polyphosphate polyphosphohydrolase; Polyphosphate + n H2O <=> (n+1) Oligophosphate

reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + 16 H2O + 8 Reduced ferredoxin <=> 8 e- + 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin

diphosphate phosphohydrolase; pyrophosphate phosphohydrolase; Diphosphate + H2O <=> 2 Orthophosphate

GTP:GTP guanylyltransferase; 2 GTP <=> Diphosphate + P1,P4-Bis(5'-guanosyl) tetraphosphate

pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating); Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2

3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming); D-Ribulose 1,5-bisphosphate + CO2 + H2O <=> 2 3-Phospho-D-glycerate

[phosphorylase a] phosphohydrolase; [glycogen phosphorylase] phosphohydrolase; Phosphorylase a + 4 H2O <=> 2 Phosphorylase b + 4 Orthophosphate

ATP diphosphohydrolase (phosphate-forming); ATP + 2 H2O <=> AMP + 2 Orthophosphate

ATP phosphohydrolase; ATP + H2O <=> ADP + Orthophosphate

ATP diphosphohydrolase (diphosphate-forming); ATP pyrophosphohydrolase; ATP + H2O <=> AMP + Diphosphate

ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming); ATP <=> 3',5'-Cyclic AMP + Diphosphate

NADP+ 2'-phosphohydrolase; NADP+ + H2O <=> Orthophosphate + NAD+

NADP+:nicotinate ADP-ribosyltransferase; NADP+ + Nicotinate <=> Nicotinamide + Nicotinic acid adenine dinucleotide phosphate

ADP phosphohydrolase; ADP + H2O <=> AMP + Orthophosphate

P1,P4-bis(5'-adenosyl)-tetraphosphate nucleotidebisphosphohydrolase; P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> 2 ADP

ADP:ATP adenylyltransferase; ADP + ATP <=> Orthophosphate + P1,P4-Bis(5'-adenosyl)tetraphosphate

adenosine-tetraphosphate phosphohydrolase; Adenosine tetraphosphate + H2O <=> ATP + Orthophosphate

(6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide hydro-lyase (ATP-hydrolysing, NADH-forming); ATP + (6S)-6beta-Hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide <=> ADP + Orthophosphate + NADH

ATP:nicotinamide-nucleotide adenylyltransferase; ATP + Nicotinamide D-ribonucleotide <=> Diphosphate + NAD+

triphosphate phosphohydrolase; Triphosphate + H2O <=> Diphosphate + Orthophosphate

ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase; 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP

ATP:5-hydroxymethyldeoxycytidylate phosphotransferase; 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ADP <=> 5-Hydroxymethyldeoxycytidylate + ATP

carbon-dioxide:ammonia ligase (ADP-forming,carbamate-phosphorylating); 2 ATP + Ammonia + CO2 + H2O <=> 2 ADP + Orthophosphate + Carbamoyl phosphate

ATP:carbamate phosphotransferase; ATP + Ammonia + HCO3- <=> ADP + Carbamoyl phosphate + H2O

UDP phosphohydrolase; UDP + H2O <=> UMP + Orthophosphate

uridine triphosphate:AMP phosphotransferase; UTP:AMP phosphotransferase; UTP + AMP <=> UDP + ADP

UTP phosphohydrolase; UTP + H2O <=> UDP + Orthophosphate

ATP:FMN adenylyltransferase; ATP + FMN <=> Diphosphate + FAD

phosphoprotein phosphohydrolase; Phosphoprotein + H2O <=> Protein + Orthophosphate

pyridoxal-5'-phosphate phosphohydrolase; Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate

ATP:pyridoxal 5'-phosphotransferase; ATP + Pyridoxal <=> ADP + Pyridoxal phosphate

ATP:L-methionine S-adenosyltransferase; Orthophosphate + Diphosphate + S-Adenosyl-L-methionine <=> ATP + L-Methionine + H2O

AMP phosphoribohydrolase; AMP + H2O <=> Adenine + D-Ribose 5-phosphate

adenosine 5'-monophosphate phosphohydrolase; AMP + H2O <=> Adenosine + Orthophosphate

P1,P4-bis(5'-adenosyl)-tetraphosphate adenylohydrolase; P1,P4-Bis(5'-adenosyl)tetraphosphate + H2O <=> ATP + AMP

P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase; P1,P3-Bis(5'-adenosyl) triphosphate + H2O <=> ADP + AMP

adenosine-3',5'-bisphosphate 3'-phosphohydrolase; Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate

deamido-NAD+:ammonia ligase (AMP-forming); ATP + Deamino-NAD+ + Ammonia <=> AMP + Diphosphate + NAD+

AMP:diphosphate phospho-D-ribosyltransferase; AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate

adenosine 3',5'-phosphate 5'-nucleotidohydrolase; 3',5'-Cyclic AMP + H2O <=> AMP

ATP:pyruvate,water phosphotransferase; ATP + Pyruvate + H2O <=> AMP + Phosphoenolpyruvate + Orthophosphate

ATP:pyruvate,phosphate phosphotransferase; ATP + Pyruvate + Orthophosphate <=> AMP + Phosphoenolpyruvate + Diphosphate

pyruvate:oxygen 2-oxidoreductase (phosphorylating); Pyruvate + Orthophosphate + Oxygen <=> Acetyl phosphate + Hydrogen peroxide + CO2

phosphoenolpyruvate phosphohydrolase; Phosphoenolpyruvate + H2O <=> Pyruvate + Orthophosphate

acetate:CoA ligase (ADP-forming); ATP + Acetate + CoA <=> ADP + Acetyl-CoA + Orthophosphate

acetyl-CoA:phosphate acetyltransferase; Acetyl-CoA + Orthophosphate <=> CoA + Acetyl phosphate

acetate:CoA ligase (AMP-forming); ATP + Acetate + CoA <=> AMP + Diphosphate + Acetyl-CoA

ATP:L-glutamate 5-phosphotransferase; ATP + L-Glutamate <=> ADP + L-Glutamyl 5-phosphate

5-oxo-L-proline amidohydrolase (ATP-hydrolysing); ATP + 5-Oxoproline + 2 H2O <=> ADP + Orthophosphate + L-Glutamate

L-glutamate:ammonia ligase (ADP-forming); ATP + L-Glutamate + Ammonia <=> ADP + Orthophosphate + L-Glutamine

deamido-NAD+:L-glutamine amido-ligase (AMP-forming); ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate

pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating); Pyridoxamine phosphate + H2O + Oxygen <=> Pyridoxal phosphate + Ammonia + Hydrogen peroxide

pyridoxine 5'-phosphate:oxygen oxidoreductase; Pyridoxine phosphate + Oxygen <=> Hydrogen peroxide + Pyridoxal phosphate

ammonium:acceptor oxidoreductase (ATP-forming); Acceptor + Ammonia + H2O + 2 Orthophosphate + 2 ADP <=> Hydroxylamine + Reduced acceptor + 2 ATP + 2 H2O

UDP-glucose glucophosphohydrolase; UDP-glucose + H2O <=> UMP + D-Glucose 1-phosphate

UTP:alpha-D-glucose-1-phosphate uridylyltransferase; UTP + D-Glucose 1-phosphate <=> Diphosphate + UDP-glucose

ATP:D-glucose 6-phosphotransferase; ATP + D-Glucose <=> ADP + D-Glucose 6-phosphate

D-glucose-6-phosphate phosphohydrolase; D-Glucose 6-phosphate + H2O <=> D-Glucose + Orthophosphate

D-glucose-1-phosphate phosphohydrolase; D-Glucose 1-phosphate + H2O <=> D-Glucose + Orthophosphate

ATP:acetate phosphotransferase; ATP + Acetate <=> ADP + Acetyl phosphate

ATP:acetate adenylyltransferase; ATP + Acetate <=> Diphosphate + Acetyl adenylate

acetyl phosphate phosphohydrolase; Acetyl phosphate + H2O <=> Acetate + Orthophosphate

phosphonoacetate phosphonohydrolase; Phosphonoacetate + H2O <=> Acetate + Orthophosphate

diphosphate:acetate phosphotransferase; Diphosphate + Acetate <=> Orthophosphate + Acetyl phosphate

GDP phosphohydrolase; GDP + H2O <=> GMP + Orthophosphate

nucleoside-diphosphate phosphohydrolase; NDP + H2O <=> Nucleotide + Orthophosphate

ATP:nucleoside-diphosphate phosphotransferase; ATP + NDP <=> ADP + Nucleoside triphosphate

nucleoside-triphosphate:AMP phosphotransferase; Nucleoside triphosphate + AMP <=> NDP + ADP

ATP:nucleoside-phosphate phosphotransferase; ATP + Nucleoside phosphate <=> ADP + NDP

GTP phosphohydrolase; GTP + H2O <=> GDP + Orthophosphate

guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase; Guanosine 3',5'-bis(diphosphate) + H2O <=> GDP + Diphosphate

pyruvate:carbon-dioxide ligase (ADP-forming); ATP + Pyruvate + HCO3- <=> ADP + Orthophosphate + Oxaloacetate

phosphate:oxaloacetate carboxy-lyase (adding phosphate;phosphoenolpyruvate-forming); Orthophosphate + Oxaloacetate <=> H2O + Phosphoenolpyruvate + CO2

diphosphate:oxaloacetate carboxy-lyase (transphosphorylating;phosphoenolpyruvate-forming); pyrophosphate:oxaloacetate carboxy-lyase (transphosphorylating); Diphosphate + Oxaloacetate <=> Orthophosphate + Phosphoenolpyruvate + CO2

acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]; ATP + Citrate + CoA <=> ADP + Orthophosphate + Acetyl-CoA + Oxaloacetate

deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dATP + DNA <=> Diphosphate + DNA

deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dGTP + DNA <=> Diphosphate + DNA

deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dCTP + DNA <=> Diphosphate + DNA

deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed); dTTP + DNA <=> Diphosphate + DNA

deoxynucleoside triphosphate:DNA deoxynucleotidyltransferase; Deoxynucleoside triphosphate + DNA(n) <=> Diphosphate + DNA(n+1)

(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming); ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)

medium-chain-fatty-acid:CoA ligase (AMP-forming); ATP + Medium-chain fatty acid + CoA <=> AMP + Diphosphate + Medium-chain acyl-CoA

long-chain-fatty-acid:CoA ligase (AMP-forming); ATP + Long-chain fatty acid + CoA <=> AMP + Diphosphate + Long-chain acyl-CoA

carboxylic acid:CoA ligase (GDP-forming); GTP + Carboxylate + CoA <=> GDP + Orthophosphate + Acyl-CoA

succinate:CoA ligase (ADP-forming); ATP + Succinate + CoA <=> ADP + Orthophosphate + Succinyl-CoA

UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase; UTP + N-Acetyl-alpha-D-glucosamine 1-phosphate <=> Diphosphate + UDP-N-acetyl-alpha-D-glucosamine

GTP 7,8-8,9-dihydrolase; GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate

GTP 7,8-8,9-dihydrolase (diphosphate-forming); GTP + 4 H2O <=> Formate + 2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 Orthophosphate

GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase; GTP + H2O <=> GMP + Diphosphate

GTP 8,9-hydrolase; GTP + H2O <=> Formamidopyrimidine nucleoside triphosphate

ATP:GTP 3'-diphosphotransferase; ATP + GTP <=> AMP + Guanosine 3'-diphosphate 5'-triphosphate

succinate:CoA ligase (GDP-forming); GTP + Succinate + CoA <=> GDP + Orthophosphate + Succinyl-CoA

GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming); GTP <=> 3',5'-Cyclic GMP + Diphosphate

ATP:polynucleotide adenylyltransferase; ATP:RNA adenylyltransferase; ATP + RNA <=> Diphosphate + RNA

polyribonucleotide ligase (cyclizing, AMP-forming); ATP + RNA <=> AMP + Diphosphate + RNA(circular)

polyribonucleotide:phosphate adenylyltransferase; RNA + Orthophosphate <=> RNA + ADP

polyribonucleotide:phosphate uridylyltransferase; RNA + Orthophosphate <=> RNA + UDP

polyribonucleotide:phosphate guanylyltransferase; RNA + Orthophosphate <=> RNA + GDP

polyribonucleotide:phosphate cytidylyltransferase; RNA + Orthophosphate <=> RNA + CDP

GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA guanylyltransferase (RNA-directed); GTP + RNA <=> Diphosphate + RNA

CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA cytidylyltransferase (RNA-directed); CTP + RNA <=> Diphosphate + RNA

UTP:RNA uridylyltransferase; UTP + RNA <=> Diphosphate + RNA

nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed); nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed); Nucleoside triphosphate + RNA <=> Diphosphate + RNA

L-aspartate:ammonia ligase (ADP-forming); ATP + L-Aspartate + Ammonia <=> ADP + Orthophosphate + L-Asparagine

L-aspartate:ammonia ligase (AMP-forming); ATP + L-Aspartate + Ammonia <=> AMP + Diphosphate + L-Asparagine

gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming); ATP + gamma-L-Glutamyl-L-cysteine + Glycine <=> ADP + Orthophosphate + Glutathione

UTP:alpha-D-galactose-1-phosphate uridylyltransferase; UTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + UDP-alpha-D-galactose

3'-phosphoadenylyl-sulfate sulfohydrolase; 3'-phosphoadenylyl-sulfate nucleotidohydrolase; 3'-Phosphoadenylyl sulfate + H2O <=> Sulfate + Adenosine 3',5'-bisphosphate

3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase; 3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate

cytidine-5'-monophosphate phosphoribohydrolase; CMP + H2O <=> Cytosine + D-Ribose 5-phosphate

cytidine-5'-monophosphate phosphohydrolase; CMP + H2O <=> Cytidine + Orthophosphate

CDP phosphohydrolase; CDP + H2O <=> CMP + Orthophosphate

CTP diphosphohydrolase (diphosphate-forming); CTP pyrophosphohydrolase; CTP + H2O <=> CMP + Diphosphate

ATP:formate phosphotransferase; ATP + Formate <=> ADP + Formyl phosphate

ATP:sulfate adenylyltransferase; ATP + Sulfate <=> Diphosphate + Adenylyl sulfate

ADP:sulfate adenylyltransferase; ADP + Sulfate <=> Orthophosphate + Adenylyl sulfate

3'-phosphoadenylylsulfate:17beta-estradiol 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Estradiol-17beta <=> Adenosine 3',5'-bisphosphate + Estradiol-17beta 3-sulfate

3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + 2-Methoxyestrone <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestrone 3-sulfate

3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + 2-Methoxy-17beta-estradiol <=> Adenosine 3',5'-bisphosphate + 2-Methoxyestradiol-17beta 3-sulfate

acyl phosphate phosphohydrolase; Acyl phosphate + H2O <=> Carboxylate + Orthophosphate

riboflavin-5-phosphate phosphohydrolase; FMN + H2O <=> Riboflavin + Orthophosphate

D-glucose-1-phosphate:riboflavin 5'-phosphotransferase; D-Glucose 1-phosphate + Riboflavin <=> D-Glucose + FMN

ATP:L-arginine Nomega-phosphotransferase; ATP + L-Arginine <=> ADP + L-Arginine phosphate

CTP phosphohydrolase; CTP + H2O <=> CDP + Orthophosphate

UTP:ammonia ligase (ADP-forming); ATP + UTP + Ammonia <=> ADP + Orthophosphate + CTP

UTP:L-glutamine amido-ligase (ADP-forming); ATP + UTP + L-Glutamine + H2O <=> ADP + Orthophosphate + CTP + L-Glutamate

CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming); CTP <=> 3',5'-Cyclic CMP + Diphosphate

HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating); 2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate

L-aspartate:L-glutamine amido-ligase (AMP-forming); ATP + L-Aspartate + L-Glutamine + H2O <=> AMP + Diphosphate + L-Asparagine + L-Glutamate

O-phospho-L-serine phosphohydrolase; O-Phospho-L-serine + H2O <=> L-Serine + Orthophosphate

diphosphate:L-serine O-phosphotransferase; Diphosphate + L-Serine <=> Orthophosphate + O-Phospho-L-serine

thiamin diphosphate phosphohydrolase; Thiamin diphosphate + H2O <=> Thiamin monophosphate + Orthophosphate

ATP:thiamine-diphosphate phosphotransferase; ATP + Thiamin diphosphate <=> ADP + Thiamin triphosphate

ATP:thiamin-phosphate phosphotransferase; ATP + Thiamin monophosphate <=> ADP + Thiamin diphosphate

thiamin-triphosphate phosphohydrolase; Thiamin triphosphate + H2O <=> Thiamin diphosphate + Orthophosphate

ATP:thiamine diphosphotransferase; ATP + Thiamine <=> AMP + Thiamin diphosphate

2-Oxoglutarate + Thiamin diphosphate <=> 3-Carboxy-1-hydroxypropyl-ThPP + CO2

phosphate-monoester phosphohydrolase; Orthophosphoric monoester + H2O <=> Alcohol + Orthophosphate

