KEGG image  Cardiovascular agents

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Antihypertensives

Class Name ATC KEGG Product (USA) Product (Japan)
Calcium channel blocker Dihydropyridine (DG01928) Amlodipine C08CA01 D00615 NORVASC AMLODIN, NORCASC
Felodipine C08CA02 D00319 PLENDIL SPLENDIL, MUNOBAL
Nicardipine C08CA04 D00617 CARDENE PERDIPINE
Nifedipine C08CA05 D00437 ADALAT CC, PROCARDIA ADARAT, EMABERIN, SEPAMIT
Nisoldipine C08CA07 D00618 SULAR BAYMYCARD
Nitrendipine C08CA08 D00629 BAYLOTENSIN
Manidipine C08CA11 D01553 CALSLOT
Barnidipine C08CA12 D01104 HYPOCA
Azelnidipine - D01145 CALBLOCK
Cilnidipine - D01173 ATELEC
Aranidipine - D01562 SAPRESTA, BEC
Efonidipine - D01604 LANDEL
Nilvadipine - D01908 NIVADIL
Benidipine C08CA15 D02045 CONIEL
Benzodiazepine Diltiazem C05AE03
C08DB01
D00616 CARDIZEM, DILACOR HERBESSER
Angiotensin II receptor antagonist
(DG01495)
Losartan C09CA01 D00357 COZAAR NU-LOTAN
Eprosartan C09CA02 D02082 TEVETEN
Valsartan C09CA03 D00400 DIOVAN DIOVAN
Irbesartan C09CA04 D00523 AVAPRO AVAPRO, IRBETAN
Candesartan cilexetil C09CA06 D00626 ATACAND CANDESARTAN, BLOPRESS
Telmisartan C09CA07 D00627 MICARDIS MICARDIS
Olmesartan medoxomil C09CA08 D01204 BENICAR OLMETEC
Azilsartan - D08864 AZILVA
Azilsartan kamedoxomil - D08865 EDARBI
ACE inhibitor
(DG01501)
Captopril C09AA01 D00251 CAPTOPRIL CAPTORIL
Enalapril C09AA02 D00621 VASOTEC RENIVACE
Lisinopril C09AA03 D00362 ZESTRIL ZESTRIL, LONGES
Perindopril C09AA04 D00624 ACEON COVERSYL
Ramipril C09AA05 D00421 ALTACE
Quinapril C09AA06 D00459 ACCUPRIL CONAN
Benazepril C09AA07 D00620 LOTENSIN CIBACEN
Cilazapril C09AA08 D01069 INHIBACE
Trandolapril C09AA10 D00383 MAVIK ODRIC, PRERAN
Delapril C09AA12 D01667 ADECUT
Moexipril C09AA13 D00623 UNIVASC
Temocapril C09AA14 D01119 ACECOL
Imidapril C09AA16 D01549 TANATRIL
Alacepril - D01900 CETAPRIL
Enalaprilat - D03769 ENALAPRILAT
Renin inhibitor (DG01923) Aliskiren C09XA02 D06412 TEKTURNA RASILEZ
Diuretics Thiazide (DG01749) Hydrochlorothiazide C03AA03 D00340 MICROZIDE HYDROCHLOROTHIAZIDE
Trichlormethiazide C03AA06 D00658 FLUITRAN
Benzylhydrochlorothiazide - D01246 BEHYD
Thiazide analogs Chlorthalidone C03BA04 D00272 THALITONE
Mefruside C03BA05 D01877 BAYCARON
Meticrane C03BA09 D01605 ARRESTEN
Indapamide C03BA11 D00345 INDAPAMIDE TENAXIL, NATRIX
Loop (DG01748) Furosemide C03CA01 D00331 FUROSEMIDE EUTENSIN, LASIX
Tripamide - D01895 NORMONAL
K-sparing (DG01885) Spironolactone C03DA01 D00443 ALDACTONE ALDACTONE
Eplerenone C03DA04 D01115 INSPRA SELARA
Triamterene C03DB02 D00386 DYRENIUM TRITEREN
beta-Adrenergic receptor antagonist non-selective (DG01464) Pindolol C07AA03 D00513 PINDOLOL CARVISKEN
Propranolol C07AA05 D00483 INNOPRAN XL, INDERAL INDERAL
