1604724Glutamatergic synapseNewly added
2011-5-905152TuberculosisNewly added
2011-4-1804961Endocrine and other factor-regulated calcium reabsorptionNewly added
2011-4-1105162MeaslesNewly added
2011-3-3104978Mineral absorptionNewly added
2011-3-1100450Selenocompound metabolismTitle changed
2011-3-905323Rheumatoid arthritisNewly added
2011-3-704977Vitamin digestion and absorptionNewly added
2011-3-303008Ribosome biogenesis in eukaryotesNewly added
2011-2-2800720Carbon fixation pathways in prokaryotesTitle changed; newly drawn
2011-2-1404075Plant hormone signal transductionNewly added
2011-2-1400513Various types of N-glycan biosynthesisTitle changed
2011-2-905143African trypanosomiasisNewly added
2011-1-3104975Fat digestion and absorptionNewly added
2011-1-2400512Mucin type O-glycan biosynthesisTitle changed
2011-1-2400514Other types of O-glycan biosynthesisTitle changed
2011-1-1703015mRNA surveillance pathwayNewly added
2011-1-1304380Osteoclast differentiationNewly added
2011-1-1104976Bile secretionNewly added
2010-12-2801120Microbial metabolism in diverse environmentsNewly added global map
2010-12-603013RNA transportNewly added
2010-12-100361Chlorocyclohexane and chlorobenzene degradationTitle changed; newly drawn
2010-12-100362Benzoate degradationTitle changed; newly drawn
2010-12-100363Bisphenol degradationTitle changed; newly drawn
2010-12-100621Dioxin degradationTitle changed; newly drawn
2010-12-100622Xylene degradationTitle changed; newly drawn
2010-12-100623Toluene degradationTitle changed; newly drawn
2010-12-100624Polycyclic aromatic hydrocarbon degradationTitle changed; newly drawn
2010-12-100625Chloroalkane and chloroalkene degradationTitle changed; newly drawn
2010-12-100626Naphthalene degradationTitle changed; newly drawn
2010-12-100627Aminobenzoate degradationTitle changed; newly drawn
2010-12-100633Nitrotoluene degradationTitle changed; newly drawn
2010-12-100628Fluorene degradationDeleted; merged into 00621 and 00624
2010-12-100629Carbazole degradationDeleted; merged into 00621 and 00627
2010-12-1006311,2-Dichloroethane degradationDeleted; merged into 00625
2010-12-100632Benzoate degradation via CoA ligationDeleted; merged into 00362 and 00623
2010-12-1006413-Chloroacrylic acid degradationDeleted; merged into 00625
2010-11-1205160Hepatitis CNewly added
2010-11-904974Protein digestion and absorptionNewly added
2010-11-805150Staphylococcus aureus infectionNewly added
2010-11-104122Sulfur relay systemNewly added
2010-10-2504973Carbohydrate digestion and absorptionNewly added
2010-10-1205145ToxoplasmosisNewly added
2010-9-2104972Pancreatic secretionNewly added
2010-9-204141Protein processing in endoplasmic reticulumNewly added
2010-8-1605146AmoebiasisNewly added
2010-8-204971Gastric acid secretionNewly added
2010-7-2004145PhagosomeNewly added
2010-7-504970Salivary secretionNewly added
2010-6-2905144MalariaNewly added
2010-6-1404745Phototransduction - flyNewly added
2010-6-1405131ShigellosisNewly added
2010-5-3101110Biosynthesis of secondary metabolitesNewly added global map
2010-5-3104744PhototransductionNewly added
2010-5-3105100Bacterial invasion of epithelial cellsNewly added
2010-5-1805142Chagas diseaseNewly added
2010-5-1004966Collecting duct acid secretionNewly added
2010-4-1504112Cell cycle - CaulobacterNewly added
2010-4-1200524Butirosin and neomycin biosynthesisNewly added
2010-4-504964Proximal tubule bicarbonate reclamationNewly added
2010-3-3005140LeishmaniasisNewly added
2010-3-804962Vasopressin-regulated water reabsorptionNewly added
2010-3-800532Glycosaminoglycan biosynthesis - chondroitin sulfateTitle changed
2010-3-800534Glycosaminoglycan biosynthesis - heparan sulfateTitle changed
2010-3-800533Glycosaminoglycan biosynthesis - keratan sulfateTitle changed
2010-3-104626Plant-pathogen interactionNewly added
2010-2-404146PeroxisomeNewly added
2010-1-2800140Steroid hormone biosynthesisTitle changed; merging 00140 & 00150
2010-1-2800150Androgen and estrogen metabolismDeleted; merged into 00140
2010-1-2504960Aldosterone-regulated sodium reabsorptionNewly added
2010-1-600402Benzoxazinoid biosynthesisTitle changed
2009-12-2504672Intestinal immune network for IgA productionNewly added
2009-12-1004114Oocyte meiosisNewly added
2009-11-1904623Cytosolic DNA-sensing pathwayNewly added
2009-11-900440Phosphonate and phosphinate metabolismTitle changed
