Dictionary of Protein Sites and Patterns
Release 2022_02, May 22
Swiss Institute of Bioinformatics
2,652 entries

Protein families database of alignments and HMMs
Release 37.2, Feb 25
The Pfam Consortium
23,941 entries

NCBI Conserved Domain Database
Release 3.21, May 24
National Center for Biotechnology Information
62,455 entries