Dictionary of Protein Sites and Patterns
Release 2022_02, May 22
Swiss Institute of Bioinformatics
2,652 entries

Protein families database of alignments and HMMs
Release 35.0, Nov 21
The Pfam Consortium
19,482 entries

NCBI Conserved Domain Database
Release 3.20, Sep 22
National Center for Biotechnology Information
59,693 entries