3'-phosphoadenylyl-sulfate:alcohol sulfotransferase; Alcohol + 3'-Phosphoadenylyl sulfate <=> Alkyl sulfate + Adenosine 3',5'-bisphosphate

phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyl-transferase; Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine <=> UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine + Orthophosphate

uridine triphosphate pyrophosphohydrolase; UTP + H2O <=> UMP + Diphosphate

L-phenylalanine racemase (ATP-hydrolysing); ATP + L-Phenylalanine + H2O <=> AMP + Diphosphate + D-Phenylalanine

farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase; 2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate

ITP phosphohydrolase; ITP + H2O <=> IDP + Orthophosphate

inosine 5'-triphosphate pyrophosphohydrolase; ITP + H2O <=> IMP + Diphosphate

inosine 5'-tetraphosphate phosphohydrolase; Inosine 5'-tetraphosphate + H2O <=> ITP + Orthophosphate

ITP:D-glucose 6-phosphotransferase; ITP + D-Glucose <=> IDP + D-Glucose 6-phosphate

succinate:CoA ligase (IDP-forming); ITP + Succinate + CoA <=> IDP + Orthophosphate + Succinyl-CoA

L-tyrosine:L-arginine ligase (AMP-forming); ATP + L-Tyrosine + L-Arginine <=> AMP + Diphosphate + Kyotorphin

acetyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA

2-phosphonoacetaldehyde phosphonohydrolase; Phosphonoacetaldehyde + H2O <=> Acetaldehyde + Orthophosphate

ethanolamine-phosphate phosphate-lyase (deaminating; acetaldehyde-forming); Ethanolamine phosphate + H2O <=> Acetaldehyde + Ammonia + Orthophosphate

Acetaldehyde + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate

ATP:D-fructose-6-phosphate 1-phosphotransferase; ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate

D-mannitol-1-phosphate:NAD+ 5-oxidoreductase; D-Mannitol 1-phosphate + NAD+ <=> D-Fructose 6-phosphate + NADH + H+

ATP:D-fructose 6-phosphotransferase; ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate

D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming); D-Fructose 6-phosphate + Orthophosphate <=> Acetyl phosphate + D-Erythrose 4-phosphate + H2O

D-fructose-1,6-bisphosphate 1-phosphohydrolase; D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate

beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate

diphosphate:D-fructose-6-phosphate 1-phosphotransferase; Diphosphate + D-Fructose 6-phosphate <=> Orthophosphate + D-Fructose 1,6-bisphosphate

D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate ketol-isomerase(deaminating); D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia

UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase; UDP-glucose + D-Fructose 6-phosphate <=> UDP + Sucrose 6'-phosphate

CTP:D-fructose-6-phosphate 1-phosphotransferase; CTP + D-Fructose 6-phosphate <=> CDP + D-Fructose 1,6-bisphosphate

L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate aminotransferase (hexose isomerizing); L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate

UTP:D-fructose-6-phosphate 1-phosphotransferase; UTP + D-Fructose 6-phosphate <=> UDP + D-Fructose 1,6-bisphosphate

ITP:D-fructose-6-phosphate 1-phosphotransferase; ITP + D-Fructose 6-phosphate <=> IDP + D-Fructose 1,6-bisphosphate

D-glucose-6-phosphate aldose-ketose-isomerase; D-Glucose 6-phosphate <=> D-Fructose 6-phosphate

D-mannose-6-phosphate aldose-ketose-isomerase; D-Mannose 6-phosphate <=> D-Fructose 6-phosphate

urea:carbon-dioxide ligase (ADP-forming); ATP + Urea + HCO3- <=> ADP + Orthophosphate + Urea-1-carboxylate

sucrose:phosphate alpha-D-glucosyltransferase; Sucrose + Orthophosphate <=> D-Fructose + D-Glucose 1-phosphate

sugar-phosphate phosphohydrolase; Sugar phosphate + H2O <=> Sugar + Orthophosphate

sucrose-6F-phosphate phosphohydrolase; Sucrose 6'-phosphate + H2O <=> Sucrose + Orthophosphate

protein-Npi-phospho-L-histidine:sugar phosphotransferase; Sucrose + Protein N(pi)-phospho-L-histidine <=> Sucrose 6-phosphate + Protein histidine

D-sorbitol 6-phosphate:NADP+ 1-oxidoreductase; Sorbitol 6-phosphate + NADP+ <=> D-Glucose 6-phosphate + NADPH + H+

D-glucose-6-phosphate:NADP+ 1-oxidoreductase; D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+

UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; UDP-glucose + D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate

alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase; H2O + alpha,alpha'-Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate

maltose-6'-phosphate 6-phosphoglucohydrolase; H2O + Maltose 6'-phosphate <=> D-Glucose + D-Glucose 6-phosphate

6-phospho-beta-D-glucosyl-(1->4)-D-glucose 6-phosphoglucohydrolase; 6-Phospho-beta-D-glucosyl-(1,4)-D-glucose + H2O <=> D-Glucose + D-Glucose 6-phosphate

sn-glycerol-3-phosphate phosphohydrolase; sn-Glycerol 3-phosphate + H2O <=> Glycerol + Orthophosphate

sn-glycerol-3-phosphate:NAD+ 2-oxidoreductase; sn-Glycerol 3-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+

sn-glycerol-3-phosphate:NADP+ 2-oxidoreductase; sn-Glycerol 3-phosphate + NADP+ <=> Glycerone phosphate + NADPH + H+

sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase; sn-Glycerol 3-phosphate + NADP+ <=> D-Glyceraldehyde 3-phosphate + NADPH + H+

sn-glycerol-3-phosphate:oxygen 2-oxidoreductase; sn-Glycerol 3-phosphate + Oxygen <=> Glycerone phosphate + Hydrogen peroxide

ATP:glycerol 3-phosphotransferase; ATP + Glycerol <=> ADP + sn-Glycerol 3-phosphate

sn-glycerol-3-phosphate:(acceptor) 2-oxidoreductase; sn-Glycerol 3-phosphate + FAD <=> Glycerone phosphate + FADH2

sn-glycerol 3-phosphate:quinone oxidoreductase; sn-Glycerol 3-phosphate + Quinone <=> Glycerone phosphate + Hydroquinone

sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase; sn-Glycerol 3-phosphate + D-Glucose <=> Glycerol + D-Glucose 6-phosphate

acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase; sn-Glycerol 3-phosphate + Acyl-CoA <=> 1-Acyl-sn-glycerol 3-phosphate + CoA

UDP-alpha-D-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + 2-(alpha-D-Galactosyl)-sn-glycerol 3-phosphate

UDP-alpha-D-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase; UDP-alpha-D-galactose + sn-Glycerol 3-phosphate <=> UDP + alpha-D-Galactosyl-(1,1')-sn-glycerol 3-phosphate

CDPglycerol phosphoglycerohydrolase; CDP-glycerol + H2O <=> CMP + sn-Glycerol 3-phosphate

CTP:sn-glycerol-3-phosphate cytidylyltransferase; CTP + sn-Glycerol 3-phosphate <=> Diphosphate + CDP-glycerol

glycerophosphodiester glycerophosphohydrolase; Glycerophosphodiester + H2O <=> Alcohol + sn-Glycerol 3-phosphate

ATP:D-fructose 1-phosphotransferase; ATP + D-Fructose <=> ADP + D-Fructose 1-phosphate

ATP:D-fructose 6-phosphotransferase; ATP + D-Fructose <=> ADP + beta-D-Fructose 6-phosphate

D-fructose 2-phosphate phosphatase; beta-D-Fructose 2-phosphate + H2O <=> D-Fructose + Orthophosphate

ITP:D-fructose 6-phosphotransferase; ITP + D-Fructose <=> IDP + D-Fructose 6-phosphate

GDP-mannose mannophosphohydrolase; GDP-mannose + H2O <=> GMP + D-Mannose 1-phosphate

GDP:D-mannose-1-phosphate guanylyltransferase; GDP + D-Mannose 1-phosphate <=> Orthophosphate + GDP-mannose

GTP:alpha-D-mannose-1-phosphate guanylyltransferase; GTP + D-Mannose 1-phosphate <=> Diphosphate + GDP-mannose

L-glutamate:L-cysteine gamma-ligase (ADP-forming); ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine

L-lysine:beta-alanine ligase (ADP-forming); ATP + L-Lysine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-lysine

L-arginine:beta-alanine ligase (ADP-forming); ATP + L-Arginine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-arginine

propanoate:CoA ligase (ADP-forming); ATP + Propanoate + CoA <=> ADP + Orthophosphate + Propanoyl-CoA

propanoyl-CoA:phosphate propanoyltransferase; Propanoyl-CoA + Orthophosphate <=> Propanoyl phosphate + CoA

propanoate:CoA ligase (AMP-forming); ATP + Propanoate + CoA <=> AMP + Diphosphate + Propanoyl-CoA

tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming); ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate

formate:tetrahydrofolate ligase (ADP-forming); Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate

alpha-D-glucose-1-phosphate phosphohydrolase; D-Glucose 1-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate

ATP:alpha-D-glucose-1-phosphate adenylyltransferase; ATP + D-Glucose 1-phosphate <=> Diphosphate + ADP-glucose

ATP:D-glucose-1-phosphate 6-phosphotransferase; ATP + D-Glucose 1-phosphate <=> ADP + alpha-D-Glucose 1,6-bisphosphate

ADP-glucose glucose-1-phosphohydrolase; ADP-glucose + H2O <=> AMP + D-Glucose 1-phosphate

cellobiose:phosphate alpha-D-glucosyltransferase; Cellobiose + Orthophosphate <=> D-Glucose 1-phosphate + D-Glucose

3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase; Laminaribiose + Orthophosphate <=> D-Glucose + D-Glucose 1-phosphate

GTP:alpha-D-glucose-1-phosphate guanylyltransferase; GTP + D-Glucose 1-phosphate <=> Diphosphate + GDP-glucose

UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase; UDP-glucose + alpha-D-Galactose 1-phosphate <=> D-Glucose 1-phosphate + UDP-alpha-D-galactose

CTP:alpha-D-glucose-1-phosphate cytidylyltransferase; CTP + D-Glucose 1-phosphate <=> Diphosphate + CDP-glucose

alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating); 2 D-Glucose 1-phosphate + H2O <=> Maltose + 2 Orthophosphate

alpha-D-glucose 1-phosphate 1,6-phosphomutase; D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate

D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase; 2 D-Glucose 1-phosphate <=> alpha-D-Glucose 1,6-bisphosphate + D-Glucose

IDP phosphohydrolase; inosine diphosphate phosphatase; IDP + H2O <=> IMP + Orthophosphate

uridine 5'-monophosphate phosphohydrolase; UMP + H2O <=> Uridine + Orthophosphate

orotidine-5'-phosphate carboxy-lyase (UMP-forming); Orotidine 5'-phosphate <=> UMP + CO2

UMP:diphosphate phospho-alpha-D-ribosyltransferase; UMP + Diphosphate <=> Uracil + 5-Phospho-alpha-D-ribose 1-diphosphate

P1,P4-bis(5'-uridyl)-tetraphosphate uridylohydrolase; P1,P4-Bis(5'-uridyl) tetraphosphate + H2O <=> UTP + UMP

anthranilate:CoA ligase (AMP-forming); ATP + Anthranilate + CoA <=> AMP + Diphosphate + Anthraniloyl-CoA

2-oxobutanoate:oxygen 2-oxidoreductase (phosphorylating); 2-Oxobutanoate + Orthophosphate + Oxygen <=> Propanoyl phosphate + CO2 + Hydrogen peroxide

dolichyl-phosphate phosphohydrolase; Dolichyl phosphate + H2O <=> Dolichol + Orthophosphate

dolichyl-diphosphate phosphohydrolase; Dolichyl diphosphate + H2O <=> Dolichyl phosphate + Orthophosphate

UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase; UDP-glucose + Dolichyl phosphate <=> UDP + Dolichyl beta-D-glucosyl phosphate

dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase; Dolichyl beta-D-glucosyl phosphate + H2O <=> Dolichyl phosphate + D-Glucose

UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase; UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol

UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Archaeal dolichyl phosphate <=> UDP + Archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate

GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase; GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose

glycerone phosphate phosphohydrolase; Glycerone phosphate + H2O <=> Glycerone + Orthophosphate

ATP:glycerone phosphotransferase; ATP + Glycerone <=> ADP + Glycerone phosphate

phosphoenolpyruvate:glycerone phosphotransferase; Phosphoenolpyruvate + Glycerone <=> Pyruvate + Glycerone phosphate

acyl-CoA:glycerone-phosphate O-acyltransferase; Acyl-CoA + Glycerone phosphate <=> CoA + Acylglycerone phosphate

erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming); Erythrulose 1-phosphate <=> Glycerone phosphate + Formaldehyde

D-glyceraldehyde-3-phosphate aldose-ketose-isomerase; D-Glyceraldehyde 3-phosphate <=> Glycerone phosphate

glycerone-phosphate phosphate-lyase (methylglyoxal-forming); Glycerone phosphate <=> Methylglyoxal + Orthophosphate

CTP:dolichol O-phosphotransferase; CTP + Dolichol <=> CDP + Dolichyl phosphate

ATP:choline phosphotransferase; ATP + Choline <=> ADP + Choline phosphate

3'-phosphoadenylyl-sulfate:choline sulfotransferase; 3'-Phosphoadenylyl sulfate + Choline <=> Adenosine 3',5'-bisphosphate + Choline sulfate

sn-glycero-3-phosphocholine glycerophosphohydrolase; sn-Glycero-3-phosphocholine + H2O <=> Choline + sn-Glycerol 3-phosphate

glycerol-2-phosphate phosphohydrolase; Glycerol 2-phosphate + H2O <=> Glycerol + Orthophosphate

diphosphate:glycerol 1-phosphotransferase; Diphosphate + Glycerol <=> Orthophosphate + sn-Glycerol 1-phosphate

ATP:D-ribose-5-phosphate diphosphotransferase; ATP + D-Ribose 5-phosphate <=> AMP + 5-Phospho-alpha-D-ribose 1-diphosphate

ATP:D-ribose-5-phosphate 1-phosphotransferase; ATP + D-Ribose 5-phosphate <=> ADP + D-Ribose 1,5-bisphosphate

ATP:D-ribose 5-phosphotransferase; ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate

ADP:D-ribose-5-phosphate adenylyltransferase; ADP + D-Ribose 5-phosphate <=> Orthophosphate + ADP-ribose

ribose-5-phosphate:ammonia ligase (ADP-forming); ATP + D-Ribose 5-phosphate + Ammonia <=> ADP + Orthophosphate + 5-Phosphoribosylamine

ADP-ribose ribophosphohydrolase; ADP-ribose + H2O <=> AMP + D-Ribose 5-phosphate

uracil hydro-lyase (adding D-ribose 5-phosphate;pseudouridine-5'-phosphate-forming); Uracil + D-Ribose 5-phosphate <=> Pseudouridine 5'-phosphate + H2O

D-ribose-5-phosphate aldose-ketose-isomerase; D-Ribose 5-phosphate <=> D-Ribulose 5-phosphate

D-ribose 1,5-phosphomutase; alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate

D-glyceraldehyde 3-phosphate:NADP+ oxidoreductase; D-Glyceraldehyde 3-phosphate + NADP+ + H2O <=> 3-Phospho-D-glycerate + NADPH + H+

ATP:D-glyceraldehyde 3-phosphotransferase; ATP + D-Glyceraldehyde <=> ADP + D-Glyceraldehyde 3-phosphate

D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating); D-Glyceraldehyde 3-phosphate + Orthophosphate + NAD+ <=> 3-Phospho-D-glyceroyl phosphate + NADH + H+

D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating); D-Glyceraldehyde 3-phosphate + Orthophosphate + NADP+ <=> 3-Phospho-D-glyceroyl phosphate + NADPH + H+

2-dehydro-3-deoxy-6-phospho-D-galactonate D-glyceraldehyde-3-phospho-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-6-phospho-D-galactonate <=> Pyruvate + D-Glyceraldehyde 3-phosphate

2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); 2-Deoxy-D-ribose 5-phosphate <=> D-Glyceraldehyde 3-phosphate + Acetaldehyde

D-fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate

D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate

D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); D-Tagatose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate

beta-D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming); beta-D-Fructose 1,6-bisphosphate <=> Glycerone phosphate + D-Glyceraldehyde 3-phosphate

1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase; 1-(5-Phospho-D-ribosyl)-ATP + Diphosphate <=> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate

5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating); 5-Phosphoribosylamine + Diphosphate + L-Glutamate <=> L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O

N-(5-phospho-D-ribosyl)anthranilate:pyrophosphate phosphoribosyl-transferase; N-(5-Phospho-D-ribosyl)anthranilate + Diphosphate <=> Anthranilate + 5-Phospho-alpha-D-ribose 1-diphosphate

biotin:CoA ligase (AMP-forming); biotin:apo-[carboxylase] ligase (AMP-forming); ATP:biotin adenylyltransferase; ATP + Biotin <=> Diphosphate + Biotinyl-5'-AMP

biotin:CoA ligase (AMP-forming); ATP + Biotin + CoA <=> AMP + Diphosphate + Biotinyl-CoA

