Entry |
|
Name |
GDP-mannose 6-dehydrogenase;
guanosine diphosphomannose dehydrogenase;
GDP-mannose dehydrogenase;
guanosine diphosphomannose dehydrogenase;
guanosine diphospho-D-mannose dehydrogenase
|
Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
GDP-D-mannose:NAD+ 6-oxidoreductase
|
Reaction(IUBMB) |
GDP-D-mannose + 2 NAD+ + H2O = GDP-D-mannuronate + 2 NADH + 2 H+ [RN: R00880]
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Reaction(KEGG) |
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Substrate |
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Product |
|
Comment |
Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate.
|
History |
EC 1.1.1.132 created 1972
|
Pathway |
ec00051 | Fructose and mannose metabolism |
ec00520 | Amino sugar and nucleotide sugar metabolism |
|
Orthology |
K00066 | GDP-mannose 6-dehydrogenase |
|
Genes |
» show all
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Reference |
|
Authors |
PREISS J. |
Title |
SUGAR NUCLEOTIDE REACTIONS IN ARTHROBACTER. II. BIOSYNTHESIS OF GUANOSINE DIPHOSPHOMANNURONATE. |
Journal |
J Biol Chem 239:3127-32 (1964) |
Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.132 |
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