2009-11-905416Viral myocarditisNewly added
2009-11-203040SpliceosomeNewly added
2009-10-2704621NOD-like receptor signaling pathwayNewly added
2009-10-2604113Meiosis - yeastNewly added
2009-10-1305414Dilated cardiomyopathyNewly added
2009-9-1604622RIG-I-like receptor signaling pathwayNewly added
2009-9-1103018RNA degradationNewly added
2009-9-705412Arrhythmogenic right ventricular cardiomyopathy (ARVC)Newly added
2009-8-2500945Stilbenoid, diarylheptanoid and gingerol biosynthesisNewly added
2009-8-2500965Betalain biosynthesisNewly added
2009-8-2405410Hypertrophic cardiomyopathy (HCM)Newly added
2009-8-2404666Fc gamma R-mediated phagocytosisNewly added
2009-8-1800901Indole alkaloid biosynthesisTitle changed
2009-8-1800950Isoquinoline alkaloid biosynthesisTitle changed
2009-8-1800960Tropane, piperidine and pyridine alkaloid biosynthesisTitle changed
2009-8-1100121Secondary bile acid biosynthesisNewly added
2009-8-1100270Cysteine and methionine metabolismNew number; merging 00272 & 00271
2009-8-1100272Cysteine metabolismDeleted; merged into 00270
2009-8-1100271Methionine metabolismDeleted; merged into 00270
2009-8-700130Ubiquinone and other terpenoid-quinone biosynthesisTitle changed
2009-7-2704144EndocytosisNewly added
2009-7-2700100Steroid biosynthesisTitle changed
2009-7-2700900Terpenoid backbone biosynthesisTitle changed
2009-7-2700909Sesquiterpenoid biosynthesisNewly added
2009-7-1704722Neurotrophin signaling pathwayNewly added
2009-7-1705020Prion diseasesNewly added
2009-7-1400520Amino sugar and nucleotide sugar metabolismTitle changed
2009-7-1400530Aminosugars metabolismDeleted; merged into 00520
2009-7-1300250Alanine, aspartate and glutamate metabolismNew number; merging 00252 & 00251
2009-7-1300252Alanine and aspartate metabolismDeleted; merged into 00250
2009-7-1300251Glutamate metabolismDeleted; merged into 00250
2009-7-200120Primary bile acid biosynthesisTitle changed
2009-7-204142LysosomeNewly added
2009-7-100220Urea cycle and metabolism of amino groupsDeleted; merged into 00330
2009-6-1704062Chemokine signaling pathwayNewly added
2009-6-1503070Bacterial secretion systemTitle changed; category changed
2009-6-1503080Type IV secretion systemDeleted; merged into 03070
2009-6-1503090Type II secretion systemDeleted; merged into 03070
2009-6-804270Vascular smooth muscle contractionNewly added
2009-5-2600966Glucosinolate biosynthesisNewly added
2009-5-1304710Circadian rhythm - mammalTitle changed
2009-5-1304711Circadian rhythm - flySplit from 04710
2009-5-1304712Circadian rhythm - plantSplit from 04710
2009-5-800907Carotenoid biosynthesis, "Organism-specific"Deleted; represented by 00906
2009-4-2401100Metabolic pathwaysChanged to global map
2009-4-2202011ABC transporters, "Organism-specific"Deleted; represented by 02010
2009-4-2104260Cardiac muscle contractionNewly added
2009-4-200031Inositol metabolismDeleted; merged into 00562
2009-4-201030Glycan structures - biosynthesis 1Deleted; merged into 00510
2009-4-201031Glycan structures - biosynthesis 2Deleted; merged into 00510
2009-4-201032Glycan structures - degradationDeleted; merged into 00511
2009-4-100511Other glycan degradationTitle changed
2009-3-3101330Signaling molecules and interactionDeleted
2009-3-3101430Cell junctionsDeleted
2009-3-3101510Neurodegenerative diseasesDeleted
2009-3-2802021Two-component system, "Organism-specific"Deleted; represented by 02020
2009-3-2400130Ubiquinone and menaquinone biosynthesisTitle changed
2009-3-2305050Dentatorubropallidoluysian atrophy (DRPLA)Deleted; represented by H00060
2009-3-2305060Prion diseaseDeleted; represented by H00061
2009-3-2305016Huntington's diseaseNewly added
2009-3-2305040Huntington's diseaseDeleted
2009-2-1700602Glycosphingolipid biosynthesis - neo-lactoseriesDeleted; merged into 00601
2009-2-1700601Glycosphingolipid biosynthesis - lacto and neolacto seriesTitle changed
2009-2-1605010Alzheimer's diseaseNewly added
2009-2-1605010Alzheimer's diseaseDeleted
2008-12-2301060Biosynthesis of plant secondary metabolitesNewly added
2008-12-2301061Biosynthesis of phenylpropanoidsNewly added
2008-12-2301062Biosynthesis of terpenoids and steroidsNewly added
2008-12-2301063Biosynthesis of alkaloids derived from shikimate pathwayNewly added
2008-12-2301064Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acidNewly added