ATP:alpha-D-galactose 1-phosphotransferase; ATP + alpha-D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate

CTP:N-acetylneuraminate cytidylyltransferase; CTP + N-Acetylneuraminate <=> Diphosphate + CMP-N-acetylneuraminate

ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming); ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating); ATP + (R)-5-Diphosphomevalonate <=> ADP + Orthophosphate + Isopentenyl diphosphate + CO2

delta2-isopentenyl-diphosphate:tRNA isopentenyltransferase; Dimethylallyl diphosphate + tRNA adenine <=> Diphosphate + tRNA containing 6-isopentenyladenosine

isopentenyl-diphosphate Delta3-Delta2-isomerase; Isopentenyl diphosphate <=> Dimethylallyl diphosphate

inosine 5'-monophosphate phosphohydrolase; IMP + H2O <=> Inosine + Orthophosphate

5'-inosinate phosphoribohydrolase; IMP + H2O <=> Hypoxanthine + D-Ribose 5-phosphate

IMP:NAD+ oxidoreductase; IMP + NAD+ + H2O <=> Xanthosine 5'-phosphate + NADH + H+

IMP:diphosphate phospho-D-ribosyltransferase; IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate

inosine-5'-phosphate:NADP+ oxidoreductase (aminating); NADH:guanosine-5'-phosphate oxidoreductase (deaminating); IMP + Ammonia + NADP+ <=> GMP + NADPH + H+

IMP:L-aspartate ligase (GDP-forming); GTP + IMP + L-Aspartate <=> GDP + Orthophosphate + N6-(1,2-Dicarboxyethyl)-AMP

dATP:D-glucose 6-phosphotransferase; dATP + D-Glucose <=> dADP + D-Glucose 6-phosphate

dATP:D-fructose 6-phosphotransferase; dATP + D-Fructose <=> dADP + D-Fructose 6-phosphate

pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase; Pyridoxamine phosphate + Pyruvate <=> Pyridoxal phosphate + D-Alanine

D-alanine:D-alanine ligase (ADP-forming); ATP + 2 D-Alanine <=> ADP + Orthophosphate + D-Alanyl-D-alanine

L-histidine:beta-alanine ligase (ADP-forming); ATP + L-Histidine + beta-Alanine <=> ADP + Orthophosphate + Carnosine

butanoyl-CoA:phosphate butanoyltransferase; Butanoyl-CoA + Orthophosphate <=> CoA + Butanoylphosphate

butanoate:CoA ligase (AMP-forming); ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA

1D-myo-inositol 1-phosphate phosphohydrolase; Inositol 1-phosphate + H2O <=> myo-Inositol + Orthophosphate

1D-myo-inositol 4-phosphate phosphohydrolase; myo-Inositol 4-phosphate + H2O <=> myo-Inositol + Orthophosphate

1D-myo-inositol 3-phosphate phosphohydrolase; 1D-myo-Inositol 3-phosphate + H2O <=> myo-Inositol + Orthophosphate

1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase; sn-Glycero-3-phospho-1-inositol + H2O <=> myo-Inositol + sn-Glycerol 3-phosphate

ATP:N-acetyl-D-glucosamine 6-phosphotransferase; ATP + N-Acetyl-D-glucosamine <=> ADP + N-Acetyl-D-glucosamine 6-phosphate

guanosine 5'-monophosphate phosphohydrolase; GMP + H2O <=> Guanosine + Orthophosphate

GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase; GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate

xanthosine-5'-phosphate:ammonia ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP

xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming); ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate

P1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase; P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O <=> GTP + GMP

GDPglucose sugarphosphohydrolase; GDP-glucose + H2O <=> GMP + D-Glucose 1-phosphate

guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase; 3',5'-Cyclic GMP + H2O <=> GMP

3'-phosphoadenylylsulfate:thiol S-sulfotransferase; 3'-Phosphoadenylyl sulfate + Thiol <=> Adenosine 3',5'-bisphosphate + S-Alkyl thiosulfate

3'-phosphoadenylylsulfate:phenol sulfotransferase; 3'-Phosphoadenylyl sulfate + Phenol <=> Adenosine 3',5'-bisphosphate + Aryl sulfate

(S)-malate:CoA ligase (ADP-forming); ATP + (S)-Malate + CoA <=> ADP + Orthophosphate + L-Malyl-CoA

nicotinamide D-ribonucleotide phosphoribohydrolase; Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide + D-Ribose 5-phosphate

nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase; Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate

palmitate:CoA ligase (AMP-forming); ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate

4-hydroxybenzoate:CoA ligase (AMP-forming); ATP + 4-Hydroxybenzoate + CoA <=> AMP + Diphosphate + 4-Hydroxybenzoyl-CoA

phosphatidylcholine cholinephosphohydrolase; Phosphatidylcholine + H2O <=> 1,2-Diacyl-sn-glycerol + Choline phosphate

citrate:CoA ligase (ADP-forming); ATP + Citrate + CoA <=> ADP + Orthophosphate + (3S)-Citryl-CoA

ATP:D-mannose 6-phosphotransferase; ATP + D-Mannose <=> ADP + D-Mannose 6-phosphate

ITP:D-mannose 6-phosphotransferase; ITP + D-Mannose <=> IDP + D-Mannose 6-phosphate

dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase; Dolichyl phosphate D-mannose + H2O <=> Dolichyl phosphate + D-Mannose

dATP:D-mannose 6-phosphotransferase; dATP + D-Mannose <=> dADP + D-Mannose 6-phosphate

2-phosphoglycolate phosphohydrolase; 2-Phosphoglycolate + H2O <=> Glycolate + Orthophosphate

ATP:propanoate phosphotransferase; ATP + Propanoate <=> ADP + Propanoyl phosphate

ATP:propanoate adenylyltransferase; ATP + Propanoate <=> Diphosphate + Propionyladenylate

acetoacetate:CoA ligase (AMP-forming); ATP + Acetoacetate + CoA <=> AMP + Diphosphate + Acetoacetyl-CoA

UTP:1-phospho-alpha-D-glucuronate uridylyltransferase; UTP + D-Glucuronate 1-phosphate <=> Diphosphate + UDP-glucuronate

ATP:carbamate phosphotransferase; ATP + Carbamate <=> ADP + Carbamoyl phosphate

carbamoyl-phosphate:L-lysine carbamoyltransferase; Carbamoyl phosphate + L-Lysine <=> Orthophosphate + L-Homocitrulline

carbamoyl-phosphate:L-aspartate carbamoyltransferase; Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate

carbamoyl-phosphate:L-ornithine carbamoyltransferase; Carbamoyl phosphate + L-Ornithine <=> Orthophosphate + L-Citrulline

carbamoyl-phosphate:putrescine carbamoyltransferase; Carbamoyl phosphate + Putrescine <=> Orthophosphate + N-Carbamoylputrescine

Carbamoyl phosphate <=> Cyclic amidine

S-methyl-5'-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase; 5'-Methylthioadenosine + Orthophosphate <=> Adenine + S-Methyl-5-thio-D-ribose 1-phosphate

long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming); ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]

long-chain-fatty-acid:protein ligase (AMP-forming); ATP + Long-chain fatty acid + [Protein]-L-cysteine <=> AMP + Diphosphate + [Protein]-S-(long-chain-acyl)-L-cysteine

benzoyl phosphate phosphohydrolase; Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate

benzoate:CoA ligase (AMP-forming); ATP + Benzoate + CoA <=> AMP + Diphosphate + Benzoyl-CoA

D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase; D-Xylulose 5-phosphate + Formaldehyde <=> D-Glyceraldehyde 3-phosphate + Glycerone

O-phospho-L-homoserine phosphate-lyase (adding water;L-threonine-forming); O-Phospho-L-homoserine + H2O <=> L-Threonine + Orthophosphate

ATP:ethanolamine O-phosphotransferase; ATP + Ethanolamine <=> ADP + Ethanolamine phosphate

sn-glycero-3-phosphoethanolamine glycerophosphohydrolase; sn-Glycero-3-phosphoethanolamine + H2O <=> Ethanolamine + sn-Glycerol 3-phosphate

UTP:alpha-D-xylose-1-phosphate uridylyltransferase; UTP + alpha-D-Xylose 1-phosphate <=> Diphosphate + UDP-D-xylose

UDP-D-xylose:dolichyl-phosphate D-xylosyltrtansferase; UDP-D-xylose + Dolichyl phosphate <=> UDP + Dolichyl D-xylosyl phosphate

ATP:D-glucuronate 1-phosphotransferase; ATP + D-Glucuronate <=> ADP + D-Glucuronate 1-phosphate

aromatic aldehyde:NADP+ oxidoreductase (ATP-forming); Aromatic aldehyde + AMP + Diphosphate + NADP+ <=> Aromatic acid + NADPH + ATP + H+

ATP:cob(I)alamin Co-beta-adenosyltransferase; ATP + Cob(I)alamin <=> Triphosphate + Cobamide coenzyme

ATP:ceramide 1-phosphotransferase; ATP + N-Acylsphingosine <=> ADP + Ceramide 1-phosphate

ATP:2,3-dihydroxybenzoate adenylyltransferase; ATP + 2,3-Dihydroxybenzoate <=> Diphosphate + (2,3-Dihydroxybenzoyl)adenylate

D-glycerate-3-phosphate phosphohydrolase; 3-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate

ATP:3-phospho-D-glycerate 1-phosphotransferase; ATP + 3-Phospho-D-glycerate <=> ADP + 3-Phospho-D-glyceroyl phosphate

3-phospho-D-glyceroyl phosphate phosphohydrolase; 3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate

GTP:3-phospho-D-glycerate 1-phosphotransferase; GTP + 3-Phospho-D-glycerate <=> GDP + 3-Phospho-D-glyceroyl phosphate

ATP:D-ribulose-5-phosphate 1-phosphotransferase; ATP + D-Ribulose 5-phosphate <=> ADP + D-Ribulose 1,5-bisphosphate

D-ribitol-5-phosphate:NAD+ 2-oxidoreductase; D-Ribitol 5-phosphate + NAD+ <=> D-Ribulose 5-phosphate + NADH + H+

D-ribitol-5-phosphate:NADP+ 2-oxidoreductase; D-Ribitol 5-phosphate + NADP+ <=> D-Ribulose 5-phosphate + NADPH + H+

ATP:D-ribulose 5-phosphotransferase; ATP + D-Ribulose <=> ADP + D-Ribulose 5-phosphate

6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating); 6-Phospho-D-gluconate + NADP+ <=> D-Ribulose 5-phosphate + CO2 + NADPH + H+

D-ribulose-5-phosphate 3-epimerase; D-Ribulose 5-phosphate <=> D-Xylulose 5-phosphate

D-arabinose-5-phosphate aldose-ketose-isomerase; D-Arabinose 5-phosphate <=> D-Ribulose 5-phosphate

nucleoside-triphosphate diphosphohydrolase; Nucleoside triphosphate + H2O <=> Nucleotide + Diphosphate

diisopropyl-fluorophosphate fluorohydrolase; Isoflurophate + H2O <=> Diisopropyl phosphate + Hydrofluoric acid

UDP-alpha-D-galactose:undecaprenyl-phosphate galactose phosphotransferase; UDP-alpha-D-galactose + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + alpha-D-Galactosyl-diphosphoundecaprenol

maltose:phosphate 1-beta-D-glucosyltransferase; Maltose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate

oxalate:CoA ligase (AMP-forming); ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA

adenosine:phosphate alpha-D-ribosyltransferase; Adenosine + Orthophosphate <=> Adenine + alpha-D-Ribose 1-phosphate

adenosine 3'-phosphate phosphohydrolase; 3'-AMP + H2O <=> Adenosine + Orthophosphate

thymidylate 5'-phosphohydrolase; dTMP + H2O <=> Thymidine + Orthophosphate

thymidine:phosphate deoxy-alpha-D-ribosyltransferase; Thymidine + Orthophosphate <=> Thymine + 2-Deoxy-D-ribose 1-phosphate

ATP:D-arabinose 5-phosphotransferase; ATP + D-Arabinose <=> ADP + D-Arabinose 5-phosphate

pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming); Pyridoxamine phosphate + 2-Oxoglutarate <=> Pyridoxal phosphate + D-Glutamate

L-glutamate:methylamine ligase (ADP-forming); ATP + L-Glutamate + Methylamine <=> ADP + Orthophosphate + N5-Methyl-L-glutamine

arachidonate:CoA ligase (AMP-forming); ATP + Arachidonate + CoA <=> AMP + Diphosphate + Arachidonyl-CoA

ATP:beta-D-glucose 6-phosphotransferase; ATP + beta-D-Glucose <=> ADP + beta-D-Glucose 6-phosphate

4-coumarate:CoA ligase (AMP-forming); ATP + 4-Coumarate + CoA <=> AMP + Diphosphate + p-Coumaroyl-CoA

APS:ATP adenylyltransferase; Adenylyl sulfate + ATP <=> Sulfate + P1,P4-Bis(5'-adenosyl)tetraphosphate

acetyl-phosphate:L-lysine N6-acetyltransferase; Acetyl phosphate + L-Lysine <=> Orthophosphate + N6-Acetyl-L-lysine

D-xylulose 5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming); D-Xylulose 5-phosphate + Orthophosphate <=> Acetyl phosphate + D-Glyceraldehyde 3-phosphate + H2O

[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase; Acyl-carrier protein + H2O <=> Pantetheine 4'-phosphate + Apo-[acyl-carrier protein]

CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase; CoA + Apo-[acyl-carrier protein] <=> Adenosine 3',5'-bisphosphate + Acyl-carrier protein

ATP:D-xylulose 5-phosphotransferase; ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate

sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Ribose 5-phosphate + D-Xylulose 5-phosphate

10-formyltetrahydrofolate:L-glutamate ligase (ADP-forming); ATP + 10-Formyltetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + (6R)-10-Formyltetrahydropteroyldiglutamate

dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase; Dimethylallyl diphosphate + L-Tryptophan <=> Diphosphate + 4-(3-Methylbut-2-enyl)-L-tryptophan

dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase; Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranyl diphosphate

dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase; Dimethylallyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Neryl diphosphate

3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase; 3-Phospho-D-glyceroyl phosphate + D-Glucose 1-phosphate <=> 3-Phospho-D-glycerate + alpha-D-Glucose 1,6-bisphosphate

3-phospho-D-glycerate 1,2-phosphomutase; 3-Phospho-D-glyceroyl phosphate <=> 2,3-Bisphospho-D-glycerate

2'-deoxycytidine 5'-monophosphate phosphohydrolase; dCMP + H2O <=> Deoxycytidine + Orthophosphate

dCDP nucleotidohydrolase; dCDP + H2O <=> dCMP + Orthophosphate

dCTP nucleotidohydrolase; deoxycytidine 5'-triphosphate diphosphohydrolase; dCTP + H2O <=> dCMP + Diphosphate

ATP:butanoate 1-phosphotransferase; ATP + Butanoic acid <=> ADP + Butanoylphosphate

5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming); 5-O-(1-Carboxyvinyl)-3-phosphoshikimate <=> Chorismate + Orthophosphate

Nicotinate + Glycine + ATP <=> Nicotinurate + AMP + Diphosphate

5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming); Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+

D-glycerate-2-phosphate phosphohydrolase; 2-Phospho-D-glycerate + H2O <=> D-Glycerate + Orthophosphate

ATP:L-arabinose 1-phosphotransferase; ATP + L-Arabinose <=> ADP + beta-L-Arabinose 1-phosphate

L-xylulose 1-phosphate glycolaldehyde-lyase (glycerone-phosphate-forming); L-Xylulose 1-phosphate <=> Glycerone phosphate + Glycolaldehyde

ATP:alpha-D-glucose 6-phosphotransferase; ATP + alpha-D-Glucose <=> ADP + alpha-D-Glucose 6-phosphate

alpha-D-glucose 6-phosphate phosphohydrolase; alpha-D-Glucose 6-phosphate + H2O <=> alpha-D-Glucose + Orthophosphate

CTP:phosphatidate cytidyltransferase; CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol

CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol + sn-Glycerol 3-phosphate <=> CMP + Phosphatidylglycerophosphate

phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-Acetylneuraminate + Orthophosphate <=> N-Acetyl-D-mannosamine + Phosphoenolpyruvate + H2O

N-acetylneuraminate 9-phosphate phosphohydrolase; N-Acetylneuraminate 9-phosphate + H2O <=> N-Acetylneuraminate + Orthophosphate

D-mannitol-1-phosphate:NADP+ 6-oxidoreductase; D-Mannitol 1-phosphate + NADP+ <=> D-Mannose 6-phosphate + NADPH + H+

D-mannose 6-phosphate 1,6-phosphomutase; D-Mannose 6-phosphate <=> D-Mannose 1-phosphate

D-mannose-6-phosphate aldose-ketose-isomerase; D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate

1,4-alpha-D-glucan:orthophosphate alpha-D-glucosyltransferase; Amylose + Orthophosphate <=> Amylose + D-Glucose 1-phosphate

D-erythrose 4-phosphate:NAD+ oxidoreductase; D-Erythrose 4-phosphate + NAD+ + H2O <=> 4-Phospho-D-erythronate + NADH + H+

phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming); Phosphoenolpyruvate + D-Erythrose 4-phosphate + H2O <=> 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + Orthophospha • • •

sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase; Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + beta-D-Fructose 6-phosphate

sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase; Sedoheptulose 1,7-bisphosphate <=> Glycerone phosphate + D-Erythrose 4-phosphate

beta-D-fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase; beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate

ATP:sedoheptulose 7-phosphate 1-phosphotransferase; ATP + Sedoheptulose 7-phosphate <=> ADP + Sedoheptulose 1,7-bisphosphate

ATP:sedoheptulose 7-phosphate; ATP + Sedoheptulose <=> ADP + Sedoheptulose 7-phosphate

sedoheptulose 1,7-bisphosphate 1-phosphohydrolase; Sedoheptulose 1,7-bisphosphate + H2O <=> Sedoheptulose 7-phosphate + Orthophosphate

2'-deoxyguanosine 5'-triphosphate diphosphohydrolase; dGTP + H2O <=> dGMP + Diphosphate

dGTP triphosphohydrolase; dGTP + H2O <=> Deoxyguanosine + Triphosphate

propanoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA

3'-phosphoadenylyl-sulfate:benzenamine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + Aniline <=> Adenosine 3',5'-bisphosphate + Benzenamine sulfate

inosine:phosphate alpha-D-ribosyltransferase; Inosine + Orthophosphate <=> Hypoxanthine + alpha-D-Ribose 1-phosphate

orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase; Orotidine 5'-phosphate + Diphosphate <=> Orotate + 5-Phospho-alpha-D-ribose 1-diphosphate

uridine:phosphate alpha-D-ribosyltransferase; Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate

uridine 3'-monophosphate phosphohydrolase; 3'-UMP + H2O <=> Uridine + Orthophosphate

N-phosphocreatine hydrolase; Phosphocreatine + H2O <=> Creatine + Orthophosphate

ADP-ribose + H2O <=> alpha-D-Ribose 1-phosphate + AMP

ATP:kanamycin 3'-O-phosphotransferase; ATP + Kanamycin A <=> ADP + Kanamycin A 3'-phosphate

CTP:choline-phosphate cytidylyltransferase; CTP + Choline phosphate <=> Diphosphate + CDP-choline

ATP:L-xylulose 5-phosphotransferase; ATP + L-Xylulose <=> ADP + L-Xylulose 5-phosphate

ATP:L-xylulose 1-phosphotransferase; ATP + L-Xylulose <=> ADP + L-Xylulose 1-phosphate

ATP:pyridoxine 5'-phosphotransferase; ATP + Pyridoxine <=> ADP + Pyridoxine phosphate

pyridoxine-5'-phosphate phosphohydrolase; Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O

gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming); ATP + Glutathione + Spermidine <=> ADP + Orthophosphate + Glutathionylspermidine

ATP:sphingosine 1-phosphotransferase; sphingosine kinase; Sphingosine + ATP <=> Sphingosine 1-phosphate + ADP

caffeate:CoA ligase (AMP-forming); 3,4-dihydroxy-trans-cinnamate:CoA ligase (AMP-forming); ATP + Caffeate + CoA <=> AMP + Diphosphate + Caffeoyl-CoA

GTP:beta-L-fucose-1-phosphate guanylyltransferase; GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose

L-citrulline:L-aspartate ligase (AMP-forming); ATP + L-Citrulline + L-Aspartate <=> AMP + Diphosphate + N-(L-Arginino)succinate

ATP:D-glucosamine 6-phosphotransferase; ATP + D-Glucosamine <=> ADP + D-Glucosamine 6-phosphate

ITP:D-glucosamine 6-phosphotransferase; ITP + D-Glucosamine <=> IDP + D-Glucosamine 6-phosphate

dATP:D-glucosamine 6-phosphotransferase; dATP + D-Glucosamine <=> dADP + D-Glucosamine 6-phosphate

2'-deoxyguanosine 5'-monophosphate phosphohydrolase; dGMP + H2O <=> Deoxyguanosine + Orthophosphate

deoxyguanosine:orthophosphate ribosyltransferase; Deoxyguanosine + Orthophosphate <=> Guanine + 2-Deoxy-D-ribose 1-phosphate

L-histidine:4-aminobutanoate ligase (ADP-forming); ATP + L-Histidine + 4-Aminobutanoate <=> ADP + Orthophosphate + Homocarnosine

geranyl-diphosphate:isopentenyl-diphosphate geranyltrans-transferase; Geranyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + trans,trans-Farnesyl diphosphate

geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]; Geranyl diphosphate + H2O <=> (-)-endo-Fenchol + Diphosphate

geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming); Geranyl diphosphate + H2O <=> Sabinene hydrate + Diphosphate

(+)-bornyl-diphosphate lyase (decyclizing); (+)-Bornyl diphosphate <=> Geranyl diphosphate

geranyldiphosphate diphosphate-lyase (myrcene-forming); Geranyl diphosphate <=> Myrcene + Diphosphate

geranyl-diphosphate diphosphate-lyase (cyclizing, terpinolene-forming); Geranyl diphosphate <=> Terpinolene + Diphosphate

geranyl-diphosphate diphosphate-lyase (cyclizing, comphene-forming); Geranyl diphosphate <=> Camphene + Diphosphate

geranyl-diphosphate diphosphate-lyase [cyclizing; (4S)-limonene-forming]; Geranyl diphosphate <=> (S)-Limonene + Diphosphate

2'-deoxyadenosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dATP + Thioredoxin disulfide + H2O <=> ATP + Thioredoxin

2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP

2'-deoxyuridine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dUDP + Thioredoxin disulfide + H2O <=> Thioredoxin + UDP

2'-deoxyguanosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dGDP + Thioredoxin disulfide + H2O <=> GDP + Thioredoxin

2'-deoxyguanosine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dGTP + Thioredoxin disulfide + H2O <=> GTP + Thioredoxin

adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate -forming); Thioredoxin + 3'-Phosphoadenylyl sulfate <=> Thioredoxin disulfide + Sulfite + Adenosine 3',5'-bisphosphate

2'-deoxyuridine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dCTP + Thioredoxin disulfide + H2O <=> CTP + Thioredoxin

2'-deoxyuridine 5'-triphosphate:oxydized-thioredoxin 2'-oxidoreductase; dUTP + Thioredoxin disulfide + H2O <=> UTP + Thioredoxin

2'-deoxycytidine diphosphate:oxidized-thioredoxin 2'-oxidoreductase; dCDP + Thioredoxin disulfide + H2O <=> Thioredoxin + CDP

phosphatidylglycerol cholinephosphohydrolase; Phosphatidylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + sn-Glycerol 3-phosphate

phosphatidylglycerophosphate phosphohydrolase; Phosphatidylglycerophosphate + H2O <=> Phosphatidylglycerol + Orthophosphate

6-phospho-D-glucono-1,5-lactone lactonohydrolase; D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate

S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase; S-Adenosyl-L-methionine + Ethanolamine phosphate <=> S-Adenosyl-L-homocysteine + N-Methylethanolamine phosphate

CTP:ethanolamine-phosphate cytidylyltransferase; CTP + Ethanolamine phosphate <=> Diphosphate + CDP-ethanolamine

phosphatidylethanolamine ethanolaminephosphohydrolase; Phosphatidylethanolamine + H2O <=> 1,2-Diacyl-sn-glycerol + Ethanolamine phosphate

acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase; Acetyl-CoA + D-Glucosamine 6-phosphate <=> CoA + N-Acetyl-D-glucosamine 6-phosphate

N-acetyl-D-glucosamine-6-phosphate amidohydrolase; N-Acetyl-D-glucosamine 6-phosphate + H2O <=> D-Glucosamine 6-phosphate + Acetate

D-glucosamine 1-phosphate 1,6-phosphomutase; D-glucosamine 1,6-phosphomutase; alpha-D-Glucosamine 1-phosphate <=> D-Glucosamine 6-phosphate

trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase; trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> Diphosphate + Geranylgeranyl diphosphate

geranylgeranyl reductase; Geranylgeranyl diphosphate + 3 H+ + 3 NADPH <=> Phytyl diphosphate + 3 NADP+

geranylgeranyl-diphosphate diphosphate-lyase (cyclizing); Geranylgeranyl diphosphate <=> Casbene + Diphosphate

geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (prephytoene-diphosphate-forming); 2 Geranylgeranyl diphosphate <=> Diphosphate + Prephytoene diphosphate

ent-copalyl-diphosphate lyase; Geranylgeranyl diphosphate <=> ent-Copalyl diphosphate

ATP:D-fructose-1-phosphate 6-phosphotransferase; ATP + D-Fructose 1-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate

diphosphate:beta-D-fructose-6-phosphate 1-phosphotransferase; Diphosphate + beta-D-Fructose 6-phosphate <=> Orthophosphate + beta-D-Fructose 1,6-bisphosphate

N-acetyl-D-glucosamine 6-phosphate 2-epimerase; N-Acetyl-D-glucosamine 6-phosphate <=> N-Acetyl-D-mannosamine 6-phosphate

2'-deoxyadenosine 5'-monophosphate phosphohydrolase; dAMP + H2O <=> Deoxyadenosine + Orthophosphate

dTDP phosphohydrolase; dTDP + H2O <=> dTMP + Orthophosphate

dTTP nucleotidohydrolase; dTTP + H2O <=> dTDP + Orthophosphate

dUTP nucleotidohydrolase; dUTP + H2O <=> dUMP + Diphosphate

2'-deoxyuridine 5'-monophosphate phosphohydrolase; dUMP + H2O <=> Deoxyuridine + Orthophosphate

1,4-alpha-D-glucan:orthophosphate alpha-D-glucosyltransferase; Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate

3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + [Heparan sulfate]-glucosamine <=> Adenosine 3',5'-bisphosphate + [Heparan sulfate]-N-sulfoglucosamine

ATP:thiamine phosphotransferase; ATP + Thiamine <=> ADP + Thiamin monophosphate

thiamin monophosphate phosphohydrolase; Thiamin monophosphate + H2O <=> Thiamine + Orthophosphate

ATP:xylitol 5-phosphotransferase; ATP + Xylitol <=> ADP + Xylitol 5-phosphate

XMP:pyrophosphate phosphoribosyltransferase; Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate

guanosine:phosphate alpha-D-ribosyltransferase; Guanosine + Orthophosphate <=> Guanine + alpha-D-Ribose 1-phosphate

guanosine 3'-phosphate phosphohydrolase; Guanosine 3'-phosphate + H2O <=> Guanosine + Orthophosphate

3'-phosphoadenylylsulfate:quercetin 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin <=> Adenosine 3',5'-bisphosphate + Quercetin 3-sulfate

D-mannitol-1-phosphate phosphohydrolase; D-Mannitol 1-phosphate + H2O <=> Mannitol + Orthophosphate

GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; GDP-glucose + D-Glucose 6-phosphate <=> GDP + alpha,alpha'-Trehalose 6-phosphate

pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase; Pyrimidine 5'-nucleotide + H2O <=> Pyrimidine + D-Ribose 5-phosphate + H+

3'-phosphoadenylylsulfate:chondroitin 4'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 4-sulfate

3'-phosphoadenylylsulfate:chondroitin 6'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Chondroitin <=> Adenosine 3',5'-bisphosphate + Chondroitin 6-sulfate

ATP:polyphosphate phosphotransferase; ATP + Polyphosphate <=> ADP + Polyphosphate

polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + D-Glucose <=> Polyphosphate + D-Glucose 6-phosphate

dolichyl-diphosphate:polyphosphate phosphotransferase; Dolichyl diphosphate + Polyphosphate <=> Dolichyl phosphate + Polyphosphate

polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + beta-D-Glucose <=> Polyphosphate + beta-D-Glucose 6-phosphate

3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase; 3-Phospho-D-glyceroyl phosphate + Polyphosphate <=> 3-Phospho-D-glycerate + Polyphosphate

polyphosphate:D-glucose 6-phosphotransferase; Polyphosphate + alpha-D-Glucose <=> Polyphosphate + alpha-D-Glucose 6-phosphate

ferulate:CoA ligase (AMP-forming); ATP + Ferulate + CoA <=> AMP + Diphosphate + Feruloyl-CoA

sinapate:CoA ligase (AMP-forming); ATP + Sinapate + CoA <=> AMP + Diphosphate + Sinapoyl-CoA

ATP:streptomycin 6-phosphotransferase; ATP + Streptomycin <=> ADP + Streptomycin 6-phosphate

ATP:streptomycin 3''-adenylyltransferase; ATP + Streptomycin <=> Diphosphate + 3''-Adenylylstreptomycin

ATP:streptomycin 3''-phosphotransferase; ATP + Streptomycin <=> ADP + Streptomycin 3''-phosphate

streptomycin-6-phosphate phosphohydrolase; Streptomycin 6-phosphate + H2O <=> Streptomycin + Orthophosphate

7,8-dihydropteroate:L-glutamate ligase (ADP-forming); ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate

formate:dihydrofolate ligase (ADP-forming); ATP + Formate + Dihydrofolate <=> ADP + Orthophosphate + 10-Formyldihydrofolate

1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase; Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate

acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase; Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA

acyl-CoA:2-acyl-sn-glycerol-3-phosphate O-acyltransferase; Acyl-CoA + 2-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate

polynucleotide 3'-phosphohydrolase; 3'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate

5'-phosphopolynucleotide 5'-phosphohydrolase; 5'-Phosphopolynucleotide + H2O <=> Polynucleotide + Orthophosphate

trans-cinnamate:CoA ligase (AMP-forming); ATP + trans-Cinnamate + CoA <=> AMP + Diphosphate + Cinnamoyl-CoA

L-fuculose-1-phosphate lactaldehyde-lyase; L-Fuculose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde

L-rhamnulose-1-phosphate lactaldehyde-lyase; L-Rhamnulose 1-phosphate <=> Glycerone phosphate + (S)-Lactaldehyde

L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating); L-Aspartate 4-semialdehyde + Orthophosphate + NADP+ <=> 4-Phospho-L-aspartate + NADPH + H+

N-ribosylnicotinamide:orthophosphate ribosyltransferase; Nicotinamide-beta-riboside + Orthophosphate <=> Nicotinamide + alpha-D-Ribose 1-phosphate

nicotinate D-ribonucleoside:orthophosphate ribosyltransferase; Nicotinate D-ribonucleoside + Orthophosphate <=> Nicotinate + alpha-D-Ribose 1-phosphate + H+

cytidine:orthophosphate alpha-D-ribosyltransferase; Cytidine + Orthophosphate <=> Cytosine + alpha-D-Ribose 1-phosphate

xanthosine:orthophosphate ribosyltransferase; Xanthosine + Orthophosphate <=> Xanthine + alpha-D-Ribose 1-phosphate

pyrimidine-nucleoside:orthophosphate alpha-D-ribosyltransferase; Pyrimidine nucleoside + Orthophosphate <=> Pyrimidine + alpha-D-Ribose 1-phosphate + H+

5-formyltetrahydrofolate cyclo-ligase (ADP-forming); ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate

ATP:farnesyl-diphosphate phosphotransferase; ATP + trans,trans-Farnesyl diphosphate <=> ADP + Farnesyl triphosphate

2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming); trans,trans-Farnesyl diphosphate <=> Pentalenene + Diphosphate

trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming); trans,trans-Farnesyl diphosphate <=> Trichodiene + Diphosphate

trans,trans-farnesyl-diphosphate farnesyltransferase (bicyclizing); trans,trans-Farnesyl diphosphate <=> Aristolochene + Diphosphate

trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase (isomerizing); trans,trans-Farnesyl diphosphate <=> Nerolidyl diphosphate

2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming); trans,trans-Farnesyl diphosphate <=> delta-Cadinene + Diphosphate

NTP phosphohydrolase; Nucleoside triphosphate + H2O <=> NDP + Orthophosphate

NTP:pyruvate O2-phosphotransferase; Nucleoside triphosphate + Pyruvate <=> NDP + Phosphoenolpyruvate

NTP:deoxycitidine 5'-phosphotransferase; Nucleoside triphosphate + Deoxycytidine <=> NDP + dCMP

nicotinamide ribonucleotide phosphohydrolase; Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate

dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase; dTTP + D-Glucose 1-phosphate <=> Diphosphate + dTDP-glucose

dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase; dTTP + alpha-D-Galactose 1-phosphate <=> Diphosphate + dTDP-galactose

dUTP nucleotidohydrolase; dUTP + H2O <=> dUDP + Orthophosphate

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase; Indoleglycerol phosphate <=> Indole + D-Glyceraldehyde 3-phosphate