Nadolol C07AA12 D00432 CORGARD NADIC
Carteolol C07AA15
S01ED05
D00599 CARTEOLOL HYDROCHLORIDE MIKELAN
Penbutolol C07AA23 D00602 LEVATOL
Carvedilol C07AG02 D03415 COREG, COREGCR
Nipradilol - D01691 NIPRANOL, HYPADIL
beta1-selective (DG01461) Metoprolol C07AB02 D00601 LOPRESSOR SELOKEN, LOPRESOR
Atenolol C07AB03 D00235 TENORMIN TENORMIN
Acebutolol C07AB04 D00597 SECTRAL ACETANOL
Betaxolol C07AB05
S01ED02
D00598 BETOPTIC S KERLONG
Bevantolol C07AB06 D01369 CALVAN
Bisoprolol C07AB07 D00634 ZEBETA MAINTATE
D02342 BISONO
Celiprolol C07AB08 D01741 SELECTOL
Nebivolol C07AB12 D06622 BYSTOLIC
alpha-Adrenergic receptor antagonist (DG01465) Prazosin C02CA01 D00609 MINIPRESS MINIPRESS
Doxazosin C02CA04 D00608 CARDURA CARDENALIN
Urapidil C02CA06 D01333 EBRANTIL
Terazosin G04CA03 D00610 TERAZOSIN HYTRACIN, VASOMET
Bunazosin - D01887 DETANTOL
alpha, beta-Adrenergic receptor antagonist Labetalol C07AG01 D00600 TRANDATE TRANDATE
Carvedilol C07AG02 D00255 COREG ARTIST
Amosulalol - D01469 LOWGAN
Arotinolol - D01830 AROTINOLOL HYDROCHLORIDE
Centrally acting sympatholytic agent (DG01738) Reserpine C02AA02 D00197 RESERPINE APOPLON
Methyldopa C02AB01 D00405 METHYLDOPA ALDOMET
Clonidine C02AC01
N02CX02
S01EA04
D00604 CATAPRES CATAPRES
Guanabenz - D00605 WYTENS
Vasodilators Hydralazine C02DB02 D01302 HYDRALAZINE APRESOLINE
Endothelin receptor antagonist (DG01502) Bosentan C02KX01 D01227 TRACLEER TRACLEER
Ambrisentan C02KX02 D07077 LETAIRIS VOLiBRIS
Prostaglandin I2 receptor agonist Epoprostenol B01AC09 D01337 VELETRI, FLOLAN FLOLAN
Beraprost B01AC19 D01551 CARELOAD, DORNER
Other Tocopherol A11HA03 D01530 JUVELA N
Deslanoside C01AA07 D01240 DIGILANOGEN
Nitroprusside C02DD01 D00614 NITROPRESS NITOPRO
Ergoloid mesylates C04AE01 D02268 HYDERGINE
Combination Calcium channel blocker - Angiotensin II receptor antagonist Amlodipine - Valsartan C09DB01 D09745 EXFORGE EXFORGE
Amlodipine - Olmesartan medoxomil C09DB02 D10285 AZOR
Amlodipine - Telmisartan C09DB04 D09743 TWYNSTA MICAMLO
Amlodipine - Irbesartan C09DB05 D10243 AIMIX
Amlodipine - Candesartan cilexetil C09DB07 D07569 UNISIA
Amlodipine - Valsartan - Hydrochlorothiazide C09DX01 D10286 EXFORGE HCT
Amlodipine - Olmesartan medoxomil - Hydrochlorothiazide C09DX03 D10288 TRIBENZOR
Azelnidipine - Olmesartan medoxomil - D09594 REZALTAS
Amlodipine - Azilsartan - D10524 ZACRAS
Cilnidipine - Alsartan - D10525 ATEDIO
Angiotensin II receptor antagonist - Diuretics Losartan - Hydrochlorothiazide C09DA01 D07895 HYZAAR PREMINENT
Eprosartan - Hydrochlorothiazide C09DA02 D10283 TEVETEN HCT
Valsartan - Hydrochlorothiazide C09DA03 D09197 DIOVAN HCT CO-DIO
Irbesartan - trichlormethiazide C09DA04 D10480 IRTRA
Candesartan cilexetil - Hydrochlorothiazide C09DA06 D09196 ATACAND HCT ECARD