2008-12-2301065Biosynthesis of alkaloids derived from histidine and purineNewly added
2008-12-2301066Biosynthesis of alkaloids derived from terpenoid and polyketideNewly added
2008-12-2301070Biosynthesis of plant hormonesNewly added
2008-12-2205014Amyotrophic lateral sclerosis (ALS)Newly added
2008-12-2205030Amyotrophic lateral sclerosis (ALS)Deleted
2008-11-1005012Parkinson's diseaseNewly added
2008-11-1005020Parkinson's diseaseDeleted
2008-8-405322Systemic lupus erythematosusNewly added
2008-7-2903450Non-homologous end-joiningNewly added
2008-7-1405340Primary immunodeficiencyNewly added
2008-7-803440Homologous recombinationNewly added
2008-7-705110Vibrio cholerae infectionNewly added
2008-7-705111Vibrio cholerae pathogenic cycleNewly added
2008-7-705110Cholera - infectionDeleted
2008-7-705111Cholera - colonizationDeleted
2008-7-705112Cholera - diarrheaDeleted
2008-7-705113Cholera - environmentDeleted
2008-7-705114Cholera - life cycleDeleted
2008-7-400982Drug metabolism - cytochrome P450Newly added
2008-7-400983Drug metabolism - other enzymesNewly added
2008-6-2305332Graft-versus-host diseaseNewly added
2008-6-503430Mismatch repairNewly added
2008-6-205330Allograft rejectionNewly added
2008-5-2803420Nucleotide excision repairNewly added
2008-5-1403410Base excision repairNewly added
2008-4-2805320Autoimmune thyroid diseaseNewly added
2008-4-2200944Flavone and flavonol biosynthesisNewly added
2008-3-2605200Pathways in cancerNewly added
2008-3-805310AsthmaNewly added
2008-3-600908Zeatin biosynthesisNewly added
2008-2-2700981Insect hormone biosynthesisNewly added
2008-1-2500281Geraniol degradationNewly added
2008-1-2500364Fluorobenzoate degradationNewly added
2007-12-1000633Trinitrotoluene degradationNewly added
2007-10-1700232Caffeine metabolismNewly added
2007-10-1600942Anthocyanin biosynthesisNewly added
2007-10-1600592alpha-Linolenic acid metabolismNewly added
2007-10-101040Biosynthesis of unsaturated fatty acidsNewly added
2007-8-2105219Bladder cancerNewly added
2007-8-600943Isoflavonoid biosynthesisNewly added
2007-7-2600785Lipoic acid metabolismNewly added
2007-7-2404115p53 signaling pathwayNewly added
2007-7-305221Acute myeloid leukemiaNewly added
2007-5-2905215Prostate cancerNewly added
2007-5-2100906Carotenoid biosynthesisNewly added
2007-5-205222Small cell lung cancerNewly added
2007-5-205223Non-small cell lung cancerNewly added
2007-4-904614Renin/angiotensin systemNewly added
2007-4-405213Endometrial cancerNewly added
2007-4-404012ErbB signaling pathwayNewly added
2007-3-1500905Brassinosteroid biosynthesisNewly added
2007-3-500402Benzoxazinone biosynthesisNewly added
2007-2-2805211Renal cell carcinomaNewly added
2007-2-804916MelanogenesisNewly added
2007-1-2205218MelanomaNewly added
2007-1-2201058Acridone alkaloid biosynthesisNewly added
2006-12-2505217Basal cell carcinomaNewly added
2006-11-2205216Thyroid cancerNewly added
2006-10-2305220Chronic myeloid leukemiaNewly added
2006-9-2605214GliomaNewly added
2006-9-2100196Photosynthesis - antenna proteinsNewly added
2006-9-800565Ether lipid metabolismNewly added
2006-9-605212Pancreatic cancerNewly added
2006-8-2303320PPAR signaling pathwayNewly added
2006-8-905210Colorectal cancerNewly added
2006-7-504914Progesterone-mediated oocyte maturationNewly added
2006-6-1404912GnRH signaling pathwayNewly added
2006-5-3005130Pathogenic Escherichia coli infectionNewly added
2006-5-2404742Taste transductionNewly added
2006-4-2504140Regulation of autophagyNewly added
2006-4-1904740Olfactory transductionNewly added
2006-3-2804370VEGF signaling pathwayNewly added
2006-3-1604150mTOR signaling pathwayNewly added
2006-3-1000532Chondroitin sulfate biosynthesisNewly added
2006-3-1000534Heparan sulfate biosynthesisNewly added
2006-2-2805120Epithelial cell signaling in Helicobacter pylori infectionNewly added
2006-2-2704664Fc epsilon RI signaling pathwayNewly added
2006-2-904730Long-term depressionNewly added
2006-2-804612Antigen processing and presentationNewly added
2006-2-600980Metabolism of xenobiotics by cytochrome P450Newly added
2006-2-200590Arachidonic acid metabolismNewly added
2006-2-200591Linoleic acid metabolismNewly added
2006-1-3104720Long-term potentiationNewly added
2006-1-1104950Maturity onset diabetes of the youngNewly added

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