3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase; Acetoin + D-Ribose 5-phosphate <=> Acetaldehyde + 1-Deoxy-D-altro-heptulose 7-phosphate

3'-phosphoadenylylsulfate:estrone 3-sulfotransferase; 3'-Phosphoadenylyl sulfate + Estrone <=> Adenosine 3',5'-bisphosphate + Estrone 3-sulfate

cytidine 3'-phosphate phosphohydrolase; 3'-CMP + H2O <=> Cytidine + Orthophosphate

glutarate:CoA ligase (ADP-forming); ATP + Glutarate + CoA <=> ADP + Orthophosphate + Glutaryl-CoA

itaconate:CoA ligase (ADP-forming); ATP + Itaconate + CoA <=> ADP + Orthophosphate + Itaconyl-CoA

itaconate:CoA ligase (GDP-forming); GTP + Itaconate + CoA <=> GDP + Orthophosphate + Itaconyl-CoA

itaconate:CoA ligase (IDP-forming); ITP + Itaconate + CoA <=> IDP + Orthophosphate + Itaconyl-CoA

ATP:shikimate 3-phosphotransferase; ATP + Shikimate <=> ADP + Shikimate 3-phosphate

ATP:erythritol 4-phosphotransferase; ATP + Erythritol <=> ADP + D-Erythritol 4-phosphate

NTP:gentamicin 2''-nucleotidyltransferase; Nucleoside triphosphate + Gentamicin <=> Diphosphate + 2''-Nucleotidylgentamicin

ATP:L-ribulose 5-phosphotransferase; ATP + L-Ribulose <=> ADP + L-Ribulose 5-phosphate

cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming); Benzoyl-CoA + Reduced ferredoxin + 2 ATP + 2 H2O <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Oxidized ferredoxin + 2 Orthophosphate + 2 ADP

sphinganine-1-phosphate pamlmitaldehyde-lyase; Sphinganine 1-phosphate <=> Ethanolamine phosphate + Hexadecanal

(R)-pantoate:beta-alanine ligase (AMP-forming); ATP + (R)-Pantoate + beta-Alanine <=> AMP + Diphosphate + Pantothenate

deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase; deoxyuridine:orthophosphate ribosyltransferase; Deoxyuridine + Orthophosphate <=> Uracil + 2-Deoxy-D-ribose 1-phosphate

ATP:pyridoxal 5'-phosphotransferase; ATP + Pyridoxamine <=> ADP + Pyridoxamine phosphate

pyridoxamine-5'-phosphate phosphohydrolase; Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O

trimetaphosphate hydrolase; Trimetaphosphoric acid + H2O <=> Triphosphate

phenylacetate:CoA ligase; ATP + Phenylacetic acid + CoA <=> AMP + Diphosphate + Phenylacetyl-CoA

sphingomyelin cholinephosphohydrolase; Sphingomyelin + H2O <=> N-Acylsphingosine + Choline phosphate

sphingomyelin ceramide-phosphohydrolase; Sphingomyelin + H2O <=> Choline + Ceramide 1-phosphate

deoxyadenosine:orthophosphate ribosyltransferase; Deoxyadenosine + Orthophosphate <=> Adenine + 2-Deoxy-D-ribose 1-phosphate

D-fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase; D-Fructose 1-phosphate <=> Glycerone phosphate + D-Glyceraldehyde

ATP:[protein]-L-tyrosine O-phosphotransferase; ATP + Protein tyrosine <=> ADP + Protein tyrosine phosphate

protein-tyrosine-phosphate phosphohydrolase; Protein tyrosine phosphate + H2O <=> Protein tyrosine + Orthophosphate

3'-phosphoadenylylsulfate:protein-tyrosine O-sulfotransferase; 3'-Phosphoadenylyl sulfate + Protein tyrosine <=> Adenosine 3',5'-bisphosphate + Protein tyrosine-O-sulfate

2-deoxy-D-glucose 6-phosphate phosphohydrolase; 2-Deoxy-D-glucose 6-phosphate + H2O <=> 2-Deoxy-D-glucose + Orthophosphate

CTP:choline-phosphate cytidylyltransferase; CTP + N-Trimethyl-2-aminoethylphosphonate <=> Diphosphate + CMP-N-trimethyl-2-aminoethylphosphonate

sn-glycero-3-phosphocholine cholinephosphohydrolase; sn-Glycero-3-phosphocholine + H2O <=> Glycerol + Choline phosphate

N-acylneuraminate-9-phosphate phosphohydrolase; N-Acylneuraminate 9-phosphate + H2O <=> N-Acylneuraminate + Orthophosphate

CTP:N-acylneuraminate cytidylyltransferase; CTP + N-Acylneuraminate <=> Diphosphate + CMP-N-acylneuraminate

2,3-dehydroacyl-CoA:sn-glycerol-3-phosphate O-acyltransferase; 2,3-Dehydroacyl-CoA + sn-Glycerol 3-phosphate <=> CoA + 1-Acyl-sn-glycerol 3-phosphate

protein-N(pi)-phosphohistidine:D-mannose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Mannose <=> Protein histidine + D-Mannose 6-phosphate

protein-N(pi)-phosphohistidine:D-glucosamine 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Glucosamine <=> Protein histidine + D-Glucosamine 6-phosphate

3'-phosphoadenylylsulfate:quercetin-3-sulfate 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3'-bissulfate

3'-phosphoadenylylsulfate:quercetin-3-sulfate 4'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3-sulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,4'-bissulfate

UTP:1-phospho-alpha-D-galacturonate uridylyltransferase; UDP-D-galacturonate pyrophospholylase; UDP-D-galacturonate + Diphosphate <=> 1-Phospho-alpha-D-galacturonate + UTP

urate-3-ribonucleoside:phosphate D-ribosyltransferase; Urate-3-ribonucleoside + Orthophosphate <=> Urate + alpha-D-Ribose 1-phosphate

glycerol 1,2-cyclic phosphate 2-glycerophosphohydrolase; Glycerol 1,2-cyclic phosphate + H2O <=> DL-Glycerol 1-phosphate

ATP:N-acetyl-L-glutamate 5-phosphotransferase; ATP + N-Acetyl-L-glutamate <=> ADP + N-Acetyl-L-glutamate 5-phosphate

ATP:N-acyl-D-mannosamine 6-phosphotransferase; ATP + N-Acyl-D-mannosamine <=> ADP + N-Acyl-D-mannosamine 6-phosphate

ATP:2-dehydro-D-gluconate 6-phosphate; ATP + 2-Keto-D-gluconic acid <=> ADP + 6-Phospho-2-dehydro-D-gluconate

ADPmannose sugarphosphohydrolase; ADP-mannose + H2O <=> AMP + D-Mannose 1-phosphate

4-hydroxyphenylacetate:CoA ligase (AMP-forming); ATP + 4-Hydroxyphenylacetate + CoA <=> AMP + Diphosphate + 4-Hydroxyphenylacetyl-CoA

D-mannitol-1-phosphate:NAD+ 5-oxidoreductase; D-Mannitol 1-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+

protein-N(pi)-phosphohistidine:mannitol 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + Mannitol <=> Protein histidine + D-Mannitol 1-phosphate

ATP:N-acyl-D-mannosamine 6-phosphotransferase; ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate

N-Acetyl-D-mannosamine + Orthophosphate <=> N-Acetyl-D-mannosamine 6-phosphate + H2O

4-methylene-L-glutamate:ammonia ligase (AMP-forming); ATP + 4-Methylene-L-glutamate + Ammonia <=> AMP + Diphosphate + 4-Methylene-L-glutamine

UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase; UDP-glucose + Poly(ribitol phosphate) <=> UDP + beta-D-Glucosylpoly(ribitol phosphate)

UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase; UDP-N-acetyl-alpha-D-glucosamine + Poly(ribitol phosphate) <=> UDP + N-Acetyl-D-glucosaminyl-poly(ribitol phosphate)

D-alanine:poly(ribitol phosphate) ligase (AMP-forming); ATP + D-Alanine + Poly(ribitol phosphate) <=> AMP + Diphosphate + O-D-Alanyl-poly(ribitol phosphate)

xanthosine 5'-phosphate phosphohydrolase; Xanthosine 5'-phosphate + H2O <=> Xanthosine + Orthophosphate

XTP pyrophosphohydrolase; XTP diphosphohydrolase (diphosphate-forming); XTP + H2O <=> Xanthosine 5'-phosphate + Diphosphate

D-Glyceraldehyde 3-phosphate + Pyruvate <=> 5-(2-Hydroxyethyl)-4-methylthiazole

L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]; L-Serine + Indoleglycerol phosphate <=> L-Tryptophan + D-Glyceraldehyde 3-phosphate + H2O

alpha,alpha-trehalose:orthophosphate beta-D-glucosyltransferase; alpha,alpha-Trehalose + Orthophosphate <=> D-Glucose + beta-D-Glucose 1-phosphate

beta-D-glucose 1-phosphate 1,6-phosphomutase; beta-D-Glucose 1-phosphate <=> beta-D-Glucose 6-phosphate

D-fructose-2,6-bisphosphate 6-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 2-phosphate + Orthophosphate

D-fructose-2,6-bisphosphate 2-phosphohydrolase; beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate

ATP:D-fructose-6-phosphate 2-phosphotransferase; ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 2,6-bisphosphate

beta-D-glucose-6-phosphate:NADP+ 1-oxoreductase; beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+

UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase; UDP-glucose + alpha-D-Glucose 6-phosphate <=> UDP + alpha,alpha'-Trehalose 6-phosphate

protein-N(pi)-phosphohistidine:D-glucose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Glucose <=> Protein histidine + alpha-D-Glucose 6-phosphate

alpha-D-glucose 6-phosphate ketol-isomerase; alpha-D-Glucose 6-phosphate <=> beta-D-Glucose 6-phosphate

alpha-D-glucose 6-phosphate ketol-isomerase; alpha-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate

gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming); ATP + gamma-L-Glutamyl-L-cysteine + beta-Alanine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteinyl-beta-alanine

deoxyinosine:orthophosphate ribosyltransferase; Deoxyinosine + Orthophosphate <=> Hypoxanthine + 2-Deoxy-D-ribose 1-phosphate

2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase; 2-Deoxy-D-ribose 1-phosphate <=> 2-Deoxy-D-ribose 5-phosphate

ATP:2-deoxy-D-ribose 5-phosphotransferase; 2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP

deoxyribonucleotide 3'-phosphohydrolase; Deoxynucleoside 3'-phosphate + H2O <=> Deoxynucleoside + Orthophosphate

1-Acyl-sn-glycerol 3-phosphate + NADP+ <=> Acylglycerone phosphate + NADPH + H+

ATP:acylglycerol 3-phosphotransferase; ATP + 1-Acylglycerol <=> ADP + 1-Acyl-sn-glycerol 3-phosphate

ATP:acylglycerol 3-phosphotransferase; ATP + 2-Acylglycerol <=> ADP + 2-Acyl-sn-glycerol 3-phosphate

2,3-dehydroacyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase; 2,3-Dehydroacyl-CoA + 1-Acyl-sn-glycerol 3-phosphate <=> CoA + Phosphatidate

phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-acylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating); N-Acylneuraminate 9-phosphate + Orthop • • •

N-acyl-D-glucosamine 6-phosphate 2-epimerase; N-Acyl-D-mannosamine 6-phosphate <=> N-Acyl-D-glucosamine 6-phosphate

trehalose-6-phosphate phosphohydrolase; alpha,alpha'-Trehalose 6-phosphate + H2O <=> alpha,alpha-Trehalose + Orthophosphate

alpha,alpha-Trehalose + Protein N(pi)-phospho-L-histidine <=> alpha,alpha'-Trehalose 6-phosphate + Protein histidine

UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanine + D-Glutamate <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + L-Lysine <=> ADP + Orthophosphate + UDP-N-acety • • •

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminoheptanedioate ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + m • • •

cholate:CoA ligase (AMP-forming); ATP + Cholic acid + CoA <=> AMP + Diphosphate + Choloyl-CoA

P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase; P1,P4-Bis(5'-xanthosyl) tetraphosphate + H2O <=> XTP + Xanthosine 5'-phosphate

3'-phosphoadenylylsulfate:amine N-sulfotransferase; 3'-Phosphoadenylyl sulfate + Amine <=> Adenosine 3',5'-bisphosphate + Sulfamate

serine-phosphoethanolamine ethanolaminephosphohydrolase; L-Serine-phosphoethanolamine + H2O <=> L-Serine + Ethanolamine phosphate

3'-phosphoadenylylsulfate:cortisol 21-sulfotransferase; 3'-Phosphoadenylyl sulfate + Cortisol <=> Adenosine 3',5'-bisphosphate + Cortisol 21-sulfate

ATP:D-hexose 6-phosphotransferase; ATP + D-Hexose <=> ADP + D-Hexose 6-phosphate

ITP:D-hexose 6-phosphotransferase; ITP + D-Hexose <=> IDP + D-Hexose 6-phosphate

dATP:D-hexose 6-phosphotransferase; dATP + D-Hexose <=> dADP + D-Hexose 6-phosphate

D-O-phosphoserine phosphohydrolase; O-Phospho-D-serine + H2O <=> D-Serine + Orthophosphate

ATP:D-hexose 6-phosphotransferase; ATP + D-Sorbitol <=> ADP + Sorbitol 6-phosphate

sorbitol-6-phosphate phosphohydrolase; Sorbitol 6-phosphate + H2O <=> D-Sorbitol + Orthophosphate

ITP:D-hexose 6-phosphotransferase; ITP + D-Sorbitol <=> IDP + Sorbitol 6-phosphate

dATP:D-hexose 6-phosphotransferase; dATP + D-Sorbitol <=> dADP + Sorbitol 6-phosphate

presqualene-diphosphate diphosphate-lyase (reducing, squalene-forming); Presqualene diphosphate + NADPH + H+ <=> Diphosphate + Squalene + NADP+

ATP:caldesmon phosphotransferase (Ca2+/calmodulin-dependent); ATP + Caldesmon <=> ADP + Caldesmon phosphate

caldesmon-phosphate phosphohydrolase; Caldesmon phosphate + H2O <=> Caldesmon + Orthophosphate

1,4-beta-D-oligo-D-glucan:orthophosphate alpha-D-glucosyltransferase; Cellulose + Orthophosphate <=> Cellulose + D-Glucose 1-phosphate

L-tyrosine:tRNA(Tyr) ligase (AMP-forming); ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)

CTP:D-ribitol-5-phosphate cytidylyltransferase; CTP + D-Ribitol 5-phosphate <=> Diphosphate + CDP-ribitol

ATP:D-tagatose 6-phosphotransferase; ATP + D-Tagatose <=> ADP + D-Tagatose 6-phosphate

L-glutamate:ethylamine ligase (ADP-forming); ATP + L-Glutamate + Ethylamine <=> ADP + Orthophosphate + N5-Ethyl-L-glutamine

nucleotide:nucleoside 5'-phosphotransferase; Nucleoside 5'-phosphate + Deoxynucleoside <=> Nucleoside + Deoxynucleoside 5'-phosphate

carbamoyl-phosphate:oxamate carbamoyltransferase; Carbamoyl phosphate + Oxamate <=> Orthophosphate + Oxalureate

Tryptophan + Dimethylallyl diphosphate <=> Dimethylallyltryptophan + Diphosphate

ATP:pantothenate 4'-phosphotransferase; ATP + Pantetheine <=> ADP + Pantetheine 4'-phosphate

ATP:sphinganine 1-phosphotransferase; ATP + Sphinganine <=> ADP + Sphinganine 1-phosphate

2-furoate:CoA ligase (AMP-forming); ATP + 2-Furoate + CoA <=> AMP + Diphosphate + 2-Furoyl-CoA

ATP:nicotinamide-nucleotide adenylyltransferase; ATP + Nicotinate D-ribonucleotide <=> Diphosphate + Deamino-NAD+

L-histidinol-phosphate phosphohydrolase; L-Histidinol phosphate + H2O <=> L-Histidinol + Orthophosphate

ATP:L-rhamnulose 1-phosphotransferase; ATP + L-Rhamnulose <=> ADP + L-Rhamnulose 1-phosphate

monoterpenyl-diphosphate pyrophosphohydrolase; Monoterpenyl diphosphate + H2O <=> Monoterpenol + Diphosphate

4-nitrophenyl phosphate phosphohydrolase; 4-Nitrophenyl phosphate + H2O <=> 4-Nitrophenol + Orthophosphate

ATP:pantetheine-4'-phosphate adenylyltransferase; ATP + Pantetheine 4'-phosphate <=> Diphosphate + Dephospho-CoA

dephospho-CoA nucleotidohydrolase; Dephospho-CoA + H2O <=> Pantetheine 4'-phosphate + AMP

L-alanine:tRNA(Ala) ligase (AMP-forming); ATP + L-Alanine + tRNA(Ala) <=> AMP + Diphosphate + L-Alanyl-tRNA

polyphosphate phosphohydrolase; Polyphosphate(n) + H2O <=> Polyphosphate(n-1) + Orthophosphate

2-acetolactate pyruvate-lyase (carboxylating); 2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate

3'-ribonucleotide phosphohydrolase; 3'-Ribonucleotide + H2O <=> Ribonucleoside + Orthophosphate

(7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase; 6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate

protein-N(pi)-phosphohistidine:sugar phosphotransferase; Protein N(pi)-phospho-L-histidine + Sugar <=> Protein histidine + Sugar phosphate

UTP:beta-L-arabinose-1-phosphate uridylyltransferase; UTP + beta-L-Arabinose 1-phosphate <=> Diphosphate + UDP-L-arabinose

2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate phosphate-lyase (cyclyzing); 2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate <=> 3-Dehydroquinate + Orthophosphate

indoleacetate:L-lysine ligase (ADP-forming); ATP + Indole-3-acetate + L-Lysine <=> ADP + Orthophosphate + N(6)-[(Indol-3-yl)acetyl]-L-lysine

L-2-aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase; ATP:L-2-aminoadipate 6-O-adenylyltransferase; L-2-Aminoadipate + ATP <=> L-2-Aminoadipate adenylate + Diphosphate

1,3-beta-D-oligoglucan:orthophosphate alpha-D-glucosyltransferase; 1,3-beta-D-Glucan + Orthophosphate <=> 1,3-beta-D-Glucan + D-Glucose 1-phosphate

3'-phosphoadenylylsulfate:renilla luciferin sulfotransferase; 3'-Phosphoadenylyl sulfate + Renilla luciferin <=> Adenosine 3',5'-bisphosphate + Luciferyl sulfate

D-ribulose 1,5-bisphosphate oxygenase; D-Ribulose 1,5-bisphosphate + Oxygen <=> 3-Phospho-D-glycerate + 2-Phosphoglycolate

ADP:alpha-D-aldose-1-phosphate adenylyltransferase; ADP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + ADP-aldose

NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase; NDP + alpha-D-Aldose 1-phosphate <=> Orthophosphate + NDP-aldose

phosphoramidate:hexose 1-phosphotransferase; Phosphoramidate + D-Hexose <=> Ammonia + alpha-D-Hexose 1-phosphate

NTP:hexose-1-phosphate nucleotidyltransferase; Nucleoside triphosphate + alpha-D-Aldose 1-phosphate <=> Diphosphate + NDP-hexose

ATP:myosin-light-chain O-phosphotransferase; ATP + Myosin light chain <=> ADP + Myosin light chain phosphate

[myosin-light-chain]-phosphate phosphohydrolase; Myosin light chain phosphate + H2O <=> Myosin light chain + Orthophosphate

3-Hydroxypropionyl-CoA + Orthophosphate + ADP <=> 3-Hydroxypropanoate + CoA + ATP

ATP:L-fucose 1-phosphotransferase; ATP + L-Fucose <=> ADP + L-Fucose 1-phosphate

7,8-diaminononanoate:carbon-dioxide cyclo-ligase; ATP + 7,8-Diaminononanoate + CO2 <=> ADP + Orthophosphate + Dethiobiotin

N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing); ATP + N-Methylhydantoin + 2 H2O <=> ADP + Orthophosphate + N-Carbamoylsarcosine

UDPglucose:phosphopolyprenol D-glucosyltransferase; UDP-glucose + Polyprenyl phosphate <=> UDP + Polyprenylphosphate-glucose

UDP-N-acetylmuramate:L-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramate + L-Alanine <=> ADP + Orthophosphate + UDP-N-acetylmuramoyl-L-alanine

6-carboxyhyxanoate:CoA ligase (AMP-forming); ATP + Pimelate + CoA <=> AMP + Diphosphate + Pimeloyl-CoA

3'-phosphoadenylylsulfate:desulfoglucosinolate sulfotransferase; 3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <=> Adenosine 3',5'-bisphosphate + Glucotropaeolin

2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase; 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole <=> Diphospha • • •

protein-N(pi)-phosphohistidine:D-fructose 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + D-Fructose <=> Protein histidine + D-Fructose 1-phosphate

Sorbitol 6-phosphate + NADP+ <=> Sorbose 1-phosphate + NADPH + H+

ATP:D-tagatose-6-phosphate 1-phosphotransferase; D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP

CTP:D-tagatose 6-phosphate 1-phosphotransferase; CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate

UTP:D-tagatose 6-phosphate 1-phosphotransferase; UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate

ITP:D-tagatose 6-phosphate 1-phosphotransferase; ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate

D-galactose 6-phosphate ketol-isomerase; D-Galactose 6-phosphate <=> D-Tagatose 6-phosphate

ATP:L-fuculose 1-phosphotransferase; ATP + L-Fuculose <=> ADP + L-Fuculose 1-phosphate

5-amino-2-oxopentanoate:2-oxoglutarate aminotransferase; L-Histidinol phosphate + 2-Oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + L-Glutamate

L-ribulose-5-phosphate 3-epimerase; L-xylulose 5-phosphate 3-epimerase; L-Ribulose 5-phosphate <=> L-Xylulose 5-phosphate

phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); 2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating); 3-Deoxy-D-manno-octul • • •

6-phospho-beta-D-galactoside 6-phosphogalactohydrolase; 6-Phospho-beta-D-galactoside + H2O <=> Alcohol + D-Galactose 6-phosphate

lactose 6-phosphate 6-phosphogalactohydrolase; Lactose 6'-phosphate + H2O <=> beta-D-Glucose + D-Galactose 6-phosphate

ATP:nucleoside-5'-phosphate pyrophosphotransferase; ATP + Nucleoside 5'-phosphate <=> AMP + 5'-Phosphonucleoside 3'-diphosphate

3',5'-cyclic-nucleotide 5'-nucleotidohydrolase; 3',5'-Cyclic nucleotide + H2O <=> Nucleoside 5'-phosphate

N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase; (R)-4'-Phosphopantothenoyl-L-cysteine <=> Pantetheine 4'-phosphate + CO2

2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate

[acetyl-CoA carboxylase] phosphate phosphohydrolase; [Acetyl-CoA carboxylase] phosphate + H2O <=> [Acetyl-CoA carboxylase] + Orthophosphate

N(pi)-methyl-L-histidine:beta-alanine ligase (ADP-forming); ATP + N(pi)-Methyl-L-histidine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-N(pi)-methyl-L-histidine

3'-phosphoadenylylsulfate:quercetin-3,3'-bissulfate 7-sulfotransferase; 3'-Phosphoadenylyl sulfate + Quercetin 3,3'-bissulfate <=> Adenosine 3',5'-bisphosphate + Quercetin 3,3',7-trissulfate

(2R)-2,3-bisphosphoglycerate ligase (cyclizing); 2,3-Bisphospho-D-glycerate + ATP <=> Cyclic 2,3-bisphospho-D-glycerate + ADP + Orthophosphate

L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating); L-Glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> L-Glutamyl 5-phosphate + NADPH + H+

ATP:pseudouridine 5'-phosphotransferase; ATP + Pseudouridine <=> ADP + Pseudouridine 5'-phosphate

3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + Thiamin diphosphate

GTP:alpha-D-hexose-1-phosphate gluanylyltransferase; GTP + alpha-D-Hexose 1-phosphate <=> Diphosphate + GDPhexose

alpha-D-hexose 1-phosphate 1,6-phosphomutase; alpha-D-Hexose 1-phosphate <=> alpha-D-Hexose 6-phosphate

beta-D-glucose 6-phosphate ketol-isomerase; beta-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate

D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase; D-myo-Inositol 1,3-bisphosphate + H2O <=> Inositol 1-phosphate + Orthophosphate

sn-glycero-3-phospho-1-inositol inositolphosphohydrolase; sn-Glycero-3-phospho-1-inositol + H2O <=> Glycerol + Inositol 1-phosphate

1-phosphatidyl-D-myo-inositol inositolphosphohydrolase; 1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol

1D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase; D-myo-Inositol 1,2-cyclic phosphate + H2O <=> Inositol 1-phosphate

nicotinate D-ribonucleotide phosphohydrolase; Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate

nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating); Nicotinate D-ribonucleotide + Diphosphate + CO2 <=> Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate

3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase; 3-Deoxy-D-manno-octulosonate 8-phosphate + H2O <=> 3-Deoxy-D-manno-octulosonate + Orthophosphate

CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase; CTP + 3-Deoxy-D-manno-octulosonate <=> Diphosphate + CMP-3-deoxy-D-manno-octulosonate

dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase; Dolichyl D-xylosyl phosphate + [Protein]-L-serine <=> Dolichyl phosphate + D-Xylosylprotein

1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase; 1-Palmitoylglycerol 3-phosphate + NADP+ <=> Palmitoylglycerone phosphate + NADPH + H+

ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate

ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate

1-phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase; 1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate

1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming); 1-Phosphatidyl-D-myo-inositol <=> D-myo-Inositol 1,2-cyclic phosphate + 1,2-Diacyl-sn-glycerol

myo-inositol-hexakisphosphate 3-phosphohydrolase; Phytic acid + H2O <=> D-myo-Inositol 1,2,4,5,6-pentakisphosphate + Orthophosphate

myo-inositol-hexakisphosphate 4-phosphohydrolase; Phytic acid + H2O <=> Inositol 1,2,3,5,6-pentakisphosphate + Orthophosphate

CTP:N-methylethanolamine-phosphate cytidylyltransferase; CTP + N-Methylethanolamine phosphate <=> Diphosphate + CDP-N-methylethanolamine

methylmalonate:CoA ligase (AMP-forming); Methylmalonate + CoA + ATP <=> (R)-Methylmalonyl-CoA + AMP + Diphosphate

ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase; ATP + 1-Amino-1-deoxy-scyllo-inositol <=> ADP + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate

D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase; 1D-myo-Inositol 1,4-bisphosphate + H2O <=> myo-Inositol 4-phosphate + Orthophosphate

D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase; D-myo-Inositol 1,4,5-trisphosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + Orthophosphate

ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase; ATP + Dihydrostreptomycin 6-phosphate <=> ADP + Dihydrostreptomycin 3'alpha,6-bisphosphate

3'-phosphoadenylylsulfate:alcohol sulfotransferase; 3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate

guanosine 3'-diphosphate 5'-triphosphate 5'-phosphohydrolase; Guanosine 3'-diphosphate 5'-triphosphate + H2O <=> Guanosine 3',5'-bis(diphosphate) + Orthophosphate

nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase; 2',3'-Cyclic nucleotide + H2O <=> Nucleoside 2'-phosphate

nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase; 2',3'-Cyclic nucleotide + H2O <=> Nucleoside 3'-phosphate

D-myo-inositol 1,3,4-trisphosphate 1-phosphohydrolase; 1D-myo-Inositol 1,3,4-trisphosphate + H2O <=> D-myo-Inositol 3,4-bisphosphate + Orthophosphate

ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate

ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate

D-myo-inositol 1,3,4,5-tetrakisphosphate 5-phosphohydrolase; 1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-Inositol 1,3,4-trisphosphate + Orthophosphate

ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase; ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate

D-myo-inositol 1,3,4,5-tetrakisphosphate 3-phosphohydrolase; 1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + Orthophosphate

1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol

N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphrylating); N-Acetyl-L-glutamate 5-semialdehyde + Orthophosphate + NADP+ <=> N-Acetyl-L-glutamate 5-phosphate + NADPH + H+

ATP:[pyruvate dehydrogenase (lipoamide)] phosphotransferase; ATP + [Pyruvate dehydrogenase (acetyl-transferring)] <=> ADP + [Pyruvate dehydrogenase (acetyl-transferring)] phosphate

[pyruvate dehydrogenase (lipoamide)]-phosphate phosphohydrolase; [Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H2O <=> [Pyruvate dehydrogenase (acetyl-transferring)] + Orthophosphate

1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase; 2-Acetyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acetyl-sn-glycerol + Orthophosphate

acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase; Acetyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphate

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase; D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O

phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase; Phosphoenolpyruvate + Shikimate 3-phosphate <=> Orthophosphate + 5-O-(1-Carboxyvinyl)-3-phosphoshikimate

ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase; ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate

ATP:[L-glutamate:ammonia ligase (ADP-forming)] adenylyltransferase; ATP + [L-Glutamate:ammonia ligase (ADP-forming)] <=> Diphosphate + Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]

[L-glutamate:ammonia ligase (ADP-forming)]-O4-(5'-adenylyl)-L-tyrosine:phosphate adenylyltransferase; Adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + Orthophosphate <=> ADP + [L-Glutamate:ammonia ligase (ADP-forming)]

L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amindinotransferase; L-Arginine + 1-Amino-1-deoxy-scyllo-inositol 4-phosphate <=> L-Ornithine + 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate

ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase; ATP + 1D-myo-Inositol 1,3,4,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate

ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase; ATP + 1D-myo-Inositol 3,4,5,6-tetrakisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate

geranoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + Geranoyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-(4-Methylpent-3-en-1-yl)pent-2-enedioyl-CoA

1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase; 1-Guanidino-1-deoxy-scyllo-inositol 4-phosphate + H2O <=> 1-Guanidino-1-deoxy-scyllo-inositol + Orthophosphate

ATP:6-hydroxymethyl-7,8-dihydropterin 6'-diphosphotransferase; ATP + 6-(Hydroxymethyl)-7,8-dihydropterin <=> AMP + 6-Hydroxymethyl-7,8-dihydropterin diphosphate

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase(cyclizing); 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <=> Indoleglycerol phosphate + CO2 + H2O

N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase; N-(5-Phospho-D-ribosyl)anthranilate <=> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate

[3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphate phosphohydrolase; [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate + H2O <=> [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropano • • •

ATP:[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphotransferase; ATP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] <=> ADP + [3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] phosphate

2'-deoxyinosine-5'-triphosphate pyrophosphohydrolase; dITP diphosphohydrolase (diphosphate-forming); dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate

prenyl-diphosphate diphosphohydrolase; Prenyl diphosphate + H2O <=> Prenol + Diphosphate

3'-phosphoadenylylsulfate:keratan 6'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Keratan sulfate <=> Adenosine 3',5'-bisphosphate + Keratan sulfate

ADP-sugar sugarphosphohydrolase; ADP-sugar + H2O <=> AMP + alpha-D-Aldose 1-phosphate

ATP:D-allose 6-phosphotransferase; ATP + D-Allose <=> ADP + D-Allose 6-phosphate

ATP:selenide, water phosphotransferase; ATP + Hydrogen selenide + H2O <=> AMP + Selenophosphoric acid + Orthophosphate

diphthine:ammonia ligase (AMP-forming); ATP + Peptide diphthine + Ammonia + H+ <=> AMP + Diphosphate + Peptide diphthamide

phytanate:CoA ligase (AMP-forming); ATP + Phytanate + CoA <=> AMP + Diphosphate + Phytanoyl-CoA

L-arginine:tRNA(Arg) ligase (AMP-forming); ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)

L-aspartate:tRNAAsp ligase (AMP-forming); ATP + L-Aspartate + tRNA(Asn) <=> AMP + Diphosphate + L-Aspartyl-tRNA(Asn)

L-asparagine:tRNA(Asn) ligase (AMP-forming); ATP + L-Asparagine + tRNA(Asn) <=> AMP + Diphosphate + L-Asparaginyl-tRNA(Asn)

L-cysteine:tRNA(Cys) ligase (AMP-forming); ATP + L-Cysteine + tRNA(Cys) <=> AMP + Diphosphate + L-Cysteinyl-tRNA(Cys)

L-glutamate:tRNA(Gln) ligase (AMP-forming); ATP + L-Glutamate + tRNA(Gln) <=> AMP + Diphosphate + L-Glutamyl-tRNA(Gln)

L-glutamine:tRNA(Gln) ligase (AMP-forming); ATP + L-Glutamine + tRNA(Gln) <=> AMP + Diphosphate + Glutaminyl-tRNA

glycine:tRNA(Gly) ligase (AMP-forming); ATP + Glycine + tRNA(Gly) <=> AMP + Diphosphate + Glycyl-tRNA(Gly)

L-histidine:tRNA(His) ligase (AMP-forming); ATP + L-Histidine + tRNA(His) <=> AMP + Diphosphate + L-Histidyl-tRNA(His)

L-isoleucine:tRNA(Ile) ligase (AMP-forming); ATP + L-Isoleucine + tRNA(Ile) <=> AMP + Diphosphate + L-Isoleucyl-tRNA(Ile)

L-leucine:tRNA(Leu) ligase (AMP-forming); ATP + L-Leucine + tRNA(Leu) <=> AMP + Diphosphate + L-Leucyl-tRNA

L-lysine:tRNALys ligase (AMP-forming); ATP + L-Lysine + tRNA(Lys) <=> AMP + Diphosphate + L-Lysyl-tRNA

L-methionine:tRNAMet ligase (AMP-forming); ATP + L-Methionine + tRNA(Met) <=> AMP + Diphosphate + L-Methionyl-tRNA

L-phenylalanine:tRNA(Ala) ligase (AMP-forming); ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)

