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Rx-to-OTC Switch List in the U.S.A.

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Approved C/D number Ingredient Category
1976D00663Brompheniramine maleateantihistamine
D00665Chlorpheniramine maleateantihistamine
Oxmetazoline hydrochloridenasal decongestant
D00485Pseudoephedrine hydrochloridenasal decongestant
D05649Pseudoephedrine sulfatenasal decongestant
D00757Xylometazoline hydrochloridenasal decongestant
1978D02327Doxylamine succinate (NDA)sleep-aid
1979D00088Hydrocortisoneantipruritic (anti-itch)
D00165Hydrocortisone acetateantipruritic (anti-itch)
1980Acidulated phosphate fluoride rinsedental rinse
D00943Sodium fluoride rinsedental rinse
D05919Stannous fluoride gelanticaries gel
D05919Stannous fluoride rinsedental rinse
D04018Ephedrine sulfateanorectal/vasoconstrictor
D01386Epinephrine hydrochlorideanorectal/vasoconstrictor
D00511Phenylephrine hydrochlorideanorectal/vasoconstrictor
1981D00665Chlorpheniramine maleate (NDA)antihistamine
D01224Phenylpropanolamine hydrochloride (NDA)nasal decongestant
D00669Diphenhydramine hydrochloride (NDA)antitussive
1982D00339Haloproginantifungal
D00882Miconazole nitrateantifungal
D00669Diphenhydramine hydrochloridesleep-aid
D03854Diphenhydramine monocitratesleep-aid
D00735Dyclonine hydrochlorideoral anesthetic
D03704Dexbrompheniramine maleate (NDA)antihistamine
D05649Pseudoephedrine sulfate (NDA)nasal decongestant
D01782Triprolidine hydrochlorideantihistamine
1984D00126Ibuprofen (NDA)internal analgesic/antipyretic
1985D03704Dexbrompheniramine maleateantihistamine
D00669Diphenhydramine hydrochlorideantihistamine
D00485Pseudoephedrine hydrochloride(NDA)nasal decongestant
D01782Triprolidine hydrochloride (NDA)antihistamine
1986D01022Oxymetazoline hydrochloride (NDA)occular vasoconstrictor
D00486Pyrantel pamoateanthelmintic
1987D00863Povidone iodine sponge (NDA)antimicrobial
D00669Diphenhydramine hydrochlorideantiemetic
D03704Dexbrompheniramine maleate (NDA)antihistamine
D01389Chlophedianol hydrochlorideantitussive
D02327Doxylamine succinateantihistamine
1988C07080Loperamide (NDA)antidiarrheal
1989D09004,D04682Hydrogenated soybean oil and lecithincholecystokinetic
D00126,D00485Ibuprofen, Pseudoephedrine hydrochloride (NDA)analgesic/decongestant
D00282Clotrimazole (NDA)antifungal
1990D05443Permethrin (NDA)pediculicide (head lice)
D00282Clotrimazole (NDA)anticandidal
D00882Miconazole nitrateanticandidal
1991D00088Hydrocortisoneantipruritic (anti-itch)
D00165Hydrocortisone acetateantipruritic (anti-itch)
1992D00666Clemastine fumarate (NDA)antihistamine
D00666 D01224Clemastine fumarate in combination with phenylpropanolamine hydrochloride (NDA)antihistamine/decongestant
D00668Dexchlorpheniramine maleateantihistamine
1994D00970Naproxen sodium (NDA)internal analgesic/antipyretic
D02133 D00743Pheniramine maleate with naphazoline hydrochloride (NDA)ophthalmic antihistamine/decongestant
D02950 D00743Antazoline phosphate with naphazoline hydrochloride (NDA)ophthalmic antihistamine/decongestant
1995D00318Famotidine (NDA)acid reducer
Ibuprofen suspension 100mg/5ml for pediatric use (NDA)internal analgesic/antipyretic
D00295Cimetidine (NDA)acid reducer
D00132Ketoprofen (NDA)internal analgesic
D00422Ranitidine (NDA)acid reducer
D00880Butoconazole nitrate (NDA)anticandidal
1996D00418Minoxidil (NDA)hair grower
D05157Nicotine polacrilex (NDA)smoking cessation
D00440Nizatidine (NDA)acid reducer
D00882Miconazole nitrate (NDA)anticandidal
D03365Nicotine transdermal system (NDA)smoking cessation
D00282Clotrimazole (NDA)anticandidal
D03365Nicotine transdermal system (NDA)smoking cessation
D03085Bentoquatam (NDA)poison ivy protection
1997D00526Cromolyn sodium (NDA)allergy prevention & treatment
D00890Tioconazole (NDA)anticandidal
C07080,D05841Loperamide, Simethicone (NDA)antidiarrheal/antigas
D06226Triclosan (dentifrice) (NDA)antigingivitis
D00351Ketoconazole (NDA)dandruff shampoo
D00418Minoxidil (NDA)hair grower
1998D00109,C07481,
D00217		Aspirin, Caffeine, Acetaminophen (NDA)migraine
D00882Miconazole nitrate (NDA)anticandidal
1999D02219Terbinafine hydrochloride (NDA)antifungal
D00295Cimetidine suspension (NDA)acid reducer
D00970,D00485Naproxen sodium, Pseudoephedrine hydrochloride (NDA)analgesic/decongestant
2000D00126Ibuprofen (NDA)migraine
D00126Ibuprofen (NDA)migraine
D03884Docosanol (NDA)cold sore/fever blister
D00318,D00932,
D00731		Famotidine, Calcium carbonate, Magnesium hydroxide (NDA)heartburn, acid indigestion
2001D01093Butenafine hydrochloride (NDA)athlete's foot, jock itch, ringworm
2002D00126,D00485Ibuprofen, Pseudoephedrine hydrochloride, suspension for pediatric use (NDA)analgesic/decongestant
D00337Guaifenesin extended-release tablet (NDA)expectorant
D05157Nicotine polacrilex troche/lozenge (NDA)smoking cessation
D00364Loratadine (NDA)antihistamine
D00364,D05649Loratadine, Pseudoephededrine sulfate (NDA)antihistamine/decongestant
2003D05259Omeprazole magnesiumacid reducer to treat frequent heartburn
D00364Loratadine (NDA)hives relief
2005D03854,D00126
D00669,		Diphenhydramine citrate & Ibuprofen (NDA)
Diphenhydramine hydrochloride & Ibuprofen potassium (NDA)		analgesic sleep-aid
2006D03932Ecamsule (combined with avobenzone and octocrylene (NDA)sunscreen
D00950Levonorgestrel (NDA)contraceptive
D03370Polyethylene glycol 3350 (NDA)laxative
D08105Ketotifen (NDA)antihistamine eye
2007D04028Orlistat (NDA)weight loss aid
D00664,D00485Cetirizine HCl & Pseudoephedrine HCl (NDA)antihistamine/decongestant
D00664Cetirizine HCl (NDA)antihistamine, hives relief
2009D00355Lansoprazole (NDA)acid reducer to treat frequent heartburn
D00950Levonorgestrel (NDA)contraceptive
D00455,D01203Omeprazole and sodium bicarbonate (NDA)acid reducer to treat frequent heartburn
2010D00126,D00511Ibuprofen and phenylephrine HCl (NDA)analgesic/decongestant
2011D00671Fexofenadine hydrochloride (NDA)antihistamine
D00671,D00485Fexofenadine hydrochloride and pseudoephedrine HCl (NDA)antihistamine/decongestant

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Last updated: April 27, 2011
According to the Consumer Healthcare Products Association