Telmisartan - Hydrochlorothiazide C09DA07 D09219 MICARDIS HCT MICOMBI
Olmesartan medoxomil - Hydrochlorothiazide C09DA08 D10284 BENICAR HCT
Azilsartan medoxomil - Chlorthalidone C09DA09 D10589 EDARBYCLOR
ACE inhibitor - Diuretics Captopril - Hydrochlorothiazide C09BA01 D10276 CAPTOPRIL AND HYDROCHLOROTHIAZIDE
Enalapril maleate - Hydrochlorothiazide C09BA02 D10277 VASERETIC
Lisinopril - Hydrochlorothiazide C09BA03 D10268 ZESTORETIC
Benazepril - Hydrochlorothiazide C09BA07 D10279 LOTENSIN HCT
Fosinopril - Hydrochlorothiazide C09BA09 D10280 FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE
Moexipril - Hydrochlorothiazide C09BA13 D10281 UNIRETIC
ACE inhibitor - Antiarrhythmic Trandolapril - Verapamil C09BB10 D10282 TARKA
Renin inhibitor - Diuretics Aliskiren - Hydrochlorothiazide C09XA52 D10289 TEKTURNA HCT
Renin inhibitor - Calcium channel blocker Aliskiren - Amlodipine C09XA53 D10290 TEKAMLO
Renin inhibitor - Calcium channel blocker - Diuretics Aliskiren - Amlodipine - Hydrochlorothiazide C09XA54 D10291 AMTURNIDE
beta-Adrenergic receptor antagonist - Diuretics Propranolol - Hydrochlorothiazide C07BA05 D10274 PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
Nadolol - Bendroflumethiazide C07BA12 D10272 CORZIDE
Metoprolol - Hydrochlorothiazide C07BB02 D10273 DUTOPROL
Bisoprolol - Hydrochlorothiazide C07BB07 D10275 ZIAC
Atenolol - Chlorthalidone C07CB03 D10592 TENORETIC
Centrally acting sympatholytic agent - Diuretics Benzylhydrochlorothiazide - Reserpine - Carbazochrome C02AA52
C02LA51
D04266 BEHYD-RA
Diuretics Hydrochlorothiazide - Spironolactone C03EA01 D10270 ALDACTAZIDE

Antiarrhythmics

Class Name ATC KEGG Product (USA) Product (Japan)
Sicilian Gambit Vaughan Wiliams
Ion channel Na Fast Class Ib Lidocaine C01BB01 D02086 XYLOCAINE OLIVES
Class Ib Mexiletine C01BB02 D00639 MEXILETINE HYDROCHLORIDE MEXITIL
Class III Amiodarone C01BD01 D00636 NEXTERONE ANCARON
Class II Propranolol C07AA05 D00483 INNOPRAN XL INDERAL
Class IV Verapamil C08DA01 D00619 VERELAN PM VASOLAN
- Bepridil C08EA02 D00631 BEPRICOR
Med Class Ia Quinidine C01BA01 D00642 QUINIDINE GLUCONATE
D02272 QUINIDINE SULFATE QUINIDINE SULFATE
Class Ia Procainamide C01BA02 D00477 AMISALIN PROCAINAMIDE HYDROCHLORIDE
Class Ib Aprindine C01BB04 D01326 ASPENON
Class Ic Propafenone C01BC03 D00640 RYTHMOL PRONON
Slow Class Ia Disopyramide C01BA03 D00303 RYTHMODAN
D00637 NORPACE RYTHMODAN
Class Ia Cibenzoline C01BG07 D01455 CIVENOL
Class Ia Pirmenol - D01785 PIMENOL
Class Ic Flecainide C01BC04 D00638 FLECAINIDE ACETATE TAMBOCOR
Class Ic Pilsicainide - D01554 SUNRYTHM
Ca2+ Class Ib Aprindine C01BB04 D01326 ASPENON
Class Ia Cibenzoline C01BG07 D01455 CIVENOL
- Bepridil C08EA02 D00631 BEPRICOR