L-proline:tRNA(Pro) ligase (AMP-forming); ATP + L-Proline + tRNA(Pro) <=> AMP + Diphosphate + L-Prolyl-tRNA(Pro)

L-serine:tRNA(Ser) ligase (AMP-forming); ATP + L-Serine + tRNA(Ser) <=> AMP + Diphosphate + L-Seryl-tRNA(Ser)

L-threonine:tRNA(Thr) ligase (AMP-forming); ATP + L-Threonine + tRNA(Thr) <=> AMP + Diphosphate + L-Threonyl-tRNA(Thr)

L-tryptophan -tRNA(Trp) ligase (AMP-forming); ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)

L-valine:tRNAVal ligase (AMP-forming); ATP + L-Valine + tRNA(Val) <=> AMP + Diphosphate + L-Valyl-tRNA(Val)

diphosphate:purine nucleoside phosphotransferase; Diphosphate + N-D-Ribosylpurine <=> Orthophosphate + Purine mononucleotide

3'-phosphoadenylylsulfate:galactosylsphingosine sulfotransferase; 3'-Phosphoadenylyl sulfate + Psychosine <=> Adenosine 3',5'-bisphosphate + Psychosine sulfate

ATP:acylglycerol 3-phosphotransferase; ATP + Acylglycerol <=> ADP + Acyl-sn-glycerol 3-phosphate

ATP:D-hamamelose 2'-phosphotransferase; ATP + D-Hamamelose <=> ADP + D-Hamamelose 2(1)-phosphate

ATP:macrolide 2'-O-phosphotransferase; ATP + Oleandomycin <=> ADP + Oleandomycin 2'-O-phosphate

dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase; 2 Dimethylallyl diphosphate + Aspulvinone E <=> 2 Diphosphate + Aspulvinone H

ATP:sedoheptulose 1-phosphotransferase; ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate

glutathionylspermidine:glutathione ligase (ADP-forming); ATP + Glutathionylspermidine + Glutathione <=> ADP + Orthophosphate + Trypanothione

GTP:mRNA guanylyltransferase; GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA

acyl-phosphate:D-hexose phosphotransferase; Acyl phosphate + D-Hexose <=> Carboxylate + D-Hexose phosphate

ATP + Ubiquitin + Protein lysine <=> AMP + Diphosphate + Protein N-ubiquityllysine

magnesium-protoporphyrin IX chelatase; ATP + Protoporphyrin + Magnesium cation + H2O <=> ADP + Orthophosphate + Magnesium protoporphyrin + 2 H+

dATP:depurinated-DNA purinetransferase; dATP + Depurinated DNA <=> Deoxyribose triphosphate + DNA adenine

Glu-tRNA(Gln):L-glutamine amido-ligase (ADP-forming); Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O

poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase; n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate

ATP:D-fructose 6-phosphotransferase; ATP + beta-D-Fructose <=> ADP + beta-D-Fructose 6-phosphate

sucrose 6-phosphate fructohydrolase; Sucrose 6-phosphate + H2O <=> D-Fructose + D-Glucose 6-phosphate

GDPmannose:phosphomannan mannosephosphotransferase; GDP-mannose + Phosphomannan <=> GMP + Phosphomannan mannosephosphate

4-chlorobenzoate:CoA ligase; ATP + 4-Chlorobenzoate + CoA <=> AMP + Diphosphate + 4-Chlorobenzoyl-CoA

ATP:O-alkylglycerone phosphotransferase; ATP + O-Alkylglycerone <=> ADP + O-Alkylglycerone phosphate

3'-phosphoadenylylsulfate:phenolic-steroid sulfotransferase; 3'-Phosphoadenylyl sulfate + Phenolic steroid <=> Adenosine 3',5'-bisphosphate + Steroid O-sulfate

3-(ADP)-2-phosphoglycerate phosphohydrolase; 3-(ADP)-2-phosphoglycerate + H2O <=> 3-(ADP)-glycerate + Orthophosphate

Aryl dialkyl phosphate + H2O <=> Dialkyl phosphate + Phenol

UDP-sugar sugarphosphohydrolase; UDP-sugar + H2O <=> UMP + alpha-D-Aldose 1-phosphate

3'-phosphoadenylylsulfate:taurolithocholate sulfotransferase; 3'-Phosphoadenylyl sulfate + Taurolithocholate <=> Adenosine 3',5'-bisphosphate + Taurolithocholate sulfate

[pyruvate kinase] phosphate phosphohydrolase; [Pyruvate kinase] phosphate + H2O <=> [Pyruvate kinase] + Orthophosphate

ATP:branched-chain-fatty-acid 1-phosphotransferase; ATP + 2-Methylpropanoate <=> ADP + 2-Methylpropanoyl phosphate

3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Galactosylceramide <=> Adenosine 3',5'-bisphosphate + Sulfatide

ATP:myosin-heavy-chain O-phosphotransferase; ATP + Myosin heavy chain <=> ADP + Myosin heavy-chain phosphate

O-succinylbenzoate:CoA ligase (AMP-forming); ATP + 2-Succinylbenzoate + CoA <=> AMP + Diphosphate + 2-Succinylbenzoyl-CoA

phosphoribosyl-ATP pyrophosphohydrolase; 1-(5-Phospho-D-ribosyl)-ATP + H2O <=> Phosphoribosyl-AMP + Diphosphate

photinus-luciferin:oxygen 4-oxidoreductase(decarboxylating,ATP-hydrolysing); Photinus luciferin + Oxygen + ATP <=> Oxidized Photinus luciferin + hn + AMP + Diphosphate + CO2

2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase; Dimethylallyl diphosphate + AMP <=> Diphosphate + N6-(delta2-Isopentenyl)-adenosine 5'-monophosphate

imidazole-4-acetate:5-phosphoribosyl-diphosphate ligase (ADP- and pyrophosphate- forming); ATP + Imidazole-4-acetate + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O <=> ADP + Orthophosphate + 1-(5-Phosphoribosyl)imidazole-4-acetate + Diphosphate

dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase; Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]

protein-N(pi)-phosphohistidine:L-sorbose 1-phosphotransferase; Protein N(pi)-phospho-L-histidine + L-Sorbose <=> Protein histidine + Sorbose 1-phosphate

protein-N(pi)-phosphohistidine:maltose 6'-phosphotransferase; Protein N(pi)-phospho-L-histidine + Maltose <=> Protein histidine + Maltose 6'-phosphate

ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase; ATP + 1-Alkyl-sn-glycerol <=> ADP + 1-Alkyl-sn-glycero-3-phosphate

3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming); ATP + 3-Methylcrotonyl-CoA + HCO3- <=> ADP + Orthophosphate + 3-Methylglutaconyl-CoA

ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase; ATP + 5-Methylthio-D-ribose <=> ADP + S-Methyl-5-thio-D-ribose 1-phosphate

5-phospho-D-ribosylamine:glycine ligase (ADP-forming); ATP + 5-Phosphoribosylamine + Glycine <=> ADP + Orthophosphate + 5'-Phosphoribosylglycinamide

[glycogen-synthase D] phosphohydrolase; [Glycogen-synthase D] + H2O <=> [Glycogen-synthase I] + Orthophosphate

alpha(omega)-dicarboxylic acid:CoA ligase (AMP-forming); ATP + alpha,omega-Dicarboxylic acid + CoA <=> AMP + Diphosphate + omega-Carboxyacyl-CoA

geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase; Geranylgeranyl diphosphate + sn-Glycerol 1-phosphate <=> Diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

1-alkyl-2-acyl-sn-glycero-3-phosphate phosphohydrolase; 2-Acyl-1-alkyl-sn-glycero-3-phosphate + H2O <=> 1-Alkyl-2-acylglycerol + Orthophosphate

2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase; 2-Carboxy-D-arabinitol 1-phosphate + H2O <=> 2-Carboxy-D-arabinitol + Orthophosphate

NAD+:poly(adenosine diphosphate D-ribose)ADP-D-ribosyltransferase; NAD+ + ADP-D-ribosyl-acceptor <=> Nicotinamide + ADP-D-ribosyl-acceptor + H+

6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase; 6-(D-Glucose-1-phospho)-D-mannosylglycoprotein + H2O <=> D-Glucose 1-phosphate + D-Mannosylglycoprotein

2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming); ATP + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine <=> ADP + Orthophosphate + Aminoimidazole ribotide

Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming); L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O

3'-phosphoadenylylsulfate:L-tyrosine-methyl-ester sulfotransferase; 3'-Phosphoadenylyl sulfate + L-Tyrosine methyl ester <=> Adenosine 3',5'-bisphosphate + L-Tyrosine methyl ester 4-sulfate

CTP:N-glycoloylneuraminate cytidylyltransferase; CTP + N-Glycoloyl-neuraminate <=> Diphosphate + CMP-N-glycoloylneuraminate

dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase; Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to pr • • •

prephytoene diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase; Prephytoene diphosphate <=> Diphosphate + 15-cis-Phytoene

dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase; dTDP-L-dihydrostreptose + Streptidine 6-phosphate <=> dTDP + O-(1->4)-alpha-L-Dihydrostreptosyl-streptidine 6-phosphate

(R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing); ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate:L-cysteine ligase; CTP + D-4'-Phosphopantothenate + L-Cysteine <=> CMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine

ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase; ATP + Deoxy-5-methylcytidylate <=> ADP + 5-Methyldeoxycytidine diphosphate

propane-1,2-diol-1-phosphate:NAD+ oxidoreductase; Propane-1,2-diol 1-phosphate + NAD+ <=> Hydroxyacetone phosphate + NADH + H+

tetrahydropteroyl-gamma-polyglutamate:L-glutamate gamma-ligase (ADP-forming); ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)

CTP:ethanolamine-phosphate cytidylyltransferase; CTP + 2-Aminoethylphosphonate <=> Diphosphate + CMP-2-aminoethylphosphonate

2-Aminoethylphosphonate + Hydrogen peroxide <=> Ethanolamine + Orthophosphate

ATP:deoxynucleoside-phosphate phosphotransferase; ATP + Deoxynucleoside 5'-phosphate <=> ADP + 2'-Deoxyribonucleoside diphosphate

oligosaccharide-diphosphodolichol phosphodolichohydrolase; Dolichyl diphosphooligosaccharide + H2O <=> Oligosaccharide phosphate + Dolichyl phosphate

RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming); ATP + RNA 3'-terminal-phosphate <=> AMP + Diphosphate + RNA terminal-2',3'-cyclic-phosphate

carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase; Carbamoyl phosphate + 3-Hydroxymethyl ceph-3-em-4-carboxylate <=> Orthophosphate + 3-Carbamoyloxymethylcephem

2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase; 7,8-Dihydroneopterin 3'-triphosphate <=> 6-Pyruvoyltetrahydropterin + Triphosphate

glycerone phosphate:iminosuccinate alkyltransferase (cyclizing); Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate

2'-deoxyribonucleoside diphosphate:oxidized-thioredoxin 2'-oxidoreductase; 2'-Deoxyribonucleoside diphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside diphosphate + Thioredoxin

1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase; Acylglycerone phosphate + Long-chain alcohol <=> O-Alkylglycerone phosphate + Long-chain acid anion

pyrophosphate:microsomal-membrane-protein O-phosphotransferase; Diphosphate + Microsomal-membrane protein <=> Orthophosphate + O-Phospho-microsomal-membrane protein

2'-deoxyribonucleoside triphosphate:oxydized-thioredoxin 2'-oxidoreductase; Deoxynucleoside triphosphate + Thioredoxin disulfide + H2O <=> Ribonucleoside triphosphate + Thioredoxin

S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase; S-Methyl-3-phospho-1-thio-D-glycerate + H2O <=> S-Methyl-1-thio-D-glycerate + Orthophosphate

2,4-dioxotetrahydropyrimidine-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase; 2,4-Dioxotetrahydropyrimidine D-ribonucleotide + Diphosphate <=> 5,6-Dihydrouracil + 5-Phospho-alpha-D-ribose 1-diphosphate

1-Alkyl-sn-glycero-3-phosphate + NADP+ <=> O-Alkylglycerone phosphate + NADPH + H+

acyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acyltransferase; Acyl-CoA + 1-Alkyl-sn-glycero-3-phosphate <=> CoA + 2-Acyl-1-alkyl-sn-glycero-3-phosphate

1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase; 1-Alkyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-Alkyl-sn-glycero-3-phosphate + Ethanolamine

m7G5'ppp5'X m7GMP phosphohydrolase; 7-Methylguanosine 5'-triphospho-5'-oligonucleotide + H2O <=> 7-Methylguanosine 5'-phosphate + Oligonucleotide 5'-diphosphate

D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming); ATP + D-Alanine + Alanyl-poly(glycerolphosphate) <=> ADP + Orthophosphate + D-Alanyl-alanyl-poly(glycerolphosphate)

D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase; D-myo-Inositol 3,4-bisphosphate + H2O <=> 1D-myo-Inositol 3-phosphate + Orthophosphate

1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide:pyrophosphate phosphoribosyltransferase; 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Diphosphate <=> 5-Amino-4-imidazolecarboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate

biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming); ATP + Holo-[carboxylase] + HCO3- <=> ADP + Orthophosphate + Carboxybiotin-carboxyl-carrier protein

ATP:guanidinoethyyl-methyl-phosphate phosphotransferase; ATP + Guanidinoethyl methyl phosphate <=> ADP + N'-Phosphoguanidinoethyl methyl phosphate

protein-N(pi)-phosphohistidine:lactose 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Lactose <=> Protein histidine + Lactose 6'-phosphate

protein-N(pi)-phosphohistidine:salicin 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Salicin <=> Protein histidine + Salicin 6-phosphate

ATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase; ATP + [Isocitrate dehydrogenase (NADP+)] <=> ADP + [Isocitrate dehydrogenase (NADP+)] phosphate

ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4-O'-phosphotransferase; ATP + Low-density lipoprotein L-serine <=> ADP + Low-density lipoprotein O-phospho-L-serine

phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase; 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate

5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-Methyl-5-thio-D-ribose 1-phosphate <=> S-Methyl-5-thio-D-ribulose 1-phosphate

phosphoenolpyruvate:N-acetyl-D-mannosamine-6-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming); N-acetylneuraminate 9-phosphate pyruvate-lyase (pyruvate-phosphorylating); N-Acetylneuraminate 9-phosphate + • • •

acetate:holo-[citrate-(pro-3S)-lyase] ligase (AMP-forming); ATP + Acetate + Holo-[citrate (pro-3S)-lyase] <=> AMP + Diphosphate + Acetyl-[citrate (pro-3S)-lyase]

5-amino-6-(D-ribitylamino)uracil butanedionetransferase; 5-Amino-6-(1-D-ribitylamino)uracil + L-3,4-Dihydroxybutan-2-one 4-phosphate <=> 6,7-Dimethyl-8-(D-ribityl)lumazine + 2 H2O + Orthophosphate

5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming); ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate

3'-phosphoadenylylsulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase; 3'-Phosphoadenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate <=> Adenosine 3',5'-bisphosphate + UDP-N-acetyl-D-galactosamine 4,6-bissulfate

1-(5-Phosphoribosyl)imidazole-4-acetate + H2O <=> (1-Ribosylimidazole)-4-acetate + Orthophosphate

1-Phosphatidyl-1D-myo-inositol 3-phosphate + 2 ATP <=> Phosphatidylinositol-3,4,5-trisphosphate + 2 ADP

3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming); ATP + 3alpha,7alpha-Dihydroxy-5beta-cholestanate + CoA <=> AMP + Diphosphate + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA

ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase; ATP + 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine <=> ADP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate

phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase; Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate

[poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol polysaccharidetransferase; bactoprenyldiphospho-N-acetylmuramoyl-(N- • • •

geranylgeranyl-diphosphate:3-(O-geranylgeranyl)-sn-glycerol 1-phosphate geranylgeranyltransferase; Geranylgeranyl diphosphate + 3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate <=> Diphosphate + 2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

coenzyme B:coenzyme M:methanophenazine oxidoreductase; Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Dihydromethanophenazine <=> Coenzyme B + Coenzyme M + Methanophenazine

2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase; Coenzyme B + 2-(Methylthio)ethanesulfonate <=> Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + Methane

[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphate phosphohydrolase; [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O <=> [Hydroxymethylglutaryl-CoA reductase (NADPH)] + Orthophosphate

ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase; ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate

UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-beta-D-glucosaminyl 1-phosphate phosphohydrolase; UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + H2O <=> UMP + Lipid X

ATP:[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphotransferase; ATP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] <=> ADP + [Hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate

5-[(5-phospho-1-deoxy-D-ribulos-1-ylamino)methylideneamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate-lyase (L-glutamine-hydrolysing; 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxami • • •

biotin:apo-[acetyl-CoA:carbondioxide ligase (ADP-forming)] ligase (AMP-forming); ATP + Biotin + Apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Acetyl-CoA:carbon-dioxide ligase (ADP-forming)]

biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming); ATP + Biotin + Apo-[methylmalonyl-CoA:pyruvate carboxytransferase] <=> AMP + Diphosphate + [Methylmalonyl-CoA:pyruvate carboxytransferase]

UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:alanyl-D-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)

3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming); ATP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + CoA <=> AMP + Diphosphate + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA

biotin:apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]; ATP + Biotin + Apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [Propionyl-CoA:carbon-dioxide ligase (ADP-forming)]

S-acetylphosphopantetheine:deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)] S-acetyltransferase; S-Acetylphosphopantetheine + Holo-[citrate (pro-3S)-lyase] <=> Pantetheine 4'-phosphate + Acetyl-[citrate (pro-3S)-lyase]

1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming); ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole

N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H2O <=> alpha-Ribazole + Orthophosphate

biotin:apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] ligase (AMP-forming); ATP + Biotin + Apo-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] <=> AMP + Diphosphate + [3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-for • • •

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase; UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + Lipid X <=> UDP + Lipid A disa • • •

UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate:D-alanyl-D-alanine ligase (ADP-forming); ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-Alanyl-D-alanine <=> ADP + Orthophosphate + UDP-N-acety • • •

7,8-dihydroneopterin-3'-triphosphate phosphohydrolase (alkaline optimum); 7,8-Dihydroneopterin 3'-triphosphate + 3 H2O <=> 7,8-Dihydroneopterin + 3 Orthophosphate

7,8-Dihydroneopterin + Orthophosphate <=> Dihydroneopterin phosphate + H2O

7,8-dihydroneopterin 3'-triphosphate diphosphohydrolase; 7,8-Dihydroneopterin 3'-triphosphate + H2O <=> Dihydroneopterin phosphate + Diphosphate

2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate hydrolase; 7,8-Dihydroneopterin 3'-triphosphate + H2O <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine

3'-phosphoadenylylsulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase; 3'-Phosphoadenylyl sulfate + alpha-D-Glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol <=> Adenosine 3',5'-bisphosphate + 6-Sulfo-al • • •

ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-alpha-phosphate 4-O'-phosphotransferase; ATP + Lipid A disaccharide <=> ADP + 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'- • • •

CMP-3-deoxy-D-manno-oct-2-ulosonate:lipid IVA 3-deoxy-D-manno-oct-2-ulosonate transferase; 2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate + CMP-3-deoxy-D-manno-octulosonate <=> 3-Deoxy-D-manno-octul • • •

(S)-2-acetolactate pyruvate-lyase (carboxylating); (S)-2-Acetolactate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + Pyruvate

(S)-2-aceto-2-hydroxybutanoate pyruvate-lyase (carboxylating); 2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate

alpha-tubulin:L-tyrosine ligase (ADP-forming); ATP + Detyrosinated alpha-tubulin + L-Tyrosine <=> alpha-Tubulin + ADP + Orthophosphate

UTP:[protein-PII] uridylyltransferase; UTP + [Protein-PII] <=> Diphosphate + Uridylyl-[protein-PII]

ATP:L-selenomethione S-adenosyltransferase; ATP + L-Selenomethionine + H2O <=> Orthophosphate + Diphosphate + Se-Adenosylselenomethionine

selenomethionine:tRNAMet ligase (AMP-forming); ATP + L-Selenomethionine + tRNA(Met) <=> AMP + Diphosphate + Selenomethionyl-tRNA(Met)

ATP:D-fructose-6-phosphate 1-phosphotransferase; ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate

beta-D-fructose 1,6-bisphosphate 1-phosphohydrolase; beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate

Phytyl diphosphate + Chlorophyllide <=> Bacteriopheophytin + Magnesium cation + Diphosphate

L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting); L-2-Aminoadipate + L-Valine + L-Cysteine + 3 ATP + H2O <=> delta-(L-2-Aminoadipyl)-L-cysteinyl-D-valine + 3 AMP + 3 Diphosphate

ATP:selenate adenylyltransferase; ATP + Selenate <=> Diphosphate + Adenylylselenate

3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+

O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine); O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate

polyisopentenylpyrolinate:4-hydroxybenzoate nonaprenyltransferase; all-trans-Polyprenyl diphosphate + 4-Hydroxybenzoate <=> 4-Hydroxy-3-polyprenylbenzoate + Diphosphate

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-ditrans,octacis-undecaprenol:L-glutamine amidoligase (ADP-forming); ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl- • • •

formamidopyrimidine nucleoside triphosphate amidohydrolase; Formamidopyrimidine nucleoside triphosphate + H2O <=> 2,5-Diaminopyrimidine nucleoside triphosphate + Formate

2,5-diaminopyrimidine nucleoside triphosphate mutase; 2,5-Diaminopyrimidine nucleoside triphosphate <=> 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine

O-phospho-4-hydroxy-L-threonine phospho-lyase (adding water); O-Phospho-4-hydroxy-L-threonine + H2O <=> 4-Hydroxy-L-threonine + Orthophosphate

ent-copalyl-diphosphate diphosphate-lyase; ent-Copalyl diphosphate <=> ent-Kaurene + Diphosphate

3'-phosphoadenylylsulfate:digalactosylceramide 3'-sulfotransferase; 3'-Phosphoadenylyl sulfate + Digalactosylceramide <=> Adenosine 3',5'-bisphosphate + Digalactosylceramide sulfate

protein-N(pi)-phosphohistidine:arbutin 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + Arbutin <=> Protein histidine + Arbutin 6-phosphate

arbutin 6-phosphate glucohydrolase; Arbutin 6-phosphate + H2O <=> Hydroquinone + beta-D-Glucose 6-phosphate

salicin 6-phosphate glucohydrolase; Salicin 6-phosphate + H2O <=> Salicyl alcohol + beta-D-Glucose 6-phosphate

2',3'-cyclic GMP 3'-nucleotidohydrolase; 2',3'-Cyclic GMP + H2O <=> Guanosine 3'-phosphate

N-acetyl-D-galactosamine 6-phosphate amidohydrolase; N-Acetyl-D-galactosamine 6-phosphate + H2O <=> D-Galactosamine 6-phosphate + Acetate

S-adenosyl-L-methionine:[RbcL]-L-lysine N6-methyltransferase; 3 S-Adenosyl-L-methionine + [Ribulose-1,5-bisphosphate carboxylase]-L-lysine + H+ <=> 3 S-Adenosyl-L-homocysteine + [Ribulose-1,5-bisphosphate carboxylase]-N6,N6,N6-trimethyl-L-lysine

reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + Nitrogen + 8 Reduced ferredoxin + 8 H+ + 16 H2O <=> 16 Orthophosphate + 16 ADP + 8 Oxidized ferredoxin + 2 Ammonia + Hydrogen

reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing); 16 ATP + Nitrogen + 4 Reduced flavodoxin + 16 H2O <=> 16 Orthophosphate + 16 ADP + 4 Oxidized flavodoxin + 2 Ammonia + Hydrogen

n ATP + Calmodulin + n Ubiquitin <=> n AMP + n Diphosphate + (Ubiquitin)n-calmodulin

10-formyltetrahydropteroyldiglutamate:L-glutamate gamma-ligase (ADP-forming); n-1 ATP + (6R)-10-Formyltetrahydropteroyldiglutamate + n-1 L-Glutamate <=> n-1 ADP + n-1 Orthophosphate + 10-Formyltetrahydrofolylpolyglutamate

protein-N(pi)-phosphohistidine:N-acetyl-D-glucosamine 6-phosphotransferase; Protein N(pi)-phospho-L-histidine + N-Acetyl-D-glucosamine <=> Protein histidine + N-Acetyl-D-glucosamine 6-phosphate

ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase; Phytic acid + ADP <=> 1D-myo-Inositol 1,3,4,5,6-pentakisphosphate + ATP

ATP:cob(I)yrinic acid-a,c-diamide Cobeta-adenosyltransferase; Cob(I)yrinate a,c diamide + ATP <=> Adenosyl cobyrinate a,c diamide + Triphosphate

Adenosyl cobinamide + ATP <=> Adenosyl cobinamide phosphate + ADP

GTP:adenosylcobinamide-phosphate guanylyltransferase; Adenosyl cobinamide phosphate + GTP <=> Adenosine-GDP-cobinamide + Diphosphate

Hydrogenobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Hydrogenobyrinate a,c diamide + 2 Orthophosphate + 2 L-Glutamate + 2 ADP

Adenosyl cobyrinate a,c diamide + 4 L-Glutamine + 4 ATP + 4 H2O <=> Adenosyl cobyrinate hexaamide + 4 L-Glutamate + 4 Orthophosphate + 4 ADP

hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming); Hydrogenobyrinate a,c diamide + Cobalt ion + ATP + H2O <=> Cob(II)yrinate a,c diamide + Orthophosphate + ADP + H+

carbamoyl-phosphate:deacetylcephalosporin C carbamoyltransferase; Deacetylcephalosporin C + Carbamoyl phosphate <=> O-Carbamoyl-deacetylcephalosporin C + Orthophosphate

Nucleoside + Deoxynucleoside 5'-phosphate <=> Deoxynucleoside + Nucleoside 3'-phosphate

beta-D-galactopyranosyl-(13)-N-acetyl-D-hexosamine:phosphate galactosyltransferase; Lacto-N-biose + Orthophosphate <=> alpha-D-Galactose 1-phosphate + N-Acetyl-D-glucosamine

ADP-alpha-D-glucose:sn-glycerol-3-phosphate 2-alpha-D-glucopyranosyltransferase; ADP-glucose + sn-Glycerol 3-phosphate <=> 2-(alpha-D-Glucosyl)-sn-glycerol 3-phosphate + ADP

acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase; Acetyl-CoA + alpha-D-Glucosamine 1-phosphate <=> CoA + N-Acetyl-alpha-D-glucosamine 1-phosphate

D-arabino-hex-3-ulose-6-phosphate formaldehyde-lyase (D-ribulose-5-phosphate-forming); D-Ribulose 5-phosphate + Formaldehyde <=> D-arabino-Hex-3-ulose 6-phosphate

D-arabino-hex-3-ulose-6-phosphate isomerase; D-arabino-Hex-3-ulose 6-phosphate <=> D-Fructose 6-phosphate

2-deoxy-5-keto-D-gluconic acid 6-phosphate dihydroxyacetone phosphate-lyase; 2-Deoxy-5-keto-D-gluconic acid 6-phosphate <=> 3-Oxopropanoate + Glycerone phosphate

2,4-dichlorobenzoate:CoA ligase; CoA + ATP + 2,4-Dichlorobenzoate <=> Diphosphate + 2,4-Dichlorobenzoyl-CoA + AMP

benzoylacetate:CoA ligase (AMP-forming); 3-Oxo-3-phenylpropanoate + CoA + ATP <=> Diphosphate + Benzoylacetyl-CoA + AMP

acetophenone:carbon-dioxide ligase (ADP-forming); 2 ATP + Acetophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 Orthophosphate + 3-Oxo-3-phenylpropanoate

D-Glyceraldehyde 3-phosphate + L-Arginine <=> L-N2-(2-Carboxyethyl)arginine + Orthophosphate

L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming); L-N2-(2-Carboxyethyl)arginine + ATP <=> Deoxyguanidinoproclavaminic acid + AMP + Diphosphate

reduced ferredoxin:acetylene oxidoreductase (ATP-hydrolysing); Acetylene + Reduced ferredoxin + 2 H+ + ATP + H2O <=> Ethylene + Oxidized ferredoxin + ADP + Orthophosphate

D-Glucose 1-phosphate + Nucleoside triphosphate + Amino group donor + Activated methyl group <=> NDP-N-methyl-L-glucosamine + Orthophosphate

Streptomycin 6-phosphate + NADH + H+ <=> Dihydrostreptomycin 6-phosphate + NAD+

3-(2-Hydroxyphenyl)propanoate + ATP + CoA + FAD + NAD+ <=> Salicylate + AMP + Diphosphate + FADH2 + Acetyl-CoA + NADH + H+

N1-Amidinostreptamine 6-phosphate + L-Arginine <=> Streptidine 6-phosphate + L-Ornithine

farnesyl diphosphate:isopentenyl diphosphate farnesyl cistransferase; trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate <=> trans,trans,cis-Geranylgeranyl diphosphate + Diphosphate

(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units); trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> ditrans,polycis-Polyprenyl diphosphate + n Diphosphate

protein-N(pi)-phosphohistidine:galactitol 1-phosphotransferase; Galactitol + Protein N(pi)-phospho-L-histidine <=> Galactitol 1-phosphate + Protein histidine

galactitol-1-phosphate:NAD oxidoreductase; Galactitol 1-phosphate + NAD+ <=> D-Tagatose 6-phosphate + NADH + H+

L-aspartate:tRNA(Asp) ligase (AMP-forming); tRNA(Asp) + L-Aspartate + ATP <=> L-Aspartyl-tRNA(Asp) + Diphosphate + AMP

L-glutamate:tRNA(Glu) ligase (AMP-forming); tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP

4-hydroxybenzoate carboxy-lyase (phenyl phosphate-forming); Phenolic phosphate + CO2 + H2O <=> 4-Hydroxybenzoate + Orthophosphate

2-dehydro-3-deoxy-6-phospho-D-gluconate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming); 2-Dehydro-3-deoxy-6-phospho-D-gluconate <=> D-Glyceraldehyde 3-phosphate + Pyruvate

D-sorbitol-6-phosphate:NAD 2-oxidoreductase; Sorbitol 6-phosphate + NAD+ <=> beta-D-Fructose 6-phosphate + NADH + H+

all-trans-Octaprenyl diphosphate + Diphosphate <=> all-trans-Heptaprenyl diphosphate + Isopentenyl diphosphate

all-trans-Hexaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Heptaprenyl diphosphate + Diphosphate

all-trans-Pentaprenyl diphosphate + Isopentenyl diphosphate <=> all-trans-Hexaprenyl diphosphate + Diphosphate

all-trans-octaprenyl-diphosphate:4-hydroxybenzoate 3-octaprenyltransferase; all-trans-Octaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Octaprenyl-4-hydroxybenzoate + Diphosphate

all-trans-hexaprenyl diphosphate:4-hydroxybenzoate hexaprenyltransferase; all-trans-Hexaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Hexaprenyl-4-hydroxybenzoate + Diphosphate

Cyclohexane-1-carboxylate + CoA + ATP <=> Cyclohexane-1-carbonyl-CoA + AMP + Diphosphate

ATP:phenol phosphotransferase (AMP-forming); Phenol + ATP + H2O <=> Phenolic phosphate + AMP + Orthophosphate

ATP:undecaprenol phosphotransferase; ATP + di-trans,poly-cis-Undecaprenol <=> ADP + di-trans,poly-cis-Undecaprenyl phosphate

undecaprenyl-diphosphate phosphohydrolase; di-trans,poly-cis-Undecaprenyl diphosphate + H2O <=> di-trans,poly-cis-Undecaprenyl phosphate + Orthophosphate

UDPMurAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase; UDPMurNAc(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + di-trans,poly-cis-Undecaprenyl phosphate <=> UMP + MurAc(oyl-L-Ala-D-gam • • •

UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine:undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine + di-t • • •

CTP: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2-C-Methyl-D-erythritol 4-phosphate + CTP <=> 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol + Diphosphate

1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating); Pyruvate + D-Glyceraldehyde 3-phosphate <=> 1-Deoxy-D-xylulose 5-phosphate + CO2

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing); 2-Phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol <=> 2-C-Methyl-D-erythritol 2,4-cyclodiphosphate + CMP

ATP:D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase; ATP + D-glycero-beta-D-manno-Heptose 1-phosphate <=> Diphosphate + ADP-D-glycero-beta-D-manno-heptose

D-glycero-beta-D-manno-heptose-7-phosphate aldose-ketose-isomerase; Sedoheptulose 7-phosphate <=> D-glycero-beta-D-manno-Heptose 7-phosphate

ATP:D-glycero-beta-D-manno-heptose 7-phosphate 1-phosphotransferase; ATP + D-glycero-beta-D-manno-Heptose 7-phosphate <=> ADP + D-glycero-beta-D-manno-Heptose 1,7-bisphosphate

D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphohydrolase; D-glycero-beta-D-manno-Heptose 1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-Heptose 1-phosphate + Orthophosphate

acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming); Sulfoacetaldehyde + Orthophosphate <=> Acetyl phosphate + Sulfite

ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase; 2-Deoxy-5-keto-D-gluconic acid + ATP <=> 2-Deoxy-5-keto-D-gluconic acid 6-phosphate + ADP

3'-Keto-3'-deoxy-ATP <=> 3'-Keto-3'-deoxy-AMP + Diphosphate

3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate

N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA

N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine

N-Acetyl-N6,O-didemethylpuromycin-5'-phosphate + S-Adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5'-phosphate + S-Adenosyl-L-homocysteine

N-Acetyl-O-demethylpuromycin-5'-phosphate <=> N-Acetyl-O-demethylpuromycin

sn-glycerol-1-phosphate:NAD 2-oxidoreductase; sn-Glycerol 1-phosphate + NAD+ <=> Glycerone phosphate + NADH + H+