KEGG Pathway Maps

Map The KEGG PATHWAY database is a collection of manually drawn graphical diagrams, called KEGG pathway maps, representing molecular pathways for metabolism, genetic information processing, environmental information processing, other cellular processes, human diseases, and drug development. Each pathway is identified by a five-digit number preceded by one of: map, ko, ec, rn, and three- or four-letter organism code. The pathway map is drawn and updated with the notation shown below.
Notation
Color
coding
The pathway map without coloring is the original version that is manually drawn by in-house software named KegSketch. The other pathway maps with coloring are all computationally generated as follows.
  • Reference pathway: this is the original version; white boxes are hyperlinked to KO, ENZYME, and REACTION entries in metabolic pathways; they are hyperlinked to KO and GENES entries in non-metabolic pathways.
  • Reference pathway (KO): blue boxes are hyperlinked to KO entries that are selected from the original version.
  • Reference pathway (EC): blue boxes are hyperlinked to ENZYME entries that are selected from the original version.
  • Reference pathway (Reaction): blue boxes are hyperlinked to REACTION entries that are selected from the original version.
  • Organism-specific pathway: green boxes are hyperlinked to GENES entries by converting K numbers (KO identifiers) to gene identifiers in the reference pathway, indicating the presence of genes in the genome and also the completeness of the pathway.