Class IV Verapamil C08DA01 D00619 VERELAN PM VASOLAN
Class IV Diltiazem C05AE03
C08DB01
D00616 DILACOR HERBESSER
Class III Amiodarone C01BD01 D00636 NEXTERONE ANCARON
K Class Ia Procainamide C01BA02 D00477 AMISALIN PROCAINAMIDE HYDROCHLORIDE
Class Ia Disopyramide C01BA03 D00303 RYTHMODAN
D00637 NORPACE RYTHMODAN
Class Ia Quinidine C01BA01 D00642 QUINIDINE GLUCONATE
D02272 QUINIDINE SULFATE QUINIDINE SULFATE
Class Ib Aprindine C01BB04 D01326 ASPENON
Class Ia Cibenzoline C01BG07 D01455 CIVENOL
Class Ia Pirmenol - D01785 PIMENOL
Class Ic Flecainide C01BC04 D00638 FLECAINIDE ACETATE TAMBOCOR
- Bepridil C08EA02 D00631 BEPRICOR
Class II
Class III
Sotalol C07AA07 D01026 SOTYLIZE SOTACOR
Class III Amiodarone C01BD01 D00636 NEXTERONE ANCARON
Class III Nifekalant - D01856 SHINBIT
If Class Ib Aprindine C01BB04 D01326 ASPENON
Receptor α Class Ia Quinidine C01BA01 D00642 QUINIDINE GLUCONATE
D02272 QUINIDINE SULFATE QUINIDINE SULFATE
Class IV Verapamil C08DA01 D00619 VERELAN PM VASOLAN
Class III Amiodarone C01BD01 D00636 NEXTERONE ANCARON
β Class Ic Propafenone C01BC03 D00640 RYTHMOL PRONON
Class II
Class III
Sotalol C07AA07 D01026 SOTYLIZE SOTACOR
Class III Amiodarone C01BD01 D00636 NEXTERONE ANCARON
Class II Propranolol C07AA05 D00483 INNOPRAN XL INDERAL
M2 Class Ia Disopyramide C01BA03 D00303 RYTHMODAN
D00637 NORPACE RYTHMODAN
Class Ia Quinidine C01BA01 D00642 QUINIDINE GLUCONATE
D02272 QUINIDINE SULFATE QUINIDINE SULFATE
Class Ia Cibenzoline C01BG07 D01455 CIVENOL
Class Ia Pirmenol - D01785 PIMENOL
- Atropine A03BA01
S01FA01
D02069 ATROPINE SULFATE ATROPINE SULFATE
- Digoxin C01AA05 D00298 LANOXIN DIGOSIN
A1 - Adenosine C01EB10 D02300 ADENOSINE ATP, ADETPHOS
Pump Na+, K+-, ATPase - Digoxin C01AA05 D00298 LANOXIN DIGOSIN
Other Class III Dofetilide C01BD04 D00647 TIKOSYN
Class II Alprenolol C07AA01 D01182 SKAJILOL
Class II Nadolol C07AA12 D00432 CORGARD NADIC
Class II Metoprolol C07AB02 D00601 LOPRESSOR SELOKEN, LOPRESOR
Class II Atenolol C07AB03 D00235 TENORMIN TENORMIN
Class II Acebutolol C07AB04 D00597 SECTRAL ACETANOL
Class II Esmolol C07AB09 D00644 BREVIBLOC BREVIBLOC
- Magnesium sulfate A06AD04
A12CC02
B05XA05
D11AX05
V04CC02
D01108 MAGNESIUM SULFATE MAGNESIUM SULFATE
Class III Ibutilide C01BD05 D00648 CORVERT
Class II Carteolol C07AA15
S01ED05
D00599 CARTEOLOL HYDROCHLORIDE MIKELAN


Related KEGG pathway maps
Category Title
Normal pathway map Cardiac muscle contraction
Vascular smooth muscle contraction
Renin-angiotensin system
Adrenergic signaling in cardiomyocytes
Disease pathway map Hypertrophic cardiomyopathy
Dilated cardiomyopathy
Drug structure map Antiarrhythmic drugs


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Last updated: April 4, 2017