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KEGG
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EXPRESSION
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Database: KEGG - Search term: Insulin
KEGG PATHWAY
map04910
Insulin signaling pathway
map04911
Insulin secretion
map04931
Insulin resistance
KEGG ORTHOLOGY
K04526
INS; insulin
K04527
INSR, CD220; insulin receptor [EC:2.7.10.1]
K05086
INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K05087
IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05255
INSL6; insulin-like 6
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KEGG GENES
hsa:3485
K23575 insulin-like growth factor-binding protein 2 | (RefSeq) IGFBP2, IBP2, IGF-BP53; insulin like growth factor binding protein 2
hsa:3640
K21999 insulin-like 3 | (RefSeq) INSL3, RLF, RLNL, ley-I-L; insulin like 3
hsa:1490
K06827 connective tissue growth factor (insulin-like growth factor-binding protein 8) | (RefSeq) CCN2, CTGF, HCS24, IBP-8, IGFBP8, NOV2; cellular communication network factor 2
hsa:8471
K17446 insulin receptor substrate 4 | (RefSeq) IRS4, CHNG9, IRS-4, PY160; insulin receptor substrate 4
hsa:8660
K07187 insulin receptor substrate 2 | (RefSeq) IRS2, IRS-2; insulin receptor substrate 2
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KEGG MGENES
T30005:id30371
K16172 insulin receptor substrate 1 | F1-U_079C10.y_B_pred_1_+_1_61_1_P
T30006:id47698
K26681 insulin-induced protein | F2-V_043O07.y_B_pred_2_-_817_914_2_P
T30007:id47373
K16172 insulin receptor substrate 1 | F2-W_066P21.z_B_pred_3_-_1056_1119_1_P
T30010:id30473
K07187 insulin receptor substrate 2 | In-A_075O23.b_B_pred_4_-_937_1069_1_P
T30013:id26915
K06827 connective tissue growth factor (insulin-like growth factor-binding protein 8) | In-E_058B14.g_B_pred_3_+_1006_1097_0_P
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KEGG COMPOUND
C00723
Insulin
C02288
Reduced insulin
C15906
Glucose-dependent insulinotropic peptide; Gastric inhibitory peptide; GIP
C16124
Insulin-like 3; Relaxin-like factor; INSL 3
C16131
Insulin-like growth factor I; Somatomedin C
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KEGG REACTION
R02824
glutathione:insulin oxidoreductase; Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide
KEGG ENZYME
1.8.1.8
protein-disulfide reductase; protein disulphide reductase; insulin-glutathione transhydrogenase; disulfide reductase; NAD(P)H2:protein-disulfide oxidoreductase
1.8.4.2
protein-disulfide reductase (glutathione); glutathione-insulin transhydrogenase; insulin reductase; reductase, protein disulfide (glutathione); protein disulfide transhydrogenase; glutathione-protein disulfide oxidoreductase; protein disulfide reduc • • •
2.7.10.1
receptor protein-tyrosine kinase; AATK; AATYK; AATYK2; AATYK3; ACH; ALK; anaplastic lymphoma kinase; ARK; ATP:protein-tyrosine O-phosphotransferase (ambiguous); AXL; Bek; Bfgfr; BRT; Bsk; C-FMS; CAK; CCK4; CD115; CD135; CDw135; Cek1; Cek10; Cek11; C • • •
3.4.17.10
carboxypeptidase E; carboxypeptidase H; enkephalin convertase; cobalt-stimulated chromaffin granule carboxypeptidase; insulin granule-associated carboxypeptidase; enkephalin convertase; membrane-bound carboxypeptidase; carboxypeptidase E; enkephalin • • •
3.4.24.56
insulysin; insulinase; insulin-degrading enzyme; insulin protease; insulin proteinase; insulin-degrading neutral proteinase; insulin-specific protease; insulin-glucagon protease; metalloinsulinase; IDE
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KEGG DISEASE
H01228
Insulin-resistant diabetes mellitus with acanthosis nigricans; Type A insulin resistance
H01267
Familial hyperinsulinemic hypoglycemia
H01274
Growth delay due to insulin-like growth factor I resistance; IGF-I resistance
H01909
Hypoinsulinemic hypoglycemia with hemihypertrophy
H02040
Insulin-like growth factor I deficiency
KEGG DRUG
D00085
Insulin (JAN/USP)
D03230
Insulin human (USP/INN); Insulin human (genetical recombination) (JP18); Insulin human (biosynthesis) (JAN); Insulin human (synthesis) (JAN); Humulin (TN)
D03250
Insulin glargine (USAN/INN); Insulin glargine (genetical recombination) (JP18); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 1] (JAN); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 2] (JAN); Lantus (TN)
D04475
Insulin aspart (USP/INN); Insulin aspart (genetical recombination) (JP18); Insulin aspart (genetical recombination) [Insulin aspart biosimilar 1] (JAN); Insulin X 14; NovoRapid (TN); Novolog (TN)
D04477
Insulin lispro (USP/INN); Insulin lispro (genetical recombination) (JAN); Insulin lispro (genetical recombination) [Insulin lispro Biosimilar 1] (JAN); Insulin lispro-aabc; Humalog (TN); Lyumjev (TN)
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KEGG DGROUP
DG01636
Insulin preparation
DG01685
Insulin sensitizer
DG01735
Glinide; Meglitinide; Short acting insulin secretagogues
DG01796
Insulin analog, fast-acting
DG01797
Insulin analog, long-acting
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integrated database retrieval system